Francesca Necchi

Affiliations

GSK Vaccines Institute for Global Health S.r.l. (GVGH), Siena, Italy.

ORCID: 0000-0003-2122-9480

Publications (12)

Rationalizing the design of a broad coverage Shigella vaccine based on evaluation of immunological cross-reactivity among S. flexneri serotypes.

PLoS neglected tropical diseases

Avec: Francesco Citiulo , Francesca Necchi , Francesca Mancini , Omar Rossi , Maria Grazia Aruta , Gianmarco Gasperini , Renzo Alfini , Simona Rondini , Francesca Micoli , Rino Rappuoli , Allan Saul , Laura B Martin

GMMA Is a Versatile Platform to Design Effective Multivalent Combination Vaccines.

Vaccines

Avec: Francesca Micoli , Renzo Alfini , Roberta Di Benedetto , Francesca Necchi , Fabiola Schiavo , Francesca Mancini , Martina Carducci , Elena Palmieri , Cristiana Balocchi , Gianmarco Gasperini , Brunella Brunelli , Paolo Costantino , Roberto Adamo , Diego Piccioli , Allan Saul

Generalized Modules for Membrane Antigens as Carrier for Polysaccharides: Impact of Sugar Length, Density, and Attachment Site on the Immune Response Elicited in Animal Models.

Frontiers in immunology

Avec: Francesca Micoli , Renzo Alfini , Roberta Di Benedetto , Francesca Necchi , Fabiola Schiavo , Francesca Mancini , Martina Carducci , Davide Oldrini , Olimpia Pitirollo , Gianmarco Gasperini , Cristiana Balocchi , Nicoletta Bechi , Brunella Brunelli , Diego Piccioli , Roberto Adamo

Investigating the Role of Antigen Orientation on the Immune Response Elicited by

Vaccines

Avec: Renzo Alfini , Brunella Brunelli , Erika Bartolini , Martina Carducci , Enrico Luzzi , Francesca Ferlicca , Scilla Buccato , Barbara Galli , Paola Lo Surdo , Maria Scarselli , Giacomo Romagnoli , Elena Cartocci , Domenico Maione , Silvana Savino , Francesca Necchi , Isabel Delany , Francesca Micoli

Antigen presentation by Follicular Dendritic cells to cognate B cells is pivotal for Generalised Modules for Membrane Antigens (GMMA) immunogenicity.

Vaccine

Avec: Diego Piccioli , Renzo Alfini , Valentina Monaci , Vanessa Arato , Martina Carducci , Maria Grazia Aruta , Omar Rossi , Francesca Necchi , Alessandra Anemona , Erika Bartolini , Francesca Micoli

From an in vivo to an in vitro relative potency (IVRP) assay to fully characterize a multicomponent O-antigen based vaccine against Shigella.

Carbohydrate polymers

Avec: Francesca Necchi , Carlo Giannelli , Alessandra Acquaviva , Renzo Alfini , Valentina Monaci , Vanessa Arato , Omar Rossi , Francesca Micoli

A next-generation GMMA-based vaccine candidate to fight shigellosis.

NPJ vaccines

Avec: Omar Rossi , Francesco Citiulo , Carlo Giannelli , Emilia Cappelletti , Gianmarco Gasperini , Francesca Mancini , Alessandra Acquaviva , Maria Michelina Raso , Luigi Sollai , Renzo Alfini , Maria Grazia Aruta , Claudia Giorgina Vitali , Mariagrazia Pizza , Francesca Necchi , Rino Rappuoli , Laura B Martin , Francesco Berlanda Scorza , Anna Maria Colucci , Francesca Micoli

Intra-Laboratory Evaluation of Luminescence Based High-Throughput Serum Bactericidal Assay (L-SBA) to Determine Bactericidal Activity of Human Sera against

High-throughput

Avec: Omar Rossi , Eleonora Molesti , Allan Saul , Carlo Giannelli , Francesca Micoli , Francesca Necchi

Novel Simple Conjugation Chemistries for Decoration of GMMA with Heterologous Antigens.

International journal of molecular sciences

Avec: Roberta Di Benedetto , Renzo Alfini , Martina Carducci , Maria Grazia Aruta , Luisa Lanzilao , Alessandra Acquaviva , Elena Palmieri , Carlo Giannelli , Francesca Necchi , Allan Saul , Francesca Micoli

Rapid generation of Shigella flexneri GMMA displaying natural or new and cross-reactive O-Antigens.

NPJ vaccines

Avec: Gianmarco Gasperini , Maria Michelina Raso , Fabiola Schiavo , Maria Grazia Aruta , Neil Ravenscroft , Barbara Bellich , Paola Cescutti , Francesca Necchi , Rino Rappuoli , Francesca Micoli

Increasing the High Throughput of a Luminescence-Based Serum Bactericidal Assay (L-SBA).

Biotech (Basel (Switzerland))

Avec: Maria Grazia Aruta , Martina Carducci , Francesca Micoli , Francesca Necchi , Omar Rossi

Age-dependent acquisition of IgG antibodies to

Frontiers in immunology

Avec: Melissa C Kapulu , Esther Muthumbi , Edward Otieno , Omar Rossi , Pietro Ferruzzi , Francesca Necchi , Alessandra Acquaviva , Laura B Martin , Benedict Orindi , Kennedy Mwai , Hillary Kibet , Alfred Mwanzu , Godfrey M Bigogo , Jennifer R Verani , Cecilia Mbae , Christopher Nyundo , Charles N Agoti , Usman Nasir Nakakana , Valentino Conti , Philip Bejon , Samuel Kariuki , J Anthony G Scott , Francesca Micoli , Audino Podda

Réseau de co-auteurs

Francesca Micoli 12 collaborations

Renzo Alfini 8 collaborations

Omar Rossi 7 collaborations

Maria Grazia Aruta 6 collaborations

Martina Carducci 6 collaborations

Gianmarco Gasperini 5 collaborations

Francesca Mancini 4 collaborations

Allan Saul 4 collaborations

Carlo Giannelli 4 collaborations

Alessandra Acquaviva 4 collaborations

Rino Rappuoli 3 collaborations

Laura B Martin 3 collaborations

Roberta Di Benedetto 3 collaborations

Fabiola Schiavo 3 collaborations

Brunella Brunelli 3 collaborations

Diego Piccioli 3 collaborations

Francesco Citiulo 2 collaborations

Elena Palmieri 2 collaborations

Cristiana Balocchi 2 collaborations

Roberto Adamo 2 collaborations

Erika Bartolini 2 collaborations

Valentina Monaci 2 collaborations

Vanessa Arato 2 collaborations

Maria Michelina Raso 2 collaborations

Simona Rondini 1 collaboration

Paolo Costantino 1 collaboration

Davide Oldrini 1 collaboration

Olimpia Pitirollo 1 collaboration

Nicoletta Bechi 1 collaboration

Enrico Luzzi 1 collaboration

Francesca Ferlicca 1 collaboration

Scilla Buccato 1 collaboration

Barbara Galli 1 collaboration

Paola Lo Surdo 1 collaboration

Maria Scarselli 1 collaboration

Giacomo Romagnoli 1 collaboration

Elena Cartocci 1 collaboration

Domenico Maione 1 collaboration

Silvana Savino 1 collaboration

Isabel Delany 1 collaboration

Alessandra Anemona 1 collaboration

Emilia Cappelletti 1 collaboration

Luigi Sollai 1 collaboration

Claudia Giorgina Vitali 1 collaboration

Mariagrazia Pizza 1 collaboration

Francesco Berlanda Scorza 1 collaboration

Anna Maria Colucci 1 collaboration

Eleonora Molesti 1 collaboration

Luisa Lanzilao 1 collaboration

Neil Ravenscroft 1 collaboration

Barbara Bellich 1 collaboration

Paola Cescutti 1 collaboration

Melissa C Kapulu 1 collaboration

Esther Muthumbi 1 collaboration

Edward Otieno 1 collaboration

Pietro Ferruzzi 1 collaboration

Benedict Orindi 1 collaboration

Kennedy Mwai 1 collaboration

Hillary Kibet 1 collaboration

Alfred Mwanzu 1 collaboration

Godfrey M Bigogo 1 collaboration

Jennifer R Verani 1 collaboration

Cecilia Mbae 1 collaboration

Christopher Nyundo 1 collaboration

Charles N Agoti 1 collaboration

Usman Nasir Nakakana 1 collaboration

Valentino Conti 1 collaboration

Philip Bejon 1 collaboration

Samuel Kariuki 1 collaboration

J Anthony G Scott 1 collaboration

Audino Podda 1 collaboration