Jaya Sangodkar

Affiliations

Division of Genetic Medicine, Department of Medicine, The University of Michigan, Ann Arbor, Michigan, United States of America.

Publications (9)

The SRG rat, a Sprague-Dawley Rag2/Il2rg double-knockout validated for human tumor oncology studies.

PloS one

Avec: Fallon K Noto , Jaya Sangodkar , Bisoye Towobola Adedeji , Sam Moody , Christopher B McClain , Ming Tong , Eric Ostertag , Jack Crawford , Xiaohua Gao , Lauren Hurst , Caitlin M O'Connor , Erika N Hanson , Sudeh Izadmehr , Rita Tohmé , Jyothsna Narla , Kristin LeSueur , Kajari Bhattacharya , Amit Rupani , Marwan K Tayeh , Jeffrey W Innis , Matthew D Galsky , B Mark Evers , Analisa DiFeo , Goutham Narla , Tseten Y Jamling

Targeting PP2A in cancer: Combination therapies.

Biochimica et biophysica acta. Molecular cell research

Avec: Sahar Mazhar , Sarah E Taylor , Jaya Sangodkar , Goutham Narla

Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells.

Cancer cell

Avec: Garry L Coles , Sandra Cristea , James T Webber , Rebecca S Levin , Steven M Moss , Andy He , Jaya Sangodkar , Yeonjoo C Hwang , Julia Arand , Alexandros P Drainas , Nancie A Mooney , Janos Demeter , Jessica N Spradlin , Brandon Mauch , Vicky Le , Yan Ting Shue , Julie H Ko , Myung Chang Lee , Christina Kong , Daniel K Nomura , Michael Ohlmeyer , Danielle L Swaney , Nevan J Krogan , Peter K Jackson , Goutham Narla , John D Gordan , Kevan M Shokat , Julien Sage

Protein phosphatase 2A activation as a therapeutic strategy for managing MYC-driven cancers.

The Journal of biological chemistry

Avec: Caroline C Farrington , Eric Yuan , Sahar Mazhar , Sudeh Izadmehr , Lauren Hurst , Brittany L Allen-Petersen , Mahnaz Janghorban , Eric Chung , Grace Wolczanski , Matthew Galsky , Rosalie Sears , Jaya Sangodkar , Goutham Narla

Targeting Ribonucleotide Reductase Induces Synthetic Lethality in PP2A-Deficient Uterine Serous Carcinoma.

Cancer research

Avec: Caitlin M O'Connor , Sarah E Taylor , Kathryn M Miller , Lauren Hurst , Terrance J Haanen , Tahra K Suhan , Kaitlin P Zawacki , Fallon K Noto , Jonida Trako , Arathi Mohan , Jaya Sangodkar , Dmitriy Zamarin , Analisa DiFeo , Goutham Narla

Loss of LCMT1 and biased protein phosphatase 2A heterotrimerization drive prostate cancer progression and therapy resistance.

Nature communications

Avec: Reyaz Ur Rasool , Caitlin M O'Connor , Chandan Kanta Das , Mohammed Alhusayan , Brijesh Kumar Verma , Sehbanul Islam , Ingrid E Frohner , Qu Deng , Erick Mitchell-Velasquez , Jaya Sangodkar , Aqila Ahmed , Sarah Linauer , Ingrid Mudrak , Jessica Rainey , Kaitlin P Zawacki , Tahra K Suhan , Catherine G Callahan , Ryan Rebernick , Ramakrishnan Natesan , Javed Siddiqui , Guido Sauter , Dafydd Thomas , Shaomeng Wang , Derek J Taylor , Ronald Simon , Marcin Cieslik , Arul M Chinnaiyan , Luca Busino , Egon Ogris , Goutham Narla , Irfan A Asangani

Inactivation of PP2A by a recurrent mutation drives resistance to MEK inhibitors.

Oncogene

Avec: Caitlin M O'Connor , Daniel Leonard , Danica Wiredja , Rita A Avelar , Zhizhi Wang , Daniela Schlatzer , Benjamin Bryson , Eesha Tokala , Sarah E Taylor , Aditya Upadhyay , Jaya Sangodkar , Anne-Claude Gingras , Jukka Westermarck , Wenqing Xu , Analisa DiFeo , David L Brautigan , Shozeb Haider , Mark Jackson , Goutham Narla

Direct activation of PP2A for the treatment of tyrosine kinase inhibitor-resistant lung adenocarcinoma.

JCI insight

Avec: Rita Tohmé , Sudeh Izadmehr , Sai Gandhe , Giancarlo Tabaro , Sanjay Vallabhaneni , Ava Thomas , Neal Vasireddi , Neil S Dhawan , Avi Ma'ayan , Neelesh Sharma , Matthew D Galsky , Michael Ohlmeyer , Jaya Sangodkar , Goutham Narla

The Highly Recurrent PP2A Aα-Subunit Mutation P179R Alters Protein Structure and Impairs PP2A Enzyme Function to Promote Endometrial Tumorigenesis.

Cancer research

Avec: Sarah E Taylor , Caitlin M O'Connor , Zhizhi Wang , Guobo Shen , Haichi Song , Daniel Leonard , Jaya Sangodkar , Corinne LaVasseur , Stefanie Avril , Steven Waggoner , Kristine Zanotti , Amy J Armstrong , Christa Nagel , Kimberly Resnick , Sareena Singh , Mark W Jackson , Wenqing Xu , Shozeb Haider , Analisa DiFeo , Goutham Narla

Réseau de co-auteurs

Goutham Narla 9 collaborations

Caitlin M O'Connor 5 collaborations

Analisa DiFeo 4 collaborations

Sarah E Taylor 4 collaborations

Lauren Hurst 3 collaborations

Sudeh Izadmehr 3 collaborations

Fallon K Noto 2 collaborations

Rita Tohmé 2 collaborations

Matthew D Galsky 2 collaborations

Sahar Mazhar 2 collaborations

Michael Ohlmeyer 2 collaborations

Tahra K Suhan 2 collaborations

Kaitlin P Zawacki 2 collaborations

Daniel Leonard 2 collaborations

Zhizhi Wang 2 collaborations

Wenqing Xu 2 collaborations

Shozeb Haider 2 collaborations

Bisoye Towobola Adedeji 1 collaboration

Sam Moody 1 collaboration

Christopher B McClain 1 collaboration

Ming Tong 1 collaboration

Eric Ostertag 1 collaboration

Jack Crawford 1 collaboration

Xiaohua Gao 1 collaboration

Erika N Hanson 1 collaboration

Jyothsna Narla 1 collaboration

Kristin LeSueur 1 collaboration

Kajari Bhattacharya 1 collaboration

Amit Rupani 1 collaboration

Marwan K Tayeh 1 collaboration

Jeffrey W Innis 1 collaboration

B Mark Evers 1 collaboration

Tseten Y Jamling 1 collaboration

Garry L Coles 1 collaboration

Sandra Cristea 1 collaboration

James T Webber 1 collaboration

Rebecca S Levin 1 collaboration

Steven M Moss 1 collaboration

Andy He 1 collaboration

Yeonjoo C Hwang 1 collaboration

Julia Arand 1 collaboration

Alexandros P Drainas 1 collaboration

Nancie A Mooney 1 collaboration

Janos Demeter 1 collaboration

Jessica N Spradlin 1 collaboration

Brandon Mauch 1 collaboration

Vicky Le 1 collaboration

Yan Ting Shue 1 collaboration

Julie H Ko 1 collaboration

Myung Chang Lee 1 collaboration

Christina Kong 1 collaboration

Daniel K Nomura 1 collaboration

Danielle L Swaney 1 collaboration

Nevan J Krogan 1 collaboration

Peter K Jackson 1 collaboration

John D Gordan 1 collaboration

Kevan M Shokat 1 collaboration

Julien Sage 1 collaboration

Caroline C Farrington 1 collaboration

Eric Yuan 1 collaboration

Brittany L Allen-Petersen 1 collaboration

Mahnaz Janghorban 1 collaboration

Eric Chung 1 collaboration

Grace Wolczanski 1 collaboration

Matthew Galsky 1 collaboration

Rosalie Sears 1 collaboration

Kathryn M Miller 1 collaboration

Terrance J Haanen 1 collaboration

Jonida Trako 1 collaboration

Arathi Mohan 1 collaboration

Dmitriy Zamarin 1 collaboration

Reyaz Ur Rasool 1 collaboration

Chandan Kanta Das 1 collaboration

Mohammed Alhusayan 1 collaboration

Brijesh Kumar Verma 1 collaboration

Sehbanul Islam 1 collaboration

Ingrid E Frohner 1 collaboration

Qu Deng 1 collaboration

Erick Mitchell-Velasquez 1 collaboration

Aqila Ahmed 1 collaboration

Sarah Linauer 1 collaboration

Ingrid Mudrak 1 collaboration

Jessica Rainey 1 collaboration

Catherine G Callahan 1 collaboration

Ryan Rebernick 1 collaboration

Ramakrishnan Natesan 1 collaboration

Javed Siddiqui 1 collaboration

Guido Sauter 1 collaboration

Dafydd Thomas 1 collaboration

Shaomeng Wang 1 collaboration

Derek J Taylor 1 collaboration

Ronald Simon 1 collaboration

Marcin Cieslik 1 collaboration

Arul M Chinnaiyan 1 collaboration

Luca Busino 1 collaboration

Egon Ogris 1 collaboration

Irfan A Asangani 1 collaboration

Danica Wiredja 1 collaboration

Rita A Avelar 1 collaboration

Daniela Schlatzer 1 collaboration

Benjamin Bryson 1 collaboration

Eesha Tokala 1 collaboration

Aditya Upadhyay 1 collaboration

Anne-Claude Gingras 1 collaboration

Jukka Westermarck 1 collaboration

David L Brautigan 1 collaboration

Mark Jackson 1 collaboration

Sai Gandhe 1 collaboration

Giancarlo Tabaro 1 collaboration

Sanjay Vallabhaneni 1 collaboration

Ava Thomas 1 collaboration

Neal Vasireddi 1 collaboration

Neil S Dhawan 1 collaboration

Avi Ma'ayan 1 collaboration

Neelesh Sharma 1 collaboration

Guobo Shen 1 collaboration

Haichi Song 1 collaboration

Corinne LaVasseur 1 collaboration

Stefanie Avril 1 collaboration

Steven Waggoner 1 collaboration

Kristine Zanotti 1 collaboration

Amy J Armstrong 1 collaboration

Christa Nagel 1 collaboration

Kimberly Resnick 1 collaboration

Sareena Singh 1 collaboration

Mark W Jackson 1 collaboration