Daniel Sasca

Affiliations

Department of Hematology, Oncology and Pneumology, University Medical Center Mainz, Mainz, Germany.

Publications (10)

MoReLife - real-life data support the potential of momelotinib as a safe and effective treatment option for cytopenic myelofibrosis patients.

Annals of hematology

Avec: Stefanie Jilg , Juliana Schwaab , Katja Sockel , Carl C Crodel , Valeska Brueckl , Frank Stegelmann , Madlen Jentzsch , Daniel Sasca , Margarete Moyses , Stephan Fuhrmann , Daniel Gundel , Madlen Caduc , Lino L Teichmann , Florian Heidel , Haifa K Al-Ali , Petro E Petrides

Deficiency of Antioxidative Paraoxonase 2 (Pon2) Leads to Increased Number of Phenotypic LT-HSCs and Disturbed Erythropoiesis.

Oxidative medicine and cellular longevity

Avec: Lisa Spiecker , Ines Witte , Julia Mehlig , Viral Shah , Markus Meyerhöfer , Patricia S Haehnel , Victoria Petermann , Andrea Schüler , Piyush More , Nina Cabezas-Wallscheid , Sven Horke , Andrea Pautz , Andreas Daiber , Daniel Sasca , Thomas Kindler , Hartmut Kleinert

Next generation epigenetic modulators to target myeloid neoplasms.

Current opinion in hematology

Avec: Daniel Sasca , Borhane Guezguez , Michael W M Kühn

Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML.

The Journal of experimental medicine

Avec: Faisal Basheer , George Giotopoulos , Eshwar Meduri , Haiyang Yun , Milena Mazan , Daniel Sasca , Paolo Gallipoli , Ludovica Marando , Malgorzata Gozdecka , Ryan Asby , Olivia Sheppard , Monika Dudek , Lars Bullinger , Hartmut Döhner , Richard Dillon , Sylvie Freeman , Oliver Ottmann , Alan Burnett , Nigel Russell , Elli Papaemmanuil , Robert Hills , Peter Campbell , George S Vassiliou , Brian J P Huntly

Synergistic targeting of FLT3 mutations in AML via combined menin-MLL and FLT3 inhibition.

Blood

Avec: Margarita M Dzama , Marlene Steiner , Johanna Rausch , Daniel Sasca , Jonas Schönfeld , Kerstin Kunz , Martha C Taubert , Gerard M McGeehan , Chun-Wei Chen , Annalisa Mupo , Patricia Hähnel , Matthias Theobald , Thomas Kindler , Richard P Koche , George S Vassiliou , Scott A Armstrong , Michael W M Kühn

HOXA9 forms a repressive complex with nuclear matrix-associated protein SAFB to maintain acute myeloid leukemia.

Blood

Avec: Shuchi Agrawal-Singh , Jaana Bagri , George Giotopoulos , Dhoyazan M A Azazi , Sarah J Horton , Cecile K Lopez , Shubha Anand , Anne-Sophie Bach , Frances Stedham , Robin Antrobus , Jack W Houghton , George S Vassiliou , Daniel Sasca , Haiyang Yun , Anthony D Whetton , Brian J P Huntly

NCAM1 (CD56) promotes leukemogenesis and confers drug resistance in AML.

Blood

Avec: Daniel Sasca , Jakub Szybinski , Andrea Schüler , Viral Shah , Jan Heidelberger , Patricia S Haehnel , Anna Dolnik , Oliver Kriege , Eva-Marie Fehr , Wolf H Gebhardt , George Reid , Claudia Scholl , Matthias Theobald , Lars Bullinger , Petra Beli , Thomas Kindler

Cohesin-dependent regulation of gene expression during differentiation is lost in cohesin-mutated myeloid malignancies.

Blood

Avec: Daniel Sasca , Haiyang Yun , George Giotopoulos , Jakub Szybinski , Theo Evan , Nicola K Wilson , Moritz Gerstung , Paolo Gallipoli , Anthony R Green , Robert Hills , Nigel Russell , Cameron S Osborne , Elli Papaemmanuil , Berthold Göttgens , Peter Campbell , Brian J P Huntly

Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression.

Nature genetics

Avec: Haiyang Yun , Nisha Narayan , Shabana Vohra , George Giotopoulos , Annalisa Mupo , Pedro Madrigal , Daniel Sasca , David Lara-Astiaso , Sarah J Horton , Shuchi Agrawal-Singh , Eshwar Meduri , Faisal Basheer , Ludovica Marando , Malgorzata Gozdecka , Oliver M Dovey , Aracely Castillo-Venzor , Xiaonan Wang , Paolo Gallipoli , Carsten Müller-Tidow , Cameron S Osborne , George S Vassiliou , Brian J P Huntly

Frequent ZNF217 mutations lead to transcriptional deregulation of interferon signal transduction via altered chromatin accessibility in B cell lymphoma.

Leukemia

Avec: Franziska Briest , Daniel Noerenberg , Cornelius Hennch , Kenichi Yoshida , Raphael Hablesreiter , Jose Nimo , Daniel Sasca , Marieluise Kirchner , Larry Mansouri , Yoshikage Inoue , Laura Wiegand , Annette M Staiger , Beatrice Casadei , Penelope Korkolopoulou , January Weiner , Armando Lopez-Guillermo , Arne Warth , Tamás Schneider , Ákos Nagy , Wolfram Klapper , Michael Hummel , George Kanellis , Ioannis Anagnostopoulos , Philipp Mertins , Lars Bullinger , Richard Rosenquist , Theodoros P Vassilakopoulos , German Ott , Seishi Ogawa , Frederik Damm

Réseau de co-auteurs

George Giotopoulos 4 collaborations

Haiyang Yun 4 collaborations

George S Vassiliou 4 collaborations

Brian J P Huntly 4 collaborations

Thomas Kindler 3 collaborations

Paolo Gallipoli 3 collaborations

Lars Bullinger 3 collaborations

Viral Shah 2 collaborations

Patricia S Haehnel 2 collaborations

Andrea Schüler 2 collaborations

Michael W M Kühn 2 collaborations

Faisal Basheer 2 collaborations

Eshwar Meduri 2 collaborations

Ludovica Marando 2 collaborations

Malgorzata Gozdecka 2 collaborations

Nigel Russell 2 collaborations

Elli Papaemmanuil 2 collaborations

Robert Hills 2 collaborations

Peter Campbell 2 collaborations

Annalisa Mupo 2 collaborations

Matthias Theobald 2 collaborations

Shuchi Agrawal-Singh 2 collaborations

Sarah J Horton 2 collaborations

Jakub Szybinski 2 collaborations

Cameron S Osborne 2 collaborations

Stefanie Jilg 1 collaboration

Juliana Schwaab 1 collaboration

Katja Sockel 1 collaboration

Carl C Crodel 1 collaboration

Valeska Brueckl 1 collaboration

Frank Stegelmann 1 collaboration

Madlen Jentzsch 1 collaboration

Margarete Moyses 1 collaboration

Stephan Fuhrmann 1 collaboration

Daniel Gundel 1 collaboration

Madlen Caduc 1 collaboration

Lino L Teichmann 1 collaboration

Florian Heidel 1 collaboration

Haifa K Al-Ali 1 collaboration

Petro E Petrides 1 collaboration

Lisa Spiecker 1 collaboration

Ines Witte 1 collaboration

Julia Mehlig 1 collaboration

Markus Meyerhöfer 1 collaboration

Victoria Petermann 1 collaboration

Piyush More 1 collaboration

Nina Cabezas-Wallscheid 1 collaboration

Sven Horke 1 collaboration

Andrea Pautz 1 collaboration

Andreas Daiber 1 collaboration

Hartmut Kleinert 1 collaboration

Borhane Guezguez 1 collaboration

Milena Mazan 1 collaboration

Ryan Asby 1 collaboration

Olivia Sheppard 1 collaboration

Monika Dudek 1 collaboration

Hartmut Döhner 1 collaboration

Richard Dillon 1 collaboration

Sylvie Freeman 1 collaboration

Oliver Ottmann 1 collaboration

Alan Burnett 1 collaboration

Margarita M Dzama 1 collaboration

Marlene Steiner 1 collaboration

Johanna Rausch 1 collaboration

Jonas Schönfeld 1 collaboration

Kerstin Kunz 1 collaboration

Martha C Taubert 1 collaboration

Gerard M McGeehan 1 collaboration

Chun-Wei Chen 1 collaboration

Patricia Hähnel 1 collaboration

Richard P Koche 1 collaboration

Scott A Armstrong 1 collaboration

Jaana Bagri 1 collaboration

Dhoyazan M A Azazi 1 collaboration

Cecile K Lopez 1 collaboration

Shubha Anand 1 collaboration

Anne-Sophie Bach 1 collaboration

Frances Stedham 1 collaboration

Robin Antrobus 1 collaboration

Jack W Houghton 1 collaboration

Anthony D Whetton 1 collaboration

Jan Heidelberger 1 collaboration

Anna Dolnik 1 collaboration

Oliver Kriege 1 collaboration

Eva-Marie Fehr 1 collaboration

Wolf H Gebhardt 1 collaboration

George Reid 1 collaboration

Claudia Scholl 1 collaboration

Petra Beli 1 collaboration

Theo Evan 1 collaboration

Nicola K Wilson 1 collaboration

Moritz Gerstung 1 collaboration

Anthony R Green 1 collaboration

Berthold Göttgens 1 collaboration

Nisha Narayan 1 collaboration

Shabana Vohra 1 collaboration

Pedro Madrigal 1 collaboration

David Lara-Astiaso 1 collaboration

Oliver M Dovey 1 collaboration

Aracely Castillo-Venzor 1 collaboration

Xiaonan Wang 1 collaboration

Carsten Müller-Tidow 1 collaboration

Franziska Briest 1 collaboration

Daniel Noerenberg 1 collaboration

Cornelius Hennch 1 collaboration

Kenichi Yoshida 1 collaboration

Raphael Hablesreiter 1 collaboration

Jose Nimo 1 collaboration

Marieluise Kirchner 1 collaboration

Larry Mansouri 1 collaboration

Yoshikage Inoue 1 collaboration

Laura Wiegand 1 collaboration

Annette M Staiger 1 collaboration

Beatrice Casadei 1 collaboration

Penelope Korkolopoulou 1 collaboration

January Weiner 1 collaboration

Armando Lopez-Guillermo 1 collaboration

Arne Warth 1 collaboration

Tamás Schneider 1 collaboration

Ákos Nagy 1 collaboration

Wolfram Klapper 1 collaboration

Michael Hummel 1 collaboration

George Kanellis 1 collaboration

Ioannis Anagnostopoulos 1 collaboration

Philipp Mertins 1 collaboration

Richard Rosenquist 1 collaboration

Theodoros P Vassilakopoulos 1 collaboration

German Ott 1 collaboration

Seishi Ogawa 1 collaboration

Frederik Damm 1 collaboration