Katrin Rittinger

Affiliations

Molecular Structure of Cell Signalling Laboratory, The Francis Crick Institute, London, UK katrin.rittinger@crick.ac.uk.

ORCID: 0000-0002-7698-4435

Publications (14)

Characterisation of class VI TRIM RING domains: linking RING activity to C-terminal domain identity.

Life science alliance

Avec: Rebecca V Stevens , Diego Esposito , Katrin Rittinger

The molecular dissection of TRIM25's RNA-binding mechanism provides key insights into its antiviral activity.

Nature communications

Avec: Lucía Álvarez , Kevin Haubrich , Louisa Iselin , Laurent Gillioz , Vincenzo Ruscica , Karine Lapouge , Sandra Augsten , Ina Huppertz , Nila Roy Choudhury , Bernd Simon , Pawel Masiewicz , Mathilde Lethier , Stephen Cusack , Katrin Rittinger , Frank Gabel , Alexander Leitner , Gracjan Michlewski , Matthias W Hentze , Frédéric H T Allain , Alfredo Castello , Janosch Hennig

Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases.

Cell chemical biology

Avec: Yi-Chun Isabella Tsai , Henrik Johansson , David Dixon , Stephen Martin , Chun-Wa Chung , Jane Clarkson , David House , Katrin Rittinger

Does it take two to tango? RING domain self-association and activity in TRIM E3 ubiquitin ligases.

Biochemical Society transactions

Avec: Filippo Fiorentini , Diego Esposito , Katrin Rittinger

Characterisation of HOIP RBR E3 ligase conformational dynamics using integrative modelling.

Scientific reports

Avec: Marius Kausas , Diego Esposito , Katrin Rittinger , Franca Fraternali

Profiling Sulfur(VI) Fluorides as Reactive Functionalities for Chemical Biology Tools and Expansion of the Ligandable Proteome.

ACS chemical biology

Avec: Katharine E Gilbert , Aini Vuorinen , Arron Aatkar , Peter Pogány , Jonathan Pettinger , Emma K Grant , Joanna M Kirkpatrick , Katrin Rittinger , David House , Glenn A Burley , Jacob T Bush

The

Science signaling

Avec: Jens Meschede , Maria Šadić , Nikolas Furthmann , Tim Miedema , Dominik A Sehr , A Kathrin Müller-Rischart , Verian Bader , Lena A Berlemann , Anna Pilsl , Anita Schlierf , Katalin Barkovits , Barbara Kachholz , Katrin Rittinger , Fumiyo Ikeda , Katrin Marcus , Liliana Schaefer , Jörg Tatzelt , Konstanze F Winklhofer

Targeting the ubiquitin system by fragment-based drug discovery.

Frontiers in molecular biosciences

Avec: Cassandra Kennedy , Katherine McPhie , Katrin Rittinger

Divergent self-association properties of paralogous proteins TRIM2 and TRIM3 regulate their E3 ligase activity.

Nature communications

Avec: Diego Esposito , Jane Dudley-Fraser , Acely Garza-Garcia , Katrin Rittinger

Efficient Ligand Discovery Using Sulfur(VI) Fluoride Reactive Fragments.

ACS chemical biology

Avec: Arron Aatkar , Aini Vuorinen , Oliver E Longfield , Katharine Gilbert , Rachel Peltier-Heap , Craig D Wagner , Francesca Zappacosta , Katrin Rittinger , Chun-Wa Chung , David House , Nicholas C O Tomkinson , Jacob T Bush

Structural basis for ubiquitylation by HOIL-1.

Frontiers in molecular biosciences

Avec: Qilong Wu , Marios G Koliopoulos , Katrin Rittinger , Benjamin Stieglitz

Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP.

Journal of the American Chemical Society

Avec: Henrik Johansson , Yi-Chun Isabella Tsai , Ken Fantom , Chun-Wa Chung , Sandra Kümper , Luigi Martino , Daniel A Thomas , H Christian Eberl , Marcel Muelbaier , David House , Katrin Rittinger

It's a TRIM-endous view from the top: the varied roles of TRIpartite Motif proteins in brain development and disease.

Frontiers in molecular neuroscience

Avec: Jane Dudley-Fraser , Katrin Rittinger

Covalent fragment-based drug discovery for target tractability.

Current opinion in structural biology

Avec: William J McCarthy , Antonie J van der Zouwen , Jacob T Bush , Katrin Rittinger

Réseau de co-auteurs

Diego Esposito 4 collaborations

David House 4 collaborations

Chun-Wa Chung 3 collaborations

Jacob T Bush 3 collaborations

Yi-Chun Isabella Tsai 2 collaborations

Henrik Johansson 2 collaborations

Aini Vuorinen 2 collaborations

Arron Aatkar 2 collaborations

Jane Dudley-Fraser 2 collaborations

Rebecca V Stevens 1 collaboration

Lucía Álvarez 1 collaboration

Kevin Haubrich 1 collaboration

Louisa Iselin 1 collaboration

Laurent Gillioz 1 collaboration

Vincenzo Ruscica 1 collaboration

Karine Lapouge 1 collaboration

Sandra Augsten 1 collaboration

Ina Huppertz 1 collaboration

Nila Roy Choudhury 1 collaboration

Bernd Simon 1 collaboration

Pawel Masiewicz 1 collaboration

Mathilde Lethier 1 collaboration

Stephen Cusack 1 collaboration

Frank Gabel 1 collaboration

Alexander Leitner 1 collaboration

Gracjan Michlewski 1 collaboration

Matthias W Hentze 1 collaboration

Frédéric H T Allain 1 collaboration

Alfredo Castello 1 collaboration

Janosch Hennig 1 collaboration

David Dixon 1 collaboration

Stephen Martin 1 collaboration

Jane Clarkson 1 collaboration

Filippo Fiorentini 1 collaboration

Marius Kausas 1 collaboration

Franca Fraternali 1 collaboration

Katharine E Gilbert 1 collaboration

Peter Pogány 1 collaboration

Jonathan Pettinger 1 collaboration

Emma K Grant 1 collaboration

Joanna M Kirkpatrick 1 collaboration

Glenn A Burley 1 collaboration

Jens Meschede 1 collaboration

Maria Šadić 1 collaboration

Nikolas Furthmann 1 collaboration

Tim Miedema 1 collaboration

Dominik A Sehr 1 collaboration

A Kathrin Müller-Rischart 1 collaboration

Verian Bader 1 collaboration

Lena A Berlemann 1 collaboration

Anna Pilsl 1 collaboration

Anita Schlierf 1 collaboration

Katalin Barkovits 1 collaboration

Barbara Kachholz 1 collaboration

Fumiyo Ikeda 1 collaboration

Katrin Marcus 1 collaboration

Liliana Schaefer 1 collaboration

Jörg Tatzelt 1 collaboration

Konstanze F Winklhofer 1 collaboration

Cassandra Kennedy 1 collaboration

Katherine McPhie 1 collaboration

Acely Garza-Garcia 1 collaboration

Oliver E Longfield 1 collaboration

Katharine Gilbert 1 collaboration

Rachel Peltier-Heap 1 collaboration

Craig D Wagner 1 collaboration

Francesca Zappacosta 1 collaboration

Nicholas C O Tomkinson 1 collaboration

Qilong Wu 1 collaboration

Marios G Koliopoulos 1 collaboration

Benjamin Stieglitz 1 collaboration

Ken Fantom 1 collaboration

Sandra Kümper 1 collaboration

Luigi Martino 1 collaboration

Daniel A Thomas 1 collaboration

H Christian Eberl 1 collaboration

Marcel Muelbaier 1 collaboration

William J McCarthy 1 collaboration

Antonie J van der Zouwen 1 collaboration