Jyothi Parvathareddy

Affiliations

Regional Biocontainment Laboratory, University of Tennessee Health Science Center, Memphis, Tennessee, USA.

Publications (14)

Emergence and Magnitude of ML336 Resistance in Venezuelan Equine Encephalitis Virus Depend on the Microenvironment.

Journal of virology

Avec: Jasper Lee , Jyothi Parvathareddy , Dong Yang , Shruti Bansal , Kathryn O'Connell , Jennifer E Golden , Colleen B Jonsson

Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2.

Research square

Avec: Brian Sanders , Suman Pokhrel , Audrey Labbe , Irimpan Mathews , Connor Cooper , Russell Davidson , Gwyndalyn Phillips , Kevin Weiss , Qiu Zhang , Hugh O'Neill , Manat Kaur , Lori Ferrins , Jurgen Schmidt , Walter Reichard , Surekha Surendranathan , Jyothi Parvathareddy , Lexi Phillips , Christopher Rainville , David Sterner , Desigan Kumaran , Babak Andi , Gyorgy Babnigg , Nigel Moriarrty , Paul Adams , Andrzej Joachimiak , Brett Hurst , Suresh Kumar , Tauseef Butt , Colleen Jonsson , Soichi Wakatsuki , Stephanie Galanie , Martha Head , Jerry Parks

Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease.

Nature communications

Avec: Daniel W Kneller , Hui Li , Gwyndalyn Phillips , Kevin L Weiss , Qiu Zhang , Mark A Arnould , Colleen B Jonsson , Surekha Surendranathan , Jyothi Parvathareddy , Matthew P Blakeley , Leighton Coates , John M Louis , Peter V Bonnesen , Andrey Kovalevsky

Efficacy of a brain-penetrant antiviral in lethal Venezuelan and eastern equine encephalitis mouse models.

Science translational medicine

Avec: Xufeng Cao , Dong Yang , Jyothi Parvathareddy , Yong-Kyu Chu , Eun Jung Kim , Jhewelle N Fitz-Henley , Xiaoyu Li , Pradeep B Lukka , Keyur R Parmar , Zaid H Temrikar , Priya Dhole , Robert Scott Adcock , Jon Gabbard , Shruti Bansal , Jasper Lee , Lillian Zalduondo , Ernestine Hayes , Jennifer Stabenow , Bernd Meibohm , Elizabeth A Fitzpatrick , Kevin Bailey , Rafael K Campos , Justin G Julander , Shannan L Rossi , Donghoon Chung , Colleen B Jonsson , Jennifer E Golden

Dissecting Phenotype from Genotype with Clinical Isolates of SARS-CoV-2 First Wave Variants.

Viruses

Avec: Mariah K Taylor , Evan P Williams , Yi Xue , Piroon Jenjaroenpun , Thidathip Wongsurawat , Amanda P Smith , Amber M Smith , Jyothi Parvathareddy , Ying Kong , Peter Vogel , Xueyuan Cao , Walter Reichard , Briana Spruill-Harrell , Amali E Samarasinghe , Intawat Nookaew , Elizabeth A Fitzpatrick , Micholas Dean Smith , Michelle Aranha , Jeremy C Smith , Colleen B Jonsson

Virtual and

ACS pharmacology & translational science

Avec: Giovanni Bocci , Steven B Bradfute , Chunyan Ye , Matthew J Garcia , Jyothi Parvathareddy , Walter Reichard , Surekha Surendranathan , Shruti Bansal , Cristian G Bologa , Douglas J Perkins , Colleen B Jonsson , Larry A Sklar , Tudor I Oprea

Covalent narlaprevir- and boceprevir-derived hybrid inhibitors of SARS-CoV-2 main protease: room-temperature X-ray and neutron crystallography, binding thermodynamics, and antiviral activity.

Research square

Avec: Daniel Kneller , Hui Li , Gwyndalyn Phillips , Kevin Weiss , Qiu Zhang , Mark Arnould , Colleen Jonsson , Surekha Surendranathan , Jyothi Parvathareddy , Matthew Blakeley , Leighton Coates , John Louis , Peter Bonnesen , Andrey Kovalevsky

Drug Repurposing to Identify Nilotinib as a Potential SARS-CoV-2 Main Protease Inhibitor: Insights from a Computational and

Journal of chemical information and modeling

Avec: Souvik Banerjee , Shalini Yadav , Sourav Banerjee , Sayo O Fakayode , Jyothi Parvathareddy , Walter Reichard , Surekha Surendranathan , Foyez Mahmud , Ryan Whatcott , Joshua Thammathong , Bernd Meibohm , Duane D Miller , Colleen B Jonsson , Kshatresh Dutta Dubey

Cardiopulmonary Injury in the Syrian Hamster Model of COVID-19.

Viruses

Avec: Yi Xue , Dong Yang , Peter Vogel , Jennifer Stabenow , Lillian Zalduondo , Ying Kong , Yazhini Ravi , Chittoor B Sai-Sudhakar , Jyothi Parvathareddy , Ernestine Hayes , Shannon Taylor , Elizabeth Fitzpatrick , Colleen B Jonsson

Potent and Selective Covalent Inhibition of the Papain-like Protease from SARS-CoV-2.

Research square

Avec: Brian Sanders , Suman Pokhrel , Audrey Labbe , Irimpan Mathews , Connor Cooper , Russell Davidson , Gwyndalyn Phillips , Kevin Weiss , Qiu Zhang , Hugh O'Neill , Manat Kaur , Lori Ferrins , Jurgen Schmidt , Walter Reichard , Surekha Surendranathan , Jyothi Parvathareddy , Lexi Phillips , Christopher Rainville , David Sterner , Desigan Kumaran , Babak Andi , Gyorgy Babnigg , Nigel Moriarty , Paul Adams , Andrzej Joachimiak , Brett Hurst , Suresh Kumar , Tauseef Butt , Colleen Jonsson , Soichi Wakatsuki , Stephanie Galanie , Martha Head , Jerry Parks

AI-Accelerated Design of Targeted Covalent Inhibitors for SARS-CoV-2.

Journal of chemical information and modeling

Avec: Rajendra P Joshi , Katherine J Schultz , Jesse William Wilson , Agustin Kruel , Rohith Anand Varikoti , Chathuri J Kombala , Daniel W Kneller , Stephanie Galanie , Gwyndalyn Phillips , Qiu Zhang , Leighton Coates , Jyothi Parvathareddy , Surekha Surendranathan , Ying Kong , Austin Clyde , Arvind Ramanathan , Colleen B Jonsson , Kristoffer R Brandvold , Mowei Zhou , Martha S Head , Andrey Kovalevsky , Neeraj Kumar

Rapid Sequencing of Multiple RNA Viruses in Their Native Form.

Frontiers in microbiology

Avec: Thidathip Wongsurawat , Piroon Jenjaroenpun , Mariah K Taylor , Jasper Lee , Aline Lavado Tolardo , Jyothi Parvathareddy , Sangam Kandel , Taylor D Wadley , Bualan Kaewnapan , Niracha Athipanyasilp , Andrew Skidmore , Donghoon Chung , Chutikarn Chaimayo , Michael Whitt , Wannee Kantakamalakul , Ruengpung Sutthent , Navin Horthongkham , David W Ussery , Colleen B Jonsson , Intawat Nookaew

Upper Respiratory Infection Drives Clinical Signs and Inflammatory Responses Following Heterologous Challenge of SARS-CoV-2 Variants of Concern in K18 Mice.

Viruses

Avec: Jacob H Nichols , Evan P Williams , Jyothi Parvathareddy , Xueyuan Cao , Ying Kong , Elizabeth Fitzpatrick , Richard J Webby , Colleen B Jonsson

Potent and selective covalent inhibition of the papain-like protease from SARS-CoV-2.

Nature communications

Avec: Brian C Sanders , Suman Pokhrel , Audrey D Labbe , Irimpan I Mathews , Connor J Cooper , Russell B Davidson , Gwyndalyn Phillips , Kevin L Weiss , Qiu Zhang , Hugh O'Neill , Manat Kaur , Jurgen G Schmidt , Walter Reichard , Surekha Surendranathan , Jyothi Parvathareddy , Lexi Phillips , Christopher Rainville , David E Sterner , Desigan Kumaran , Babak Andi , Gyorgy Babnigg , Nigel W Moriarty , Paul D Adams , Andrzej Joachimiak , Brett L Hurst , Suresh Kumar , Tauseef R Butt , Colleen B Jonsson , Lori Ferrins , Soichi Wakatsuki , Stephanie Galanie , Martha S Head , Jerry M Parks

Réseau de co-auteurs

Colleen B Jonsson 11 collaborations

Surekha Surendranathan 8 collaborations

Gwyndalyn Phillips 6 collaborations

Qiu Zhang 6 collaborations

Walter Reichard 6 collaborations

Stephanie Galanie 4 collaborations

Ying Kong 4 collaborations

Jasper Lee 3 collaborations

Dong Yang 3 collaborations

Shruti Bansal 3 collaborations

Suman Pokhrel 3 collaborations

Kevin Weiss 3 collaborations

Hugh O'Neill 3 collaborations

Manat Kaur 3 collaborations

Lori Ferrins 3 collaborations

Lexi Phillips 3 collaborations

Christopher Rainville 3 collaborations

Desigan Kumaran 3 collaborations

Babak Andi 3 collaborations

Gyorgy Babnigg 3 collaborations

Andrzej Joachimiak 3 collaborations

Suresh Kumar 3 collaborations

Colleen Jonsson 3 collaborations

Soichi Wakatsuki 3 collaborations

Leighton Coates 3 collaborations

Andrey Kovalevsky 3 collaborations

Jennifer E Golden 2 collaborations

Brian Sanders 2 collaborations

Audrey Labbe 2 collaborations

Irimpan Mathews 2 collaborations

Connor Cooper 2 collaborations

Russell Davidson 2 collaborations

Jurgen Schmidt 2 collaborations

David Sterner 2 collaborations

Paul Adams 2 collaborations

Brett Hurst 2 collaborations

Tauseef Butt 2 collaborations

Martha Head 2 collaborations

Jerry Parks 2 collaborations

Daniel W Kneller 2 collaborations

Hui Li 2 collaborations

Kevin L Weiss 2 collaborations

Lillian Zalduondo 2 collaborations

Ernestine Hayes 2 collaborations

Jennifer Stabenow 2 collaborations

Bernd Meibohm 2 collaborations

Elizabeth A Fitzpatrick 2 collaborations

Donghoon Chung 2 collaborations

Mariah K Taylor 2 collaborations

Evan P Williams 2 collaborations

Yi Xue 2 collaborations

Piroon Jenjaroenpun 2 collaborations

Thidathip Wongsurawat 2 collaborations

Peter Vogel 2 collaborations

Xueyuan Cao 2 collaborations

Intawat Nookaew 2 collaborations

Elizabeth Fitzpatrick 2 collaborations

Martha S Head 2 collaborations

Kathryn O'Connell 1 collaboration

Nigel Moriarrty 1 collaboration

Mark A Arnould 1 collaboration

Matthew P Blakeley 1 collaboration

John M Louis 1 collaboration

Peter V Bonnesen 1 collaboration

Xufeng Cao 1 collaboration

Yong-Kyu Chu 1 collaboration

Eun Jung Kim 1 collaboration

Jhewelle N Fitz-Henley 1 collaboration

Xiaoyu Li 1 collaboration

Pradeep B Lukka 1 collaboration

Keyur R Parmar 1 collaboration

Zaid H Temrikar 1 collaboration

Priya Dhole 1 collaboration

Robert Scott Adcock 1 collaboration

Jon Gabbard 1 collaboration

Kevin Bailey 1 collaboration

Rafael K Campos 1 collaboration

Justin G Julander 1 collaboration

Shannan L Rossi 1 collaboration

Amanda P Smith 1 collaboration

Amber M Smith 1 collaboration

Briana Spruill-Harrell 1 collaboration

Amali E Samarasinghe 1 collaboration

Micholas Dean Smith 1 collaboration

Michelle Aranha 1 collaboration

Jeremy C Smith 1 collaboration

Giovanni Bocci 1 collaboration

Steven B Bradfute 1 collaboration

Chunyan Ye 1 collaboration

Matthew J Garcia 1 collaboration

Cristian G Bologa 1 collaboration

Douglas J Perkins 1 collaboration

Larry A Sklar 1 collaboration

Tudor I Oprea 1 collaboration

Daniel Kneller 1 collaboration

Mark Arnould 1 collaboration

Matthew Blakeley 1 collaboration

John Louis 1 collaboration

Peter Bonnesen 1 collaboration

Souvik Banerjee 1 collaboration

Shalini Yadav 1 collaboration

Sourav Banerjee 1 collaboration

Sayo O Fakayode 1 collaboration

Foyez Mahmud 1 collaboration

Ryan Whatcott 1 collaboration

Joshua Thammathong 1 collaboration

Duane D Miller 1 collaboration

Kshatresh Dutta Dubey 1 collaboration

Yazhini Ravi 1 collaboration

Chittoor B Sai-Sudhakar 1 collaboration

Shannon Taylor 1 collaboration

Nigel Moriarty 1 collaboration

Rajendra P Joshi 1 collaboration

Katherine J Schultz 1 collaboration

Jesse William Wilson 1 collaboration

Agustin Kruel 1 collaboration

Rohith Anand Varikoti 1 collaboration

Chathuri J Kombala 1 collaboration

Austin Clyde 1 collaboration

Arvind Ramanathan 1 collaboration

Kristoffer R Brandvold 1 collaboration

Mowei Zhou 1 collaboration

Neeraj Kumar 1 collaboration

Aline Lavado Tolardo 1 collaboration

Sangam Kandel 1 collaboration

Taylor D Wadley 1 collaboration

Bualan Kaewnapan 1 collaboration

Niracha Athipanyasilp 1 collaboration

Andrew Skidmore 1 collaboration

Chutikarn Chaimayo 1 collaboration

Michael Whitt 1 collaboration

Wannee Kantakamalakul 1 collaboration

Ruengpung Sutthent 1 collaboration

Navin Horthongkham 1 collaboration

David W Ussery 1 collaboration

Jacob H Nichols 1 collaboration

Richard J Webby 1 collaboration

Brian C Sanders 1 collaboration

Audrey D Labbe 1 collaboration

Irimpan I Mathews 1 collaboration

Connor J Cooper 1 collaboration

Russell B Davidson 1 collaboration

Jurgen G Schmidt 1 collaboration

David E Sterner 1 collaboration

Nigel W Moriarty 1 collaboration

Paul D Adams 1 collaboration

Brett L Hurst 1 collaboration

Tauseef R Butt 1 collaboration

Jerry M Parks 1 collaboration