K Smith-Jackson

Affiliations

Complement Therapeutics Research Group, Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, NE2 4HH, UK.
National Renal Complement Therapeutics Centre, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, UK.

Publications (10)

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice.

The Journal of clinical investigation

Avec: Kate Smith-Jackson , Yi Yang , Harriet Denton , Isabel Y Pappworth , Katie Cooke , Paul N Barlow , John P Atkinson , M Kathryn Liszewski , Matthew C Pickering , David Kavanagh , H Terence Cook , Kevin J Marchbank

Assessing the Impact of Prophylactic Eculizumab on Renal Graft Survival in Atypical Hemolytic Uremic Syndrome.

Transplantation

Avec: Emily K Glover , Kate Smith-Jackson , Vicky Brocklebank , Valerie Wilson , Patrick R Walsh , Emma K Montgomery , Edwin K S Wong , Sally Johnson , Michal Malina , David Kavanagh , Neil S Sheerin , Auteur inconnu

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD.

Frontiers in immunology

Avec: Edwin K S Wong , Thomas M Hallam , Vicky Brocklebank , Patrick R Walsh , Kate Smith-Jackson , Victoria G Shuttleworth , Thomas E Cox , Holly E Anderson , Paul Nigel Barlow , Kevin James Marchbank , Claire L Harris , David Kavanagh

Atypical hemolytic uremic syndrome in the era of terminal complement inhibition: an observational cohort study.

Blood

Avec: Vicky Brocklebank , Patrick R Walsh , Kate Smith-Jackson , Thomas M Hallam , Kevin J Marchbank , Valerie Wilson , Theophile Bigirumurame , Tina Dutt , Emma K Montgomery , Michal Malina , Edwin K S Wong , Sally Johnson , Neil S Sheerin , David Kavanagh

Homodimeric Minimal Factor H:

Frontiers in immunology

Avec: Ola Kamala , Talat H Malik , Thomas M Hallam , Thomas E Cox , Yi Yang , Falguni Vyas , Saimir Luli , Chloe Connelly , Beth Gibson , Kate Smith-Jackson , Harriet Denton , Isabel Y Pappworth , Lei Huang , David Kavanagh , Matthew C Pickering , Kevin J Marchbank

A novel method for real-time analysis of the complement C3b:FH:FI complex reveals dominant negative

Frontiers in immunology

Avec: Thomas M Hallam , Thomas E Cox , Kate Smith-Jackson , Vicky Brocklebank , April J Baral , Nikolaos Tzoumas , David H Steel , Edwin K S Wong , Victoria G Shuttleworth , Andrew J Lotery , Claire L Harris , Kevin J Marchbank , David Kavanagh

Long-term outcomes and response to treatment in diacylglycerol kinase epsilon nephropathy.

Kidney international

Avec: Vicky Brocklebank , Gurinder Kumar , Alexander J Howie , Jayanthi Chandar , David V Milford , Janet Craze , Jonathan Evans , Eric Finlay , Michael Freundlich , Daniel P Gale , Carol Inward , Martin Mraz , Caroline Jones , William Wong , Stephen D Marks , John Connolly , Bronte M Corner , Kate Smith-Jackson , Patrick R Walsh , Kevin J Marchbank , Claire L Harris , Valerie Wilson , Edwin K S Wong , Michal Malina , Sally Johnson , Neil S Sheerin , David Kavanagh

The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade.

Human molecular genetics

Avec: O McMahon , T M Hallam , S Patel , C L Harris , A Menny , W M Zelek , R Widjajahakim , A Java , T E Cox , N Tzoumas , D H W Steel , V G Shuttleworth , K Smith-Jackson , V Brocklebank , H Griffiths , A J Cree , J P Atkinson , A J Lotery , D Bubeck , B P Morgan , K J Marchbank , J M Seddon , D Kavanagh

Plasminogen activator-coated nanobubbles targeting cellbound β2-glycoprotein I as a novel thrombus-specific thrombolytic strategy.

Haematologica

Avec: Paolo Macor , Paolo Durigutto , Monica Argenziano , Kate Smith-Jackson , Sara Capolla , Valeria Di Leonardo , Kevin Marchbank , Valerio Stefano Tolva , Fabrizio Semeraro , Concetta T Ammollo , Mario Colucci , Roberta Cavalli , Pierluigi Meroni , Francesco Tedesco

Alternative pathway activation in pregnancy, a measured amount "complements" a successful pregnancy, too much results in adverse events.

Immunological reviews

Avec: Kate Smith-Jackson , Richard Alexander Harrison

Réseau de co-auteurs

Kate Smith-Jackson 9 collaborations

David Kavanagh 7 collaborations

Kevin J Marchbank 5 collaborations

Vicky Brocklebank 5 collaborations

Edwin K S Wong 5 collaborations

Patrick R Walsh 4 collaborations

Thomas M Hallam 4 collaborations

Valerie Wilson 3 collaborations

Sally Johnson 3 collaborations

Michal Malina 3 collaborations

Neil S Sheerin 3 collaborations

Thomas E Cox 3 collaborations

Claire L Harris 3 collaborations

Yi Yang 2 collaborations

Harriet Denton 2 collaborations

Isabel Y Pappworth 2 collaborations

Matthew C Pickering 2 collaborations

Emma K Montgomery 2 collaborations

Victoria G Shuttleworth 2 collaborations

Katie Cooke 1 collaboration

Paul N Barlow 1 collaboration

John P Atkinson 1 collaboration

M Kathryn Liszewski 1 collaboration

H Terence Cook 1 collaboration

Emily K Glover 1 collaboration

None None 1 collaboration

Holly E Anderson 1 collaboration

Paul Nigel Barlow 1 collaboration

Kevin James Marchbank 1 collaboration

Theophile Bigirumurame 1 collaboration

Tina Dutt 1 collaboration

Ola Kamala 1 collaboration

Talat H Malik 1 collaboration

Falguni Vyas 1 collaboration

Saimir Luli 1 collaboration

Chloe Connelly 1 collaboration

Beth Gibson 1 collaboration

Lei Huang 1 collaboration

April J Baral 1 collaboration

Nikolaos Tzoumas 1 collaboration

David H Steel 1 collaboration

Andrew J Lotery 1 collaboration

Gurinder Kumar 1 collaboration

Alexander J Howie 1 collaboration

Jayanthi Chandar 1 collaboration

David V Milford 1 collaboration

Janet Craze 1 collaboration

Jonathan Evans 1 collaboration

Eric Finlay 1 collaboration

Michael Freundlich 1 collaboration

Daniel P Gale 1 collaboration

Carol Inward 1 collaboration

Martin Mraz 1 collaboration

Caroline Jones 1 collaboration

William Wong 1 collaboration

Stephen D Marks 1 collaboration

John Connolly 1 collaboration

Bronte M Corner 1 collaboration

O McMahon 1 collaboration

T M Hallam 1 collaboration

S Patel 1 collaboration

C L Harris 1 collaboration

A Menny 1 collaboration

W M Zelek 1 collaboration

R Widjajahakim 1 collaboration

A Java 1 collaboration

T E Cox 1 collaboration

N Tzoumas 1 collaboration

D H W Steel 1 collaboration

V G Shuttleworth 1 collaboration

V Brocklebank 1 collaboration

H Griffiths 1 collaboration

A J Cree 1 collaboration

J P Atkinson 1 collaboration

A J Lotery 1 collaboration

D Bubeck 1 collaboration

B P Morgan 1 collaboration

K J Marchbank 1 collaboration

J M Seddon 1 collaboration

D Kavanagh 1 collaboration

Paolo Macor 1 collaboration

Paolo Durigutto 1 collaboration

Monica Argenziano 1 collaboration

Sara Capolla 1 collaboration

Valeria Di Leonardo 1 collaboration

Kevin Marchbank 1 collaboration

Valerio Stefano Tolva 1 collaboration

Fabrizio Semeraro 1 collaboration

Concetta T Ammollo 1 collaboration

Mario Colucci 1 collaboration

Roberta Cavalli 1 collaboration

Pierluigi Meroni 1 collaboration

Francesco Tedesco 1 collaboration

Richard Alexander Harrison 1 collaboration