Filippo Spriano

Affiliations

Institute of Oncology Research, Faculty of Biomedical Sciences, Università della Svizzera Italiana (USI), Bellinzona, Switzerland.

ORCID: 0000-0002-8615-1568

Publications (14)

Study of the antilymphoma activity of pracinostat reveals different sensitivities of DLBCL cells to HDAC inhibitors.

Blood advances

Avec: Afua Adjeiwaa Mensah , Filippo Spriano , Giulio Sartori , Valdemar Priebe , Luciano Cascione , Eugenio Gaudio , Chiara Tarantelli , Elisa Civanelli , Luca Aresu , Andrea Rinaldi , Giovanna Damia , Emanuela Lovati , Emanuele Zucca , Anastasios Stathis , Claudio Pietra , Francesco Bertoni

The Novel TORC1/2 Kinase Inhibitor PQR620 Has Anti-Tumor Activity in Lymphomas as a Single Agent and in Combination with Venetoclax.

Cancers

Avec: Chiara Tarantelli , Eugenio Gaudio , Petra Hillmann , Filippo Spriano , Giulio Sartori , Luca Aresu , Luciano Cascione , Denise Rageot , Ivo Kwee , Florent Beaufils , Emanuele Zucca , Anastasios Stathis , Matthias P Wymann , Vladimir Cmiljanovic , Doriano Fabbro , Francesco Bertoni

DNA Damage Response Inhibitor Combinations Exert Synergistic Antitumor Activity in Aggressive B-Cell Lymphomas.

Molecular cancer therapeutics

Avec: Valentina Restelli , Monica Lupi , Rosaria Chilà , Micaela Vagni , Chiara Tarantelli , Filippo Spriano , Eugenio Gaudio , Francesco Bertoni , Giovanna Damia , Laura Carrassa

Characterization of GECPAR, a noncoding RNA that regulates the transcriptional program of diffuse large B-cell lymphoma.

Haematologica

Avec: Sara Napoli , Luciano Cascione , Andrea Rinaldi , Filippo Spriano , Francesca Guidetti , Fangwen Zhang , Maria Teresa Cacciapuoti , Afua Adjeiwaa Mensah , Giulio Sartori , Nicolas Munz , Mattia Forcato , Silvio Bicciato , Annalisa Chiappella , Paola Ghione , Olivier Elemento , Leandro Cerchietti , Giorgio Inghirami , Francesco Bertoni

Identification of a new family of pyrazolo[3,4-d]pyrimidine derivatives as multitarget Fyn-Blk-Lyn inhibitors active on B- and T-lymphoma cell lines.

European journal of medicinal chemistry

Avec: Anna Lucia Fallacara , Raffaele Passannanti , Mattia Mori , Giulia Iovenitti , Francesca Musumeci , Chiara Greco , Emmanuele Crespan , Miroslava Kissova , Giovanni Maga , Chiara Tarantelli , Filippo Spriano , Eugenio Gaudio , Francesco Bertoni , Maurizio Botta , Silvia Schenone

Single and combined BTK and PI3Kδ inhibition with acalabrutinib and ACP-319 in pre-clinical models of aggressive lymphomas.

British journal of haematology

Avec: Filippo Spriano , Chiara Tarantelli , Eugenio Gaudio , Magdalena M Gerlach , Valdemar Priebe , Luciano Cascione , Elena Bernasconi , Altea Targa , Michele Mascia , Stefan Dirnhofer , Anastasios Stathis , Emanuele Zucca , Francesco Bertoni

Targeting CD205 with the antibody drug conjugate MEN1309/OBT076 is an active new therapeutic strategy in lymphoma models.

Haematologica

Avec: Eugenio Gaudio , Chiara Tarantelli , Filippo Spriano , Francesca Guidetti , Giulio Sartori , Roberta Bordone , Alberto J Arribas , Luciano Cascione , Mario Bigioni , Giuseppe Merlino , Alessio Fiascarelli , Alessandro Bressan , Afua Adjeiwaa Mensah , Gaetanina Golino , Renzo Lucchini , Elena Bernasconi , Davide Rossi , Emanuele Zucca , Georg Stussi , Anastasios Stathis , Robert S Boyd , Rachel L Dusek , Arnima Bisht , Nickolas Attanasio , Christian Rohlff , Andrea Pellacani , Monica Binaschi , Francesco Bertoni

Resistance to PI3Kδ inhibitors in marginal zone lymphoma can be reverted by targeting the IL-6/PDGFRA axis.

Haematologica

Avec: Alberto J Arribas , Sara Napoli , Luciano Cascione , Giulio Sartori , Laura Barnabei , Eugenio Gaudio , Chiara Tarantelli , Afua Adjeiwaa Mensah , Filippo Spriano , Antonella Zucchetto , Francesca M Rossi , Andrea Rinaldi , Manuel Castro de Moura , Sandra Jovic , Roberta Bordone-Pittau , Alessandra Di Veroli , Anastasios Stathis , Gabriele Cruciani , Georg Stussi , Valter Gattei , Jennifer R Brown , Manel Esteller , Emanuele Zucca , Davide Rossi , Francesco Bertoni

Pharmacologic screen identifies active combinations with BET inhibitors and LRRK2 as a novel putative target in lymphoma.

EJHaem

Avec: Filippo Spriano , Giulio Sartori , Chiara Tarantelli , Marilia Barreca , Gaetanina Golino , Andrea Rinaldi , Sara Napoli , Michele Mascia , Lorenzo Scalise , Alberto J Arribas , Luciano Cascione , Emanuele Zucca , Anastasios Stathis , Eugenio Gaudio , Francesco Bertoni

IOA-244 is a Non-ATP-competitive, Highly Selective, Tolerable PI3K Delta Inhibitor That Targets Solid Tumors and Breaks Immune Tolerance.

Cancer research communications

Avec: Zoë Johnson , Chiara Tarantelli , Elisa Civanelli , Luciano Cascione , Filippo Spriano , Amy Fraser , Pritom Shah , Tyzoon Nomanbhoy , Sara Napoli , Andrea Rinaldi , Karolina Niewola-Staszkowska , Michael Lahn , Dominique Perrin , Mathias Wenes , Denis Migliorini , Francesco Bertoni , Lars van der Veen , Giusy Di Conza

Antibody-drug conjugates for lymphoma patients: preclinical and clinical evidences.

Exploration of targeted anti-tumor therapy

Avec: Marilia Barreca , Noémie Lang , Chiara Tarantelli , Filippo Spriano , Paola Barraja , Francesco Bertoni

The ATR inhibitor elimusertib exhibits anti-lymphoma activity and synergizes with the PI3K inhibitor copanlisib.

British journal of haematology

Avec: Giulio Sartori , Chiara Tarantelli , Filippo Spriano , Eugenio Gaudio , Luciano Cascione , Michele Mascia , Marilia Barreca , Alberto J Arribas , Luca Licenziato , Gaetanina Golino , Adele Ferragamo , Stefano Pileri , Giovanna Damia , Emanuele Zucca , Anastasios Stathis , Oliver Politz , Antje M Wengner , Francesco Bertoni

ADCT-602, a novel PBD dimer-containing antibody-drug conjugate for treating CD22-positive hematological malignancies.

Molecular cancer therapeutics

Avec: Francesca Zammarchi , Karin E Havenith , Nikoleta Sachini , Narinder Janghra , Simon Chivers , Esohe Idusogie , Eugenio Gaudio , Chiara Tarantelli , Francois Bertelli , Kathleen Santos , Peter Tyrer , Simon Corbett , Filippo Spriano , Gaetanina Golino , Luciano Cascione , Francesco Bertoni , John A Hartley , Patrick H van Berkel

Targeting CD19-positive lymphomas with the antibody-drug conjugate loncastuximab tesirine: preclinical evidence as single agent and in combination therapy.

Haematologica

Avec: Chiara Tarantelli , David Wald , Nicolas Munz , Filippo Spriano , Alessio Bruscaggin , Eleonora Cannas , Luciano Cascione , Eugenio Gaudio , Alberto J Arribas , Shivaprasad Manjappa , Gaetanina Golino , Lorenzo Scalise , Maria Teresa Cacciapuoti , Emanuele Zucca , Anastasios Stathis , Giorgio Inghirami , Patrick H Van Berkel , Davide Rossi , Paolo F Caimi , Francesca Zammarchi , Francesco Bertoni

Réseau de co-auteurs

Francesco Bertoni 14 collaborations

Chiara Tarantelli 13 collaborations

Luciano Cascione 11 collaborations

Eugenio Gaudio 11 collaborations

Emanuele Zucca 8 collaborations

Anastasios Stathis 8 collaborations

Giulio Sartori 7 collaborations

Andrea Rinaldi 5 collaborations

Alberto J Arribas 5 collaborations

Gaetanina Golino 5 collaborations

Afua Adjeiwaa Mensah 4 collaborations

Sara Napoli 4 collaborations

Giovanna Damia 3 collaborations

Michele Mascia 3 collaborations

Davide Rossi 3 collaborations

Marilia Barreca 3 collaborations

Valdemar Priebe 2 collaborations

Elisa Civanelli 2 collaborations

Luca Aresu 2 collaborations

Francesca Guidetti 2 collaborations

Maria Teresa Cacciapuoti 2 collaborations

Nicolas Munz 2 collaborations

Giorgio Inghirami 2 collaborations

Elena Bernasconi 2 collaborations

Georg Stussi 2 collaborations

Lorenzo Scalise 2 collaborations

Francesca Zammarchi 2 collaborations

Emanuela Lovati 1 collaboration

Claudio Pietra 1 collaboration

Petra Hillmann 1 collaboration

Denise Rageot 1 collaboration

Ivo Kwee 1 collaboration

Florent Beaufils 1 collaboration

Matthias P Wymann 1 collaboration

Vladimir Cmiljanovic 1 collaboration

Doriano Fabbro 1 collaboration

Valentina Restelli 1 collaboration

Monica Lupi 1 collaboration

Rosaria Chilà 1 collaboration

Micaela Vagni 1 collaboration

Laura Carrassa 1 collaboration

Fangwen Zhang 1 collaboration

Mattia Forcato 1 collaboration

Silvio Bicciato 1 collaboration

Annalisa Chiappella 1 collaboration

Paola Ghione 1 collaboration

Olivier Elemento 1 collaboration

Leandro Cerchietti 1 collaboration

Anna Lucia Fallacara 1 collaboration

Raffaele Passannanti 1 collaboration

Mattia Mori 1 collaboration

Giulia Iovenitti 1 collaboration

Francesca Musumeci 1 collaboration

Chiara Greco 1 collaboration

Emmanuele Crespan 1 collaboration

Miroslava Kissova 1 collaboration

Giovanni Maga 1 collaboration

Maurizio Botta 1 collaboration

Silvia Schenone 1 collaboration

Magdalena M Gerlach 1 collaboration

Altea Targa 1 collaboration

Stefan Dirnhofer 1 collaboration

Roberta Bordone 1 collaboration

Mario Bigioni 1 collaboration

Giuseppe Merlino 1 collaboration

Alessio Fiascarelli 1 collaboration

Alessandro Bressan 1 collaboration

Renzo Lucchini 1 collaboration

Robert S Boyd 1 collaboration

Rachel L Dusek 1 collaboration

Arnima Bisht 1 collaboration

Nickolas Attanasio 1 collaboration

Christian Rohlff 1 collaboration

Andrea Pellacani 1 collaboration

Monica Binaschi 1 collaboration

Laura Barnabei 1 collaboration

Antonella Zucchetto 1 collaboration

Francesca M Rossi 1 collaboration

Manuel Castro de Moura 1 collaboration

Sandra Jovic 1 collaboration

Roberta Bordone-Pittau 1 collaboration

Alessandra Di Veroli 1 collaboration

Gabriele Cruciani 1 collaboration

Valter Gattei 1 collaboration

Jennifer R Brown 1 collaboration

Manel Esteller 1 collaboration

Zoë Johnson 1 collaboration

Amy Fraser 1 collaboration

Pritom Shah 1 collaboration

Tyzoon Nomanbhoy 1 collaboration

Karolina Niewola-Staszkowska 1 collaboration

Michael Lahn 1 collaboration

Dominique Perrin 1 collaboration

Mathias Wenes 1 collaboration

Denis Migliorini 1 collaboration

Lars van der Veen 1 collaboration

Giusy Di Conza 1 collaboration

Noémie Lang 1 collaboration

Paola Barraja 1 collaboration

Luca Licenziato 1 collaboration

Adele Ferragamo 1 collaboration

Stefano Pileri 1 collaboration

Oliver Politz 1 collaboration

Antje M Wengner 1 collaboration

Karin E Havenith 1 collaboration

Nikoleta Sachini 1 collaboration

Narinder Janghra 1 collaboration

Simon Chivers 1 collaboration

Esohe Idusogie 1 collaboration

Francois Bertelli 1 collaboration

Kathleen Santos 1 collaboration

Peter Tyrer 1 collaboration

Simon Corbett 1 collaboration

John A Hartley 1 collaboration

Patrick H van Berkel 1 collaboration

David Wald 1 collaboration

Alessio Bruscaggin 1 collaboration

Eleonora Cannas 1 collaboration

Shivaprasad Manjappa 1 collaboration

Patrick H Van Berkel 1 collaboration

Paolo F Caimi 1 collaboration