Filipa Marcelo

Affiliations

Departamento de Química, Faculdade de Ciências e Tecnologia, UCIBIO, REQUIMTE, 2829-516 Caparica, Portugal.

Publications (15)

Identification of a secondary binding site in human macrophage galactose-type lectin by microarray studies: Implications for the molecular recognition of its ligands.

The Journal of biological chemistry

Avec: Filipa Marcelo , Nitin Supekar , Francisco Corzana , Joost C van der Horst , Ilona M Vuist , David Live , Geert-Jan P H Boons , David F Smith , Sandra J van Vliet

Structural Insights into the Molecular Recognition Mechanism of the Cancer and Pathogenic Epitope, LacdiNAc by Immune-Related Lectins.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Carlos D L Lima , Helena Coelho , Ana Gimeno , Filipa Trovão , Ana Diniz , Jorge S Dias , Jesús Jiménez-Barbero , Francisco Corzana , Ana Luísa Carvalho , Eurico J Cabrita , Filipa Marcelo

Structural characterization of an unprecedented lectin-like antitumoral anti-MUC1 antibody.

Chemical communications (Cambridge, England)

Avec: Javier Macías-León , Iris A Bermejo , Alicia Asín , Ana García-García , Ismael Compañón , Ester Jiménez-Moreno , Helena Coelho , Vincenzo Mangini , Inês S Albuquerque , Filipa Marcelo , Juan L Asensio , Gonçalo J L Bernardes , Hiren J Joshi , Roberto Fiammengo , Ola Blixt , Ramón Hurtado-Guerrero , Francisco Corzana

Unraveling Molecular Recognition of Glycan Ligands by Siglec-9 via NMR Spectroscopy and Molecular Dynamics Modeling.

ACS chemical biology

Avec: Unai Atxabal , Corwin Nycholat , Johannes M Pröpster , Andrea Fernández , Iker Oyenarte , Maria Pia Lenza , Antonio Franconetti , Cátia O Soares , Helena Coelho , Filipa Marcelo , Mario Schubert , James C Paulson , Jesús Jiménez-Barbero , June Ereño-Orbea

The pleiotropic CLEC10A: implications for harnessing this receptor in the tumor microenvironment.

Expert opinion on therapeutic targets

Avec: Nadia L van der Meijs , Maria Alejandra Travecedo , Filipa Marcelo , Sandra J van Vliet

The role of sialoglycans in modulating dendritic cell function and tumour immunity.

Seminars in immunology

Avec: Zélia Silva , Cátia O Soares , Mariana Barbosa , Angelina S Palma , Filipa Marcelo , Paula A Videira

The Plasticity of the Carbohydrate Recognition Domain Dictates the Exquisite Mechanism of Binding of Human Macrophage Galactose-Type Lectin.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Ana Diniz , Helena Coelho , Jorge S Dias , Sandra J van Vliet , Jesús Jiménez-Barbero , Francisco Corzana , Eurico J Cabrita , Filipa Marcelo

Structural Characterization of N-Linked Glycans in the Receptor Binding Domain of the SARS-CoV-2 Spike Protein and their Interactions with Human Lectins.

Angewandte Chemie (International ed. in English)

Avec: Maria Pia Lenza , Iker Oyenarte , Tammo Diercks , Jon Imanol Quintana , Ana Gimeno , Helena Coelho , Ana Diniz , Francesca Peccati , Sandra Delgado , Alexandre Bosch , Mikel Valle , Oscar Millet , Nicola G A Abrescia , Asís Palazón , Filipa Marcelo , Gonzalo Jiménez-Osés , Jesús Jiménez-Barbero , Ana Ardá , June Ereño-Orbea

Crystal Structure of the Carbohydrate Recognition Domain of the Human Macrophage Galactose C-Type Lectin Bound to GalNAc and the Tumor-Associated Tn Antigen.

Biochemistry

Avec: Adele Gabba , Agnieszka Bogucka , John G Luz , Ana Diniz , Helena Coelho , Francisco Corzana , Francisco Javier Cañada , Filipa Marcelo , Paul V Murphy , Gabriel Birrane

Glucosylpolyphenols as Inhibitors of Aβ-Induced Fyn Kinase Activation and Tau Phosphorylation: Synthesis, Membrane Permeability, and Exploratory Target Assessment within the Scope of Type 2 Diabetes and Alzheimer's Disease.

Journal of medicinal chemistry

Avec: Ana M de Matos , M Teresa Blázquez-Sánchez , Andreia Bento-Oliveira , Rodrigo F M de Almeida , Rafael Nunes , Pedro E M Lopes , Miguel Machuqueiro , Joana S Cristóvão , Cláudio M Gomes , Cleide S Souza , Imane G El Idrissi , Nicola A Colabufo , Ana Diniz , Filipa Marcelo , M Conceição Oliveira , Óscar López , José G Fernandez-Bolaños , Philipp Dätwyler , Beat Ernst , Ke Ning , Claire Garwood , Beining Chen , Amélia P Rauter

Structural insights into Siglec-15 reveal glycosylation dependency for its interaction with T cells through integrin CD11b.

Nature communications

Avec: Maria Pia Lenza , Leire Egia-Mendikute , Asier Antoñana-Vildosola , Cátia O Soares , Helena Coelho , Francisco Corzana , Alexandre Bosch , Prodhi Manisha , Jon Imanol Quintana , Iker Oyenarte , Luca Unione , María Jesús Moure , Mikel Azkargorta , Unai Atxabal , Klaudia Sobczak , Felix Elortza , James D Sutherland , Rosa Barrio , Filipa Marcelo , Jesús Jiménez-Barbero , Asis Palazon , June Ereño-Orbea

Molecular basis for the preferential recognition of β1,3-1,4-glucans by the family 11 carbohydrate-binding module from Clostridium thermocellum.

The FEBS journal

Avec: Diana O Ribeiro , Aldino Viegas , Virgínia M R Pires , João Medeiros-Silva , Pedro Bule , Wengang Chai , Filipa Marcelo , Carlos M G A Fontes , Eurico J Cabrita , Angelina S Palma , Ana Luísa Carvalho

Molecular Recognition Insights of Sialic Acid Glycans by Distinct Receptors Unveiled by NMR and Molecular Modeling.

Frontiers in molecular biosciences

Avec: Cátia Oliveira Soares , Ana Sofia Grosso , June Ereño-Orbea , Helena Coelho , Filipa Marcelo

Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case.

Journal of medicinal chemistry

Avec: Cristiano Mota , Ana Diniz , Catarina Coelho , Teresa Santos-Silva , Mariam Esmaeeli , Silke Leimkühler , Eurico J Cabrita , Filipa Marcelo , Maria João Romão

Structures of the Inhibitory Receptor Siglec-8 in Complex with a High-Affinity Sialoside Analogue and a Therapeutic Antibody.

JACS Au

Avec: Maria Pia Lenza , Unai Atxabal , Corwin Nycholat , Iker Oyenarte , Antonio Franconetti , Jon Imanol Quintana , Sandra Delgado , Reyes Núñez-Franco , Carmen Teresa Garnica Marroquín , Helena Coelho , Luca Unione , Gonzalo Jiménez-Oses , Filipa Marcelo , Mario Schubert , James C Paulson , Jesús Jiménez-Barbero , June Ereño-Orbea

Réseau de co-auteurs

Helena Coelho 9 collaborations

Francisco Corzana 6 collaborations

Ana Diniz 6 collaborations

Jesús Jiménez-Barbero 6 collaborations

June Ereño-Orbea 5 collaborations

Eurico J Cabrita 4 collaborations

Iker Oyenarte 4 collaborations

Maria Pia Lenza 4 collaborations

Sandra J van Vliet 3 collaborations

Unai Atxabal 3 collaborations

Cátia O Soares 3 collaborations

Jon Imanol Quintana 3 collaborations

Ana Gimeno 2 collaborations

Jorge S Dias 2 collaborations

Ana Luísa Carvalho 2 collaborations

Corwin Nycholat 2 collaborations

Antonio Franconetti 2 collaborations

Mario Schubert 2 collaborations

James C Paulson 2 collaborations

Angelina S Palma 2 collaborations

Sandra Delgado 2 collaborations

Alexandre Bosch 2 collaborations

Luca Unione 2 collaborations

Nitin Supekar 1 collaboration

Joost C van der Horst 1 collaboration

Ilona M Vuist 1 collaboration

David Live 1 collaboration

Geert-Jan P H Boons 1 collaboration

David F Smith 1 collaboration

Carlos D L Lima 1 collaboration

Filipa Trovão 1 collaboration

Javier Macías-León 1 collaboration

Iris A Bermejo 1 collaboration

Alicia Asín 1 collaboration

Ana García-García 1 collaboration

Ismael Compañón 1 collaboration

Ester Jiménez-Moreno 1 collaboration

Vincenzo Mangini 1 collaboration

Inês S Albuquerque 1 collaboration

Juan L Asensio 1 collaboration

Gonçalo J L Bernardes 1 collaboration

Hiren J Joshi 1 collaboration

Roberto Fiammengo 1 collaboration

Ola Blixt 1 collaboration

Ramón Hurtado-Guerrero 1 collaboration

Johannes M Pröpster 1 collaboration

Andrea Fernández 1 collaboration

Nadia L van der Meijs 1 collaboration

Maria Alejandra Travecedo 1 collaboration

Zélia Silva 1 collaboration

Mariana Barbosa 1 collaboration

Paula A Videira 1 collaboration

Tammo Diercks 1 collaboration

Francesca Peccati 1 collaboration

Mikel Valle 1 collaboration

Oscar Millet 1 collaboration

Nicola G A Abrescia 1 collaboration

Asís Palazón 1 collaboration

Gonzalo Jiménez-Osés 1 collaboration

Ana Ardá 1 collaboration

Adele Gabba 1 collaboration

Agnieszka Bogucka 1 collaboration

John G Luz 1 collaboration

Francisco Javier Cañada 1 collaboration

Paul V Murphy 1 collaboration

Gabriel Birrane 1 collaboration

Ana M de Matos 1 collaboration

M Teresa Blázquez-Sánchez 1 collaboration

Andreia Bento-Oliveira 1 collaboration

Rodrigo F M de Almeida 1 collaboration

Rafael Nunes 1 collaboration

Pedro E M Lopes 1 collaboration

Miguel Machuqueiro 1 collaboration

Joana S Cristóvão 1 collaboration

Cláudio M Gomes 1 collaboration

Cleide S Souza 1 collaboration

Imane G El Idrissi 1 collaboration

Nicola A Colabufo 1 collaboration

M Conceição Oliveira 1 collaboration

Óscar López 1 collaboration

José G Fernandez-Bolaños 1 collaboration

Philipp Dätwyler 1 collaboration

Beat Ernst 1 collaboration

Ke Ning 1 collaboration

Claire Garwood 1 collaboration

Beining Chen 1 collaboration

Amélia P Rauter 1 collaboration

Leire Egia-Mendikute 1 collaboration

Asier Antoñana-Vildosola 1 collaboration

Prodhi Manisha 1 collaboration

María Jesús Moure 1 collaboration

Mikel Azkargorta 1 collaboration

Klaudia Sobczak 1 collaboration

Felix Elortza 1 collaboration

James D Sutherland 1 collaboration

Rosa Barrio 1 collaboration

Asis Palazon 1 collaboration

Diana O Ribeiro 1 collaboration

Aldino Viegas 1 collaboration

Virgínia M R Pires 1 collaboration

João Medeiros-Silva 1 collaboration

Pedro Bule 1 collaboration

Wengang Chai 1 collaboration

Carlos M G A Fontes 1 collaboration

Cátia Oliveira Soares 1 collaboration

Ana Sofia Grosso 1 collaboration

Cristiano Mota 1 collaboration

Catarina Coelho 1 collaboration

Teresa Santos-Silva 1 collaboration

Mariam Esmaeeli 1 collaboration

Silke Leimkühler 1 collaboration

Maria João Romão 1 collaboration

Reyes Núñez-Franco 1 collaboration

Carmen Teresa Garnica Marroquín 1 collaboration

Gonzalo Jiménez-Oses 1 collaboration