Helen Killick

Affiliations

Translational Science and Experimental Medicine, Research and Early Development, Respiratory and Immunology, BioPharmaceuticals R&D, AstraZeneca, Cambridge, UK.

Publications (6)

A randomized phase 1 study of the anti-interleukin-33 antibody tozorakimab in healthy adults and patients with chronic obstructive pulmonary disease.

Clinical pharmacology and therapeutics

Avec: Fred Reid , Dave Singh , Muna Albayaty , Rachel Moate , Eulalia Jimenez , Muhammad Waqas Sadiq , David Howe , Monica Gavala , Helen Killick , Adam Williams , Surekha Krishnan , Alex Godwood , Animesh Shukla , Lisa Hewitt , Alejhandra Lei , Chris Kell , Hitesh Pandya , Paul Newcombe , Nicholas White , Ian C Scott , E Suzanne Cohen

Neutrophil GM-CSF receptor dynamics in acute lung injury.

Journal of leukocyte biology

Avec: Silvia De Alessandris , G John Ferguson , Alison J Dodd , Jatinder K Juss , Abhinandan Devaprasad , Siân Piper , Owen Wyatt , Helen Killick , Dominic J Corkill , E Suzanne Cohen , Aridaman Pandit , Timothy R D J Radstake , Rosalind Simmonds , Alison M Condliffe , Matthew A Sleeman , Andrew S Cowburn , Donna K Finch , Edwin R Chilvers

Altered Differentiation and Inflammation Profiles Contribute to Enhanced Innate Responses in Severe COPD Epithelium to Rhinovirus Infection.

Frontiers in medicine

Avec: Hong Guo-Parke , Dermot Linden , Aurelie Mousnier , Ian C Scott , Helen Killick , Lee A Borthwick , Andrew J Fisher , Sinéad Weldon , Clifford C Taggart , Joseph C Kidney

Oxidised IL-33 drives COPD epithelial pathogenesis

The European respiratory journal

Avec: Sam Strickson , Kirsty F Houslay , Victor A Negri , Yoichiro Ohne , Tomas Ottosson , Roger B Dodd , Catherine Chaillan Huntington , Tina Baker , Jingjing Li , Katherine E Stephenson , Andy J O'Connor , J Sophie Sagawe , Helen Killick , Tom Moore , D Gareth Rees , Sofia Koch , Caroline Sanden , Yixin Wang , Elise Gubbins , Mahboobe Ghaedi , Roland Kolbeck , Saumyaa Saumyaa , Jonas S Erjefält , Gary P Sims , Alison A Humbles , Ian C Scott , Xavier Romero Ros , E Suzanne Cohen

Population pharmacokinetic/target engagement modelling of tozorakimab in healthy volunteers and patients with chronic obstructive pulmonary disease.

British journal of clinical pharmacology

Avec: Muhammad Waqas Sadiq , Hongtao Yu , Magnus Åstrand , Ian C Scott , Adam Williams , Lisa Hewitt , Nicholas White , Helen Killick , Monica Gavala , E Suzanne Cohen , Fred Reid , Chris Kell , Hitesh Pandya , Eulalia Jimenez

Nasal IL-13 production identifies patients with late-phase allergic responses.

The Journal of allergy and clinical immunology

Avec: Nicholas J Campion , Sergio Villazala-Merino , Ryan S Thwaites , Victoria Stanek , Helen Killick , Eleftheria Pertsinidou , Mohammed Zghaebi , Josef Toth , Renate Fröschl , Thomas Perkmann , Katharina Gangl , Sven Schneider , Robin Ristl , Ian C Scott , Emma Suzanne Cohen , Magnus Molin , Margit Focke-Tejkl , Guenther Regelsberger , Trevor T Hansel , Rudolf Valenta , Verena Niederberger-Leppin , Julia Eckl-Dorna

Réseau de co-auteurs

Ian C Scott 5 collaborations

E Suzanne Cohen 4 collaborations

Fred Reid 2 collaborations

Eulalia Jimenez 2 collaborations

Muhammad Waqas Sadiq 2 collaborations

Monica Gavala 2 collaborations

Adam Williams 2 collaborations

Lisa Hewitt 2 collaborations

Chris Kell 2 collaborations

Hitesh Pandya 2 collaborations

Nicholas White 2 collaborations

Dave Singh 1 collaboration

Muna Albayaty 1 collaboration

Rachel Moate 1 collaboration

David Howe 1 collaboration

Surekha Krishnan 1 collaboration

Alex Godwood 1 collaboration

Animesh Shukla 1 collaboration

Alejhandra Lei 1 collaboration

Paul Newcombe 1 collaboration

Silvia De Alessandris 1 collaboration

G John Ferguson 1 collaboration

Alison J Dodd 1 collaboration

Jatinder K Juss 1 collaboration

Abhinandan Devaprasad 1 collaboration

Siân Piper 1 collaboration

Owen Wyatt 1 collaboration

Dominic J Corkill 1 collaboration

Aridaman Pandit 1 collaboration

Timothy R D J Radstake 1 collaboration

Rosalind Simmonds 1 collaboration

Alison M Condliffe 1 collaboration

Matthew A Sleeman 1 collaboration

Andrew S Cowburn 1 collaboration

Donna K Finch 1 collaboration

Edwin R Chilvers 1 collaboration

Hong Guo-Parke 1 collaboration

Dermot Linden 1 collaboration

Aurelie Mousnier 1 collaboration

Lee A Borthwick 1 collaboration

Andrew J Fisher 1 collaboration

Sinéad Weldon 1 collaboration

Clifford C Taggart 1 collaboration

Joseph C Kidney 1 collaboration

Sam Strickson 1 collaboration

Kirsty F Houslay 1 collaboration

Victor A Negri 1 collaboration

Yoichiro Ohne 1 collaboration

Tomas Ottosson 1 collaboration

Roger B Dodd 1 collaboration

Catherine Chaillan Huntington 1 collaboration

Tina Baker 1 collaboration

Jingjing Li 1 collaboration

Katherine E Stephenson 1 collaboration

Andy J O'Connor 1 collaboration

J Sophie Sagawe 1 collaboration

Tom Moore 1 collaboration

D Gareth Rees 1 collaboration

Sofia Koch 1 collaboration

Caroline Sanden 1 collaboration

Yixin Wang 1 collaboration

Elise Gubbins 1 collaboration

Mahboobe Ghaedi 1 collaboration

Roland Kolbeck 1 collaboration

Saumyaa Saumyaa 1 collaboration

Jonas S Erjefält 1 collaboration

Gary P Sims 1 collaboration

Alison A Humbles 1 collaboration

Xavier Romero Ros 1 collaboration

Hongtao Yu 1 collaboration

Magnus Åstrand 1 collaboration

Nicholas J Campion 1 collaboration

Sergio Villazala-Merino 1 collaboration

Ryan S Thwaites 1 collaboration

Victoria Stanek 1 collaboration

Eleftheria Pertsinidou 1 collaboration

Mohammed Zghaebi 1 collaboration

Josef Toth 1 collaboration

Renate Fröschl 1 collaboration

Thomas Perkmann 1 collaboration

Katharina Gangl 1 collaboration

Sven Schneider 1 collaboration

Robin Ristl 1 collaboration

Emma Suzanne Cohen 1 collaboration

Magnus Molin 1 collaboration

Margit Focke-Tejkl 1 collaboration

Guenther Regelsberger 1 collaboration

Trevor T Hansel 1 collaboration

Rudolf Valenta 1 collaboration

Verena Niederberger-Leppin 1 collaboration

Julia Eckl-Dorna 1 collaboration