Frederik Jan Hes

Affiliations

Clinical Sciences, Research Group Genetics, Reproduction and Development, Centre for Medical Genetics, Vrije Universiteit Brussel (VUB), Universitair Ziekenhuis Brussel (UZ Brussel), Laarbeeklaan 101, 1090, Brussels, Belgium.

Publications (15)

Targetable gene fusions identified in radioactive iodine refractory advanced thyroid carcinoma.

European journal of endocrinology

Avec: K van der Tuin , M Ventayol Garcia , W E Corver , M N Khalifa , D Ruano Neto , E P M Corssmit , F J Hes , T P Links , J W A Smit , T S Plantinga , E Kapiteijn , T van Wezel , H Morreau

Germline DLST Variants Promote Epigenetic Modifications in Pheochromocytoma-Paraganglioma.

The Journal of clinical endocrinology and metabolism

Avec: Alexandre Buffet , Juan Zhang , Heggert Rebel , Eleonora P M Corssmit , Jeroen C Jansen , Erik F Hensen , Judith V M G Bovée , Aurélien Morini , Anne-Paule Gimenez-Roqueplo , Frederik J Hes , Peter Devilee , Judith Favier , Jean-Pierre Bayley

Declining detection rates for APC and biallelic MUTYH variants in polyposis patients, implications for DNA testing policy.

European journal of human genetics : EJHG

Avec: Diantha Terlouw , Manon Suerink , Sunny S Singh , Hans J J P Gille , Frederik J Hes , Alexandra M J Langers , Hans Morreau , Hans F A Vasen , Yvonne J Vos , Tom van Wezel , Carli M Tops , Sanne W Ten Broeke , Maartje Nielsen

Mutational Signature Analysis Reveals NTHL1 Deficiency to Cause a Multi-tumor Phenotype.

Cancer cell

Avec: Judith E Grolleman , Richarda M de Voer , Fadwa A Elsayed , Maartje Nielsen , Robbert D A Weren , Claire Palles , Marjolijn J L Ligtenberg , Janet R Vos , Sanne W Ten Broeke , Noel F C C de Miranda , Renske A Kuiper , Eveline J Kamping , Erik A M Jansen , M Elisa Vink-Börger , Isabell Popp , Alois Lang , Isabel Spier , Robert Hüneburg , Paul A James , Na Li , Marija Staninova , Helen Lindsay , David Cockburn , Olivera Spasic-Boskovic , Mark Clendenning , Kevin Sweet , Gabriel Capellá , Wenche Sjursen , Hildegunn Høberg-Vetti , Marjolijn C Jongmans , Kornelia Neveling , Ad Geurts van Kessel , Hans Morreau , Frederik J Hes , Rolf H Sijmons , Hans K Schackert , Clara Ruiz-Ponte , Dagmara Dymerska , Jan Lubinski , Barbara Rivera , William D Foulkes , Ian P Tomlinson , Laura Valle , Daniel D Buchanan , Sue Kenwrick , Julian Adlard , Aleksandar J Dimovski , Ian G Campbell , Stefan Aretz , Detlev Schindler , Tom van Wezel , Nicoline Hoogerbrugge , Roland P Kuiper

Clinical and Molecular Characteristics May Alter Treatment Strategies of Thyroid Malignancies in DICER1 Syndrome.

The Journal of clinical endocrinology and metabolism

Avec: Karin van der Tuin , Leanne de Kock , Eveline J Kamping , Sabine E Hannema , Marie-Jose M Pouwels , Marek Niedziela , Tom van Wezel , Frederik J Hes , Marjolijn C Jongmans , William D Foulkes , Hans Morreau

Genotype-phenotype correlations for pancreatic cancer risk in Dutch melanoma families with pathogenic

Journal of medical genetics

Avec: Kasper A Overbeek , Mar Dm Rodríguez-Girondo , Anja Wagner , Nienke van der Stoep , Peter C van den Akker , Jan C Oosterwijk , Theo A van Os , Lizet E van der Kolk , Hans F A Vasen , Frederik J Hes , Djuna L Cahen , Marco J Bruno , Thomas P Potjer

A heatmap for expected cumulative live birth rate in preimplantation genetic testing for monogenic disorders and chromosomal structural rearrangements.

Journal of assisted reproduction and genetics

Avec: Annelore Van Der Kelen , Kathelijn Keymolen , Wilfried Cools , Anick De Vos , Laura Pölsler , Michel De Vos , Christophe Blockeel , Elia Fernandez-Gallardo , Martine De Rycke , Veerle Berckmoes , Pieter Verdyck , Frederik Jan Hes , Willem Verpoest

Multigene panel sequencing of established and candidate melanoma susceptibility genes in a large cohort of Dutch non-CDKN2A/CDK4 melanoma families.

International journal of cancer

Avec: Thomas P Potjer , Sander Bollen , Anneliese J E M Grimbergen , Remco van Doorn , Nelleke A Gruis , Christi J van Asperen , Frederik J Hes , Nienke van der Stoep , Auteur inconnu

Estimating the penetrance of pathogenic gene variants in families with missing pedigree information.

Statistical methods in medical research

Avec: Marianne A Jonker , Johannes A Rijken , Frederik J Hes , Hein Putter , Erik F Hensen

Are disease-specific patient-reported outcomes measures (PROMs) used in cardiogenetics? A systematic review.

European journal of human genetics : EJHG

Avec: Saar van Pottelberghe , Nina Kupper , Esther Scheirlynck , Ahmad S Amin , Arthur A M Wilde , Nynke Hofman , Edward Callus , Ruth Biller , Julie Nekkebroeck , Sonia Van Dooren , Frederik J Hes , Saskia N van der Crabben

Clinically-relevant Germline Variants in Children with Non-Medullary Thyroid Cancer.

The Journal of clinical endocrinology and metabolism

Avec: Karin van der Tuin , Dina Ruano , Jeroen Knijnenburg , Rob B van der Luijt , Hans Morreau , Thera P Links , Frederik J Hes , Auteur inconnu

Increased Mortality in

Cancers

Avec: Johannes A Rijken , Leonie T van Hulsteijn , Olaf M Dekkers , Nicolasine D Niemeijer , C René Leemans , Karin Eijkelenkamp , Anouk N A van der Horst-Schrivers , Michiel N Kerstens , Anouk van Berkel , Henri J L M Timmers , Henricus P M Kunst , Peter H L T Bisschop , Koen M A Dreijerink , Marieke F van Dooren , Frederik J Hes , Jeroen C Jansen , Eleonora P M Corssmit , Erik F Hensen

Disease expression in juvenile polyposis syndrome: a retrospective survey on a cohort of 221 European patients and comparison with a literature-derived cohort of 473 SMAD4/BMPR1A pathogenic variant carriers.

Genetics in medicine : official journal of the American College of Medical Genetics

Avec: Robert Blatter , Benjamin Tschupp , Stefan Aretz , Inge Bernstein , Chrystelle Colas , D Gareth Evans , Maurizio Genuardi , Frederik J Hes , Robert Hüneburg , Heikki Järvinen , Fiona Lalloo , Gabriela Moeslein , Laura Renkonen-Sinisalo , Nicoletta Resta , Isabel Spier , Dora Varvara , Hans Vasen , Andrew R Latchford , Karl Heinimann

Parameters of poor prognosis in preimplantation genetic testing for monogenic disorders.

Human reproduction (Oxford, England)

Avec: A Van Der Kelen , S Santos-Ribeiro , A De Vos , P Verdyck , M De Rycke , V Berckmoes , H Tournaye , C Blockeel , M De Vos , F J Hes , K Keymolen , W Verpoest

A systematic review and evidence assessment of monogenic gene-disease relationships in human female infertility and differences in sex development.

Human reproduction update

Avec: Annelore Van Der Kelen , Özlem Okutman , Elodie Javey , Münevver Serdarogullari , Charlotte Janssens , Manjusha S Ghosh , Bart J H Dequeker , Florence Perold , Claire Kastner , Emmanuelle Kieffer , Ingrid Segers , Alexander Gheldof , Frederik J Hes , Karen Sermon , Willem Verpoest , Stéphane Viville

Réseau de co-auteurs

Frederik J Hes 12 collaborations

Hans Morreau 4 collaborations

Erik F Hensen 3 collaborations

Tom van Wezel 3 collaborations

F J Hes 2 collaborations

Eleonora P M Corssmit 2 collaborations

Jeroen C Jansen 2 collaborations

Hans F A Vasen 2 collaborations

Sanne W Ten Broeke 2 collaborations

Maartje Nielsen 2 collaborations

Eveline J Kamping 2 collaborations

Isabel Spier 2 collaborations

Robert Hüneburg 2 collaborations

Marjolijn C Jongmans 2 collaborations

William D Foulkes 2 collaborations

Stefan Aretz 2 collaborations

Karin van der Tuin 2 collaborations

Nienke van der Stoep 2 collaborations

Thomas P Potjer 2 collaborations

Annelore Van Der Kelen 2 collaborations

Willem Verpoest 2 collaborations

None None 2 collaborations

Johannes A Rijken 2 collaborations

K van der Tuin 1 collaboration

M Ventayol Garcia 1 collaboration

W E Corver 1 collaboration

M N Khalifa 1 collaboration

D Ruano Neto 1 collaboration

E P M Corssmit 1 collaboration

T P Links 1 collaboration

J W A Smit 1 collaboration

T S Plantinga 1 collaboration

E Kapiteijn 1 collaboration

T van Wezel 1 collaboration

H Morreau 1 collaboration

Alexandre Buffet 1 collaboration

Juan Zhang 1 collaboration

Heggert Rebel 1 collaboration

Judith V M G Bovée 1 collaboration

Aurélien Morini 1 collaboration

Anne-Paule Gimenez-Roqueplo 1 collaboration

Peter Devilee 1 collaboration

Judith Favier 1 collaboration

Jean-Pierre Bayley 1 collaboration

Diantha Terlouw 1 collaboration

Manon Suerink 1 collaboration

Sunny S Singh 1 collaboration

Hans J J P Gille 1 collaboration

Alexandra M J Langers 1 collaboration

Yvonne J Vos 1 collaboration

Carli M Tops 1 collaboration

Judith E Grolleman 1 collaboration

Richarda M de Voer 1 collaboration

Fadwa A Elsayed 1 collaboration

Robbert D A Weren 1 collaboration

Claire Palles 1 collaboration

Marjolijn J L Ligtenberg 1 collaboration

Janet R Vos 1 collaboration

Noel F C C de Miranda 1 collaboration

Renske A Kuiper 1 collaboration

Erik A M Jansen 1 collaboration

M Elisa Vink-Börger 1 collaboration

Isabell Popp 1 collaboration

Alois Lang 1 collaboration

Paul A James 1 collaboration

Na Li 1 collaboration

Marija Staninova 1 collaboration

Helen Lindsay 1 collaboration

David Cockburn 1 collaboration

Olivera Spasic-Boskovic 1 collaboration

Mark Clendenning 1 collaboration

Kevin Sweet 1 collaboration

Gabriel Capellá 1 collaboration

Wenche Sjursen 1 collaboration

Hildegunn Høberg-Vetti 1 collaboration

Kornelia Neveling 1 collaboration

Ad Geurts van Kessel 1 collaboration

Rolf H Sijmons 1 collaboration

Hans K Schackert 1 collaboration

Clara Ruiz-Ponte 1 collaboration

Dagmara Dymerska 1 collaboration

Jan Lubinski 1 collaboration

Barbara Rivera 1 collaboration

Ian P Tomlinson 1 collaboration

Laura Valle 1 collaboration

Daniel D Buchanan 1 collaboration

Sue Kenwrick 1 collaboration

Julian Adlard 1 collaboration

Aleksandar J Dimovski 1 collaboration

Ian G Campbell 1 collaboration

Detlev Schindler 1 collaboration

Nicoline Hoogerbrugge 1 collaboration

Roland P Kuiper 1 collaboration

Leanne de Kock 1 collaboration

Sabine E Hannema 1 collaboration

Marie-Jose M Pouwels 1 collaboration

Marek Niedziela 1 collaboration

Kasper A Overbeek 1 collaboration

Mar Dm Rodríguez-Girondo 1 collaboration

Anja Wagner 1 collaboration

Peter C van den Akker 1 collaboration

Jan C Oosterwijk 1 collaboration

Theo A van Os 1 collaboration

Lizet E van der Kolk 1 collaboration

Djuna L Cahen 1 collaboration

Marco J Bruno 1 collaboration

Kathelijn Keymolen 1 collaboration

Wilfried Cools 1 collaboration

Anick De Vos 1 collaboration

Laura Pölsler 1 collaboration

Michel De Vos 1 collaboration

Christophe Blockeel 1 collaboration

Elia Fernandez-Gallardo 1 collaboration

Martine De Rycke 1 collaboration

Veerle Berckmoes 1 collaboration

Pieter Verdyck 1 collaboration

Sander Bollen 1 collaboration

Anneliese J E M Grimbergen 1 collaboration

Remco van Doorn 1 collaboration

Nelleke A Gruis 1 collaboration

Christi J van Asperen 1 collaboration

Marianne A Jonker 1 collaboration

Hein Putter 1 collaboration

Saar van Pottelberghe 1 collaboration

Nina Kupper 1 collaboration

Esther Scheirlynck 1 collaboration

Ahmad S Amin 1 collaboration

Arthur A M Wilde 1 collaboration

Nynke Hofman 1 collaboration

Edward Callus 1 collaboration

Ruth Biller 1 collaboration

Julie Nekkebroeck 1 collaboration

Sonia Van Dooren 1 collaboration

Saskia N van der Crabben 1 collaboration

Dina Ruano 1 collaboration

Jeroen Knijnenburg 1 collaboration

Rob B van der Luijt 1 collaboration

Thera P Links 1 collaboration

Leonie T van Hulsteijn 1 collaboration

Olaf M Dekkers 1 collaboration

Nicolasine D Niemeijer 1 collaboration

C René Leemans 1 collaboration

Karin Eijkelenkamp 1 collaboration

Anouk N A van der Horst-Schrivers 1 collaboration

Michiel N Kerstens 1 collaboration

Anouk van Berkel 1 collaboration

Henri J L M Timmers 1 collaboration

Henricus P M Kunst 1 collaboration

Peter H L T Bisschop 1 collaboration

Koen M A Dreijerink 1 collaboration

Marieke F van Dooren 1 collaboration

Robert Blatter 1 collaboration

Benjamin Tschupp 1 collaboration

Inge Bernstein 1 collaboration

Chrystelle Colas 1 collaboration

D Gareth Evans 1 collaboration

Maurizio Genuardi 1 collaboration

Heikki Järvinen 1 collaboration

Fiona Lalloo 1 collaboration

Gabriela Moeslein 1 collaboration

Laura Renkonen-Sinisalo 1 collaboration

Nicoletta Resta 1 collaboration

Dora Varvara 1 collaboration

Hans Vasen 1 collaboration

Andrew R Latchford 1 collaboration

Karl Heinimann 1 collaboration

A Van Der Kelen 1 collaboration

S Santos-Ribeiro 1 collaboration

A De Vos 1 collaboration

P Verdyck 1 collaboration

M De Rycke 1 collaboration

V Berckmoes 1 collaboration

H Tournaye 1 collaboration

C Blockeel 1 collaboration

M De Vos 1 collaboration

K Keymolen 1 collaboration

W Verpoest 1 collaboration

Özlem Okutman 1 collaboration

Elodie Javey 1 collaboration

Münevver Serdarogullari 1 collaboration

Charlotte Janssens 1 collaboration

Manjusha S Ghosh 1 collaboration

Bart J H Dequeker 1 collaboration

Florence Perold 1 collaboration

Claire Kastner 1 collaboration

Emmanuelle Kieffer 1 collaboration

Ingrid Segers 1 collaboration

Alexander Gheldof 1 collaboration

Karen Sermon 1 collaboration

Stéphane Viville 1 collaboration