Jason Baardsnes

Affiliations

Human Health Therapeutics Portfolio, NRC-CNRC , Montreal, QC, Canada.

Publications (14)

AlbuCORE: an albumin-based molecular scaffold for multivalent biologics design.

mAbs

Avec: Mario Sanches , Igor D'Angelo , Maria Jaramillo , Jason Baardsnes , John Zwaagstra , Joe Schrag , Ian Schoenhofen , Mauro Acchione , Sam Lawn , Grant Wickman , Nina Weisser , David K Y Poon , Gordon Ng , Surjit Dixit

New soluble angiopoietin analog of Hepta-ANG1 prevents pathological vascular leakage.

Biotechnology and bioengineering

Avec: Pan Liu , Michael Ryczko , Xinfang Xie , Jason Baardsnes , Simon Lord-Dufour , Yves Duroche , Emily Anne Hicks , Aftab Taiyab , Heather Sheardown , Susan E Quaggin , Jing Jin

Structure-based engineering of pH-dependent antibody binding for selective targeting of solid-tumor microenvironment.

mAbs

Avec: Traian Sulea , Nazanin Rohani , Jason Baardsnes , Christopher R Corbeil , Christophe Deprez , Yuneivy Cepero-Donates , Alma Robert , Joseph D Schrag , Marie Parat , Mélanie Duchesne , Maria L Jaramillo , Enrico O Purisima , John C Zwaagstra

Redesigning an antibody H3 loop by virtual screening of a small library of human germline-derived sequences.

Scientific reports

Avec: Christopher R Corbeil , Mahder Seifu Manenda , Traian Sulea , Jason Baardsnes , Marie-Ève Picard , Hervé Hogues , Francis Gaudreault , Christophe Deprez , Rong Shi , Enrico O Purisima

Exploring rigid-backbone protein docking in biologics discovery: a test using the DARPin scaffold.

Frontiers in molecular biosciences

Avec: Francis Gaudreault , Jason Baardsnes , Yuliya Martynova , Aurore Dachon , Hervé Hogues , Christopher R Corbeil , Enrico O Purisima , Mélanie Arbour , Traian Sulea

Binding symmetry and surface flexibility mediate antibody self-association.

mAbs

Avec: Joseph D Schrag , Marie-Ève Picard , Francis Gaudreault , Louis-Patrick Gagnon , Jason Baardsnes , Mahder S Manenda , Joey Sheff , Christophe Deprez , Cassio Baptista , Hervé Hogues , John F Kelly , Enrico O Purisima , Rong Shi , Traian Sulea

A CHO stable pool production platform for rapid clinical development of trimeric SARS-CoV-2 spike subunit vaccine antigens.

Biotechnology and bioengineering

Avec: Simon Joubert , Matthew Stuible , Simon Lord-Dufour , Linda Lamoureux , François Vaillancourt , Sylvie Perret , Manon Ouimet , Alex Pelletier , Louis Bisson , Rohan Mahimkar , Phuong Lan Pham , Helene L Ecuyer-Coelho , Marjolaine Roy , Robert Voyer , Jason Baardsnes , Janelle Sauvageau , Frank St-Michael , Anna Robotham , John Kelly , Andrea Acel , Joseph D Schrag , Majida El Bakkouri , Yves Durocher

TNX-1500, a crystallizable fragment-modified anti-CD154 antibody, prolongs nonhuman primate renal allograft survival.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Avec: Grace Lassiter , Ryo Otsuka , Takayuki Hirose , Ivy Rosales , Ahmad Karadagi , Toshihide Tomosugi , Abbas Dehnadi , Hang Lee , Robert B Colvin , Jason Baardsnes , Anna Moraitis , Emma E Smith , Zahida Ali , Phil Berhe , Andrew Mulder , Bernd Meibohm , Bruce Daugherty , Siobhan Fogarty , Richard N Pierson , Seth Lederman , Tatsuo Kawai

Binding and functional profiling of antibody mutants guides selection of optimal candidates as antibody drug conjugates.

PloS one

Avec: John C Zwaagstra , Traian Sulea , Jason Baardsnes , Stevo Radinovic , Yuneivy Cepero-Donates , Alma Robert , Maureen D O'Connor-McCourt , Ilia A Tikhomirov , Maria Luz Jaramillo

Production of afucosylated antibodies in CHO cells by coexpression of an anti-FUT8 intrabody.

Biotechnology and bioengineering

Avec: Simon Joubert , Julie Guimond , Sylvie Perret , Félix Malenfant , S Mehdy Elahi , Anne Marcil , Marie Parat , Michel Gilbert , Anne E G Lenferink , Jason Baardsnes , Yves Durocher

An anti-HER2 biparatopic antibody that induces unique HER2 clustering and complement-dependent cytotoxicity.

Nature communications

Avec: Nina E Weisser , Mario Sanches , Eric Escobar-Cabrera , Jason O'Toole , Elizabeth Whalen , Peter W Y Chan , Grant Wickman , Libin Abraham , Kate Choi , Bryant Harbourne , Antonios Samiotakis , Andrea Hernández Rojas , Gesa Volkers , Jodi Wong , Claire E Atkinson , Jason Baardsnes , Liam J Worrall , Duncan Browman , Emma E Smith , Priya Baichoo , Chi Wing Cheng , Joy Guedia , Sohyeong Kang , Abhishek Mukhopadhyay , Lisa Newhook , Anders Ohrn , Prajwal Raghunatha , Matteo Zago-Schmitt , Joseph D Schrag , Joel Smith , Patricia Zwierzchowski , Joshua M Scurll , Vincent Fung , Sonia Black , Natalie C J Strynadka , Michael R Gold , Leonard G Presta , Gordon Ng , Surjit Dixit

Structure-based dual affinity optimization of a SARS-CoV-1/2 cross-reactive single-domain antibody.

PloS one

Avec: Traian Sulea , Jason Baardsnes , Matthew Stuible , Nazanin Rohani , Anh Tran , Marie Parat , Yuneivy Cepero Donates , Mélanie Duchesne , Pierre Plante , Guneet Kour , Yves Durocher

Tuning the immune response: sulfated archaeal glycolipid archaeosomes as an effective vaccine adjuvant for induction of humoral and cell-mediated immunity towards the SARS-CoV-2 Omicron variant of concern.

Frontiers in immunology

Avec: Tyler M Renner , Bassel Akache , Matthew Stuible , Nazanin Rohani , Yuneivy Cepero-Donates , Lise Deschatelets , Renu Dudani , Blair A Harrison , Jason Baardsnes , Izel Koyuturk , Jennifer J Hill , Usha D Hemraz , Sophie Régnier , Anne E G Lenferink , Yves Durocher , Michael J McCluskie

SARS-CoV-2S-Protein-Ace2 Binding Analysis Using Surface Plasmon Resonance.

Methods in molecular biology (Clifton, N.J.)

Avec: Jason Baardsnes , Béatrice Paul-Roc

Réseau de co-auteurs

Traian Sulea 6 collaborations

Joseph D Schrag 4 collaborations

Enrico O Purisima 4 collaborations

Yves Durocher 4 collaborations

Nazanin Rohani 3 collaborations

Christopher R Corbeil 3 collaborations

Christophe Deprez 3 collaborations

Yuneivy Cepero-Donates 3 collaborations

Marie Parat 3 collaborations

Hervé Hogues 3 collaborations

Francis Gaudreault 3 collaborations

Matthew Stuible 3 collaborations

Mario Sanches 2 collaborations

Grant Wickman 2 collaborations

Gordon Ng 2 collaborations

Surjit Dixit 2 collaborations

Simon Lord-Dufour 2 collaborations

Alma Robert 2 collaborations

Mélanie Duchesne 2 collaborations

John C Zwaagstra 2 collaborations

Marie-Ève Picard 2 collaborations

Rong Shi 2 collaborations

Simon Joubert 2 collaborations

Sylvie Perret 2 collaborations

Emma E Smith 2 collaborations

Anne E G Lenferink 2 collaborations

Igor D'Angelo 1 collaboration

Maria Jaramillo 1 collaboration

John Zwaagstra 1 collaboration

Joe Schrag 1 collaboration

Ian Schoenhofen 1 collaboration

Mauro Acchione 1 collaboration

Sam Lawn 1 collaboration

Nina Weisser 1 collaboration

David K Y Poon 1 collaboration

Pan Liu 1 collaboration

Michael Ryczko 1 collaboration

Xinfang Xie 1 collaboration

Yves Duroche 1 collaboration

Emily Anne Hicks 1 collaboration

Aftab Taiyab 1 collaboration

Heather Sheardown 1 collaboration

Susan E Quaggin 1 collaboration

Jing Jin 1 collaboration

Maria L Jaramillo 1 collaboration

Mahder Seifu Manenda 1 collaboration

Yuliya Martynova 1 collaboration

Aurore Dachon 1 collaboration

Mélanie Arbour 1 collaboration

Louis-Patrick Gagnon 1 collaboration

Mahder S Manenda 1 collaboration

Joey Sheff 1 collaboration

Cassio Baptista 1 collaboration

John F Kelly 1 collaboration

Linda Lamoureux 1 collaboration

François Vaillancourt 1 collaboration

Manon Ouimet 1 collaboration

Alex Pelletier 1 collaboration

Louis Bisson 1 collaboration

Rohan Mahimkar 1 collaboration

Phuong Lan Pham 1 collaboration

Helene L Ecuyer-Coelho 1 collaboration

Marjolaine Roy 1 collaboration

Robert Voyer 1 collaboration

Janelle Sauvageau 1 collaboration

Frank St-Michael 1 collaboration

Anna Robotham 1 collaboration

John Kelly 1 collaboration

Andrea Acel 1 collaboration

Majida El Bakkouri 1 collaboration

Grace Lassiter 1 collaboration

Ryo Otsuka 1 collaboration

Takayuki Hirose 1 collaboration

Ivy Rosales 1 collaboration

Ahmad Karadagi 1 collaboration

Toshihide Tomosugi 1 collaboration

Abbas Dehnadi 1 collaboration

Hang Lee 1 collaboration

Robert B Colvin 1 collaboration

Anna Moraitis 1 collaboration

Zahida Ali 1 collaboration

Phil Berhe 1 collaboration

Andrew Mulder 1 collaboration

Bernd Meibohm 1 collaboration

Bruce Daugherty 1 collaboration

Siobhan Fogarty 1 collaboration

Richard N Pierson 1 collaboration

Seth Lederman 1 collaboration

Tatsuo Kawai 1 collaboration

Stevo Radinovic 1 collaboration

Maureen D O'Connor-McCourt 1 collaboration

Ilia A Tikhomirov 1 collaboration

Maria Luz Jaramillo 1 collaboration

Julie Guimond 1 collaboration

Félix Malenfant 1 collaboration

S Mehdy Elahi 1 collaboration

Anne Marcil 1 collaboration

Michel Gilbert 1 collaboration

Nina E Weisser 1 collaboration

Eric Escobar-Cabrera 1 collaboration

Jason O'Toole 1 collaboration

Elizabeth Whalen 1 collaboration

Peter W Y Chan 1 collaboration

Libin Abraham 1 collaboration

Kate Choi 1 collaboration

Bryant Harbourne 1 collaboration

Antonios Samiotakis 1 collaboration

Andrea Hernández Rojas 1 collaboration

Gesa Volkers 1 collaboration

Jodi Wong 1 collaboration

Claire E Atkinson 1 collaboration

Liam J Worrall 1 collaboration

Duncan Browman 1 collaboration

Priya Baichoo 1 collaboration

Chi Wing Cheng 1 collaboration

Joy Guedia 1 collaboration

Sohyeong Kang 1 collaboration

Abhishek Mukhopadhyay 1 collaboration

Lisa Newhook 1 collaboration

Anders Ohrn 1 collaboration

Prajwal Raghunatha 1 collaboration

Matteo Zago-Schmitt 1 collaboration

Joel Smith 1 collaboration

Patricia Zwierzchowski 1 collaboration

Joshua M Scurll 1 collaboration

Vincent Fung 1 collaboration

Sonia Black 1 collaboration

Natalie C J Strynadka 1 collaboration

Michael R Gold 1 collaboration

Leonard G Presta 1 collaboration

Anh Tran 1 collaboration

Yuneivy Cepero Donates 1 collaboration

Pierre Plante 1 collaboration

Guneet Kour 1 collaboration

Tyler M Renner 1 collaboration

Bassel Akache 1 collaboration

Lise Deschatelets 1 collaboration

Renu Dudani 1 collaboration

Blair A Harrison 1 collaboration

Izel Koyuturk 1 collaboration

Jennifer J Hill 1 collaboration

Usha D Hemraz 1 collaboration

Sophie Régnier 1 collaboration

Michael J McCluskie 1 collaboration

Béatrice Paul-Roc 1 collaboration