Daniel Pletzer

Affiliations

Centre for Microbial Diseases and Immunity Research, Department of Microbiology and Immunology, University of British Columbia, Vancouver, Canada daniel.pletzer@otago.ac.nz bob@hancocklab.com.
Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

ORCID: https://orcid.org/0000-0001-5750-7505

Publications (37)

The Stringent Stress Response Controls Proteases and Global Regulators under Optimal Growth Conditions in Pseudomonas aeruginosa.

mSystems

Avec: Daniel Pletzer , Travis M Blimkie , Heidi Wolfmeier , Yicong Li , Arjun Baghela , Amy H Y Lee , Reza Falsafi , Robert E W Hancock

Biodistribution of Native and Nanoformulated Innate Defense Regulator Peptide 1002.

Molecular pharmaceutics

Avec: Tullio V F Esposito , Colin Blackadar , Lan Wu , Cristina Rodríguez-Rodríguez , Evan F Haney , Daniel Pletzer , Katayoun Saatchi , Robert E W Hancock , Urs O Häfeli

From Data to Decisions: Leveraging Artificial Intelligence and Machine Learning in Combating Antimicrobial Resistance - a Comprehensive Review.

Journal of medical systems

Avec: José M Pérez de la Lastra , Samuel J T Wardell , Tarun Pal , Cesar de la Fuente-Nunez , Daniel Pletzer

Hyaluronic acid-based nanogels improve in vivo compatibility of the anti-biofilm peptide DJK-5.

Nanomedicine : nanotechnology, biology, and medicine

Avec: Sylvia N Kłodzińska , Daniel Pletzer , Negin Rahanjam , Thomas Rades , Robert E W Hancock , Hanne M Nielsen

Dismantling the bacterial virulence program.

Microbial biotechnology

Avec: Morgan A Alford , Daniel Pletzer , Robert E W Hancock

Host Defense Peptide-Mimicking Amphiphilic β-Peptide Polymer (Bu:DM) Exhibiting Anti-Biofilm, Immunomodulatory, and

Journal of medicinal chemistry

Avec: Hashem Etayash , Yuxin Qian , Daniel Pletzer , Qiang Zhang , Jiayang Xie , Ruxin Cui , Chengzhi Dai , Pengcheng Ma , Fan Qi , Runhui Liu , Robert E W Hancock

Ultraviolet-C Irradiation, Heat, and Storage as Potential Methods of Inactivating SARS-CoV-2 and Bacterial Pathogens on Filtering Facepiece Respirators.

Pathogens (Basel, Switzerland)

Avec: Rhodri Harfoot , Deborah B Y Yung , William A Anderson , Cervantée E K Wild , Nicolene Coetzee , Leonor C Hernández , Blair Lawley , Daniel Pletzer , José G B Derraik , Yvonne C Anderson , Miguel E Quiñones-Mateu

Targeting the

Frontiers in microbiology

Avec: Heidi Wolfmeier , Samuel J T Wardell , Leo T Liu , Reza Falsafi , Annette Draeger , Eduard B Babiychuk , Daniel Pletzer , Robert E W Hancock

Surfing motility is a complex adaptation dependent on the stringent stress response in Pseudomonas aeruginosa LESB58.

PLoS pathogens

Avec: Daniel Pletzer , Evelyn Sun , Caleb Ritchie , Lauren Wilkinson , Leo T Liu , Michael J Trimble , Heidi Wolfmeier , Travis M Blimkie , Robert E W Hancock

Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus.

Molecular microbiology

Avec: Deborah Bow Yue Yung , Kathleen Jean Sircombe , Daniel Pletzer

Murine Model of Sinusitis Infection for Screening Antimicrobial and Immunomodulatory Therapies.

Frontiers in cellular and infection microbiology

Avec: Morgan A Alford , Ka-Yee G Choi , Michael J Trimble , Hamid Masoudi , Pavneet Kalsi , Daniel Pletzer , Robert E W Hancock

Inhalable ceftazidime-roflumilast powder targeting infection and inflammation: Influence of incorporating roflumilast into ceftazidime-leucine co-amorphous formulation.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Bishal Raj Adhikari , Shubhra Sinha , Nikita Lyons , Daniel Pletzer , Iain Lamont , Keith C Gordon , Shyamal C Das

Site-Specific Antimicrobial Activity of a Dual-Responsive Ciprofloxacin Prodrug.

Journal of medicinal chemistry

Avec: Catherine L Ross , Aggie Lawer , Kathleen J Sircombe , Daniel Pletzer , Allan B Gamble , Sarah Hook

Contribution of Swarming Motility to Dissemination in a Pseudomonas aeruginosa Murine Skin Abscess Infection Model.

The Journal of infectious diseases

Avec: Shannon R Coleman , Daniel Pletzer , Robert E W Hancock

Aurein-Derived Antimicrobial Peptides Formulated with Pegylated Phospholipid Micelles to Target Methicillin-Resistant Staphylococcus aureus Skin Infections.

ACS infectious diseases

Avec: Prashant Kumar , Daniel Pletzer , Evan F Haney , Negin Rahanjam , John T J Cheng , Marty Yue , Waleed Aljehani , Robert E W Hancock , Jayachandran N Kizhakkedathu , Suzana K Straus

Rough-type and loss of the LPS due to lpx genes deletions are associated with colistin resistance in multidrug-resistant clinical Escherichia coli isolates not harbouring mcr genes.

PloS one

Avec: Mojtaba Moosavian , Nasrin Emam , Daniel Pletzer , Mohammad Savari

A novel mouse model of chronic suppurative otitis media and its use in preclinical antibiotic evaluation.

Science advances

Avec: Kelly M Khomtchouk , Ali Kouhi , Anping Xia , Laurent Adonis Bekale , Solange M Massa , Jolien M Sweere , Daniel Pletzer , Robert E Hancock , Paul L Bollyky , Peter L Santa Maria

Enzymatically releasable polyethylene glycol - host defense peptide conjugates with improved activity and biocompatibility.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Matthew Drayton , Morgan A Alford , Daniel Pletzer , Evan F Haney , Yoan Machado , Haiming D Luo , Christopher M Overall , Jayachandran N Kizhakkedathu , Robert E W Hancock , Suzana K Straus

Antibiofilm and immunomodulatory resorbable nanofibrous filing for dental pulp regenerative procedures.

Bioactive materials

Avec: Mauricio Gonçalves da Costa Sousa , Gabriela Conceição de Almeida , Danilo César Martins Mota , Rosiane Andrade da Costa , Simoni Campos Dias , Samuel Nunes Limberger , Frank Ko , Li Ting Lin , Evan F Haney , Hashem Etayash , Beverlie Baquir , Michael J Trimble , Ya Shen , Zheng Su , Markus Haapasalo , Daniel Pletzer , Letícia Chaves de Souza , Gláucia Schuindt Teixeira , Renato M Silva , Robert E W Hancock , Octavio Luiz Franco , Taia Maria Berto Rezende

Allenamides as a Powerful Tool to Incorporate Diversity: Thia-Michael Lipidation of Semisynthetic Peptides and Access to β-Ketoamides.

Angewandte Chemie (International ed. in English)

Avec: Tae Ung Na , Veronika Sander , Alan J Davidson , Rolland Lin , Yann O Hermant , Madeleine T Hardie Boys , Daniel Pletzer , Georgia Campbell , Scott A Ferguson , Gregory M Cook , Jane R Allison , Margaret Anne Brimble , Brian Hale Northrop , Alan Cameron

Biodistribution and toxicity of innate defense regulator 1018 (IDR-1018).

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Tullio V F Esposito , Cristina Rodríguez-Rodríguez , Colin Blackadar , Evan F Haney , Daniel Pletzer , Robert E W Hancock , Katayoun Saatchi , Urs O Häfeli

Size-Controlled Synthesis of Gold Nanoparticles Tethering Antimicrobial Peptides with Potent Broad-Spectrum Antimicrobial and Antibiofilm Activities.

Molecular pharmaceutics

Avec: Urawadee Rajchakit , Saurabh Lamba , Kelvin Wang , Nikita Lyons , Jun Lu , Simon Swift , Daniel Pletzer , Vijayalekshmi Sarojini

Repurposing ebselen as an inhalable dry powder to treat respiratory tract infections.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Tushar Saha , Nikita Lyons , Deborah Bow Yue Yung , Miguel E Quiñones-Mateu , Daniel Pletzer , Shyamal C Das

Cyclic Derivative of Host-Defense Peptide IDR-1018 Improves Proteolytic Stability, Suppresses Inflammation, and Enhances In Vivo Activity.

Journal of medicinal chemistry

Avec: Hashem Etayash , Daniel Pletzer , Prashant Kumar , Suzana K Straus , Robert E W Hancock

Peptide 1018 inhibits swarming and influences Anr-regulated gene expression downstream of the stringent stress response in Pseudomonas aeruginosa.

PloS one

Avec: Lauren V Wilkinson , Morgan A Alford , Shannon R Coleman , Bing C Wu , Amy H Y Lee , Travis M Blimkie , Manjeet Bains , Reza Falsafi , Daniel Pletzer , Robert E W Hancock

Treatment with a neutrophil elastase inhibitor and ofloxacin reduces P. aeruginosa burden in a mouse model of chronic suppurative otitis media.

NPJ biofilms and microbiomes

Avec: K M Khomtchouk , L I Joseph , B B Khomtchouk , A Kouhi , S Massa , A Xia , I Koliesnik , D Pletzer , P L Bollyky , P L Santa Maria

Towards understanding single-channel characteristics of OccK8 purified from Pseudomonas aeruginosa.

European biophysics journal : EBJ

Avec: Fatma Dogan Guzel , Daniel Pletzer , Araz Norouz Dizaji , Kareem Al-Nahas , Mawadah Bajrai , Mathias Winterhalter

Human organoid biofilm model for assessing antibiofilm activity of novel agents.

NPJ biofilms and microbiomes

Avec: Bing Catherine Wu , Evan F Haney , Noushin Akhoundsadegh , Daniel Pletzer , Michael J Trimble , Alwin E Adriaans , Peter H Nibbering , Robert E W Hancock

Synergistic bactericidal activities of tobramycin with ciprofloxacin and azithromycin against Klebsiella pneumoniae.

The Journal of antibiotics

Avec: Huan Ren , Jingyi Zhang , Jingyi Zhou , Congjuan Xu , Zheng Fan , Xiaolei Pan , Shouyi Li , Yuying Liang , Shuiping Chen , Jun Xu , Penghua Wang , Yanhong Zhang , Guangbo Zhu , Huimin Liu , Yongxin Jin , Fang Bai , Zhihui Cheng , Daniel Pletzer , Weihui Wu

Rapid microwave-based method for the preparation of antimicrobial lignin-capped silver nanoparticles active against multidrug-resistant bacteria.

International journal of pharmaceutics

Avec: Daniel Pletzer , Jason Asnis , Yael N Slavin , Robert E W Hancock , Horacio Bach , Katayoun Saatchi , Urs O Häfeli

Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative Infections.

mBio

Avec: Janine N Copp , Daniel Pletzer , Alistair S Brown , Joris Van der Heijden , Charlotte M Miton , Rebecca J Edgar , Michelle H Rich , Rory F Little , Elsie M Williams , Robert E W Hancock , Nobuhiko Tokuriki , David F Ackerley

Self-Assembly of Antimicrobial Peptoids Impacts Their Biological Effects on

ACS infectious diseases

Avec: Josefine Eilsø Nielsen , Morgan Ashley Alford , Deborah Bow Yue Yung , Natalia Molchanova , John A Fortkort , Jennifer S Lin , Gill Diamond , Robert E W Hancock , Håvard Jenssen , Daniel Pletzer , Reidar Lund , Annelise E Barron

Murepavadin promotes the killing efficacies of aminoglycoside antibiotics against

Antimicrobial agents and chemotherapy

Avec: Xiaoya Wei , Jiacong Gao , Dandan Zhou , Congjuan Xu , Ping Chen , Shuiping Chen , Yanhong Zhang , Xuehua Liu , Guanxian Li , Guangbo Zhu , Huimin Liu , Jinjin Li , Bin Geng , Linlin Gao , Zhihui Cheng , Iain L Lamont , Daniel Pletzer , Yongxin Jin , Shouguang Jin , Weihui Wu

Effectiveness of gold nanoparticles in prevention and treatment of oral mucositis in animal models: a systematic review.

Systematic reviews

Avec: Minati Choudhury , Paul Brunton , Donald Schwass , Daniel Pletzer , Jithendra Ratnayake , George Dias , Geoffrey Tompkins

The ColR/S two-component system is a conserved determinant of host association across Pseudomonas species.

The ISME journal

Avec: Christina L Wiesmann , Yue Zhang , Morgan Alford , Corri D Hamilton , Manisha Dosanjh , David Thoms , Melanie Dostert , Andrew Wilson , Daniel Pletzer , Robert E W Hancock , Cara H Haney

Three-Dimensional Printed Cellulose for Wound Dressing Applications.

3D printing and additive manufacturing

Avec: Farah Fahma , Afrinal Firmanda , Jaydee Cabral , Daniel Pletzer , John Fisher , Bhushan Mahadik , I Wayan Arnata , Dewi Sartika , Anting Wulandari

Using host-mimicking conditions and a murine cutaneous abscess model to identify synergistic antibiotic combinations effective against

Frontiers in cellular and infection microbiology

Avec: Nikita Lyons , Weihui Wu , Yongxin Jin , Iain L Lamont , Daniel Pletzer

Réseau de co-auteurs

Robert E W Hancock 20 collaborations

Evan F Haney 6 collaborations

Morgan A Alford 4 collaborations

Michael J Trimble 4 collaborations

Nikita Lyons 4 collaborations

Travis M Blimkie 3 collaborations

Heidi Wolfmeier 3 collaborations

Reza Falsafi 3 collaborations

Katayoun Saatchi 3 collaborations

Urs O Häfeli 3 collaborations

Hashem Etayash 3 collaborations

Deborah Bow Yue Yung 3 collaborations

Suzana K Straus 3 collaborations

Yongxin Jin 3 collaborations

Weihui Wu 3 collaborations

Amy H Y Lee 2 collaborations

Tullio V F Esposito 2 collaborations

Colin Blackadar 2 collaborations

Cristina Rodríguez-Rodríguez 2 collaborations

Samuel J T Wardell 2 collaborations

Negin Rahanjam 2 collaborations

Miguel E Quiñones-Mateu 2 collaborations

Leo T Liu 2 collaborations

Shyamal C Das 2 collaborations

Shannon R Coleman 2 collaborations

Prashant Kumar 2 collaborations

Jayachandran N Kizhakkedathu 2 collaborations

Congjuan Xu 2 collaborations

Shuiping Chen 2 collaborations

Yanhong Zhang 2 collaborations

Guangbo Zhu 2 collaborations

Huimin Liu 2 collaborations

Zhihui Cheng 2 collaborations

Iain L Lamont 2 collaborations

Yicong Li 1 collaboration

Arjun Baghela 1 collaboration

Lan Wu 1 collaboration

José M Pérez de la Lastra 1 collaboration

Tarun Pal 1 collaboration

Cesar de la Fuente-Nunez 1 collaboration

Sylvia N Kłodzińska 1 collaboration

Thomas Rades 1 collaboration

Hanne M Nielsen 1 collaboration

Yuxin Qian 1 collaboration

Qiang Zhang 1 collaboration

Jiayang Xie 1 collaboration

Ruxin Cui 1 collaboration

Chengzhi Dai 1 collaboration

Pengcheng Ma 1 collaboration

Fan Qi 1 collaboration

Runhui Liu 1 collaboration

Rhodri Harfoot 1 collaboration

Deborah B Y Yung 1 collaboration

William A Anderson 1 collaboration

Cervantée E K Wild 1 collaboration

Nicolene Coetzee 1 collaboration

Leonor C Hernández 1 collaboration

Blair Lawley 1 collaboration

José G B Derraik 1 collaboration

Yvonne C Anderson 1 collaboration

Annette Draeger 1 collaboration

Eduard B Babiychuk 1 collaboration

Evelyn Sun 1 collaboration

Caleb Ritchie 1 collaboration

Lauren Wilkinson 1 collaboration

Kathleen Jean Sircombe 1 collaboration

Ka-Yee G Choi 1 collaboration

Hamid Masoudi 1 collaboration

Pavneet Kalsi 1 collaboration

Bishal Raj Adhikari 1 collaboration

Shubhra Sinha 1 collaboration

Iain Lamont 1 collaboration

Keith C Gordon 1 collaboration

Catherine L Ross 1 collaboration

Aggie Lawer 1 collaboration

Kathleen J Sircombe 1 collaboration

Allan B Gamble 1 collaboration

Sarah Hook 1 collaboration

John T J Cheng 1 collaboration

Marty Yue 1 collaboration

Waleed Aljehani 1 collaboration

Mojtaba Moosavian 1 collaboration

Nasrin Emam 1 collaboration

Mohammad Savari 1 collaboration

Kelly M Khomtchouk 1 collaboration

Ali Kouhi 1 collaboration

Anping Xia 1 collaboration

Laurent Adonis Bekale 1 collaboration

Solange M Massa 1 collaboration

Jolien M Sweere 1 collaboration

Robert E Hancock 1 collaboration

Paul L Bollyky 1 collaboration

Peter L Santa Maria 1 collaboration

Matthew Drayton 1 collaboration

Yoan Machado 1 collaboration

Haiming D Luo 1 collaboration

Christopher M Overall 1 collaboration

Mauricio Gonçalves da Costa Sousa 1 collaboration

Gabriela Conceição de Almeida 1 collaboration

Danilo César Martins Mota 1 collaboration

Rosiane Andrade da Costa 1 collaboration

Simoni Campos Dias 1 collaboration

Samuel Nunes Limberger 1 collaboration

Frank Ko 1 collaboration

Li Ting Lin 1 collaboration

Beverlie Baquir 1 collaboration

Ya Shen 1 collaboration

Zheng Su 1 collaboration

Markus Haapasalo 1 collaboration

Letícia Chaves de Souza 1 collaboration

Gláucia Schuindt Teixeira 1 collaboration

Renato M Silva 1 collaboration

Octavio Luiz Franco 1 collaboration

Taia Maria Berto Rezende 1 collaboration

Tae Ung Na 1 collaboration

Veronika Sander 1 collaboration

Alan J Davidson 1 collaboration

Rolland Lin 1 collaboration

Yann O Hermant 1 collaboration

Madeleine T Hardie Boys 1 collaboration

Georgia Campbell 1 collaboration

Scott A Ferguson 1 collaboration

Gregory M Cook 1 collaboration

Jane R Allison 1 collaboration

Margaret Anne Brimble 1 collaboration

Brian Hale Northrop 1 collaboration

Alan Cameron 1 collaboration

Urawadee Rajchakit 1 collaboration

Saurabh Lamba 1 collaboration

Kelvin Wang 1 collaboration

Jun Lu 1 collaboration

Simon Swift 1 collaboration

Vijayalekshmi Sarojini 1 collaboration

Tushar Saha 1 collaboration

Lauren V Wilkinson 1 collaboration

Bing C Wu 1 collaboration

Manjeet Bains 1 collaboration

K M Khomtchouk 1 collaboration

L I Joseph 1 collaboration

B B Khomtchouk 1 collaboration

A Kouhi 1 collaboration

S Massa 1 collaboration

A Xia 1 collaboration

I Koliesnik 1 collaboration

D Pletzer 1 collaboration

P L Bollyky 1 collaboration

P L Santa Maria 1 collaboration

Fatma Dogan Guzel 1 collaboration

Araz Norouz Dizaji 1 collaboration

Kareem Al-Nahas 1 collaboration

Mawadah Bajrai 1 collaboration

Mathias Winterhalter 1 collaboration

Bing Catherine Wu 1 collaboration

Noushin Akhoundsadegh 1 collaboration

Alwin E Adriaans 1 collaboration

Peter H Nibbering 1 collaboration

Huan Ren 1 collaboration

Jingyi Zhang 1 collaboration

Jingyi Zhou 1 collaboration

Zheng Fan 1 collaboration

Xiaolei Pan 1 collaboration

Shouyi Li 1 collaboration

Yuying Liang 1 collaboration

Jun Xu 1 collaboration

Penghua Wang 1 collaboration

Fang Bai 1 collaboration

Jason Asnis 1 collaboration

Yael N Slavin 1 collaboration

Horacio Bach 1 collaboration

Janine N Copp 1 collaboration

Alistair S Brown 1 collaboration

Joris Van der Heijden 1 collaboration

Charlotte M Miton 1 collaboration

Rebecca J Edgar 1 collaboration

Michelle H Rich 1 collaboration

Rory F Little 1 collaboration

Elsie M Williams 1 collaboration

Nobuhiko Tokuriki 1 collaboration

David F Ackerley 1 collaboration

Josefine Eilsø Nielsen 1 collaboration

Morgan Ashley Alford 1 collaboration

Natalia Molchanova 1 collaboration

John A Fortkort 1 collaboration

Jennifer S Lin 1 collaboration

Gill Diamond 1 collaboration

Håvard Jenssen 1 collaboration

Reidar Lund 1 collaboration

Annelise E Barron 1 collaboration

Xiaoya Wei 1 collaboration

Jiacong Gao 1 collaboration

Dandan Zhou 1 collaboration

Ping Chen 1 collaboration

Xuehua Liu 1 collaboration

Guanxian Li 1 collaboration

Jinjin Li 1 collaboration

Bin Geng 1 collaboration

Linlin Gao 1 collaboration

Shouguang Jin 1 collaboration

Minati Choudhury 1 collaboration

Paul Brunton 1 collaboration

Donald Schwass 1 collaboration

Jithendra Ratnayake 1 collaboration

George Dias 1 collaboration

Geoffrey Tompkins 1 collaboration

Christina L Wiesmann 1 collaboration

Yue Zhang 1 collaboration

Morgan Alford 1 collaboration

Corri D Hamilton 1 collaboration

Manisha Dosanjh 1 collaboration

David Thoms 1 collaboration

Melanie Dostert 1 collaboration

Andrew Wilson 1 collaboration

Cara H Haney 1 collaboration

Farah Fahma 1 collaboration

Afrinal Firmanda 1 collaboration

Jaydee Cabral 1 collaboration

John Fisher 1 collaboration

Bhushan Mahadik 1 collaboration

I Wayan Arnata 1 collaboration

Dewi Sartika 1 collaboration

Anting Wulandari 1 collaboration