E M Rego

Publications (9)

NT157 has antineoplastic effects and inhibits IRS1/2 and STAT3/5 in JAK2

Signal transduction and targeted therapy

Avec: Bruna Alves Fenerich , Jaqueline Cristina Fernandes , Ana Paula Nunes Rodrigues Alves , Juan Luiz Coelho-Silva , Renata Scopim-Ribeiro , Priscila Santos Scheucher , Christopher A Eide , Cristina E Tognon , Brian J Druker , Eduardo Magalhães Rego , João Agostinho Machado-Neto , Fabiola Traina

Integrating clinical features with genetic factors enhances survival prediction for adults with acute myeloid leukemia.

Blood advances

Avec: Douglas R A Silveira , Lynn Quek , Itamar S Santos , Anna Corby , Juan L Coelho-Silva , Diego A Pereira-Martins , Grant Vallance , Benjamin Brown , Luciana Nardinelli , Wellington F Silva , Elvira D R P Velloso , Antonio R Lucena-Araujo , Fabiola Traina , Andy Peniket , Paresh Vyas , Eduardo M Rego , Israel Bendit , Vanderson Rocha

Autophagy inhibition potentiates ruxolitinib-induced apoptosis in JAK2

Investigational new drugs

Avec: João Agostinho Machado-Neto , Juan Luiz Coelho-Silva , Fábio Pires de Souza Santos , Priscila Santos Scheucher , Paulo Vidal Campregher , Nelson Hamerschlak , Eduardo Magalhães Rego , Fabiola Traina

IGF1R/IRS1 targeting has cytotoxic activity and inhibits PI3K/AKT/mTOR and MAPK signaling in acute lymphoblastic leukemia cells.

Cancer letters

Avec: Ana Paula Nunes Rodrigues Alves , Jaqueline Cristina Fernandes , Bruna Alves Fenerich , Juan Luiz Coelho-Silva , Priscila Santos Scheucher , Belinda Pinto Simões , Eduardo Magalhães Rego , Anne J Ridley , João Agostinho Machado-Neto , Fabiola Traina

Outcomes and second neoplasms in hairy cell leukemia: A retrospective cohort.

Leukemia research

Avec: Wellington F da Silva , Abel Costa Neto , Lidiane Inês da Rosa , Isabela Assis de Siqueira , Guilherme Duffles Amarante , Elvira D R P Velloso , Eduardo Magalhães Rego , Vanderson Rocha , Valeria Buccheri

The Glycolytic Gatekeeper PDK1 defines different metabolic states between genetically distinct subtypes of human acute myeloid leukemia.

Nature communications

Avec: Ayşegül Erdem , Silvia Marin , Diego A Pereira-Martins , Roldán Cortés , Alan Cunningham , Maurien G Pruis , Bauke de Boer , Fiona A J van den Heuvel , Marjan Geugien , Albertus T J Wierenga , Annet Z Brouwers-Vos , Eduardo M Rego , Gerwin Huls , Marta Cascante , Jan Jacob Schuringa

Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability.

Nature communications

Avec: Ayşegül Erdem , Silvia Marin , Diego A Pereira-Martins , Marjan Geugien , Alan Cunningham , Maurien G Pruis , Isabel Weinhäuser , Albert Gerding , Barbara M Bakker , Albertus T J Wierenga , Eduardo M Rego , Gerwin Huls , Marta Cascante , Jan Jacob Schuringa

Clinical significance of mitochondrial DNA content in acute promyelocytic leukaemia.

British journal of haematology

Avec: Diego A Pereira-Martins , Juan L Coelho-Silva , Isabel Weinhäuser , Pedro L Franca-Neto , Douglas R Silveira , César Ortiz , Amanda Moreira-Aguiar , Marinus M Lima , Luisa C Koury , Raul A de Melo , Ana B Glória , Evandro M Fagundes , Bruno K Lino , Katia Pagnano , Rosane Bittencourt , Elenaide Nunes , Fabiola Traina , Lorena Figueiredo-Pontes , Armand Keating , Martin S Tallman , Raul C Ribeiro , Richard Dilon , Arnold Ganser , Miguel A Sanz , Nancy Berliner , Peter Valk , Bob Löwenberg , Tiziana Ottone , Nelida I Noguera , Maria T Voso , Francesca Paoloni , Paola Fazi , Emanuele Ammatuna , Gerwin Huls , Jan Jacob Schuringa , Eduardo M Rego , Antonio R Lucena-Araujo

Thiostrepton induces cell death of acute myeloid leukemia blasts and the associated macrophage population.

Haematologica

Avec: Isabel Weinhäuser , Diego A Pereira-Martins , Jacobien R Hilberink , Annet Brouwers-Vos , Eduardo M Rego , Gerwin Huls , Jan Jacob Schuringa

Réseau de co-auteurs

Fabiola Traina 5 collaborations

Diego A Pereira-Martins 5 collaborations

Eduardo M Rego 5 collaborations

Eduardo Magalhães Rego 4 collaborations

Gerwin Huls 4 collaborations

Jan Jacob Schuringa 4 collaborations

Juan Luiz Coelho-Silva 3 collaborations

Priscila Santos Scheucher 3 collaborations

João Agostinho Machado-Neto 3 collaborations

Isabel Weinhäuser 3 collaborations

Bruna Alves Fenerich 2 collaborations

Jaqueline Cristina Fernandes 2 collaborations

Ana Paula Nunes Rodrigues Alves 2 collaborations

Juan L Coelho-Silva 2 collaborations

Elvira D R P Velloso 2 collaborations

Antonio R Lucena-Araujo 2 collaborations

Vanderson Rocha 2 collaborations

Ayşegül Erdem 2 collaborations

Silvia Marin 2 collaborations

Alan Cunningham 2 collaborations

Maurien G Pruis 2 collaborations

Marjan Geugien 2 collaborations

Albertus T J Wierenga 2 collaborations

Marta Cascante 2 collaborations

Renata Scopim-Ribeiro 1 collaboration

Christopher A Eide 1 collaboration

Cristina E Tognon 1 collaboration

Brian J Druker 1 collaboration

Douglas R A Silveira 1 collaboration

Lynn Quek 1 collaboration

Itamar S Santos 1 collaboration

Anna Corby 1 collaboration

Grant Vallance 1 collaboration

Benjamin Brown 1 collaboration

Luciana Nardinelli 1 collaboration

Wellington F Silva 1 collaboration

Andy Peniket 1 collaboration

Paresh Vyas 1 collaboration

Israel Bendit 1 collaboration

Fábio Pires de Souza Santos 1 collaboration

Paulo Vidal Campregher 1 collaboration

Nelson Hamerschlak 1 collaboration

Belinda Pinto Simões 1 collaboration

Anne J Ridley 1 collaboration

Wellington F da Silva 1 collaboration

Abel Costa Neto 1 collaboration

Lidiane Inês da Rosa 1 collaboration

Isabela Assis de Siqueira 1 collaboration

Guilherme Duffles Amarante 1 collaboration

Valeria Buccheri 1 collaboration

Roldán Cortés 1 collaboration

Bauke de Boer 1 collaboration

Fiona A J van den Heuvel 1 collaboration

Annet Z Brouwers-Vos 1 collaboration

Albert Gerding 1 collaboration

Barbara M Bakker 1 collaboration

Pedro L Franca-Neto 1 collaboration

Douglas R Silveira 1 collaboration

César Ortiz 1 collaboration

Amanda Moreira-Aguiar 1 collaboration

Marinus M Lima 1 collaboration

Luisa C Koury 1 collaboration

Raul A de Melo 1 collaboration

Ana B Glória 1 collaboration

Evandro M Fagundes 1 collaboration

Bruno K Lino 1 collaboration

Katia Pagnano 1 collaboration

Rosane Bittencourt 1 collaboration

Elenaide Nunes 1 collaboration

Lorena Figueiredo-Pontes 1 collaboration

Armand Keating 1 collaboration

Martin S Tallman 1 collaboration

Raul C Ribeiro 1 collaboration

Richard Dilon 1 collaboration

Arnold Ganser 1 collaboration

Miguel A Sanz 1 collaboration

Nancy Berliner 1 collaboration

Peter Valk 1 collaboration

Bob Löwenberg 1 collaboration

Tiziana Ottone 1 collaboration

Nelida I Noguera 1 collaboration

Maria T Voso 1 collaboration

Francesca Paoloni 1 collaboration

Paola Fazi 1 collaboration

Emanuele Ammatuna 1 collaboration

Jacobien R Hilberink 1 collaboration

Annet Brouwers-Vos 1 collaboration