Gerd Multhaup

Affiliations

Department of Pharmacology and Therapeutics, McGill University, Montreal, H3G 1Y6, Canada.

Publications (15)

Mechanisms of amyloid-β34 generation indicate a pivotal role for BACE1 in amyloid homeostasis.

Scientific reports

Avec: Irem Ulku , Filip Liebsch , S Can Akerman , Jana F Schulz , Luka Kulic , Christoph Hock , Claus Pietrzik , Alessandro Di Spiezio , Gopal Thinakaran , Paul Saftig , Gerhard Multhaup

Understanding the Interaction of Polyelectrolyte Architectures with Proteins and Biosystems.

Angewandte Chemie (International ed. in English)

Avec: Katharina Achazi , Rainer Haag , Matthias Ballauff , Jens Dernedde , Jayachandran N Kizhakkedathu , Dusica Maysinger , Gerd Multhaup

The amyloid-β degradation intermediate Aβ34 is pericyte-associated and reduced in brain capillaries of patients with Alzheimer's disease.

Acta neuropathologica communications

Avec: Tunahan Kirabali , Serena Rigotti , Alessandro Siccoli , Filip Liebsch , Adeola Shobo , Christoph Hock , Roger M Nitsch , Gerhard Multhaup , Luka Kulic

Label-free distribution of anti-amyloid D-AIP in Drosophila melanogaster: prevention of Aβ42-induced toxicity without side effects in transgenic flies.

Journal of neurochemistry

Avec: Yifei Zhong , Adeola Shobo , Mark A Hancock , Gerhard Multhaup

Insights into the Impact of Gold Nanoclusters Au

ACS chemical neuroscience

Avec: Dusica Maysinger , Željka Sanader Maršić , Evan Rizzel Gran , Adeola Shobo , Jun-Ray Macairan , Issan Zhang , Martina Perić Bakulić , Rodolphe Antoine , Gerhard Multhaup , Vlasta Bonačić-Kouteckỳ

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer's disease progression.

Nature communications

Avec: Filip Liebsch , Luka Kulic , Charlotte Teunissen , Adeola Shobo , Irem Ulku , Vivienne Engelschalt , Mark A Hancock , Wiesje M van der Flier , Peter Kunach , Pedro Rosa-Neto , Philip Scheltens , Judes Poirier , Paul Saftig , Randall J Bateman , John Breitner , Christoph Hock , Gerhard Multhaup

Plasma Amyloid-Beta Levels in a Pre-Symptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy Pedigree: A Cross-Sectional and Longitudinal Investigation.

International journal of molecular sciences

Avec: Pratishtha Chatterjee , Michelle Tegg , Steve Pedrini , Anne M Fagan , Chengjie Xiong , Abhay K Singh , Kevin Taddei , Samantha Gardener , Colin L Masters , Peter R Schofield , Gerhard Multhaup , Tammie L S Benzinger , John C Morris , Randall J Bateman , Steven M Greenberg , Mark A van Buchem , Erik Stoops , Hugo Vanderstichele , Charlotte E Teunissen , Graeme J Hankey , Marieke J H Wermer , Hamid R Sohrabi , Ralph N Martins , The Dominantly Inherited Alzheimer Network

Inhibition of BACE1 affected both its Aβ producing and degrading activities and increased Aβ42 and Aβ40 levels at high level BACE1 expression.

The Journal of biological chemistry

Avec: Irem Ulku , Rocher Leung , Fritz Herre , Lina Walther , Adeola Shobo , Paul Saftig , Mark A Hancock , Filip Liebsch , Gerd Multhaup

Amyloid Precursor Protein Dimerisation Reduces Neurite Outgrowth.

Molecular neurobiology

Avec: Luan Luu , Giuseppe D Ciccotosto , Laura J Vella , Lesley Cheng , Laila C Roisman , Gerhard Multhaup , Andrew F Hill , Lisa-Marie Munter , Roberto Cappai

Neurodegenerative Disease-Related Proteins within the Epidermal Layer of the Human Skin.

Journal of Alzheimer's disease : JAD

Avec: S Can Akerman , Shireen Hossain , Adeola Shobo , Yifei Zhong , Roland Jourdain , Mark A Hancock , Kelly George , Lionel Breton , Gerhard Multhaup

The amyloid-β

The Journal of biological chemistry

Avec: Adeola Shobo , Nicholas James , Daniel Dai , Alexander Röntgen , Corbin Black , Jean-Robert Kwizera , Mark A Hancock , Khanh Huy Bui , Gerhard Multhaup

Presymptomatic Dutch-Type Hereditary Cerebral Amyloid Angiopathy-Related Blood Metabolite Alterations.

Journal of Alzheimer's disease : JAD

Avec: Pratishtha Chatterjee , Anne M Fagan , Chengjie Xiong , Matthew McKay , Atul Bhatnagar , Yunqi Wu , Abhay K Singh , Kevin Taddei , Ian Martins , Samantha L Gardener , Mark P Molloy , Gerhard Multhaup , Colin L Masters , Peter R Schofield , Tammie L S Benzinger , John C Morris , Randall J Bateman , Steven M Greenberg , Marieke J H Wermer , Mark A van Buchem , Hamid R Sohrabi , Ralph N Martins , Auteur inconnu

Biophysical characterization as a tool to predict amyloidogenic and toxic properties of amyloid-β42 peptides.

FEBS letters

Avec: Adeola Shobo , Alexander Röntgen , Mark A Hancock , Gerhard Multhaup

Cathepsin D: Analysis of its potential role as an amyloid beta degrading protease.

Neurobiology of disease

Avec: Lisa Gallwitz , Lina Schmidt , André R A Marques , Andreas Tholey , Liam Cassidy , Irem Ulku , Gerhard Multhaup , Alessandro Di Spiezio , Paul Saftig

Sulfated Hyperbranched and Linear Polyglycerols Modulate HMGB1 and Morphological Plasticity in Neural Cells.

ACS chemical neuroscience

Avec: Dusica Maysinger , Issan Zhang , Pei You Wu , Marten Kagelmacher , Haiming Daniel Luo , Jayachandran N Kizhakkedathu , Jens Dernedde , Matthias Ballauff , Rainer Haag , Adeola Shobo , Gerhard Multhaup , R Anne McKinney

Réseau de co-auteurs

Gerhard Multhaup 13 collaborations

Adeola Shobo 9 collaborations

Mark A Hancock 6 collaborations

Irem Ulku 4 collaborations

Filip Liebsch 4 collaborations

Paul Saftig 4 collaborations

Luka Kulic 3 collaborations

Christoph Hock 3 collaborations

Dusica Maysinger 3 collaborations

Randall J Bateman 3 collaborations

S Can Akerman 2 collaborations

Alessandro Di Spiezio 2 collaborations

Rainer Haag 2 collaborations

Matthias Ballauff 2 collaborations

Jens Dernedde 2 collaborations

Jayachandran N Kizhakkedathu 2 collaborations

Yifei Zhong 2 collaborations

Issan Zhang 2 collaborations

Pratishtha Chatterjee 2 collaborations

Anne M Fagan 2 collaborations

Chengjie Xiong 2 collaborations

Abhay K Singh 2 collaborations

Kevin Taddei 2 collaborations

Colin L Masters 2 collaborations

Peter R Schofield 2 collaborations

Tammie L S Benzinger 2 collaborations

John C Morris 2 collaborations

Steven M Greenberg 2 collaborations

Mark A van Buchem 2 collaborations

Marieke J H Wermer 2 collaborations

Hamid R Sohrabi 2 collaborations

Ralph N Martins 2 collaborations

Alexander Röntgen 2 collaborations

Jana F Schulz 1 collaboration

Claus Pietrzik 1 collaboration

Gopal Thinakaran 1 collaboration

Katharina Achazi 1 collaboration

Tunahan Kirabali 1 collaboration

Serena Rigotti 1 collaboration

Alessandro Siccoli 1 collaboration

Roger M Nitsch 1 collaboration

Željka Sanader Maršić 1 collaboration

Evan Rizzel Gran 1 collaboration

Jun-Ray Macairan 1 collaboration

Martina Perić Bakulić 1 collaboration

Rodolphe Antoine 1 collaboration

Vlasta Bonačić-Kouteckỳ 1 collaboration

Charlotte Teunissen 1 collaboration

Vivienne Engelschalt 1 collaboration

Wiesje M van der Flier 1 collaboration

Peter Kunach 1 collaboration

Pedro Rosa-Neto 1 collaboration

Philip Scheltens 1 collaboration

Judes Poirier 1 collaboration

John Breitner 1 collaboration

Michelle Tegg 1 collaboration

Steve Pedrini 1 collaboration

Samantha Gardener 1 collaboration

Erik Stoops 1 collaboration

Hugo Vanderstichele 1 collaboration

Charlotte E Teunissen 1 collaboration

Graeme J Hankey 1 collaboration

None The Dominantly Inherited Alzheimer Network 1 collaboration

Rocher Leung 1 collaboration

Fritz Herre 1 collaboration

Lina Walther 1 collaboration

Luan Luu 1 collaboration

Giuseppe D Ciccotosto 1 collaboration

Laura J Vella 1 collaboration

Lesley Cheng 1 collaboration

Laila C Roisman 1 collaboration

Andrew F Hill 1 collaboration

Lisa-Marie Munter 1 collaboration

Roberto Cappai 1 collaboration

Shireen Hossain 1 collaboration

Roland Jourdain 1 collaboration

Kelly George 1 collaboration

Lionel Breton 1 collaboration

Nicholas James 1 collaboration

Daniel Dai 1 collaboration

Corbin Black 1 collaboration

Jean-Robert Kwizera 1 collaboration

Khanh Huy Bui 1 collaboration

Matthew McKay 1 collaboration

Atul Bhatnagar 1 collaboration

Yunqi Wu 1 collaboration

Ian Martins 1 collaboration

Samantha L Gardener 1 collaboration

Mark P Molloy 1 collaboration

None None 1 collaboration

Lisa Gallwitz 1 collaboration

Lina Schmidt 1 collaboration

André R A Marques 1 collaboration

Andreas Tholey 1 collaboration

Liam Cassidy 1 collaboration

Pei You Wu 1 collaboration

Marten Kagelmacher 1 collaboration

Haiming Daniel Luo 1 collaboration

R Anne McKinney 1 collaboration