Jeevan B Gc

Affiliations

College of Pharmacy and Pharmaceutical Sciences, Washington State University, Spokane, Washington.

Publications (10)

Does the Lipid Bilayer Orchestrate Access and Binding of Ligands to Transmembrane Orthosteric/Allosteric Sites of G Protein-Coupled Receptors?

Molecular pharmacology

Avec: Christopher T Szlenk , Jeevan B Gc , Senthil Natesan

Mechanisms of Herb-Drug Interactions Involving Cinnamon and CYP2A6: Focus on Time-Dependent Inhibition by Cinnamaldehyde and 2-Methoxycinnamaldehyde.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Michael J Espiritu , Justin Chen , Jaydeep Yadav , Michael Larkin , Robert D Pelletier , Jeannine M Chan , Jeevan B Gc , Senthil Natesan , John P Harrelson

Membrane-Facilitated Receptor Access and Binding Mechanisms of Long-Acting

Molecular pharmacology

Avec: Christopher T Szlenk , Jeevan B Gc , Senthil Natesan

Application of Generative Artificial Intelligence in Predicting Membrane Partitioning of Drugs: Combining Denoising Diffusion Probabilistic Models and MD Simulations Reduces the Computational Cost to One-Third.

Journal of chemical theory and computation

Avec: Peter Obi , Jeevan B Gc , Charles Mariasoosai , Ayobami Diyaolu , Senthil Natesan

Molecular Dynamics Simulations Provide Insight into the Loading Efficiency of Proresolving Lipid Mediators Resolvin D1 and D2 in Cell Membrane-Derived Nanovesicles.

Molecular pharmaceutics

Avec: Jeevan B Gc , Christopher T Szlenk , Jin Gao , Xinyue Dong , Zhenjia Wang , Senthil Natesan

RRM1 variants cause a mitochondrial DNA maintenance disorder via impaired de novo nucleotide synthesis.

The Journal of clinical investigation

Avec: Jonathan Shintaku , Wolfgang M Pernice , Wafaa Eyaid , Jeevan B Gc , Zuben P Brown , Marti Juanola-Falgarona , Javier Torres-Torronteras , Ewen W Sommerville , Debby Mei Hellebrekers , Emma L Blakely , Alan Donaldson , Ingrid van de Laar , Cheng-Shiun Leu , Ramon Marti , Joachim Frank , Kurenai Tanji , David A Koolen , Richard J Rodenburg , Patrick F Chinnery , H J M Smeets , Gráinne S Gorman , Penelope E Bonnen , Robert W Taylor , Michio Hirano

Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential.

Stem cell reports

Avec: Marissa J Stutzman , C S John Kim , David J Tester , Samantha K Hamrick , Steven M Dotzler , John R Giudicessi , Marco C Miotto , Jeevan B Gc , Joachim Frank , Andrew R Marks , Michael J Ackerman

Allosteric modulation of α1β3γ2 GABA

Biophysical journal

Avec: Jeevan B Gc , Christopher T Szlenk , Ayobami Diyaolu , Peter Obi , Haiyang Wei , Xutong Shi , K Michael Gibson , Senthil Natesan , Jean-Baptiste Roullet

Molecular basis for the recognition of 24-(S)-hydroxycholesterol by integrin αvβ3.

Scientific reports

Avec: Jeevan B Gc , Justin Chen , Swechha M Pokharel , Indira Mohanty , Charles Mariasoosai , Peter Obi , Paul Panipinto , Smarajit Bandyopadhyay , Santanu Bose , Senthil Natesan

Integrin activation by the lipid molecule 25-hydroxycholesterol induces a proinflammatory response.

Nature communications

Avec: Swechha M Pokharel , Niraj K Shil , Jeevan B Gc , Zachary T Colburn , Su-Yu Tsai , Jesus A Segovia , Te-Hung Chang , Smarajit Bandyopadhyay , Senthil Natesan , Jonathan C R Jones , Santanu Bose

Réseau de co-auteurs

Senthil Natesan 8 collaborations

Christopher T Szlenk 4 collaborations

Peter Obi 3 collaborations

Justin Chen 2 collaborations

Charles Mariasoosai 2 collaborations

Ayobami Diyaolu 2 collaborations

Joachim Frank 2 collaborations

Swechha M Pokharel 2 collaborations

Smarajit Bandyopadhyay 2 collaborations

Santanu Bose 2 collaborations

Michael J Espiritu 1 collaboration

Jaydeep Yadav 1 collaboration

Michael Larkin 1 collaboration

Robert D Pelletier 1 collaboration

Jeannine M Chan 1 collaboration

John P Harrelson 1 collaboration

Jin Gao 1 collaboration

Xinyue Dong 1 collaboration

Zhenjia Wang 1 collaboration

Jonathan Shintaku 1 collaboration

Wolfgang M Pernice 1 collaboration

Wafaa Eyaid 1 collaboration

Zuben P Brown 1 collaboration

Marti Juanola-Falgarona 1 collaboration

Javier Torres-Torronteras 1 collaboration

Ewen W Sommerville 1 collaboration

Debby Mei Hellebrekers 1 collaboration

Emma L Blakely 1 collaboration

Alan Donaldson 1 collaboration

Ingrid van de Laar 1 collaboration

Cheng-Shiun Leu 1 collaboration

Ramon Marti 1 collaboration

Kurenai Tanji 1 collaboration

David A Koolen 1 collaboration

Richard J Rodenburg 1 collaboration

Patrick F Chinnery 1 collaboration

H J M Smeets 1 collaboration

Gráinne S Gorman 1 collaboration

Penelope E Bonnen 1 collaboration

Robert W Taylor 1 collaboration

Michio Hirano 1 collaboration

Marissa J Stutzman 1 collaboration

C S John Kim 1 collaboration

David J Tester 1 collaboration

Samantha K Hamrick 1 collaboration

Steven M Dotzler 1 collaboration

John R Giudicessi 1 collaboration

Marco C Miotto 1 collaboration

Andrew R Marks 1 collaboration

Michael J Ackerman 1 collaboration

Haiyang Wei 1 collaboration

Xutong Shi 1 collaboration

K Michael Gibson 1 collaboration

Jean-Baptiste Roullet 1 collaboration

Indira Mohanty 1 collaboration

Paul Panipinto 1 collaboration

Niraj K Shil 1 collaboration

Zachary T Colburn 1 collaboration

Su-Yu Tsai 1 collaboration

Jesus A Segovia 1 collaboration

Te-Hung Chang 1 collaboration

Jonathan C R Jones 1 collaboration