Derk Amsen

Affiliations

Sanquin Research, Dept of Hematopoiesis, Amsterdam, The Netherlands, and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam, The Netherlands. d.amsen@sanquin.nl.

Publications (21)

Determining the extent of maternal-foetal chimerism in cord blood.

Scientific reports

Avec: Rianne Opstelten , Manon C Slot , Neubury M Lardy , Arjan C Lankester , Arend Mulder , Frans H J Claas , Jon J van Rood , Derk Amsen

Identification of Functional HLA-A*01:01-Restricted Epstein-Barr Latent Membrane Protein 2-Specific T-Cell Receptors.

The Journal of infectious diseases

Avec: Wesley Huisman , Ilse Gille , Lieve E van der Maarel , Lois Hageman , Laura T Morton , Rob C M de Jong , Mirjam H M Heemskerk , Derk Amsen , J H Frederik Falkenburg , Inge Jedema

T cells expanded from renal cell carcinoma display tumor-specific CD137 expression but lack significant IFN-γ, TNF-α or IL-2 production.

Oncoimmunology

Avec: Saskia D van Asten , Rosa de Groot , Marleen M van Loenen , Suzanne M Castenmiller , Jeroen de Jong , Kim Monkhorst , John B A G Haanen , Derk Amsen , Axel Bex , Robbert M Spaapen , Monika C Wolkers

Humanized MISTRG as a preclinical

Frontiers in immunology

Avec: Paula Martinez-Sanz , Adrien R G Laurent , Edith Slot , Mark Hoogenboezem , Nikolina Bąbała , Robin van Bruggen , Anthony Rongvaux , Richard A Flavell , Godelieve A M Tytgat , Katka Franke , Hanke L Matlung , Taco W Kuijpers , Derk Amsen , Julien J Karrich

Ferritin heavy chain supports stability and function of the regulatory T cell lineage.

The EMBO journal

Avec: Qian Wu , Ana Rita Carlos , Faouzi Braza , Marie-Louise Bergman , Jamil Z Kitoko , Patricia Bastos-Amador , Eloy Cuadrado , Rui Martins , Bruna Sabino Oliveira , Vera C Martins , Brendon P Scicluna , Jonathan Jm Landry , Ferris E Jung , Temitope W Ademolue , Mirko Peitzsch , Jose Almeida-Santos , Jessica Thompson , Silvia Cardoso , Pedro Ventura , Manon Slot , Stamatia Rontogianni , Vanessa Ribeiro , Vital Da Silva Domingues , Inês A Cabral , Sebastian Weis , Marco Groth , Cristina Ameneiro , Miguel Fidalgo , Fudi Wang , Jocelyne Demengeot , Derk Amsen , Miguel P Soares

Blimp-1 Rather Than Hobit Drives the Formation of Tissue-Resident Memory CD8

Frontiers in immunology

Avec: Felix M Behr , Natasja A M Kragten , Thomas H Wesselink , Benjamin Nota , Rene A W van Lier , Derk Amsen , Regina Stark , Pleun Hombrink , Klaas P J M van Gisbergen

Magnitude of Off-Target Allo-HLA Reactivity by Third-Party Donor-Derived Virus-Specific T Cells Is Dictated by HLA-Restriction.

Frontiers in immunology

Avec: Wesley Huisman , Didier A T Leboux , Lieve E van der Maarel , Lois Hageman , Derk Amsen , J H Frederik Falkenburg , Inge Jedema

Public T-Cell Receptors (TCRs) Revisited by Analysis of the Magnitude of Identical and Highly-Similar TCRs in Virus-Specific T-Cell Repertoires of Healthy Individuals.

Frontiers in immunology

Avec: Wesley Huisman , Lois Hageman , Didier A T Leboux , Alexandra Khmelevskaya , Grigory A Efimov , Marthe C J Roex , Derk Amsen , J H Frederik Falkenburg , Inge Jedema

Tracking the progeny of adoptively transferred virus-specific T cells in patients posttransplant using TCR sequencing.

Blood advances

Avec: W Huisman , M C J Roex , L Hageman , E A S Koster , S A J Veld , C Hoogstraten , P van Balen , H M van Egmond , C A M van Bergen , H Einsele , L Germeroth , D Amsen , J H F Falkenburg , I Jedema

Proteomics reveals unique identities of human TGF-β-induced and thymus-derived CD4

Scientific reports

Avec: Mark Mensink , Ellen Schrama , Eloy Cuadrado , Derk Amsen , Sander de Kivit , Jannie Borst

c-Maf-dependent T

Nature immunology

Avec: Christian Neumann , Jonas Blume , Urmi Roy , Peggy P Teh , Ajithkumar Vasanthakumar , Alexander Beller , Yang Liao , Frederik Heinrich , Teresita L Arenzana , Jason A Hackney , Celine Eidenschenk , Eric J C Gálvez , Christina Stehle , Gitta A Heinz , Patrick Maschmeyer , Tom Sidwell , Yifang Hu , Derk Amsen , Chiara Romagnani , Hyun-Dong Chang , Andrey Kruglov , Mir-Farzin Mashreghi , Wei Shi , Till Strowig , Sascha Rutz , Axel Kallies , Alexander Scheffold

Single-Cell Transcriptomics Reveals Discrete Steps in Regulatory T Cell Development in the Human Thymus.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Florencia Morgana , Rianne Opstelten , Manon C Slot , Andrew M Scott , René A W van Lier , Bianca Blom , Ahmed Mahfouz , Derk Amsen

Amino acids at position 5 in the peptide/MHC binding region of a public virus-specific TCR are completely inter-changeable without loss of function.

European journal of immunology

Avec: Wesley Huisman , Melanie de Gier , Lois Hageman , Alina S Shomuradova , Didier A T Leboux , Derk Amsen , J H Frederik Falkenburg , Inge Jedema

A Bispecific γδ T-cell Engager Targeting EGFR Activates a Potent Vγ9Vδ2 T cell-Mediated Immune Response against EGFR-Expressing Tumors.

Cancer immunology research

Avec: Lisa A King , Elisa C Toffoli , Myrthe Veth , Victoria Iglesias-Guimarais , Manon C Slot , Derk Amsen , Rieneke van de Ven , Sarah Derks , Marieke F Fransen , Jurriaan B Tuynman , Thilo Riedl , Rob C Roovers , Anton E P Adang , Jurjen M Ruben , Paul W H I Parren , Tanja D de Gruijl , Hans J van der Vliet

The complexities of T-cell dysfunction in chronic lymphocytic leukemia.

Seminars in hematology

Avec: Elena Camerini , Derk Amsen , Arnon P Kater , Fleur S Peters

GPA33: A Marker to Identify Stable Human Regulatory T Cells.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Rianne Opstelten , Sander de Kivit , Manon C Slot , Maartje van den Biggelaar , Dorota Iwaszkiewicz-Grześ , Mateusz Gliwiński , Andrew M Scott , Bianca Blom , Piotr Trzonkowski , Jannie Borst , Eloy Cuadrado , Derk Amsen

Polyfunctional tumor-reactive T cells are effectively expanded from non-small cell lung cancers, and correlate with an immune-engaged T cell profile.

Oncoimmunology

Avec: Rosa De Groot , Marleen M Van Loenen , Aurélie Guislain , Benoît P Nicolet , Julian J Freen-Van Heeren , Onno J H M Verhagen , Michel M Van Den Heuvel , Jeroen De Jong , Patrick Burger , C Ellen Van Der Schoot , Robbert M Spaapen , Derk Amsen , John B A G Haanen , Kim Monkhorst , Koen J Hartemink , Monika C Wolkers

Regulatory T cell features in chronic granulomatous disease.

Clinical and experimental immunology

Avec: A van de Geer , E Cuadrado , M C Slot , R van Bruggen , D Amsen , T W Kuijpers

Separating the wheat from the chaff: Making sense of Treg heterogeneity for better adoptive cellular therapy.

Immunology letters

Avec: Rianne Opstelten , Derk Amsen

GPA33 is expressed on multiple human blood cell types and distinguishes CD4

European journal of immunology

Avec: Rianne Opstelten , Jessica S Suwandi , Manon C Slot , Florencia Morgana , Andrew M Scott , Sandra Laban , Tatjana Nikolic , Annelies W Turksma , Anna Kroeze , Carlijn Voermans , Jaap-Jan Zwaginga , Bart O Roep , Derk Amsen

Stable human regulatory T cells switch to glycolysis following TNF receptor 2 costimulation.

Nature metabolism

Avec: Sander de Kivit , Mark Mensink , Anna T Hoekstra , Ilana Berlin , Rico J E Derks , Demi Both , Muhammad A Aslam , Derk Amsen , Celia R Berkers , Jannie Borst

Réseau de co-auteurs

Rianne Opstelten 5 collaborations

Manon C Slot 5 collaborations

Wesley Huisman 4 collaborations

Lois Hageman 4 collaborations

J H Frederik Falkenburg 4 collaborations

Inge Jedema 4 collaborations

Eloy Cuadrado 3 collaborations

Didier A T Leboux 3 collaborations

Sander de Kivit 3 collaborations

Jannie Borst 3 collaborations

Andrew M Scott 3 collaborations

Lieve E van der Maarel 2 collaborations

Kim Monkhorst 2 collaborations

John B A G Haanen 2 collaborations

Robbert M Spaapen 2 collaborations

Monika C Wolkers 2 collaborations

D Amsen 2 collaborations

Mark Mensink 2 collaborations

Florencia Morgana 2 collaborations

Bianca Blom 2 collaborations

Neubury M Lardy 1 collaboration

Arjan C Lankester 1 collaboration

Arend Mulder 1 collaboration

Frans H J Claas 1 collaboration

Jon J van Rood 1 collaboration

Ilse Gille 1 collaboration

Laura T Morton 1 collaboration

Rob C M de Jong 1 collaboration

Mirjam H M Heemskerk 1 collaboration

Saskia D van Asten 1 collaboration

Rosa de Groot 1 collaboration

Marleen M van Loenen 1 collaboration

Suzanne M Castenmiller 1 collaboration

Jeroen de Jong 1 collaboration

Axel Bex 1 collaboration

Paula Martinez-Sanz 1 collaboration

Adrien R G Laurent 1 collaboration

Edith Slot 1 collaboration

Mark Hoogenboezem 1 collaboration

Nikolina Bąbała 1 collaboration

Robin van Bruggen 1 collaboration

Anthony Rongvaux 1 collaboration

Richard A Flavell 1 collaboration

Godelieve A M Tytgat 1 collaboration

Katka Franke 1 collaboration

Hanke L Matlung 1 collaboration

Taco W Kuijpers 1 collaboration

Julien J Karrich 1 collaboration

Qian Wu 1 collaboration

Ana Rita Carlos 1 collaboration

Faouzi Braza 1 collaboration

Marie-Louise Bergman 1 collaboration

Jamil Z Kitoko 1 collaboration

Patricia Bastos-Amador 1 collaboration

Rui Martins 1 collaboration

Bruna Sabino Oliveira 1 collaboration

Vera C Martins 1 collaboration

Brendon P Scicluna 1 collaboration

Jonathan Jm Landry 1 collaboration

Ferris E Jung 1 collaboration

Temitope W Ademolue 1 collaboration

Mirko Peitzsch 1 collaboration

Jose Almeida-Santos 1 collaboration

Jessica Thompson 1 collaboration

Silvia Cardoso 1 collaboration

Pedro Ventura 1 collaboration

Manon Slot 1 collaboration

Stamatia Rontogianni 1 collaboration

Vanessa Ribeiro 1 collaboration

Vital Da Silva Domingues 1 collaboration

Inês A Cabral 1 collaboration

Sebastian Weis 1 collaboration

Marco Groth 1 collaboration

Cristina Ameneiro 1 collaboration

Miguel Fidalgo 1 collaboration

Fudi Wang 1 collaboration

Jocelyne Demengeot 1 collaboration

Miguel P Soares 1 collaboration

Felix M Behr 1 collaboration

Natasja A M Kragten 1 collaboration

Thomas H Wesselink 1 collaboration

Benjamin Nota 1 collaboration

Rene A W van Lier 1 collaboration

Regina Stark 1 collaboration

Pleun Hombrink 1 collaboration

Klaas P J M van Gisbergen 1 collaboration

Alexandra Khmelevskaya 1 collaboration

Grigory A Efimov 1 collaboration

Marthe C J Roex 1 collaboration

W Huisman 1 collaboration

M C J Roex 1 collaboration

L Hageman 1 collaboration

E A S Koster 1 collaboration

S A J Veld 1 collaboration

C Hoogstraten 1 collaboration

P van Balen 1 collaboration

H M van Egmond 1 collaboration

C A M van Bergen 1 collaboration

H Einsele 1 collaboration

L Germeroth 1 collaboration

J H F Falkenburg 1 collaboration

I Jedema 1 collaboration

Ellen Schrama 1 collaboration

Christian Neumann 1 collaboration

Jonas Blume 1 collaboration

Urmi Roy 1 collaboration

Peggy P Teh 1 collaboration

Ajithkumar Vasanthakumar 1 collaboration

Alexander Beller 1 collaboration

Yang Liao 1 collaboration

Frederik Heinrich 1 collaboration

Teresita L Arenzana 1 collaboration

Jason A Hackney 1 collaboration

Celine Eidenschenk 1 collaboration

Eric J C Gálvez 1 collaboration

Christina Stehle 1 collaboration

Gitta A Heinz 1 collaboration

Patrick Maschmeyer 1 collaboration

Tom Sidwell 1 collaboration

Yifang Hu 1 collaboration

Chiara Romagnani 1 collaboration

Hyun-Dong Chang 1 collaboration

Andrey Kruglov 1 collaboration

Mir-Farzin Mashreghi 1 collaboration

Wei Shi 1 collaboration

Till Strowig 1 collaboration

Sascha Rutz 1 collaboration

Axel Kallies 1 collaboration

Alexander Scheffold 1 collaboration

René A W van Lier 1 collaboration

Ahmed Mahfouz 1 collaboration

Melanie de Gier 1 collaboration

Alina S Shomuradova 1 collaboration

Lisa A King 1 collaboration

Elisa C Toffoli 1 collaboration

Myrthe Veth 1 collaboration

Victoria Iglesias-Guimarais 1 collaboration

Rieneke van de Ven 1 collaboration

Sarah Derks 1 collaboration

Marieke F Fransen 1 collaboration

Jurriaan B Tuynman 1 collaboration

Thilo Riedl 1 collaboration

Rob C Roovers 1 collaboration

Anton E P Adang 1 collaboration

Jurjen M Ruben 1 collaboration

Paul W H I Parren 1 collaboration

Tanja D de Gruijl 1 collaboration

Hans J van der Vliet 1 collaboration

Elena Camerini 1 collaboration

Arnon P Kater 1 collaboration

Fleur S Peters 1 collaboration

Maartje van den Biggelaar 1 collaboration

Dorota Iwaszkiewicz-Grześ 1 collaboration

Mateusz Gliwiński 1 collaboration

Piotr Trzonkowski 1 collaboration

Rosa De Groot 1 collaboration

Marleen M Van Loenen 1 collaboration

Aurélie Guislain 1 collaboration

Benoît P Nicolet 1 collaboration

Julian J Freen-Van Heeren 1 collaboration

Onno J H M Verhagen 1 collaboration

Michel M Van Den Heuvel 1 collaboration

Jeroen De Jong 1 collaboration

Patrick Burger 1 collaboration

C Ellen Van Der Schoot 1 collaboration

Koen J Hartemink 1 collaboration

A van de Geer 1 collaboration

E Cuadrado 1 collaboration

M C Slot 1 collaboration

R van Bruggen 1 collaboration

T W Kuijpers 1 collaboration

Jessica S Suwandi 1 collaboration

Sandra Laban 1 collaboration

Tatjana Nikolic 1 collaboration

Annelies W Turksma 1 collaboration

Anna Kroeze 1 collaboration

Carlijn Voermans 1 collaboration

Jaap-Jan Zwaginga 1 collaboration

Bart O Roep 1 collaboration

Anna T Hoekstra 1 collaboration

Ilana Berlin 1 collaboration

Rico J E Derks 1 collaboration

Demi Both 1 collaboration

Muhammad A Aslam 1 collaboration

Celia R Berkers 1 collaboration