Karen Augustine-Rauch

Affiliations

Bristol Myers Squibb, Research and Early Development, P.O. Box 4000, Princeton, New Jersey 08544, United States.

Publications (6)

Long-Acting Tumor-Activated Prodrug of a TGFβR Inhibitor.

Journal of medicinal chemistry

Avec: Yong Zhang , Karen E Parrish , David R Tortolani , Michael A Poss , Audris Huang , Honghe Wan , Ashok V Purandare , Andrew F Donnell , James Kempson , Xiaoping Hou , Joseph Pawluczyk , Shiuhang Yip , Emily Luk , Nimmi Raghavan , Jesse Swanson , James Smalley , Anwar Murtaza , Zheng Yang , Karen Augustine-Rauch , Louis J Lombardo , Robert Borzilleri

Concordance of 3 alternative teratogenicity assays with results from corresponding in vivo embryo-fetal development studies: Final report from the International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) DruSafe working group 2.

Regulatory toxicology and pharmacology : RTP

Avec: M McNerney , D Potter , K Augustine-Rauch , P Barrow , B Beyer , K Brannen , S Engel , B P Enright , W S Nowland , N Powles-Glover , S Powlin , M J Schneidkraut , D Stanislaus , K Turner , M Graziano

TGFβ2 and TGFβ3 mediate appropriate context-dependent phenotype of rat valvular interstitial cells.

iScience

Avec: Faye Wang , Cindy Zhang , Jae Kwagh , Brian Strassle , Jinqing Li , Minxue Huang , Yunling Song , Brenda Lehman , Richard Westhouse , Kamalavenkatesh Palanisamy , Vinay K Holenarsipur , Robert Borzilleri , Karen Augustine-Rauch

T4-mediated rescue of aortic malformations in hypothyroid rats indicates maternal thyroid status can affect great vessel development.

Toxicology and applied pharmacology

Avec: Karen Augustine-Rauch , Jiin-Jia Liaw , Michael Graziano

Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGFβR1 Inhibitor as an Immuno-oncology Agent.

ACS medicinal chemistry letters

Avec: Upender Velaparthi , Chetan Padmakar Darne , Jayakumar Warrier , Peiying Liu , Hasibur Rahaman , Karen Augustine-Rauch , Karen Parrish , Zheng Yang , Jesse Swanson , Jennifer Brown , Gopal Dhar , Aravind Anandam , Vinay K Holenarsipur , Kamalavenkatesh Palanisamy , Barri S Wautlet , Mark P Fereshteh , Jonathan Lippy , Andrew J Tebben , Steven Sheriff , Max Ruzanov , Chunhong Yan , Anuradha Gupta , Arun Kumar Gupta , Muthalagu Vetrichelvan , Arvind Mathur , Marina Gelman , Rajinder Singh , Todd Kinsella , Anwar Murtaza , Joseph Fargnoli , Gregory Vite , Robert M Borzilleri

Intermittent dosing of the transforming growth factor beta receptor 1 inhibitor, BMS-986260, mitigates class-based cardiovascular toxicity in dogs but not rats.

Journal of applied toxicology : JAT

Avec: Gregory D Rak , Melvin R White , Karen Augustine-Rauch , Courtni Newsome , Michael J Graziano , Gene E Schulze

Réseau de co-auteurs

Jesse Swanson 2 collaborations

Anwar Murtaza 2 collaborations

Zheng Yang 2 collaborations

Robert Borzilleri 2 collaborations

Kamalavenkatesh Palanisamy 2 collaborations

Vinay K Holenarsipur 2 collaborations

Yong Zhang 1 collaboration

Karen E Parrish 1 collaboration

David R Tortolani 1 collaboration

Michael A Poss 1 collaboration

Audris Huang 1 collaboration

Honghe Wan 1 collaboration

Ashok V Purandare 1 collaboration

Andrew F Donnell 1 collaboration

James Kempson 1 collaboration

Xiaoping Hou 1 collaboration

Joseph Pawluczyk 1 collaboration

Shiuhang Yip 1 collaboration

Emily Luk 1 collaboration

Nimmi Raghavan 1 collaboration

James Smalley 1 collaboration

Louis J Lombardo 1 collaboration

M McNerney 1 collaboration

D Potter 1 collaboration

K Augustine-Rauch 1 collaboration

P Barrow 1 collaboration

B Beyer 1 collaboration

K Brannen 1 collaboration

S Engel 1 collaboration

B P Enright 1 collaboration

W S Nowland 1 collaboration

N Powles-Glover 1 collaboration

S Powlin 1 collaboration

M J Schneidkraut 1 collaboration

D Stanislaus 1 collaboration

K Turner 1 collaboration

M Graziano 1 collaboration

Faye Wang 1 collaboration

Cindy Zhang 1 collaboration

Jae Kwagh 1 collaboration

Brian Strassle 1 collaboration

Jinqing Li 1 collaboration

Minxue Huang 1 collaboration

Yunling Song 1 collaboration

Brenda Lehman 1 collaboration

Richard Westhouse 1 collaboration

Jiin-Jia Liaw 1 collaboration

Michael Graziano 1 collaboration

Upender Velaparthi 1 collaboration

Chetan Padmakar Darne 1 collaboration

Jayakumar Warrier 1 collaboration

Peiying Liu 1 collaboration

Hasibur Rahaman 1 collaboration

Karen Parrish 1 collaboration

Jennifer Brown 1 collaboration

Gopal Dhar 1 collaboration

Aravind Anandam 1 collaboration

Barri S Wautlet 1 collaboration

Mark P Fereshteh 1 collaboration

Jonathan Lippy 1 collaboration

Andrew J Tebben 1 collaboration

Steven Sheriff 1 collaboration

Max Ruzanov 1 collaboration

Chunhong Yan 1 collaboration

Anuradha Gupta 1 collaboration

Arun Kumar Gupta 1 collaboration

Muthalagu Vetrichelvan 1 collaboration

Arvind Mathur 1 collaboration

Marina Gelman 1 collaboration

Rajinder Singh 1 collaboration

Todd Kinsella 1 collaboration

Joseph Fargnoli 1 collaboration

Gregory Vite 1 collaboration

Robert M Borzilleri 1 collaboration

Gregory D Rak 1 collaboration

Melvin R White 1 collaboration

Courtni Newsome 1 collaboration

Michael J Graziano 1 collaboration

Gene E Schulze 1 collaboration