Julia M Shifman

ORCID: 0000-0001-6678-6497

Publications (12)

ProBASS - a language model with sequence and structural features for predicting the effect of mutations on binding affinity.

bioRxiv : the preprint server for biology

Avec: Sagara N S Gurusinghe , Yibing Wu , William DeGrado , Julia M Shifman

Engineered TIMP2 with narrow MMP-9 specificity is an effective inhibitor of invasion and proliferation of triple negative breast cancer cells.

The Journal of biological chemistry

Avec: Naama Rotenberg , Mark Feldman , Jason Shirian , Alexandra Hockla , Evette S Radisky , Julia M Shifman

Proximal Co-Translation Facilitates Detection of Weak Protein-Protein Interactions.

International journal of molecular sciences

Avec: Alina Kordonsky , Matan Gabay , Aurelia Rosinoff , Reut Avishid , Amir Flornetin , Noam Deouell , Taimaa Abd Alkhaleq , Noa Efron , Shoham Milshtein , Julia M Shifman , Maayan Gal , Gali Prag

Allosteric Modulation of Binding Specificity by Alternative Packing of Protein Cores.

Journal of molecular biology

Avec: Moshe Ben-David , Haiming Huang , Mark G F Sun , Carles Corbi-Verge , Evangelia Petsalaki , Ke Liu , David Gfeller , Pankaj Garg , Wolfram Tempel , Irina Sochirca , Julia M Shifman , Alan Davidson , Jinrong Min , Philip M Kim , Sachdev S Sidhu

Cold Spot SCANNER: Colab Notebook for predicting cold spots in protein-protein interfaces.

BMC bioinformatics

Avec: Sagara N S Gurusinghe , Julia M Shifman

Targeting Ras with protein engineering.

Oncotarget

Avec: Atilio Tomazini , Julia M Shifman

Mirror-Image Random Nonstandard Peptide Integrated Discovery (MI-RaPID) Technology Yields Highly Stable and Selective Macrocyclic Peptide Inhibitors for Matrix Metallopeptidase 7.

Angewandte Chemie (International ed. in English)

Avec: Norman Metanis , Hiba Ghareeb , Choi Yi Li , Anjana Shenoy , Naama Rotenberg , Julia M Shifman , Takayuki Katoh , Irit Sagi , Hiroaki Suga

RASSF effectors couple diverse RAS subfamily GTPases to the Hippo pathway.

Science signaling

Avec: Thillaivillalan Dhanaraman , Swati Singh , Ryan C Killoran , Anamika Singh , Xingjian Xu , Julia M Shifman , Matthew J Smith

Climbing Up and Down Binding Landscapes through Deep Mutational Scanning of Three Homologous Protein-Protein Complexes.

Journal of the American Chemical Society

Avec: Michael Heyne , Jason Shirian , Itay Cohen , Yoav Peleg , Evette S Radisky , Niv Papo , Julia M Shifman

Generating quantitative binding landscapes through fractional binding selections combined with deep sequencing and data normalization.

Nature communications

Avec: Michael Heyne , Niv Papo , Julia M Shifman

Engineered variants of the Ras effector protein RASSF5 (NORE1A) promote anticancer activities in lung adenocarcinoma.

The Journal of biological chemistry

Avec: Anamika Singh , Ariel Erijman , Ashish Noronha , Hemant Kumar , Yoav Peleg , Yosef Yarden , Julia M Shifman

Computational design and experimental optimization of protein binders with prospects for biomedical applications.

Protein engineering, design & selection : PEDS

Avec: Alessandro Bonadio , Julia M Shifman

Réseau de co-auteurs

Sagara N S Gurusinghe 2 collaborations

Naama Rotenberg 2 collaborations

Jason Shirian 2 collaborations

Evette S Radisky 2 collaborations

Anamika Singh 2 collaborations

Michael Heyne 2 collaborations

Yoav Peleg 2 collaborations

Niv Papo 2 collaborations

Yibing Wu 1 collaboration

William DeGrado 1 collaboration

Mark Feldman 1 collaboration

Alexandra Hockla 1 collaboration

Alina Kordonsky 1 collaboration

Matan Gabay 1 collaboration

Aurelia Rosinoff 1 collaboration

Reut Avishid 1 collaboration

Amir Flornetin 1 collaboration

Noam Deouell 1 collaboration

Taimaa Abd Alkhaleq 1 collaboration

Noa Efron 1 collaboration

Shoham Milshtein 1 collaboration

Maayan Gal 1 collaboration

Gali Prag 1 collaboration

Moshe Ben-David 1 collaboration

Haiming Huang 1 collaboration

Mark G F Sun 1 collaboration

Carles Corbi-Verge 1 collaboration

Evangelia Petsalaki 1 collaboration

Ke Liu 1 collaboration

David Gfeller 1 collaboration

Pankaj Garg 1 collaboration

Wolfram Tempel 1 collaboration

Irina Sochirca 1 collaboration

Alan Davidson 1 collaboration

Jinrong Min 1 collaboration

Philip M Kim 1 collaboration

Sachdev S Sidhu 1 collaboration

Atilio Tomazini 1 collaboration

Norman Metanis 1 collaboration

Hiba Ghareeb 1 collaboration

Choi Yi Li 1 collaboration

Anjana Shenoy 1 collaboration

Takayuki Katoh 1 collaboration

Irit Sagi 1 collaboration

Hiroaki Suga 1 collaboration

Thillaivillalan Dhanaraman 1 collaboration

Swati Singh 1 collaboration

Ryan C Killoran 1 collaboration

Xingjian Xu 1 collaboration

Matthew J Smith 1 collaboration

Itay Cohen 1 collaboration

Ariel Erijman 1 collaboration

Ashish Noronha 1 collaboration

Hemant Kumar 1 collaboration

Yosef Yarden 1 collaboration

Alessandro Bonadio 1 collaboration