Jeremy A Goettel

Affiliations

Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Vanderbilt Institute of Infection, Immunity, and Inflammation, Vanderbilt University Medical Center, Nashville, TN.
Department of Medicine, Division of Gastroenterology, Vanderbilt University School of Medicine, Vanderbilt University Medical Center, Nashville, TN; and.

Publications (23)

IL-17 Receptor Signaling through IL-17A or IL-17F Is Sufficient to Maintain Innate Response and Control of

ImmunoHorizons

Avec: Beverly R E A Dixon , Tiffany J Lee , Diana C Contreras Healey , Jing Li , Jeremy A Goettel , M Blanca Piazuelo , Holly M Scott Algood

Intestinal Inflammation Promotes MDL-1

Cellular and molecular gastroenterology and hepatology

Avec: Christopher T Peek , Caleb A Ford , Kara R Eichelberger , Justin Jacobse , Teresa P Torres , Damian Maseda , Yvonne L Latour , M Blanca Piazuelo , Joshua R Johnson , Mariana X Byndloss , Keith T Wilson , Jeffrey C Rathmell , Jeremy A Goettel , James E Cassat

Humanized mouse models of genetic immune disorders and hematological malignancies.

Biochemical pharmacology

Avec: Rajeev K Tyagi , Jing Li , Justin Jacobse , Scott B Snapper , Dror S Shouval , Jeremy A Goettel

MTG16 regulates colonic epithelial differentiation, colitis, and tumorigenesis by repressing E protein transcription factors.

JCI insight

Avec: Rachel E Brown , Justin Jacobse , Shruti A Anant , Koral M Blunt , Bob Chen , Paige N Vega , Chase T Jones , Jennifer M Pilat , Frank Revetta , Aidan H Gorby , Kristy R Stengel , Yash A Choksi , Kimmo Palin , M Blanca Piazuelo , Mary Kay Washington , Ken S Lau , Jeremy A Goettel , Scott W Hiebert , Sarah P Short , Christopher S Williams

Proton Pump Inhibitors Modulate Gene Expression Profile in Esophageal Mucosa and Microbiome.

The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG

Avec: Seesandra V Rajagopala , Meghan H Shilts , Hernan Correa , Suman R Das , Yash A Choksi , Justin Jacobse , Jeremy A Goettel , Girish Hiremath

Identification of a functional peptide of a probiotic bacterium-derived protein for the sustained effect on preventing colitis.

Gut microbes

Avec: Harpreet Kaur , Syed Azmal Ali , Sarah P Short , Christopher S Williams , Jeremy A Goettel , M Kay Washington , Richard M Peek , Sari A Acra , Fang Yan

HLA-Restriction of Human Treg Cells Is Not Required for Therapeutic Efficacy of Low-Dose IL-2 in Humanized Mice.

Frontiers in immunology

Avec: Rajeev K Tyagi , Justin Jacobse , Jing Li , Margret M Allaman , Kevin L Otipoby , Erik R Sampson , Keith T Wilson , Jeremy A Goettel

Interleukin-23 receptor signaling impairs the stability and function of colonic regulatory T cells.

Cell reports

Avec: Justin Jacobse , Rachel E Brown , Jing Li , Jennifer M Pilat , Ly Pham , Sarah P Short , Christopher T Peek , Andrea Rolong , M Kay Washington , Ruben Martinez-Barricarte , Mariana X Byndloss , Catherine Shelton , Janet G Markle , Yvonne L Latour , Margaret M Allaman , James E Cassat , Keith T Wilson , Yash A Choksi , Christopher S Williams , Ken S Lau , Charles R Flynn , Jean-Laurent Casanova , Edmond H H M Rings , Janneke N Samsom , Jeremy A Goettel

Eosinophils Exert Antitumorigenic Effects in the Development of Esophageal Squamous Cell Carcinoma.

Cellular and molecular gastroenterology and hepatology

Avec: Justin Jacobse , Zaryab Aziz , Lili Sun , Jasmine Chaparro , Jennifer M Pilat , Aaron Kwag , Matthew Buendia , Mae Wimbiscus , Motomi Nasu , Tsuyoshi Saito , Shinji Mine , Hajime Orita , Frank Revetta , Sarah P Short , M Kay Washington , Girish Hiremath , Michael K Gibson , Lori A Coburn , Tatsuki Koyama , Jeremy A Goettel , Christopher S Williams , Yash A Choksi

Intestinal Regulatory T Cells as Specialized Tissue-Restricted Immune Cells in Intestinal Immune Homeostasis and Disease.

Frontiers in immunology

Avec: Justin Jacobse , Jing Li , Edmond H H M Rings , Janneke N Samsom , Jeremy A Goettel

Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps.

Cell

Avec: Bob Chen , Cherie' R Scurrah , Eliot T McKinley , Alan J Simmons , Marisol A Ramirez-Solano , Xiangzhu Zhu , Nicholas O Markham , Cody N Heiser , Paige N Vega , Andrea Rolong , Hyeyon Kim , Quanhu Sheng , Julia L Drewes , Yuan Zhou , Austin N Southard-Smith , Yanwen Xu , James Ro , Angela L Jones , Frank Revetta , Lynne D Berry , Hiroaki Niitsu , Mirazul Islam , Karin Pelka , Matan Hofree , Jonathan H Chen , Siranush Sarkizova , Kimmie Ng , Marios Giannakis , Genevieve M Boland , Andrew J Aguirre , Ana C Anderson , Orit Rozenblatt-Rosen , Aviv Regev , Nir Hacohen , Kenta Kawasaki , Toshiro Sato , Jeremy A Goettel , William M Grady , Wei Zheng , M Kay Washington , Qiuyin Cai , Cynthia L Sears , James R Goldenring , Jeffrey L Franklin , Timothy Su , Won Jae Huh , Simon Vandekar , Joseph T Roland , Qi Liu , Robert J Coffey , Martha J Shrubsole , Ken S Lau

Cystathionine γ-lyase exacerbates Helicobacter pylori immunopathogenesis by promoting macrophage metabolic remodeling and activation.

JCI insight

Avec: Yvonne L Latour , Johanna C Sierra , Jordan L Finley , Mohammad Asim , Daniel P Barry , Margaret M Allaman , Thaddeus M Smith , Kara M McNamara , Paula B Luis , Claus Schneider , Justin Jacobse , Jeremy A Goettel , M Wade Calcutt , Kristie L Rose , Kevin L Schey , Ginger L Milne , Alberto G Delgado , M Blanca Piazuelo , Bindu D Paul , Solomon H Snyder , Alain P Gobert , Keith T Wilson

Eosinophils exert direct and indirect anti-tumorigenic effects in the development of esophageal squamous cell carcinoma.

bioRxiv : the preprint server for biology

Avec: Justin Jacobse , Zaryab Aziz , Lili Sun , Jasmine Chaparro , Jennifer M Pilat , Aaron Kwag , Matthew Buendia , Mae Wimbiscus , Motomi Nasu , Tsuyoshi Saito , Shinji Mine , Hajime Orita , Frank Revetta , Sarah P Short , M Kay Washington , Girish Hiremath , Michael K Gibson , Lori Coburn , Tatsuki Koyama , Jeremy A Goettel , Christopher S Williams , Yash A Choksi

SELENOP modifies sporadic colorectal carcinogenesis and WNT signaling activity through LRP5/6 interactions.

The Journal of clinical investigation

Avec: Jennifer M Pilat , Rachel E Brown , Zhengyi Chen , Nathaniel J Berle , Adrian P Othon , M Kay Washington , Shruti A Anant , Suguru Kurokawa , Victoria H Ng , Joshua J Thompson , Justin Jacobse , Jeremy A Goettel , Ethan Lee , Yash A Choksi , Ken S Lau , Sarah P Short , Christopher S Williams

Distinct roles for interleukin-23 receptor signaling in regulatory T cells in sporadic and inflammation-associated carcinogenesis.

Frontiers in oncology

Avec: Justin Jacobse , Jennifer M Pilat , Jing Li , Rachel E Brown , Aaron Kwag , Matthew A Buendia , Yash A Choksi , M Kay Washington , Christopher S Williams , Nicholas O Markham , Sarah P Short , Jeremy A Goettel

Children with eosinophilic esophagitis non-responsive to combination therapy have distinct esophageal transcriptomic and microbiome profile.

Allergy

Avec: Girish Hiremath , Yash Choksi , Hernan Correa , Justin Jacobse , Suman R Das , Siyuan Ma , Jeremy A Goettel , Seesandra V Rajagopala

Succinate Produced by Intestinal Microbes Promotes Specification of Tuft Cells to Suppress Ileal Inflammation.

Gastroenterology

Avec: Amrita Banerjee , Charles A Herring , Bob Chen , Hyeyon Kim , Alan J Simmons , Austin N Southard-Smith , Margaret M Allaman , James R White , Mary C Macedonia , Eliot T Mckinley , Marisol A Ramirez-Solano , Elizabeth A Scoville , Qi Liu , Keith T Wilson , Robert J Coffey , M Kay Washington , Jeremy A Goettel , Ken S Lau

Utilizing a reductionist model to study host-microbe interactions in intestinal inflammation.

Microbiome

Avec: Amy M Tsou , Jeremy A Goettel , Bin Bao , Amlan Biswas , Yu Hui Kang , Naresh S Redhu , Kaiyue Peng , Gregory G Putzel , Jeffrey Saltzman , Ryan Kelly , Jordan Gringauz , Jared Barends , Mai Hatazaki , Sandra M Frei , Rohini Emani , Ying Huang , Zeli Shen , James G Fox , Jonathan N Glickman , Bruce H Horwitz , Scott B Snapper

Wnt Signaling in the Phenotype and Function of Tumor-Associated Macrophages.

Cancer research

Avec: Megan L Tigue , Matthew A Loberg , Jeremy A Goettel , William A Weiss , Ethan Lee , Vivian L Weiss

Myeloid deletion of talin-1 reduces mucosal macrophages and protects mice from colonic inflammation.

Scientific reports

Avec: Yvonne L Latour , Kara M McNamara , Margaret M Allaman , Daniel P Barry , Thaddeus M Smith , Mohammad Asim , Kamery J Williams , Caroline V Hawkins , Justin Jacobse , Jeremy A Goettel , Alberto G Delgado , M Blanca Piazuelo , M Kay Washington , Alain P Gobert , Keith T Wilson

Wnt/β-catenin signaling is a therapeutic target in anaplastic thyroid carcinoma.

Endocrine

Avec: Diana Diaz , Kensey Bergdorf , Matthew A Loberg , Courtney J Phifer , George J Xu , Quanhu Sheng , Sheau-Chiann Chen , Jamal M Byrant , Megan L Tigue , Heather Hartmann , Sarah L Rohde , James L Netterville , Naira Baregamian , Jeremy A Goettel , Fei Ye , Ethan Lee , Vivian L Weiss

Identification and multimodal characterization of a specialized epithelial cell type associated with Crohn's disease.

Nature communications

Avec: Jia Li , Alan J Simmons , Caroline V Hawkins , Sophie Chiron , Marisol A Ramirez-Solano , Naila Tasneem , Harsimran Kaur , Yanwen Xu , Frank Revetta , Paige N Vega , Shunxing Bao , Can Cui , Regina N Tyree , Larry W Raber , Anna N Conner , Jennifer M Pilat , Justin Jacobse , Kara M McNamara , Margaret M Allaman , Gabriella A Raffa , Alain P Gobert , Mohammad Asim , Jeremy A Goettel , Yash A Choksi , Dawn B Beaulieu , Robin L Dalal , Sara N Horst , Baldeep S Pabla , Yuankai Huo , Bennett A Landman , Joseph T Roland , Elizabeth A Scoville , David A Schwartz , M Kay Washington , Yu Shyr , Keith T Wilson , Lori A Coburn , Ken S Lau , Qi Liu

MTGR1 is required to maintain small intestinal stem cell populations.

Cell death and differentiation

Avec: Sarah P Short , Rachel E Brown , Zhengyi Chen , Jennifer M Pilat , Bailey A McElligott , Leslie M Meenderink , Alexander C Bickart , Koral M Blunt , Justin Jacobse , Jing Wang , Alan J Simmons , Yanwen Xu , Yilin Yang , Bobak Parang , Yash A Choksi , Jeremy A Goettel , Ken S Lau , Scott W Hiebert , Christopher S Williams

Réseau de co-auteurs

Justin Jacobse 16 collaborations

M Kay Washington 10 collaborations

Yash A Choksi 9 collaborations

Jennifer M Pilat 8 collaborations

Sarah P Short 8 collaborations

Christopher S Williams 8 collaborations

Keith T Wilson 7 collaborations

Ken S Lau 7 collaborations

Jing Li 6 collaborations

M Blanca Piazuelo 5 collaborations

Rachel E Brown 5 collaborations

Frank Revetta 5 collaborations

Margaret M Allaman 5 collaborations

Yvonne L Latour 4 collaborations

Girish Hiremath 4 collaborations

Alan J Simmons 4 collaborations

Bob Chen 3 collaborations

Paige N Vega 3 collaborations

Aaron Kwag 3 collaborations

Marisol A Ramirez-Solano 3 collaborations

Yanwen Xu 3 collaborations

Qi Liu 3 collaborations

Mohammad Asim 3 collaborations

Kara M McNamara 3 collaborations

Alain P Gobert 3 collaborations

Ethan Lee 3 collaborations

Christopher T Peek 2 collaborations

Mariana X Byndloss 2 collaborations

James E Cassat 2 collaborations

Rajeev K Tyagi 2 collaborations

Scott B Snapper 2 collaborations

Shruti A Anant 2 collaborations

Koral M Blunt 2 collaborations

Scott W Hiebert 2 collaborations

Seesandra V Rajagopala 2 collaborations

Hernan Correa 2 collaborations

Suman R Das 2 collaborations

Andrea Rolong 2 collaborations

Edmond H H M Rings 2 collaborations

Janneke N Samsom 2 collaborations

Zaryab Aziz 2 collaborations

Lili Sun 2 collaborations

Jasmine Chaparro 2 collaborations

Matthew Buendia 2 collaborations

Mae Wimbiscus 2 collaborations

Motomi Nasu 2 collaborations

Tsuyoshi Saito 2 collaborations

Shinji Mine 2 collaborations

Hajime Orita 2 collaborations

Michael K Gibson 2 collaborations

Lori A Coburn 2 collaborations

Tatsuki Koyama 2 collaborations

Nicholas O Markham 2 collaborations

Hyeyon Kim 2 collaborations

Quanhu Sheng 2 collaborations

Austin N Southard-Smith 2 collaborations

Joseph T Roland 2 collaborations

Robert J Coffey 2 collaborations

Daniel P Barry 2 collaborations

Thaddeus M Smith 2 collaborations

Alberto G Delgado 2 collaborations

Zhengyi Chen 2 collaborations

Elizabeth A Scoville 2 collaborations

Megan L Tigue 2 collaborations

Matthew A Loberg 2 collaborations

Vivian L Weiss 2 collaborations

Caroline V Hawkins 2 collaborations

Beverly R E A Dixon 1 collaboration

Tiffany J Lee 1 collaboration

Diana C Contreras Healey 1 collaboration

Holly M Scott Algood 1 collaboration

Caleb A Ford 1 collaboration

Kara R Eichelberger 1 collaboration

Teresa P Torres 1 collaboration

Damian Maseda 1 collaboration

Joshua R Johnson 1 collaboration

Jeffrey C Rathmell 1 collaboration

Dror S Shouval 1 collaboration

Chase T Jones 1 collaboration

Aidan H Gorby 1 collaboration

Kristy R Stengel 1 collaboration

Kimmo Palin 1 collaboration

Mary Kay Washington 1 collaboration

Meghan H Shilts 1 collaboration

Harpreet Kaur 1 collaboration

Syed Azmal Ali 1 collaboration

Richard M Peek 1 collaboration

Sari A Acra 1 collaboration

Fang Yan 1 collaboration

Margret M Allaman 1 collaboration

Kevin L Otipoby 1 collaboration

Erik R Sampson 1 collaboration

Ly Pham 1 collaboration

Ruben Martinez-Barricarte 1 collaboration

Catherine Shelton 1 collaboration

Janet G Markle 1 collaboration

Charles R Flynn 1 collaboration

Jean-Laurent Casanova 1 collaboration

Cherie' R Scurrah 1 collaboration

Eliot T McKinley 1 collaboration

Xiangzhu Zhu 1 collaboration

Cody N Heiser 1 collaboration

Julia L Drewes 1 collaboration

Yuan Zhou 1 collaboration

James Ro 1 collaboration

Angela L Jones 1 collaboration

Lynne D Berry 1 collaboration

Hiroaki Niitsu 1 collaboration

Mirazul Islam 1 collaboration

Karin Pelka 1 collaboration

Matan Hofree 1 collaboration

Jonathan H Chen 1 collaboration

Siranush Sarkizova 1 collaboration

Kimmie Ng 1 collaboration

Marios Giannakis 1 collaboration

Genevieve M Boland 1 collaboration

Andrew J Aguirre 1 collaboration

Ana C Anderson 1 collaboration

Orit Rozenblatt-Rosen 1 collaboration

Aviv Regev 1 collaboration

Nir Hacohen 1 collaboration

Kenta Kawasaki 1 collaboration

Toshiro Sato 1 collaboration

William M Grady 1 collaboration

Wei Zheng 1 collaboration

Qiuyin Cai 1 collaboration

Cynthia L Sears 1 collaboration

James R Goldenring 1 collaboration

Jeffrey L Franklin 1 collaboration

Timothy Su 1 collaboration

Won Jae Huh 1 collaboration

Simon Vandekar 1 collaboration

Martha J Shrubsole 1 collaboration

Johanna C Sierra 1 collaboration

Jordan L Finley 1 collaboration

Paula B Luis 1 collaboration

Claus Schneider 1 collaboration

M Wade Calcutt 1 collaboration

Kristie L Rose 1 collaboration

Kevin L Schey 1 collaboration

Ginger L Milne 1 collaboration

Bindu D Paul 1 collaboration

Solomon H Snyder 1 collaboration

Lori Coburn 1 collaboration

Nathaniel J Berle 1 collaboration

Adrian P Othon 1 collaboration

Suguru Kurokawa 1 collaboration

Victoria H Ng 1 collaboration

Joshua J Thompson 1 collaboration

Matthew A Buendia 1 collaboration

Yash Choksi 1 collaboration

Siyuan Ma 1 collaboration

Amrita Banerjee 1 collaboration

Charles A Herring 1 collaboration

James R White 1 collaboration

Mary C Macedonia 1 collaboration

Eliot T Mckinley 1 collaboration

Amy M Tsou 1 collaboration

Bin Bao 1 collaboration

Amlan Biswas 1 collaboration

Yu Hui Kang 1 collaboration

Naresh S Redhu 1 collaboration

Kaiyue Peng 1 collaboration

Gregory G Putzel 1 collaboration

Jeffrey Saltzman 1 collaboration

Ryan Kelly 1 collaboration

Jordan Gringauz 1 collaboration

Jared Barends 1 collaboration

Mai Hatazaki 1 collaboration

Sandra M Frei 1 collaboration

Rohini Emani 1 collaboration

Ying Huang 1 collaboration

Zeli Shen 1 collaboration

James G Fox 1 collaboration

Jonathan N Glickman 1 collaboration

Bruce H Horwitz 1 collaboration

William A Weiss 1 collaboration

Kamery J Williams 1 collaboration

Diana Diaz 1 collaboration

Kensey Bergdorf 1 collaboration

Courtney J Phifer 1 collaboration

George J Xu 1 collaboration

Sheau-Chiann Chen 1 collaboration

Jamal M Byrant 1 collaboration

Heather Hartmann 1 collaboration

Sarah L Rohde 1 collaboration

James L Netterville 1 collaboration

Naira Baregamian 1 collaboration

Fei Ye 1 collaboration

Jia Li 1 collaboration

Sophie Chiron 1 collaboration

Naila Tasneem 1 collaboration

Harsimran Kaur 1 collaboration

Shunxing Bao 1 collaboration

Can Cui 1 collaboration

Regina N Tyree 1 collaboration

Larry W Raber 1 collaboration

Anna N Conner 1 collaboration

Gabriella A Raffa 1 collaboration

Dawn B Beaulieu 1 collaboration

Robin L Dalal 1 collaboration

Sara N Horst 1 collaboration

Baldeep S Pabla 1 collaboration

Yuankai Huo 1 collaboration

Bennett A Landman 1 collaboration

David A Schwartz 1 collaboration

Yu Shyr 1 collaboration

Bailey A McElligott 1 collaboration

Leslie M Meenderink 1 collaboration

Alexander C Bickart 1 collaboration

Jing Wang 1 collaboration

Yilin Yang 1 collaboration

Bobak Parang 1 collaboration