John Sarantopoulos

Affiliations

Division of Hematology-Oncology, University of Texas Health Science Center at San Antonio, San Antonio, Texas.

Publications (18)

Phase 1 Open-Label, Multicenter Study of First-in-Class RORγ Agonist LYC-55716 (Cintirorgon): Safety, Tolerability, and Preliminary Evidence of Antitumor Activity.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Devalingam Mahalingam , Judy S Wang , Erika P Hamilton , John Sarantopoulos , John Nemunaitis , Garry Weems , Laura Carter , Xiao Hu , Marshall Schreeder , H Jeffrey Wilkins

Phase I/Ib Clinical Trial of Sabatolimab, an Anti-TIM-3 Antibody, Alone and in Combination with Spartalizumab, an Anti-PD-1 Antibody, in Advanced Solid Tumors.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Giuseppe Curigliano , Hans Gelderblom , Nicolas Mach , Toshihiko Doi , David Tai , Patrick M Forde , John Sarantopoulos , Philippe L Bedard , Chia-Chi Lin , F Stephen Hodi , Sofie Wilgenhof , Armando Santoro , Catherine A Sabatos-Peyton , Tyler A Longmire , Alexandros Xyrafas , Haiying Sun , Sabine Gutzwiller , Luigi Manenti , Aung Naing

A phase 2, multicenter, open-label study of anti-LAG-3 ieramilimab in combination with anti-PD-1 spartalizumab in patients with advanced solid malignancies.

Oncoimmunology

Avec: Chia-Chi Lin , Elena Garralda , Patrick Schöffski , David S Hong , Lillian L Siu , Miguel Martin , Michela Maur , Rina Hui , Ross A Soo , Joanne Chiu , Tian Zhang , Brigette Ma , Chrisann Kyi , Daniel Sw Tan , Philippe A Cassier , John Sarantopoulos , Andrew Weickhardt , Richard D Carvajal , Jennifer Spratlin , Taito Esaki , Fréderic Rolland , Wallace Akerley , Barbara Deschler-Baier , Lawrence Rispoli , Tanay S Samant , Niladri Roy Chowdhury , Daniel Gusenleitner , Eunice L Kwak , Vasileios Askoxylakis , Filippo De Braud

Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours.

British journal of clinical pharmacology

Avec: Devalingam Mahalingam , Manish R Patel , Jasgit C Sachdev , Lowell L Hart , Niels Halama , Ramesh K Ramanathan , John Sarantopoulos , Dirk Völkel , Ashraf Youssef , Floris A de Jong , Apostolia Maria Tsimberidou

Pharmacokinetic Study of Osimertinib in Cancer Patients with Mild or Moderate Hepatic Impairment.

The Journal of pharmacology and experimental therapeutics

Avec: Enrique Grande , R Donald Harvey , Benoit You , Jaime Feliu Batlle , Hal Galbraith , John Sarantopoulos , Suresh S Ramalingam , Helen Mann , Karen So , Martin Johnson , Karthick Vishwanathan

Antitumor Activity of Lurbinectedin, a Selective Inhibitor of Oncogene Transcription, in Patients with Relapsed Ewing Sarcoma: Results of a Basket Phase II Study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Vivek Subbiah , Irene Braña , Alessandra Longhi , Valentina Boni , Jean-Pierre Delord , Ahmad Awada , Pascaline Boudou-Rouquette , John Sarantopoulos , Geoffrey I Shapiro , Anthony Elias , Ravin Ratan , Cristian Fernandez , Carmen Kahatt , Martin Cullell-Young , Mariano Siguero , Ali Zeaiter , Sant P Chawla

A First-in-Human, Phase I, Multicenter, Open-Label, Dose-Escalation Study of PCA062: An Antibody-Drug Conjugate Targeting P-Cadherin, in Patients With Solid Tumors.

Molecular cancer therapeutics

Avec: Matteo Duca , Darren Wan-Teck Lim , Vivek Subbiah , Shunji Takahashi , John Sarantopoulos , Andrea Varga , Joseph A D'Alessio , Tinya Abrams , Qing Sheng , Eugene Youchin Tan , Maria Santos Rosa , Juan Gonzalez-Maffe , Janna Sand-Dejmek , Claire Fabre , Miguel Martin

Phase I/II study of the LAG-3 inhibitor ieramilimab (LAG525) ± anti-PD-1 spartalizumab (PDR001) in patients with advanced malignancies.

Journal for immunotherapy of cancer

Avec: Patrick Schöffski , Daniel S W Tan , Miguel Martín , María Ochoa-de-Olza , John Sarantopoulos , Richard D Carvajal , Chrisann Kyi , Taito Esaki , Amy Prawira , Wallace Akerley , Filippo De Braud , Rina Hui , Tian Zhang , Ross A Soo , Michela Maur , Andrew Weickhardt , Jürgen Krauss , Barbara Deschler-Baier , Allen Lau , Tanay S Samant , Tyler Longmire , Niladri Roy Chowdhury , Catherine A Sabatos-Peyton , Nidhi Patel , Radha Ramesh , Tiancen Hu , Ana Carion , Daniel Gusenleitner , Padmaja Yerramilli-Rao , Vasileios Askoxylakis , Eunice L Kwak , David S Hong

Utilizing metformin to prevent metabolic syndrome due to androgen deprivation therapy (ADT): a randomized phase II study of metformin in non-diabetic men initiating ADT for advanced prostate cancer.

Oncotarget

Avec: Devalingam Mahalingam , Salih Hanni , Anthony V Serritella , Christos Fountzilas , Joel Michalek , Brian Hernandez , John Sarantopoulos , Paromitta Datta , Ofelia Romero , Sureshkumar Mulampurath Achutan Pillai , John Kuhn , Michael Pollak , Ian M Thompson

Lurbinectedin as second-line treatment for patients with small-cell lung cancer: a single-arm, open-label, phase 2 basket trial.

The Lancet. Oncology

Avec: José Trigo , Vivek Subbiah , Benjamin Besse , Victor Moreno , Rafael López , María Angeles Sala , Solange Peters , Santiago Ponce , Cristian Fernández , Vicente Alfaro , Javier Gómez , Carmen Kahatt , Ali Zeaiter , Khalil Zaman , Valentina Boni , Jennifer Arrondeau , Maite Martínez , Jean-Pierre Delord , Ahmad Awada , Rebecca Kristeleit , Maria Eugenia Olmedo , Luciano Wannesson , Javier Valdivia , María Jesús Rubio , Antonio Anton , John Sarantopoulos , Sant P Chawla , Joaquín Mosquera-Martinez , Manolo D'Arcangelo , Armando Santoro , Victor M Villalobos , Jacob Sands , Luis Paz-Ares

Antitumor activity of lurbinectedin in second-line small cell lung cancer patients who are candidates for re-challenge with the first-line treatment.

Lung cancer (Amsterdam, Netherlands)

Avec: Vivek Subbiah , Luis Paz-Ares , Benjamin Besse , Victor Moreno , Solange Peters , María Angeles Sala , José Antonio López-Vilariño , Cristian Fernández , Carmen Kahatt , Vicente Alfaro , Mariano Siguero , Ali Zeaiter , Khalil Zaman , Rafael López , Santiago Ponce , Valentina Boni , Jennifer Arrondeau , Jean-Pierre Delord , Maite Martínez , Luciano Wannesson , Antonio Antón , Javier Valdivia , Ahmad Awada , Rebecca Kristeleit , Maria Eugenia Olmedo , María Jesús Rubio , John Sarantopoulos , Sant P Chawla , Joaquín Mosquera-Martinez , Manolo D' Arcangelo , Armando Santoro , Victor M Villalobos , Jacob Sands , José Trigo

The effect of sonidegib (LDE225) on the pharmacokinetics of bupropion and warfarin in patients with advanced solid tumours.

British journal of clinical pharmacology

Avec: Darcy B Pooler , Dylan B Ness , John Sarantopoulos , Nicholas Squittieri , Shoba Ravichandran , Carolyn D Britten , Ravi K Amaravadi , Ulka Vaishampayan , Patricia LoRusso , Geoffrey I Shapiro , Anthony J Olszanski , Raymond Perez , Martin Gutierrez , Mark Allen O'Rourke , Vincent Chung , James J Lee , Lionel D Lewis

Phase Ib Study of the Histone Deacetylase 6 Inhibitor Citarinostat in Combination With Paclitaxel in Patients With Advanced Solid Tumors.

Frontiers in oncology

Avec: Michael S Gordon , Geoffrey I Shapiro , John Sarantopoulos , Dejan Juric , Brian Lu , Angeliki Zarotiadou , Jamie N Connarn , Yvan Le Bruchec , Calin Dan Dumitru , R Donald Harvey

Modulation of autophagy: a Phase II study of vorinostat plus hydroxychloroquine versus regorafenib in chemotherapy-refractory metastatic colorectal cancer (mCRC).

British journal of cancer

Avec: Sukeshi Patel Arora , Laura Tenner , John Sarantopoulos , Jay Morris , Qianqian Liu , Jenny A Mendez , Tyler Curiel , Joel Michalek , Devalingam Mahalingam

ARRY-382 in Combination with Pembrolizumab in Patients with Advanced Solid Tumors: Results from a Phase 1b/2 Study.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Melissa Johnson , Arkadiusz Z Dudek , Ammar Sukari , Justin Call , Paul R Kunk , Karl Lewis , Justin F Gainor , John Sarantopoulos , Patrice Lee , Adele Golden , Allison Harney , S Michael Rothenberg , Yuanyuan Zhang , Jonathan W Goldman

Pharmacokinetics of the Investigational Aurora A Kinase Inhibitor Alisertib in Adult Patients With Advanced Solid Tumors or Relapsed/Refractory Lymphoma With Varying Degrees of Hepatic Dysfunction.

Journal of clinical pharmacology

Avec: Xiaofei Zhou , A Craig Lockhart , Siqing Fu , John Nemunaitis , John Sarantopoulos , Andreas Muehler , Lakshmi Rangachari , Michael Bargfrede , Karthik Venkatakrishnan

Phase 1 study of M2698, a p70S6K/AKT dual inhibitor, in patients with advanced cancer.

Journal of hematology & oncology

Avec: Apostolia-Maria Tsimberidou , Jamie V Shaw , Dejan Juric , Claire Verschraegen , Amy M Weise , John Sarantopoulos , Gilberto Lopes , John Nemunaitis , Monica Mita , Haeseong Park , Barbara Ellers-Lenz , Hui Tian , Wenyuan Xiong , Remigiusz Kaleta , Razelle Kurzrock

Combined PIK3CA and FGFR Inhibition With Alpelisib and Infigratinib in Patients With PIK3CA-Mutant Solid Tumors, With or Without FGFR Alterations.

JCO precision oncology

Avec: David M Hyman , Ben Tran , Luis Paz-Ares , Jean-Pascal Machiels , Jan H Schellens , Philippe L Bedard , Mario Campone , Philippe A Cassier , John Sarantopoulos , Ulka Vaishampayan , Rashmi Chugh , Amit Mahipal , A Craig Lockhart , Cristiana Sessa , Thomas Zander , Matthew Ng , Giuseppe Curigliano , Jennifer Bendiske , Xueying Chen , Somesh Choudhury , Diana Graus-Porta , Nancy Lewis , Jose Manuel Perez Garcia , María José de Miguel-Luken

Réseau de co-auteurs

Devalingam Mahalingam 4 collaborations

Vivek Subbiah 4 collaborations

John Nemunaitis 3 collaborations

Armando Santoro 3 collaborations

Valentina Boni 3 collaborations

Jean-Pierre Delord 3 collaborations

Ahmad Awada 3 collaborations

Geoffrey I Shapiro 3 collaborations

Carmen Kahatt 3 collaborations

Ali Zeaiter 3 collaborations

Sant P Chawla 3 collaborations

Luis Paz-Ares 3 collaborations

Giuseppe Curigliano 2 collaborations

Philippe L Bedard 2 collaborations

Chia-Chi Lin 2 collaborations

Catherine A Sabatos-Peyton 2 collaborations

Patrick Schöffski 2 collaborations

David S Hong 2 collaborations

Miguel Martin 2 collaborations

Michela Maur 2 collaborations

Rina Hui 2 collaborations

Ross A Soo 2 collaborations

Tian Zhang 2 collaborations

Chrisann Kyi 2 collaborations

Philippe A Cassier 2 collaborations

Andrew Weickhardt 2 collaborations

Richard D Carvajal 2 collaborations

Taito Esaki 2 collaborations

Wallace Akerley 2 collaborations

Barbara Deschler-Baier 2 collaborations

Tanay S Samant 2 collaborations

Niladri Roy Chowdhury 2 collaborations

Daniel Gusenleitner 2 collaborations

Eunice L Kwak 2 collaborations

Vasileios Askoxylakis 2 collaborations

Filippo De Braud 2 collaborations

R Donald Harvey 2 collaborations

Mariano Siguero 2 collaborations

Joel Michalek 2 collaborations

José Trigo 2 collaborations

Benjamin Besse 2 collaborations

Victor Moreno 2 collaborations

Rafael López 2 collaborations

María Angeles Sala 2 collaborations

Solange Peters 2 collaborations

Santiago Ponce 2 collaborations

Cristian Fernández 2 collaborations

Vicente Alfaro 2 collaborations

Khalil Zaman 2 collaborations

Jennifer Arrondeau 2 collaborations

Maite Martínez 2 collaborations

Rebecca Kristeleit 2 collaborations

Maria Eugenia Olmedo 2 collaborations

Luciano Wannesson 2 collaborations

Javier Valdivia 2 collaborations

María Jesús Rubio 2 collaborations

Joaquín Mosquera-Martinez 2 collaborations

Victor M Villalobos 2 collaborations

Jacob Sands 2 collaborations

Ulka Vaishampayan 2 collaborations

Dejan Juric 2 collaborations

A Craig Lockhart 2 collaborations

Judy S Wang 1 collaboration

Erika P Hamilton 1 collaboration

Garry Weems 1 collaboration

Laura Carter 1 collaboration

Xiao Hu 1 collaboration

Marshall Schreeder 1 collaboration

H Jeffrey Wilkins 1 collaboration

Hans Gelderblom 1 collaboration

Nicolas Mach 1 collaboration

Toshihiko Doi 1 collaboration

David Tai 1 collaboration

Patrick M Forde 1 collaboration

F Stephen Hodi 1 collaboration

Sofie Wilgenhof 1 collaboration

Tyler A Longmire 1 collaboration

Alexandros Xyrafas 1 collaboration

Haiying Sun 1 collaboration

Sabine Gutzwiller 1 collaboration

Luigi Manenti 1 collaboration

Aung Naing 1 collaboration

Elena Garralda 1 collaboration

Lillian L Siu 1 collaboration

Joanne Chiu 1 collaboration

Brigette Ma 1 collaboration

Daniel Sw Tan 1 collaboration

Jennifer Spratlin 1 collaboration

Fréderic Rolland 1 collaboration

Lawrence Rispoli 1 collaboration

Manish R Patel 1 collaboration

Jasgit C Sachdev 1 collaboration

Lowell L Hart 1 collaboration

Niels Halama 1 collaboration

Ramesh K Ramanathan 1 collaboration

Dirk Völkel 1 collaboration

Ashraf Youssef 1 collaboration

Floris A de Jong 1 collaboration

Apostolia Maria Tsimberidou 1 collaboration

Enrique Grande 1 collaboration

Benoit You 1 collaboration

Jaime Feliu Batlle 1 collaboration

Hal Galbraith 1 collaboration

Suresh S Ramalingam 1 collaboration

Helen Mann 1 collaboration

Karen So 1 collaboration

Martin Johnson 1 collaboration

Karthick Vishwanathan 1 collaboration

Irene Braña 1 collaboration

Alessandra Longhi 1 collaboration

Pascaline Boudou-Rouquette 1 collaboration

Anthony Elias 1 collaboration

Ravin Ratan 1 collaboration

Cristian Fernandez 1 collaboration

Martin Cullell-Young 1 collaboration

Matteo Duca 1 collaboration

Darren Wan-Teck Lim 1 collaboration

Shunji Takahashi 1 collaboration

Andrea Varga 1 collaboration

Joseph A D'Alessio 1 collaboration

Tinya Abrams 1 collaboration

Qing Sheng 1 collaboration

Eugene Youchin Tan 1 collaboration

Maria Santos Rosa 1 collaboration

Juan Gonzalez-Maffe 1 collaboration

Janna Sand-Dejmek 1 collaboration

Claire Fabre 1 collaboration

Daniel S W Tan 1 collaboration

Miguel Martín 1 collaboration

María Ochoa-de-Olza 1 collaboration

Amy Prawira 1 collaboration

Jürgen Krauss 1 collaboration

Allen Lau 1 collaboration

Tyler Longmire 1 collaboration

Nidhi Patel 1 collaboration

Radha Ramesh 1 collaboration

Tiancen Hu 1 collaboration

Ana Carion 1 collaboration

Padmaja Yerramilli-Rao 1 collaboration

Salih Hanni 1 collaboration

Anthony V Serritella 1 collaboration

Christos Fountzilas 1 collaboration

Brian Hernandez 1 collaboration

Paromitta Datta 1 collaboration

Ofelia Romero 1 collaboration

Sureshkumar Mulampurath Achutan Pillai 1 collaboration

John Kuhn 1 collaboration

Michael Pollak 1 collaboration

Ian M Thompson 1 collaboration

Javier Gómez 1 collaboration

Antonio Anton 1 collaboration

Manolo D'Arcangelo 1 collaboration

José Antonio López-Vilariño 1 collaboration

Antonio Antón 1 collaboration

Manolo D' Arcangelo 1 collaboration

Darcy B Pooler 1 collaboration

Dylan B Ness 1 collaboration

Nicholas Squittieri 1 collaboration

Shoba Ravichandran 1 collaboration

Carolyn D Britten 1 collaboration

Ravi K Amaravadi 1 collaboration

Patricia LoRusso 1 collaboration

Anthony J Olszanski 1 collaboration

Raymond Perez 1 collaboration

Martin Gutierrez 1 collaboration

Mark Allen O'Rourke 1 collaboration

Vincent Chung 1 collaboration

James J Lee 1 collaboration

Lionel D Lewis 1 collaboration

Michael S Gordon 1 collaboration

Brian Lu 1 collaboration

Angeliki Zarotiadou 1 collaboration

Jamie N Connarn 1 collaboration

Yvan Le Bruchec 1 collaboration

Calin Dan Dumitru 1 collaboration

Sukeshi Patel Arora 1 collaboration

Laura Tenner 1 collaboration

Jay Morris 1 collaboration

Qianqian Liu 1 collaboration

Jenny A Mendez 1 collaboration

Tyler Curiel 1 collaboration

Melissa Johnson 1 collaboration

Arkadiusz Z Dudek 1 collaboration

Ammar Sukari 1 collaboration

Justin Call 1 collaboration

Paul R Kunk 1 collaboration

Karl Lewis 1 collaboration

Justin F Gainor 1 collaboration

Patrice Lee 1 collaboration

Adele Golden 1 collaboration

Allison Harney 1 collaboration

S Michael Rothenberg 1 collaboration

Yuanyuan Zhang 1 collaboration

Jonathan W Goldman 1 collaboration

Xiaofei Zhou 1 collaboration

Siqing Fu 1 collaboration

Andreas Muehler 1 collaboration

Lakshmi Rangachari 1 collaboration

Michael Bargfrede 1 collaboration

Karthik Venkatakrishnan 1 collaboration

Apostolia-Maria Tsimberidou 1 collaboration

Jamie V Shaw 1 collaboration

Claire Verschraegen 1 collaboration

Amy M Weise 1 collaboration

Gilberto Lopes 1 collaboration

Monica Mita 1 collaboration

Haeseong Park 1 collaboration

Barbara Ellers-Lenz 1 collaboration

Hui Tian 1 collaboration

Wenyuan Xiong 1 collaboration

Remigiusz Kaleta 1 collaboration

Razelle Kurzrock 1 collaboration

David M Hyman 1 collaboration

Ben Tran 1 collaboration

Jean-Pascal Machiels 1 collaboration

Jan H Schellens 1 collaboration

Mario Campone 1 collaboration

Rashmi Chugh 1 collaboration

Amit Mahipal 1 collaboration

Cristiana Sessa 1 collaboration

Thomas Zander 1 collaboration

Matthew Ng 1 collaboration

Jennifer Bendiske 1 collaboration

Xueying Chen 1 collaboration

Somesh Choudhury 1 collaboration

Diana Graus-Porta 1 collaboration

Nancy Lewis 1 collaboration

Jose Manuel Perez Garcia 1 collaboration

María José de Miguel-Luken 1 collaboration