Iain Kilty

Affiliations

Quench Bio, Inc., Cambridge, MA, USA.

Publications (6)

Quantifying Cell Death Induced by the NLRC4 Inflammasome.

Methods in molecular biology (Clifton, N.J.)

Avec: Stefan Emming , Mercedes M Monteleone , Hiroto Kambara , Alina Starchenko , Jennifer Alley , Michael A Nolan , Wei Li , Iain Kilty , Kate Schroder

Defective bacterial phagocytosis is associated with dysfunctional mitochondria in COPD macrophages.

The European respiratory journal

Avec: Kylie B R Belchamber , Richa Singh , Craig M Batista , Moira K Whyte , David H Dockrell , Iain Kilty , Matthew J Robinson , Jadwiga A Wedzicha , Peter J Barnes , Louise E Donnelly , Auteur inconnu

PF-06651600, a Dual JAK3/TEC Family Kinase Inhibitor.

ACS chemical biology

Avec: Hua Xu , Michael I Jesson , Uthpala I Seneviratne , Tsung H Lin , M Nusrat Sharif , Liang Xue , Chuong Nguyen , Robert A Everley , John I Trujillo , Douglas S Johnson , Gary R Point , Atli Thorarensen , Iain Kilty , Jean-Baptiste Telliez

The role of phosphodiesterase 4 in the pathophysiology of atopic dermatitis and the perspective for its inhibition.

Experimental dermatology

Avec: Emma Guttman-Yassky , Jon M Hanifin , Mark Boguniewicz , Andreas Wollenberg , Robert Bissonnette , Vivek Purohit , Iain Kilty , Anna M Tallman , Michael A Zielinski

The Interleukin-1 Receptor-Associated Kinase 4 Inhibitor PF-06650833 Blocks Inflammation in Preclinical Models of Rheumatic Disease and in Humans Enrolled in a Randomized Clinical Trial.

Arthritis & rheumatology (Hoboken, N.J.)

Avec: Aaron Winkler , Weiyong Sun , Saurav De , Aiping Jiao , M Nusrat Sharif , Peter T Symanowicz , Shruti Athale , Julia H Shin , Ju Wang , Bruce A Jacobson , Simeon J Ramsey , Ken Dower , Tatyana Andreyeva , Heng Liu , Martin Hegen , Bruce L Homer , Joanne Brodfuehrer , Mera Tilley , Steven A Gilbert , Spencer I Danto , Jean J Beebe , Betsy J Barnes , Virginia Pascual , Lih-Ling Lin , Iain Kilty , Margaret Fleming , Vikram R Rao

Safety, tolerability, pharmacokinetics, and pharmacodynamics of PF-06650833, a selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor, in single and multiple ascending dose randomized phase 1 studies in healthy subjects.

Arthritis research & therapy

Avec: Spencer I Danto , Negin Shojaee , Ravi Shankar P Singh , Cheryl Li , Steven A Gilbert , Zorayr Manukyan , Iain Kilty

Réseau de co-auteurs

M Nusrat Sharif 2 collaborations

Steven A Gilbert 2 collaborations

Spencer I Danto 2 collaborations

Stefan Emming 1 collaboration

Mercedes M Monteleone 1 collaboration

Hiroto Kambara 1 collaboration

Alina Starchenko 1 collaboration

Jennifer Alley 1 collaboration

Michael A Nolan 1 collaboration

Wei Li 1 collaboration

Kate Schroder 1 collaboration

Kylie B R Belchamber 1 collaboration

Richa Singh 1 collaboration

Craig M Batista 1 collaboration

Moira K Whyte 1 collaboration

David H Dockrell 1 collaboration

Matthew J Robinson 1 collaboration

Jadwiga A Wedzicha 1 collaboration

Peter J Barnes 1 collaboration

Louise E Donnelly 1 collaboration

None None 1 collaboration

Hua Xu 1 collaboration

Michael I Jesson 1 collaboration

Uthpala I Seneviratne 1 collaboration

Tsung H Lin 1 collaboration

Liang Xue 1 collaboration

Chuong Nguyen 1 collaboration

Robert A Everley 1 collaboration

John I Trujillo 1 collaboration

Douglas S Johnson 1 collaboration

Gary R Point 1 collaboration

Atli Thorarensen 1 collaboration

Jean-Baptiste Telliez 1 collaboration

Emma Guttman-Yassky 1 collaboration

Jon M Hanifin 1 collaboration

Mark Boguniewicz 1 collaboration

Andreas Wollenberg 1 collaboration

Robert Bissonnette 1 collaboration

Vivek Purohit 1 collaboration

Anna M Tallman 1 collaboration

Michael A Zielinski 1 collaboration

Aaron Winkler 1 collaboration

Weiyong Sun 1 collaboration

Saurav De 1 collaboration

Aiping Jiao 1 collaboration

Peter T Symanowicz 1 collaboration

Shruti Athale 1 collaboration

Julia H Shin 1 collaboration

Ju Wang 1 collaboration

Bruce A Jacobson 1 collaboration

Simeon J Ramsey 1 collaboration

Ken Dower 1 collaboration

Tatyana Andreyeva 1 collaboration

Heng Liu 1 collaboration

Martin Hegen 1 collaboration

Bruce L Homer 1 collaboration

Joanne Brodfuehrer 1 collaboration

Mera Tilley 1 collaboration

Jean J Beebe 1 collaboration

Betsy J Barnes 1 collaboration

Virginia Pascual 1 collaboration

Lih-Ling Lin 1 collaboration

Margaret Fleming 1 collaboration

Vikram R Rao 1 collaboration

Negin Shojaee 1 collaboration

Ravi Shankar P Singh 1 collaboration

Cheryl Li 1 collaboration

Zorayr Manukyan 1 collaboration