David Needle

Affiliations

New Hampshire Veterinary Diagnostic Laboratory, College of Life Sciences and Agriculture, University of New Hampshire.

Publications (11)

The molecular mechanism of dsRNA processing by a bacterial Dicer.

Nucleic acids research

Avec: Lan Jin , He Song , Joseph E Tropea , Danielle Needle , David S Waugh , Shuo Gu , Xinhua Ji

Detection and characterization of novel luchacoviruses, genus

bioRxiv : the preprint server for biology

Avec: Ximena A Olarte-Castillo , Laura Plimpton , Holly McQueary , Yining Sun , Y Tina Yu , Sarah Cover , Amy N Richardson , Yuhan Jin , Jennifer K Grenier , Kevin J Cummings , Elizabeth Bunting , Maria Diuk-Wasser , David Needle , Krysten Schuler , Michael J Stanhope , Gary Whittaker , Laura B Goodman

Self-inhibited State of Venezuelan Equine Encephalitis Virus (VEEV) nsP2 Cysteine Protease: A Crystallographic and Molecular Dynamics Analysis.

Journal of molecular biology

Avec: Gyula Hoffka , George T Lountos , Danielle Needle , Alexander Wlodawer , David S Waugh , József Tőzsér , János András Mótyán

Population genomics of Staphylococcus pseudintermedius in companion animals in the United States.

Communications biology

Avec: Joshua T Smith , Sharlene Amador , Colin J McGonagle , David Needle , Robert Gibson , Cheryl P Andam

Characterization of a broadly specific cadaverine N-hydroxylase involved in desferrioxamine B biosynthesis in Streptomyces sviceus.

PloS one

Avec: Lesley-Ann Giddings , George T Lountos , Kang Woo Kim , Matthew Brockley , Danielle Needle , Scott Cherry , Joseph E Tropea , David S Waugh

IN SITU HYBRIDIZATION AND VIRUS CHARACTERIZATION OF SKUNK ADENOVIRUS IN NORTH AMERICAN WILDLIFE REVEALS MULTISYSTEMIC INFECTIONS IN A BROAD RANGE OF HOSTS.

Journal of wildlife diseases

Avec: Laura Bourque , Ole Nielsen , Mason Jager , Davor Ojkic , Chantale Provost , Carl A Gagnon , Betty Lockerbie , Hein Snyman , Brian Stevens , David Needle , Shotaro Nakagun , Sherri Cox , Jessica Khodadad , Megan E B Jones

Detection and characterization of novel luchacoviruses, genus

Journal of virology

Avec: Ximena A Olarte-Castillo , Laura Plimpton , Holly McQueary , Yining Sun , Y Tina Yu , Sarah Cover , Amy N Richardson , Yuhan Jin , Jennifer K Grenier , Kevin J Cummings , Elizabeth Bunting , Maria Diuk-Wasser , David Needle , Krysten Schuler , Michael J Stanhope , Gary Whittaker , Laura B Goodman

Natural disease and evolution of an Amdoparvovirus endemic in striped skunks (Mephitis mephitis).

Transboundary and emerging diseases

Avec: Charles E Alex , Marta Canuti , Maya S Schlesinger , Kenneth A Jackson , David Needle , Claire Jardine , Larissa Nituch , Laura Bourque , Andrew S Lang , Patricia A Pesavento

Phosphonic acid-containing inhibitors of tyrosyl-DNA phosphodiesterase 1.

Frontiers in chemistry

Avec: Xue Zhi Zhao , Wenjie Wang , George T Lountos , Joseph E Tropea , Danielle Needle , Yves Pommier , Terrence R Burke

Identification of a ligand binding hot spot and structural motifs replicating aspects of tyrosyl-DNA phosphodiesterase I (TDP1) phosphoryl recognition by crystallographic fragment cocktail screening.

Nucleic acids research

Avec: George T Lountos , Xue Zhi Zhao , Evgeny Kiselev , Joseph E Tropea , Danielle Needle , Yves Pommier , Terrence R Burke , David S Waugh

Small molecule microarray identifies inhibitors of tyrosyl-DNA phosphodiesterase 1 that simultaneously access the catalytic pocket and two substrate binding sites.

Chemical science

Avec: Xue Zhi Zhao , Evgeny Kiselev , George T Lountos , Wenjie Wang , Joseph E Tropea , Danielle Needle , Thomas A Hilimire , John S Schneekloth , David S Waugh , Yves Pommier , Terrence R Burke

Réseau de co-auteurs

Danielle Needle 6 collaborations

Joseph E Tropea 5 collaborations

David S Waugh 5 collaborations

George T Lountos 5 collaborations

Xue Zhi Zhao 3 collaborations

Yves Pommier 3 collaborations

Terrence R Burke 3 collaborations

Ximena A Olarte-Castillo 2 collaborations

Laura Plimpton 2 collaborations

Holly McQueary 2 collaborations

Yining Sun 2 collaborations

Y Tina Yu 2 collaborations

Sarah Cover 2 collaborations

Amy N Richardson 2 collaborations

Yuhan Jin 2 collaborations

Jennifer K Grenier 2 collaborations

Kevin J Cummings 2 collaborations

Elizabeth Bunting 2 collaborations

Maria Diuk-Wasser 2 collaborations

Krysten Schuler 2 collaborations

Michael J Stanhope 2 collaborations

Gary Whittaker 2 collaborations

Laura B Goodman 2 collaborations

Laura Bourque 2 collaborations

Wenjie Wang 2 collaborations

Evgeny Kiselev 2 collaborations

Lan Jin 1 collaboration

He Song 1 collaboration

Shuo Gu 1 collaboration

Xinhua Ji 1 collaboration

Gyula Hoffka 1 collaboration

Alexander Wlodawer 1 collaboration

József Tőzsér 1 collaboration

János András Mótyán 1 collaboration

Joshua T Smith 1 collaboration

Sharlene Amador 1 collaboration

Colin J McGonagle 1 collaboration

Robert Gibson 1 collaboration

Cheryl P Andam 1 collaboration

Lesley-Ann Giddings 1 collaboration

Kang Woo Kim 1 collaboration

Matthew Brockley 1 collaboration

Scott Cherry 1 collaboration

Ole Nielsen 1 collaboration

Mason Jager 1 collaboration

Davor Ojkic 1 collaboration

Chantale Provost 1 collaboration

Carl A Gagnon 1 collaboration

Betty Lockerbie 1 collaboration

Hein Snyman 1 collaboration

Brian Stevens 1 collaboration

Shotaro Nakagun 1 collaboration

Sherri Cox 1 collaboration

Jessica Khodadad 1 collaboration

Megan E B Jones 1 collaboration

Charles E Alex 1 collaboration

Marta Canuti 1 collaboration

Maya S Schlesinger 1 collaboration

Kenneth A Jackson 1 collaboration

Claire Jardine 1 collaboration

Larissa Nituch 1 collaboration

Andrew S Lang 1 collaboration

Patricia A Pesavento 1 collaboration

Thomas A Hilimire 1 collaboration

John S Schneekloth 1 collaboration