Dirk Garmann

Affiliations

Clinical Pharmacometrics, Bayer AG, Wuppertal, Germany.

Publications (22)

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the prevention of venous thromboembolism.

Journal of thrombosis and thrombolysis

Avec: Isabel Reinecke , Alexander Solms , Stefan Willmann , Theodore E Spiro , Gary Peters , Jeffrey I Weitz , Wolfgang Mueck , Dirk Garmann , Stephan Schmidt , Liping Zhang , Keith A A Fox , Scott D Berkowitz

Influence of model-predicted rivaroxaban exposure and patient characteristics on efficacy and safety outcomes in patients with acute coronary syndrome.

Therapeutic advances in cardiovascular disease

Avec: Liping Zhang , Xiaoyu Yan , Partha Nandy , Stefan Willmann , Keith A A Fox , Scott D Berkowitz , Amarnath Sharma , Anne Hermanowski-Vosatka , Stephan Schmidt , Jeffrey I Weitz , Dirk Garmann , Gary Peters

Relationship between factor VIII activity, bleeds and individual characteristics in severe hemophilia A patients.

Haematologica

Avec: João A Abrantes , Alexander Solms , Dirk Garmann , Elisabet I Nielsen , Siv Jönsson , Mats O Karlsson

Population Pharmacokinetic and Exposure-Response Analysis of Finerenone: Insights Based on Phase IIb Data and Simulations to Support Dose Selection for Pivotal Trials in Type 2 Diabetes with Chronic Kidney Disease.

Clinical pharmacokinetics

Avec: Nelleke Snelder , Roland Heinig , Henk-Jan Drenth , Amer Joseph , Peter Kolkhof , Jörg Lippert , Dirk Garmann , Bart Ploeger , Thomas Eissing

Finerenone Dose-Exposure-Serum Potassium Response Analysis of FIDELIO-DKD Phase III: The Role of Dosing, Titration, and Inclusion Criteria.

Clinical pharmacokinetics

Avec: Sebastiaan Camiel Goulooze , Nelleke Snelder , Andreas Seelmann , Andrea Horvat-Broecker , Meike Brinker , Amer Joseph , Dirk Garmann , Joerg Lippert , Thomas Eissing

Model-informed approach to support pediatric dosing for the pan-PI3K inhibitor copanlisib in children and adolescents with relapsed/refractory solid tumors.

Clinical and translational science

Avec: Peter N Morcos , Jan Schlender , Rolf Burghaus , Jonathan Moss , Adam Lloyd , Barrett H Childs , Margaret E Macy , Joel M Reid , John Chung , Dirk Garmann

NT-proBNP Qualifies as a Surrogate for Clinical End Points in Heart Failure.

Clinical pharmacology and therapeutics

Avec: Walter Schmitt , Hauke Rühs , Rolf Burghaus , Christian Diedrich , Sulav Duwal , Thomas Eissing , Dirk Garmann , Michaela Meyer , Bart Ploeger , Jörg Lippert

Enhancing the Quality of Rivaroxaban Exposure Estimates Using Prothrombin Time in the Absence of Pharmacokinetic Sampling.

CPT: pharmacometrics & systems pharmacology

Avec: Alexander Solms , Matthias Frede , Scott D Berkowitz , Anne Hermanowski-Vosatka , Dagmar Kubitza , Wolfgang Mueck , Theodore E Spiro , Stefan Willmann , Xiaoyu Yan , Liping Zhang , Dirk Garmann

Favorable Pharmacokinetic Characteristics of Extended-Half-Life Recombinant Factor VIII BAY 94-9027 Enable Robust Individual Profiling Using a Population Pharmacokinetic Approach.

Clinical pharmacokinetics

Avec: Alexander Solms , Alfonso Iorio , Maurice J Ahsman , Peter Vis , Anita Shah , Erik Berntorp , Dirk Garmann

Finerenone Dose-Exposure-Response for the Primary Kidney Outcome in FIDELIO-DKD Phase III: Population Pharmacokinetic and Time-to-Event Analysis.

Clinical pharmacokinetics

Avec: Paul van den Berg , Martijn Ruppert , Emir Mesic , Nelleke Snelder , Andreas Seelmann , Roland Heinig , Amer Joseph , Dirk Garmann , Joerg Lippert , Thomas Eissing

Population Pharmacokinetics of Nifurtimox in Adult and Pediatric Patients With Chagas Disease.

Journal of clinical pharmacology

Avec: Ibrahim Ince , Klaas Prins , Stefan Willmann , Gabriele Sutter , Eva Hanze , Farrah Sadre-Marandi , Heino Stass , Dirk Garmann

Assessing QTc Effects of Vericiguat Using Two Different Concentration-QTc Modeling Approaches.

Clinical pharmacokinetics

Avec: Hauke Ruehs , Alexander Solms , Matthias Frei , Corina Becker , Maria E Trujillo , Dirk Garmann , Michaela Meyer

Bayesian Forecasting Utilizing Bleeding Information to Support Dose Individualization of Factor VIII.

CPT: pharmacometrics & systems pharmacology

Avec: João A Abrantes , Alexander Solms , Dirk Garmann , Elisabet I Nielsen , Siv Jönsson , Mats O Karlsson

Evaluation of covariate effects in item response theory models.

CPT: pharmacometrics & systems pharmacology

Avec: Gustaf J Wellhagen , Ashraf Yassen , Dirk Garmann , Astrid Bröker , Alexander Solms , Yang Zhang , Maria C Kjellsson , Mats O Karlsson

Model-Based Benefit/Risk Analysis for the Copanlisib Intermittent Dosing Regimen.

Clinical pharmacology and therapeutics

Avec: Peter N Morcos , Jonathan Moss , Josh Veasy , Florian Hiemeyer , Barrett H Childs , Dirk Garmann

Item response theory analysis of daytime sleepiness as a symptom of obstructive sleep apnea.

CPT: pharmacometrics & systems pharmacology

Avec: Gustaf J Wellhagen , Mats O Karlsson , Maria C Kjellsson , Dirk Garmann , Astrid Bröker , Yang Zhang , Mika Nokela , Gerrit Weimann , Ashraf Yassen

Project DECIDE, part 1: increasing the amount of valid advance directives in people with Alzheimer's disease by offering advance care planning-a prospective double-arm intervention study.

BMC medical ethics

Avec: Stefanie Baisch , Christina Abele , Anna Theile-Schürholz , Irene Schmidtmann , Frank Oswald , Tarik Karakaya , Tanja Müller , Janina Florack , Daniel Garmann , Jonas Karneboge , Gregor Lindl , Nathalie Pfeiffer , Aoife Poth , Bogdan Alin Caba , Martin Grond , Ingmar Hornke , David Prvulovic , Andreas Reif , Heiko Ullrich , Julia Haberstroh

Associations between model-predicted rivaroxaban exposure and patient characteristics and efficacy and safety outcomes in the treatment of venous thromboembolism.

Journal of thrombosis and thrombolysis

Avec: Alexander Solms , Stefan Willmann , Isabel Reinecke , Theodore E Spiro , Gary Peters , Jeffrey I Weitz , Wolfgang Mueck , Dirk Garmann , Stephan Schmidt , Liping Zhang , Keith A A Fox , Scott D Berkowitz

Population Pharmacokinetics and Pharmacodynamics of Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction.

Clinical pharmacokinetics

Avec: Hauke Ruehs , Dagmar Klein , Matthias Frei , Joachim Grevel , Rupert Austin , Corina Becker , Lothar Roessig , Burkert Pieske , Dirk Garmann , Michaela Meyer

Pharmacokinetics and pharmacodynamics of finerenone in patients with chronic kidney disease and type 2 diabetes: Insights based on FIGARO-DKD and FIDELIO-DKD.

Diabetes, obesity & metabolism

Avec: Thomas Eissing , Sebastiaan Camiel Goulooze , Paul van den Berg , Martijn van Noort , Martijn Ruppert , Nelleke Snelder , Dirk Garmann , Joerg Lippert , Roland Heinig , Meike Brinker , Hiddo J L Heerspink

Copanlisib population pharmacokinetics from phase I-III studies and exposure-response relationships in combination with rituximab.

CPT: pharmacometrics & systems pharmacology

Avec: Peter N Morcos , Jonathan Moss , Rupert Austin , Florian Hiemeyer , Pier Luigi Zinzani , Vita Beckert , Lidia Mongay Soler , Barrett H Childs , Dirk Garmann

Project DECIDE, part II: decision-making places for people with dementia in Alzheimer's disease: supporting advance decision-making by improving person-environment fit.

BMC medical ethics

Avec: Janina Florack , Christina Abele , Stefanie Baisch , Simon Forstmeier , Daniel Garmann , Martin Grond , Ingmar Hornke , Tarik Karakaya , Jonas Karneboge , Boris Knopf , Gregor Lindl , Tanja Müller , Frank Oswald , Nathalie Pfeiffer , David Prvulovic , Aoife Poth , Andreas Reif , Irene Schmidtmann , Anna Theile-Schürholz , Heiko Ullrich , Julia Haberstroh

Réseau de co-auteurs

Alexander Solms 8 collaborations

Stefan Willmann 5 collaborations

Thomas Eissing 5 collaborations

Liping Zhang 4 collaborations

Scott D Berkowitz 4 collaborations

Mats O Karlsson 4 collaborations

Nelleke Snelder 4 collaborations

Theodore E Spiro 3 collaborations

Gary Peters 3 collaborations

Jeffrey I Weitz 3 collaborations

Wolfgang Mueck 3 collaborations

Stephan Schmidt 3 collaborations

Keith A A Fox 3 collaborations

Roland Heinig 3 collaborations

Amer Joseph 3 collaborations

Joerg Lippert 3 collaborations

Peter N Morcos 3 collaborations

Jonathan Moss 3 collaborations

Barrett H Childs 3 collaborations

Michaela Meyer 3 collaborations

Isabel Reinecke 2 collaborations

Xiaoyu Yan 2 collaborations

Anne Hermanowski-Vosatka 2 collaborations

João A Abrantes 2 collaborations

Elisabet I Nielsen 2 collaborations

Siv Jönsson 2 collaborations

Jörg Lippert 2 collaborations

Bart Ploeger 2 collaborations

Sebastiaan Camiel Goulooze 2 collaborations

Andreas Seelmann 2 collaborations

Meike Brinker 2 collaborations

Rolf Burghaus 2 collaborations

Paul van den Berg 2 collaborations

Martijn Ruppert 2 collaborations

Hauke Ruehs 2 collaborations

Matthias Frei 2 collaborations

Corina Becker 2 collaborations

Gustaf J Wellhagen 2 collaborations

Ashraf Yassen 2 collaborations

Astrid Bröker 2 collaborations

Yang Zhang 2 collaborations

Maria C Kjellsson 2 collaborations

Florian Hiemeyer 2 collaborations

Stefanie Baisch 2 collaborations

Christina Abele 2 collaborations

Anna Theile-Schürholz 2 collaborations

Irene Schmidtmann 2 collaborations

Frank Oswald 2 collaborations

Tarik Karakaya 2 collaborations

Tanja Müller 2 collaborations

Janina Florack 2 collaborations

Daniel Garmann 2 collaborations

Jonas Karneboge 2 collaborations

Gregor Lindl 2 collaborations

Nathalie Pfeiffer 2 collaborations

Aoife Poth 2 collaborations

Martin Grond 2 collaborations

Ingmar Hornke 2 collaborations

David Prvulovic 2 collaborations

Andreas Reif 2 collaborations

Heiko Ullrich 2 collaborations

Julia Haberstroh 2 collaborations

Rupert Austin 2 collaborations

Partha Nandy 1 collaboration

Amarnath Sharma 1 collaboration

Henk-Jan Drenth 1 collaboration

Peter Kolkhof 1 collaboration

Andrea Horvat-Broecker 1 collaboration

Jan Schlender 1 collaboration

Adam Lloyd 1 collaboration

Margaret E Macy 1 collaboration

Joel M Reid 1 collaboration

John Chung 1 collaboration

Walter Schmitt 1 collaboration

Hauke Rühs 1 collaboration

Christian Diedrich 1 collaboration

Sulav Duwal 1 collaboration

Matthias Frede 1 collaboration

Dagmar Kubitza 1 collaboration

Alfonso Iorio 1 collaboration

Maurice J Ahsman 1 collaboration

Peter Vis 1 collaboration

Anita Shah 1 collaboration

Erik Berntorp 1 collaboration

Emir Mesic 1 collaboration

Ibrahim Ince 1 collaboration

Klaas Prins 1 collaboration

Gabriele Sutter 1 collaboration

Eva Hanze 1 collaboration

Farrah Sadre-Marandi 1 collaboration

Heino Stass 1 collaboration

Maria E Trujillo 1 collaboration

Josh Veasy 1 collaboration

Mika Nokela 1 collaboration

Gerrit Weimann 1 collaboration

Bogdan Alin Caba 1 collaboration

Dagmar Klein 1 collaboration

Joachim Grevel 1 collaboration

Lothar Roessig 1 collaboration

Burkert Pieske 1 collaboration

Martijn van Noort 1 collaboration

Hiddo J L Heerspink 1 collaboration

Pier Luigi Zinzani 1 collaboration

Vita Beckert 1 collaboration

Lidia Mongay Soler 1 collaboration

Simon Forstmeier 1 collaboration

Boris Knopf 1 collaboration