Guy M Lenk

Affiliations

Department of Human Genetics, University of Michigan, Ann Arbor, MI.

ORCID: 0000-0001-8092-1405

Publications (5)

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

Annals of neurology

Avec: Guy M Lenk , Paymaan Jafar-Nejad , Sophie F Hill , Lucas D Huffman , Corrine E Smolen , Jacy L Wagnon , Hayley Petit , Wenxi Yu , Julie Ziobro , Kritika Bhatia , Jack Parent , Roman J Giger , Frank Rigo , Miriam H Meisler

Chloroquine corrects enlarged lysosomes in FIG4 null cells and reduces neurodegeneration in Fig4 null mice.

Molecular genetics and metabolism

Avec: Guy M Lenk , Miriam H Meisler

A model organism pipeline provides insight into the clinical heterogeneity of TARS1 loss-of-function variants.

HGG advances

Avec: Rebecca Meyer-Schuman , Allison R Cale , Jennifer A Pierluissi , Kira E Jonatzke , Young N Park , Guy M Lenk , Stephanie N Oprescu , Marina A Grachtchouk , Andrzej A Dlugosz , Asim A Beg , Miriam H Meisler , Anthony Antonellis

Cerebral hypomyelination associated with biallelic variants of FIG4.

Human mutation

Avec: Guy M Lenk , Ian R Berry , Chloe A Stutterd , Moira Blyth , Lydia Green , Gayatri Vadlamani , Daniel Warren , Ian Craven , Miriam Fanjul-Fernandez , Victoria Rodriguez-Casero , Paul J Lockhart , Adeline Vanderver , Cas Simons , Susan Gibb , Simon Sadedin , Auteur inconnu , Susan M White , John Christodoulou , Olga Skibina , Jonathan Ruddle , Tiong Y Tan , Richard J Leventer , John H Livingston , Miriam H Meisler

The chloride antiporter CLCN7 is a modifier of lysosome dysfunction in FIG4 and VAC14 mutants.

PLoS genetics

Avec: Xu Cao , Guy M Lenk , Vedrana Mikusevic , Joseph A Mindell , Miriam H Meisler

Réseau de co-auteurs

Miriam H Meisler 5 collaborations

Paymaan Jafar-Nejad 1 collaboration

Sophie F Hill 1 collaboration

Lucas D Huffman 1 collaboration

Corrine E Smolen 1 collaboration

Jacy L Wagnon 1 collaboration

Hayley Petit 1 collaboration

Wenxi Yu 1 collaboration

Julie Ziobro 1 collaboration

Kritika Bhatia 1 collaboration

Jack Parent 1 collaboration

Roman J Giger 1 collaboration

Frank Rigo 1 collaboration

Rebecca Meyer-Schuman 1 collaboration

Allison R Cale 1 collaboration

Jennifer A Pierluissi 1 collaboration

Kira E Jonatzke 1 collaboration

Young N Park 1 collaboration

Stephanie N Oprescu 1 collaboration

Marina A Grachtchouk 1 collaboration

Andrzej A Dlugosz 1 collaboration

Asim A Beg 1 collaboration

Anthony Antonellis 1 collaboration

Ian R Berry 1 collaboration

Chloe A Stutterd 1 collaboration

Moira Blyth 1 collaboration

Lydia Green 1 collaboration

Gayatri Vadlamani 1 collaboration

Daniel Warren 1 collaboration

Ian Craven 1 collaboration

Miriam Fanjul-Fernandez 1 collaboration

Victoria Rodriguez-Casero 1 collaboration

Paul J Lockhart 1 collaboration

Adeline Vanderver 1 collaboration

Cas Simons 1 collaboration

Susan Gibb 1 collaboration

Simon Sadedin 1 collaboration

None None 1 collaboration

Susan M White 1 collaboration

John Christodoulou 1 collaboration

Olga Skibina 1 collaboration

Jonathan Ruddle 1 collaboration

Tiong Y Tan 1 collaboration

Richard J Leventer 1 collaboration

John H Livingston 1 collaboration

Xu Cao 1 collaboration

Vedrana Mikusevic 1 collaboration

Joseph A Mindell 1 collaboration