Gordon J Freeman

Affiliations

Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts.

Publications (8)

irRECIST for the Evaluation of Candidate Biomarkers of Response to Nivolumab in Metastatic Clear Cell Renal Cell Carcinoma: Analysis of a Phase II Prospective Clinical Trial.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jean-Christophe Pignon , Opeyemi Jegede , Sachet A Shukla , David A Braun , Christine E Horak , Megan Wind-Rotolo , Yuko Ishii , Paul J Catalano , Jonian Grosha , Abdallah Flaifel , Jesse S Novak , Kathleen M Mahoney , Gordon J Freeman , Arlene H Sharpe , F Stephen Hodi , Robert J Motzer , Toni K Choueiri , Catherine J Wu , Michael B Atkins , David F McDermott , Sabina Signoretti

Immuno-PET identifies the myeloid compartment as a key contributor to the outcome of the antitumor response under PD-1 blockade.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Mohammad Rashidian , Martin W LaFleur , Vincent L Verschoor , Anushka Dongre , Yun Zhang , Thao H Nguyen , Stephen Kolifrath , Amir R Aref , Christie J Lau , Cloud P Paweletz , Xia Bu , Gordon J Freeman , M Inmaculada Barrasa , Robert A Weinberg , Arlene H Sharpe , Hidde L Ploegh

PD-L1 Expression and Clinical Outcomes to Cabozantinib, Everolimus, and Sunitinib in Patients with Metastatic Renal Cell Carcinoma: Analysis of the Randomized Clinical Trials METEOR and CABOSUN.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Abdallah Flaifel , Wanling Xie , David A Braun , Miriam Ficial , Ziad Bakouny , Amin H Nassar , Rebecca B Jennings , Bernard Escudier , Daniel J George , Robert J Motzer , Michael J Morris , Thomas Powles , Evelyn Wang , Ying Huang , Gordon J Freeman , Toni K Choueiri , Sabina Signoretti

Results of a Multicenter Phase II Study of Atezolizumab and Bevacizumab for Patients With Metastatic Renal Cell Carcinoma With Variant Histology and/or Sarcomatoid Features.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Bradley A McGregor , Rana R McKay , David A Braun , Lillian Werner , Kathryn Gray , Abdallah Flaifel , Sabina Signoretti , Michelle S Hirsch , John A Steinharter , Ziad Bakouny , Ronan Flippot , Xiao X Wei , Atish Choudhury , Kerry Kilbridge , Gordon J Freeman , Eliezer M Van Allen , Lauren C Harshman , David F McDermott , Ulka Vaishampayan , Toni K Choueiri

Intratumoral Activity of the CXCR3 Chemokine System Is Required for the Efficacy of Anti-PD-1 Therapy.

Immunity

Avec: Melvyn T Chow , Aleksandra J Ozga , Rachel L Servis , Dennie T Frederick , Jennifer A Lo , David E Fisher , Gordon J Freeman , Genevieve M Boland , Andrew D Luster

Metabolomic adaptations and correlates of survival to immune checkpoint blockade.

Nature communications

Avec: Haoxin Li , Kevin Bullock , Carino Gurjao , David Braun , Sachet A Shukla , Dominick Bossé , Aly-Khan A Lalani , Shuba Gopal , Chelsea Jin , Christine Horak , Megan Wind-Rotolo , Sabina Signoretti , David F McDermott , Gordon J Freeman , Eliezer M Van Allen , Stuart L Schreiber , F Stephen Hodi , William R Sellers , Levi A Garraway , Clary B Clish , Toni K Choueiri , Marios Giannakis

High-fidelity detection and sorting of nanoscale vesicles in viral disease and cancer.

Journal of extracellular vesicles

Avec: Aizea Morales-Kastresana , Thomas A Musich , Joshua A Welsh , William Telford , Thorsten Demberg , James C S Wood , Marty Bigos , Carley D Ross , Aliaksander Kachynski , Alan Dean , Edward J Felton , Jonathan Van Dyke , John Tigges , Vasilis Toxavidis , David R Parks , W Roy Overton , Aparna H Kesarwala , Gordon J Freeman , Ariel Rosner , Stephen P Perfetto , Lise Pasquet , Masaki Terabe , Katherine McKinnon , Veena Kapoor , Jane B Trepel , Anu Puri , Hisataka Kobayashi , Bryant Yung , Xiaoyuan Chen , Peter Guion , Peter Choyke , Susan J Knox , Ionita Ghiran , Marjorie Robert-Guroff , Jay A Berzofsky , Jennifer C Jones

Author Correction: Cyclin D-CDK4 kinase destabilizes PD-L1 via cullin 3-SPOP to control cancer immune surveillance.

Nature

Avec: Jinfang Zhang , Xia Bu , Haizhen Wang , Yasheng Zhu , Yan Geng , Naoe Taira Nihira , Yuyong Tan , Yanpeng Ci , Fei Wu , Xiangpeng Dai , Jianping Guo , Yu-Han Huang , Caoqi Fan , Shancheng Ren , Yinghao Sun , Gordon J Freeman , Piotr Sicinski , Wenyi Wei

Réseau de co-auteurs

Toni K Choueiri 4 collaborations

Sabina Signoretti 4 collaborations

David A Braun 3 collaborations

Abdallah Flaifel 3 collaborations

David F McDermott 3 collaborations

Sachet A Shukla 2 collaborations

Megan Wind-Rotolo 2 collaborations

Arlene H Sharpe 2 collaborations

F Stephen Hodi 2 collaborations

Robert J Motzer 2 collaborations

Xia Bu 2 collaborations

Ziad Bakouny 2 collaborations

Eliezer M Van Allen 2 collaborations

Jean-Christophe Pignon 1 collaboration

Opeyemi Jegede 1 collaboration

Christine E Horak 1 collaboration

Yuko Ishii 1 collaboration

Paul J Catalano 1 collaboration

Jonian Grosha 1 collaboration

Jesse S Novak 1 collaboration

Kathleen M Mahoney 1 collaboration

Catherine J Wu 1 collaboration

Michael B Atkins 1 collaboration

Mohammad Rashidian 1 collaboration

Martin W LaFleur 1 collaboration

Vincent L Verschoor 1 collaboration

Anushka Dongre 1 collaboration

Yun Zhang 1 collaboration

Thao H Nguyen 1 collaboration

Stephen Kolifrath 1 collaboration

Amir R Aref 1 collaboration

Christie J Lau 1 collaboration

Cloud P Paweletz 1 collaboration

M Inmaculada Barrasa 1 collaboration

Robert A Weinberg 1 collaboration

Hidde L Ploegh 1 collaboration

Wanling Xie 1 collaboration

Miriam Ficial 1 collaboration

Amin H Nassar 1 collaboration

Rebecca B Jennings 1 collaboration

Bernard Escudier 1 collaboration

Daniel J George 1 collaboration

Michael J Morris 1 collaboration

Thomas Powles 1 collaboration

Evelyn Wang 1 collaboration

Ying Huang 1 collaboration

Bradley A McGregor 1 collaboration

Rana R McKay 1 collaboration

Lillian Werner 1 collaboration

Kathryn Gray 1 collaboration

Michelle S Hirsch 1 collaboration

John A Steinharter 1 collaboration

Ronan Flippot 1 collaboration

Xiao X Wei 1 collaboration

Atish Choudhury 1 collaboration

Kerry Kilbridge 1 collaboration

Lauren C Harshman 1 collaboration

Ulka Vaishampayan 1 collaboration

Melvyn T Chow 1 collaboration

Aleksandra J Ozga 1 collaboration

Rachel L Servis 1 collaboration

Dennie T Frederick 1 collaboration

Jennifer A Lo 1 collaboration

David E Fisher 1 collaboration

Genevieve M Boland 1 collaboration

Andrew D Luster 1 collaboration

Haoxin Li 1 collaboration

Kevin Bullock 1 collaboration

Carino Gurjao 1 collaboration

David Braun 1 collaboration

Dominick Bossé 1 collaboration

Aly-Khan A Lalani 1 collaboration

Shuba Gopal 1 collaboration

Chelsea Jin 1 collaboration

Christine Horak 1 collaboration

Stuart L Schreiber 1 collaboration

William R Sellers 1 collaboration

Levi A Garraway 1 collaboration

Clary B Clish 1 collaboration

Marios Giannakis 1 collaboration

Aizea Morales-Kastresana 1 collaboration

Thomas A Musich 1 collaboration

Joshua A Welsh 1 collaboration

William Telford 1 collaboration

Thorsten Demberg 1 collaboration

James C S Wood 1 collaboration

Marty Bigos 1 collaboration

Carley D Ross 1 collaboration

Aliaksander Kachynski 1 collaboration

Alan Dean 1 collaboration

Edward J Felton 1 collaboration

Jonathan Van Dyke 1 collaboration

John Tigges 1 collaboration

Vasilis Toxavidis 1 collaboration

David R Parks 1 collaboration

W Roy Overton 1 collaboration

Aparna H Kesarwala 1 collaboration

Ariel Rosner 1 collaboration

Stephen P Perfetto 1 collaboration

Lise Pasquet 1 collaboration

Masaki Terabe 1 collaboration

Katherine McKinnon 1 collaboration

Veena Kapoor 1 collaboration

Jane B Trepel 1 collaboration

Anu Puri 1 collaboration

Hisataka Kobayashi 1 collaboration

Bryant Yung 1 collaboration

Xiaoyuan Chen 1 collaboration

Peter Guion 1 collaboration

Peter Choyke 1 collaboration

Susan J Knox 1 collaboration

Ionita Ghiran 1 collaboration

Marjorie Robert-Guroff 1 collaboration

Jay A Berzofsky 1 collaboration

Jennifer C Jones 1 collaboration

Jinfang Zhang 1 collaboration

Haizhen Wang 1 collaboration

Yasheng Zhu 1 collaboration

Yan Geng 1 collaboration

Naoe Taira Nihira 1 collaboration

Yuyong Tan 1 collaboration

Yanpeng Ci 1 collaboration

Fei Wu 1 collaboration

Xiangpeng Dai 1 collaboration

Jianping Guo 1 collaboration

Yu-Han Huang 1 collaboration

Caoqi Fan 1 collaboration

Shancheng Ren 1 collaboration

Yinghao Sun 1 collaboration

Piotr Sicinski 1 collaboration

Wenyi Wei 1 collaboration