Ian Gurrell

Affiliations

Neuroscience IMED Biotech Unit, AstraZeneca, AKB, Cambridge, UK.

Publications (4)

A peptide derived from melanotransferrin delivers a protein-based interleukin 1 receptor antagonist across the BBB and ameliorates neuropathic pain in a preclinical model.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism

Avec: George Thom , Mei-Mei Tian , Jon P Hatcher , Natalia Rodrigo , Matthew Burrell , Ian Gurrell , Timothy Z Vitalis , Thomas Abraham , Wilfred A Jefferies , Carl I Webster , Reinhard Gabathuler

Preclinical development of a high affinity α-synuclein antibody, MEDI1341, that can enter the brain, sequester extracellular α-synuclein and attenuate α-synuclein spreading in vivo.

Neurobiology of disease

Avec: Darren J Schofield , Lorraine Irving , Laura Calo , Anna Bogstedt , Gareth Rees , Annalisa Nuccitelli , Rajesh Narwal , Marcella Petrone , Jennifer Roberts , Lee Brown , Fiona Cusdin , Bhupinder Dosanjh , Christopher Lloyd , Claire Dobson , Ian Gurrell , Graham Fraser , Mary McFarlane , Edward Rockenstein , Brian Spencer , Eliezer Masliah , Maria Grazia Spillantini , Keith Tan , Andrew Billinton , Tris Vaughan , Iain Chessell , Michael S Perkinton

Characterization and preclinical evaluation of a protease activated receptor 2 (PAR2) monoclonal antibody as a preventive therapy for migraine.

Cephalalgia : an international journal of headache

Avec: Caroline M Kopruszinski , Peter Thornton , Joanne Arnold , Philip Newton , David Lowne , Edita Navratilova , Juliana Swiokla , David W Dodick , Claire Dobson , Ian Gurrell , Iain Patrick Chessell , Frank Porreca

Antibody-oligonucleotide conjugate achieves CNS delivery in animal models for spinal muscular atrophy.

JCI insight

Avec: Suzan M Hammond , Frank Abendroth , Larissa Goli , Jessica Stoodley , Matthew Burrell , George Thom , Ian Gurrell , Nina Ahlskog , Michael J Gait , Matthew Ja Wood , Carl I Webster

Réseau de co-auteurs

George Thom 2 collaborations

Matthew Burrell 2 collaborations

Carl I Webster 2 collaborations

Claire Dobson 2 collaborations

Mei-Mei Tian 1 collaboration

Jon P Hatcher 1 collaboration

Natalia Rodrigo 1 collaboration

Timothy Z Vitalis 1 collaboration

Thomas Abraham 1 collaboration

Wilfred A Jefferies 1 collaboration

Reinhard Gabathuler 1 collaboration

Darren J Schofield 1 collaboration

Lorraine Irving 1 collaboration

Laura Calo 1 collaboration

Anna Bogstedt 1 collaboration

Gareth Rees 1 collaboration

Annalisa Nuccitelli 1 collaboration

Rajesh Narwal 1 collaboration

Marcella Petrone 1 collaboration

Jennifer Roberts 1 collaboration

Lee Brown 1 collaboration

Fiona Cusdin 1 collaboration

Bhupinder Dosanjh 1 collaboration

Christopher Lloyd 1 collaboration

Graham Fraser 1 collaboration

Mary McFarlane 1 collaboration

Edward Rockenstein 1 collaboration

Brian Spencer 1 collaboration

Eliezer Masliah 1 collaboration

Maria Grazia Spillantini 1 collaboration

Keith Tan 1 collaboration

Andrew Billinton 1 collaboration

Tris Vaughan 1 collaboration

Iain Chessell 1 collaboration

Michael S Perkinton 1 collaboration

Caroline M Kopruszinski 1 collaboration

Peter Thornton 1 collaboration

Joanne Arnold 1 collaboration

Philip Newton 1 collaboration

David Lowne 1 collaboration

Edita Navratilova 1 collaboration

Juliana Swiokla 1 collaboration

David W Dodick 1 collaboration

Iain Patrick Chessell 1 collaboration

Frank Porreca 1 collaboration

Suzan M Hammond 1 collaboration

Frank Abendroth 1 collaboration

Larissa Goli 1 collaboration

Jessica Stoodley 1 collaboration

Nina Ahlskog 1 collaboration

Michael J Gait 1 collaboration

Matthew Ja Wood 1 collaboration