Iben Spanggaard

Affiliations

The Phase I Unit, Department of Oncology, Rigshospitalet, Copenhagen, Denmark.

Publications (20)

Copenhagen Prospective Personalized Oncology (CoPPO)-Clinical Utility of Using Molecular Profiling to Select Patients to Phase I Trials.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Ida Viller Tuxen , Kristoffer Staal Rohrberg , Olga Oestrup , Lise Barlebo Ahlborn , Ane Yde Schmidt , Iben Spanggaard , Jane P Hasselby , Eric Santoni-Rugiu , Christina Westmose Yde , Morten Mau-Sørensen , Finn Cilius Nielsen , Ulrik Lassen

Pemigatinib in previously treated solid tumors with activating FGFR1-FGFR3 alterations: phase 2 FIGHT-207 basket trial.

Nature medicine

Avec: Jordi Rodón , Silvia Damian , Muhammad Furqan , Jesús García-Donas , Hiroo Imai , Antoine Italiano , Iben Spanggaard , Makoto Ueno , Tomoya Yokota , Maria Luisa Veronese , Natalia Oliveira , Xin Li , Aidan Gilmartin , Michael Schaffer , Lipika Goyal

New pathogenic germline variants identified in mesothelioma.

Lung cancer (Amsterdam, Netherlands)

Avec: Laila Belcaid , Birgitte Bertelsen , Karin Wadt , Ida Tuxen , Iben Spanggaard , Martin Højgaard , Jens Benn Sørensen , Jesper Ravn , Ulrik Lassen , Finn Cilius Nielsen , Kristoffer Rohrberg , Christina Westmose Yde

ProTarget: a Danish Nationwide Clinical Trial on Targeted Cancer Treatment based on genomic profiling - a national, phase 2, prospective, multi-drug, non-randomized, open-label basket trial.

BMC cancer

Avec: Tina Kringelbach , Martin Højgaard , Kristoffer Rohrberg , Iben Spanggaard , Britt Elmedal Laursen , Morten Ladekarl , Charlotte Aaquist Haslund , Laurine Harsløf , Laila Belcaid , Julie Gehl , Lise Søndergaard , Rikke Løvendahl Eefsen , Karin Holmskov Hansen , Annette Raskov Kodahl , Lars Henrik Jensen , Marianne Ingerslev Holt , Trine Heide Oellegaard , Christina Westmose Yde , Lise Barlebo Ahlborn , Ulrik Lassen

Common phenotypic dynamics of tumor-infiltrating lymphocytes across different histologies upon checkpoint inhibition: impact on clinical outcome.

Cytotherapy

Avec: Vinicius Araujo B de Lima , Annie Borch , Morten Hansen , Arianna Draghi , Iben Spanggaard , Kristoffer Rohrberg , Sine Reker Hadrup , Ulrik Lassen , Inge Marie Svane

[Trends in oncological phase I trials].

Ugeskrift for laeger

Avec: Kristoffer Staal Rohrberg , Camilla Qvortrup , Martin Højgaard , Iben Spanggaard

Application of cell-free DNA for genomic tumor profiling: a feasibility study.

Oncotarget

Avec: Lise B Ahlborn , Kristoffer S Rohrberg , Migle Gabrielaite , Ida V Tuxen , Christina W Yde , Iben Spanggaard , Eric Santoni-Rugiu , Finn C Nielsen , Ulrik Lassen , Morten Mau-Sorensen , Olga Østrup

Selective AKT kinase inhibitor capivasertib in combination with fulvestrant in PTEN-mutant ER-positive metastatic breast cancer.

NPJ breast cancer

Avec: Lillian M Smyth , Gerald Batist , Funda Meric-Bernstam , Peter Kabos , Iben Spanggaard , Ana Lluch , Komal Jhaveri , Andrea Varga , Andrea Wong , Alison M Schram , Helen Ambrose , T Hedley Carr , Elza C de Bruin , Carolina Salinas-Souza , Andrew Foxley , Joana Hauser , Justin P O Lindemann , Rhiannon Maudsley , Robert McEwen , Michele Moschetta , Myria Nikolaou , Gaia Schiavon , Pedram Razavi , Udai Banerji , José Baselga , David M Hyman , Sarat Chandarlapaty

A first-in-human study of the fibroblast activation protein-targeted, 4-1BB agonist RO7122290 in patients with advanced solid tumors.

Science translational medicine

Avec: Ignacio Melero , Tamara Tanos , Mariana Bustamante , Miguel F Sanmamed , Emiliano Calvo , Irene Moreno , Victor Moreno , Tatiana Hernandez , Maria Martinez Garcia , Alejo Rodriguez-Vida , Josep Tabernero , Analia Azaro , Mariano Ponz-Sarvisé , Iben Spanggaard , Kristoffer Rohrberg , Ernesto Guarin , Eveline Nüesch , Iakov I Davydov , Chiahuey Ooi , José Duarte , Evelyne Chesne , Christine McIntyre , Maurizio Ceppi , Marta Cañamero , Oliver Krieter

Neratinib + fulvestrant + trastuzumab for HR-positive, HER2-negative, HER2-mutant metastatic breast cancer: outcomes and biomarker analysis from the SUMMIT trial.

Annals of oncology : official journal of the European Society for Medical Oncology

Avec: K Jhaveri , L D Eli , H Wildiers , S A Hurvitz , A Guerrero-Zotano , N Unni , A Brufsky , H Park , J Waisman , E S Yang , I Spanggaard , S Reid , M E Burkard , S Vinayak , A Prat , M Arnedos , F-C Bidard , S Loi , J Crown , M Bhave , S A Piha-Paul , J M Suga , S Chia , C Saura , J Á Garcia-Saenz , V Gambardella , M J de Miguel , E N Gal-Yam , A Rapael , S M Stemmer , C Ma , A B Hanker , D Ye , J W Goldman , R Bose , L Peterson , J S K Bell , A Frazier , D DiPrimeo , A Wong , C L Arteaga , D B Solit

Open-label, dose-escalation FIGHT-101 study of pemigatinib combined with targeted therapy, chemotherapy, or immunotherapy in patients with advanced malignancies.

ESMO open

Avec: M Saleh , M Barve , V Subbiah , K P Papadopoulos , D Morgensztern , N B Mettu , S Roychowdhury , I Spanggaard , M L Veronese , C Tian , I M Silverman , M Gutierrez

Precision patients: Selection practices and moral pathfinding in experimental oncology.

Sociology of health & illness

Avec: Mie S Dam , Sara Green , Ivana Bogicevic , Line Hillersdal , Iben Spanggaard , Kristoffer S Rohrberg , Mette N Svendsen

Modeling Metastatic Colonization in a Decellularized Organ Scaffold-Based Perfusion Bioreactor.

Advanced healthcare materials

Avec: Maria Rafaeva , Edward R Horton , Adina R D Jensen , Chris D Madsen , Raphael Reuten , Oliver Willacy , Christian B Brøchner , Thomas H Jensen , Kamilla Westarp Zornhagen , Marina Crespo , Dina S Grønseth , Sebastian R Nielsen , Manja Idorn , Per Thor Straten , Kristoffer Rohrberg , Iben Spanggaard , Martin Højgaard , Ulrik Lassen , Janine T Erler , Alejandro E Mayorca-Guiliani

Antitumour activity of neratinib in patients with HER2-mutant advanced biliary tract cancers.

Nature communications

Avec: James J Harding , Sarina A Piha-Paul , Ronak H Shah , Jessica J Murphy , James M Cleary , Geoffrey I Shapiro , David I Quinn , Irene Braña , Victor Moreno , Mitesh Borad , Sherene Loi , Iben Spanggaard , Haeseong Park , James M Ford , Mónica Arnedos , Salomon M Stemmer , Christelle de la Fouchardiere , Christos Fountzilas , Jie Zhang , Daniel DiPrimeo , Casey Savin , S Duygu Selcuklu , Michael F Berger , Lisa D Eli , Funda Meric-Bernstam , Komal Jhaveri , David B Solit , Ghassan K Abou-Alfa

Ugeskrift for laeger

Avec: Bue Ross Agner , Caroline Hasselbalch Riley , Søren Lykke Petersen , Iben Spanggaard , Martin Hutchings , Kristoffer Staal Rohrberg , Martin Højgaard

Trastuzumab deruxtecan in patients with solid tumours harbouring specific activating HER2 mutations (DESTINY-PanTumor01): an international, phase 2 study.

The Lancet. Oncology

Avec: Bob T Li , Funda Meric-Bernstam , Aditya Bardia , Yoichi Naito , Salvatore Siena , Philippe Aftimos , Ian Anderson , Giuseppe Curigliano , Maria de Miguel , Maitri Kalra , Do-Youn Oh , Joon Oh Park , Sophie Postel-Vinay , Sun Young Rha , Taroh Satoh , Iben Spanggaard , Flavia Michelini , Ann Smith , Karime Kalil Machado , Cristina Saura , Auteur inconnu

First-in-human phase 1 dose-escalation study of CAN04, a first-in-class interleukin-1 receptor accessory protein (IL1RAP) antibody in patients with solid tumours.

British journal of cancer

Avec: Debbie Robbrecht , Christiane Jungels , Morten Mau Sorensen , Iben Spanggaard , Ferry Eskens , Signe Ø Fretland , Tormod Kyrre Guren , Philippe Aftimos , David Liberg , Christer Svedman , Lars Thorsson , Neeltje Steeghs , Ahmad Awada

Immune Cell Profiling of Peripheral Blood as Signature for Response During Checkpoint Inhibition Across Cancer Types.

Frontiers in oncology

Avec: Vinicius Araujo B de Lima , Morten Hansen , Iben Spanggaard , Kristoffer Rohrberg , Sine Reker Hadrup , Ulrik Lassen , Inge Marie Svane

Targeting HER2-mutant metastatic cervical cancer with neratinib: Final results from the phase 2 SUMMIT basket trial.

Gynecologic oncology

Avec: Claire F Friedman , Anishka D'Souza , Diana Bello Roufai , Anna V Tinker , Maria de Miguel , Valentina Gambardella , Jonathan Goldman , Sherene Loi , Michelle E Melisko , Ana Oaknin , Iben Spanggaard , Geoffrey I Shapiro , Adam C ElNaggar , Stefano Panni , Vignesh Ravichandran , Aimee L Frazier , Daniel DiPrimeo , Lisa D Eli , David B Solit

Extensive genomic analysis in patients with

Acta oncologica (Stockholm, Sweden)

Avec: Ida Christine Jacobsen , Iben Spanggaard , Martin Højgaard , Laïla Belcaid , Camilla Qvortrup , Christina Westmose Yde , Ane Yde Schmidt , Finn Cilius Nielsen , Gro Linno Willemoe , Mikkel Seidelin Dam , Ulrik Lassen , Kristoffer Staal Rohrberg

Réseau de co-auteurs

Ulrik Lassen 8 collaborations

Martin Højgaard 6 collaborations

Kristoffer Rohrberg 6 collaborations

Kristoffer Staal Rohrberg 4 collaborations

Christina Westmose Yde 4 collaborations

Finn Cilius Nielsen 3 collaborations

Funda Meric-Bernstam 3 collaborations

Lise Barlebo Ahlborn 2 collaborations

Ane Yde Schmidt 2 collaborations

Eric Santoni-Rugiu 2 collaborations

Laila Belcaid 2 collaborations

Vinicius Araujo B de Lima 2 collaborations

Morten Hansen 2 collaborations

Sine Reker Hadrup 2 collaborations

Inge Marie Svane 2 collaborations

Camilla Qvortrup 2 collaborations

Kristoffer S Rohrberg 2 collaborations

Komal Jhaveri 2 collaborations

Victor Moreno 2 collaborations

I Spanggaard 2 collaborations

Geoffrey I Shapiro 2 collaborations

Sherene Loi 2 collaborations

Daniel DiPrimeo 2 collaborations

Lisa D Eli 2 collaborations

David B Solit 2 collaborations

Philippe Aftimos 2 collaborations

Maria de Miguel 2 collaborations

Ida Viller Tuxen 1 collaboration

Olga Oestrup 1 collaboration

Jane P Hasselby 1 collaboration

Morten Mau-Sørensen 1 collaboration

Jordi Rodón 1 collaboration

Silvia Damian 1 collaboration

Muhammad Furqan 1 collaboration

Jesús García-Donas 1 collaboration

Hiroo Imai 1 collaboration

Antoine Italiano 1 collaboration

Makoto Ueno 1 collaboration

Tomoya Yokota 1 collaboration

Maria Luisa Veronese 1 collaboration

Natalia Oliveira 1 collaboration

Xin Li 1 collaboration

Aidan Gilmartin 1 collaboration

Michael Schaffer 1 collaboration

Lipika Goyal 1 collaboration

Birgitte Bertelsen 1 collaboration

Karin Wadt 1 collaboration

Ida Tuxen 1 collaboration

Jens Benn Sørensen 1 collaboration

Jesper Ravn 1 collaboration

Tina Kringelbach 1 collaboration

Britt Elmedal Laursen 1 collaboration

Morten Ladekarl 1 collaboration

Charlotte Aaquist Haslund 1 collaboration

Laurine Harsløf 1 collaboration

Julie Gehl 1 collaboration

Lise Søndergaard 1 collaboration

Rikke Løvendahl Eefsen 1 collaboration

Karin Holmskov Hansen 1 collaboration

Annette Raskov Kodahl 1 collaboration

Lars Henrik Jensen 1 collaboration

Marianne Ingerslev Holt 1 collaboration

Trine Heide Oellegaard 1 collaboration

Annie Borch 1 collaboration

Arianna Draghi 1 collaboration

Lise B Ahlborn 1 collaboration

Migle Gabrielaite 1 collaboration

Ida V Tuxen 1 collaboration

Christina W Yde 1 collaboration

Finn C Nielsen 1 collaboration

Morten Mau-Sorensen 1 collaboration

Olga Østrup 1 collaboration

Lillian M Smyth 1 collaboration

Gerald Batist 1 collaboration

Peter Kabos 1 collaboration

Ana Lluch 1 collaboration

Andrea Varga 1 collaboration

Andrea Wong 1 collaboration

Alison M Schram 1 collaboration

Helen Ambrose 1 collaboration

T Hedley Carr 1 collaboration

Elza C de Bruin 1 collaboration

Carolina Salinas-Souza 1 collaboration

Andrew Foxley 1 collaboration

Joana Hauser 1 collaboration

Justin P O Lindemann 1 collaboration

Rhiannon Maudsley 1 collaboration

Robert McEwen 1 collaboration

Michele Moschetta 1 collaboration

Myria Nikolaou 1 collaboration

Gaia Schiavon 1 collaboration

Pedram Razavi 1 collaboration

Udai Banerji 1 collaboration

José Baselga 1 collaboration

David M Hyman 1 collaboration

Sarat Chandarlapaty 1 collaboration

Ignacio Melero 1 collaboration

Tamara Tanos 1 collaboration

Mariana Bustamante 1 collaboration

Miguel F Sanmamed 1 collaboration

Emiliano Calvo 1 collaboration

Irene Moreno 1 collaboration

Tatiana Hernandez 1 collaboration

Maria Martinez Garcia 1 collaboration

Alejo Rodriguez-Vida 1 collaboration

Josep Tabernero 1 collaboration

Analia Azaro 1 collaboration

Mariano Ponz-Sarvisé 1 collaboration

Ernesto Guarin 1 collaboration

Eveline Nüesch 1 collaboration

Iakov I Davydov 1 collaboration

Chiahuey Ooi 1 collaboration

José Duarte 1 collaboration

Evelyne Chesne 1 collaboration

Christine McIntyre 1 collaboration

Maurizio Ceppi 1 collaboration

Marta Cañamero 1 collaboration

Oliver Krieter 1 collaboration

K Jhaveri 1 collaboration

L D Eli 1 collaboration

H Wildiers 1 collaboration

S A Hurvitz 1 collaboration

A Guerrero-Zotano 1 collaboration

N Unni 1 collaboration

A Brufsky 1 collaboration

H Park 1 collaboration

J Waisman 1 collaboration

E S Yang 1 collaboration

S Reid 1 collaboration

M E Burkard 1 collaboration

S Vinayak 1 collaboration

A Prat 1 collaboration

M Arnedos 1 collaboration

F-C Bidard 1 collaboration

S Loi 1 collaboration

J Crown 1 collaboration

M Bhave 1 collaboration

S A Piha-Paul 1 collaboration

J M Suga 1 collaboration

S Chia 1 collaboration

C Saura 1 collaboration

J Á Garcia-Saenz 1 collaboration

V Gambardella 1 collaboration

M J de Miguel 1 collaboration

E N Gal-Yam 1 collaboration

A Rapael 1 collaboration

S M Stemmer 1 collaboration

C Ma 1 collaboration

A B Hanker 1 collaboration

D Ye 1 collaboration

J W Goldman 1 collaboration

R Bose 1 collaboration

L Peterson 1 collaboration

J S K Bell 1 collaboration

A Frazier 1 collaboration

D DiPrimeo 1 collaboration

A Wong 1 collaboration

C L Arteaga 1 collaboration

D B Solit 1 collaboration

M Saleh 1 collaboration

M Barve 1 collaboration

V Subbiah 1 collaboration

K P Papadopoulos 1 collaboration

D Morgensztern 1 collaboration

N B Mettu 1 collaboration

S Roychowdhury 1 collaboration

M L Veronese 1 collaboration

C Tian 1 collaboration

I M Silverman 1 collaboration

M Gutierrez 1 collaboration

Mie S Dam 1 collaboration

Sara Green 1 collaboration

Ivana Bogicevic 1 collaboration

Line Hillersdal 1 collaboration

Mette N Svendsen 1 collaboration

Maria Rafaeva 1 collaboration

Edward R Horton 1 collaboration

Adina R D Jensen 1 collaboration

Chris D Madsen 1 collaboration

Raphael Reuten 1 collaboration

Oliver Willacy 1 collaboration

Christian B Brøchner 1 collaboration

Thomas H Jensen 1 collaboration

Kamilla Westarp Zornhagen 1 collaboration

Marina Crespo 1 collaboration

Dina S Grønseth 1 collaboration

Sebastian R Nielsen 1 collaboration

Manja Idorn 1 collaboration

Per Thor Straten 1 collaboration

Janine T Erler 1 collaboration

Alejandro E Mayorca-Guiliani 1 collaboration

James J Harding 1 collaboration

Sarina A Piha-Paul 1 collaboration

Ronak H Shah 1 collaboration

Jessica J Murphy 1 collaboration

James M Cleary 1 collaboration

David I Quinn 1 collaboration

Irene Braña 1 collaboration

Mitesh Borad 1 collaboration

Haeseong Park 1 collaboration

James M Ford 1 collaboration

Mónica Arnedos 1 collaboration

Salomon M Stemmer 1 collaboration

Christelle de la Fouchardiere 1 collaboration

Christos Fountzilas 1 collaboration

Jie Zhang 1 collaboration

Casey Savin 1 collaboration

S Duygu Selcuklu 1 collaboration

Michael F Berger 1 collaboration

Ghassan K Abou-Alfa 1 collaboration

Bue Ross Agner 1 collaboration

Caroline Hasselbalch Riley 1 collaboration

Søren Lykke Petersen 1 collaboration

Martin Hutchings 1 collaboration

Bob T Li 1 collaboration

Aditya Bardia 1 collaboration

Yoichi Naito 1 collaboration

Salvatore Siena 1 collaboration

Ian Anderson 1 collaboration

Giuseppe Curigliano 1 collaboration

Maitri Kalra 1 collaboration

Do-Youn Oh 1 collaboration

Joon Oh Park 1 collaboration

Sophie Postel-Vinay 1 collaboration

Sun Young Rha 1 collaboration

Taroh Satoh 1 collaboration

Flavia Michelini 1 collaboration

Ann Smith 1 collaboration

Karime Kalil Machado 1 collaboration

Cristina Saura 1 collaboration

None None 1 collaboration

Debbie Robbrecht 1 collaboration

Christiane Jungels 1 collaboration

Morten Mau Sorensen 1 collaboration

Ferry Eskens 1 collaboration

Signe Ø Fretland 1 collaboration

Tormod Kyrre Guren 1 collaboration

David Liberg 1 collaboration

Christer Svedman 1 collaboration

Lars Thorsson 1 collaboration

Neeltje Steeghs 1 collaboration

Ahmad Awada 1 collaboration

Claire F Friedman 1 collaboration

Anishka D'Souza 1 collaboration

Diana Bello Roufai 1 collaboration

Anna V Tinker 1 collaboration

Valentina Gambardella 1 collaboration

Jonathan Goldman 1 collaboration

Michelle E Melisko 1 collaboration

Ana Oaknin 1 collaboration

Adam C ElNaggar 1 collaboration

Stefano Panni 1 collaboration

Vignesh Ravichandran 1 collaboration

Aimee L Frazier 1 collaboration

Ida Christine Jacobsen 1 collaboration

Laïla Belcaid 1 collaboration

Gro Linno Willemoe 1 collaboration

Mikkel Seidelin Dam 1 collaboration