Kirby N Swatek

Affiliations

Protein and Nucleic Acid Chemistry Division, Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom.
Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, Germany.

ORCID: 0000-0003-0634-3592

Publications (8)

Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppression.

PLoS pathogens

Avec: Linda J Visser , Chiara Aloise , Kirby N Swatek , Gisselle N Medina , Karin M Olek , Huib H Rabouw , Raoul J de Groot , Martijn A Langereis , Teresa de Los Santos , David Komander , Tim Skern , Frank J M van Kuppeveld

Decoding

Plants (Basel, Switzerland)

Avec: Nagib Ahsan , Amr R A Kataya , R Shyama Prasad Rao , Kirby N Swatek , Rashaun S Wilson , Louis J Meyer , Alejandro Tovar-Mendez , Severin Stevenson , Justyna Maszkowska , Grazyna Dobrowolska , Qiuming Yao , Dong Xu , Jay J Thelen

Insights into the ISG15 transfer cascade by the UBE1L activating enzyme.

Nature communications

Avec: Iona Wallace , Kheewoong Baek , J Rajan Prabu , Ronnald Vollrath , Susanne von Gronau , Brenda A Schulman , Kirby N Swatek

Insights into ubiquitin chain architecture using Ub-clipping.

Nature

Avec: Kirby N Swatek , Joanne L Usher , Anja F Kueck , Christina Gladkova , Tycho E T Mevissen , Jonathan N Pruneda , Tim Skern , David Komander

OTULIN deficiency in ORAS causes cell type-specific LUBAC degradation, dysregulated TNF signalling and cell death.

EMBO molecular medicine

Avec: Rune Busk Damgaard , Paul R Elliott , Kirby N Swatek , Eamonn R Maher , Polina Stepensky , Orly Elpeleg , David Komander , Yackov Berkun

The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules.

Cell host & microbe

Avec: Eric Alix , Camilla Godlee , Ondrej Cerny , Samkeliso Blundell , Romina Tocci , Sophie Matthews , Mei Liu , Jonathan N Pruneda , Kirby N Swatek , David Komander , Tabitha Sleap , David W Holden

Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling.

Molecular cell

Avec: Alban Ordureau , Joao A Paulo , Jiuchun Zhang , Heeseon An , Kirby N Swatek , Joe R Cannon , Qiaoqiao Wan , David Komander , J Wade Harper

ISGylation-independent protection of cell growth by USP18 following interferon stimulation.

The Biochemical journal

Avec: Anne Clancy , Emma V Rusilowicz-Jones , Iona Wallace , Kirby N Swatek , Sylvie Urbé , Michael J Clague

Réseau de co-auteurs

David Komander 5 collaborations

Tim Skern 2 collaborations

Iona Wallace 2 collaborations

Jonathan N Pruneda 2 collaborations

Linda J Visser 1 collaboration

Chiara Aloise 1 collaboration

Gisselle N Medina 1 collaboration

Karin M Olek 1 collaboration

Huib H Rabouw 1 collaboration

Raoul J de Groot 1 collaboration

Martijn A Langereis 1 collaboration

Teresa de Los Santos 1 collaboration

Frank J M van Kuppeveld 1 collaboration

Nagib Ahsan 1 collaboration

Amr R A Kataya 1 collaboration

R Shyama Prasad Rao 1 collaboration

Rashaun S Wilson 1 collaboration

Louis J Meyer 1 collaboration

Alejandro Tovar-Mendez 1 collaboration

Severin Stevenson 1 collaboration

Justyna Maszkowska 1 collaboration

Grazyna Dobrowolska 1 collaboration

Qiuming Yao 1 collaboration

Dong Xu 1 collaboration

Jay J Thelen 1 collaboration

Kheewoong Baek 1 collaboration

J Rajan Prabu 1 collaboration

Ronnald Vollrath 1 collaboration

Susanne von Gronau 1 collaboration

Brenda A Schulman 1 collaboration

Joanne L Usher 1 collaboration

Anja F Kueck 1 collaboration

Christina Gladkova 1 collaboration

Tycho E T Mevissen 1 collaboration

Rune Busk Damgaard 1 collaboration

Paul R Elliott 1 collaboration

Eamonn R Maher 1 collaboration

Polina Stepensky 1 collaboration

Orly Elpeleg 1 collaboration

Yackov Berkun 1 collaboration

Eric Alix 1 collaboration

Camilla Godlee 1 collaboration

Ondrej Cerny 1 collaboration

Samkeliso Blundell 1 collaboration

Romina Tocci 1 collaboration

Sophie Matthews 1 collaboration

Mei Liu 1 collaboration

Tabitha Sleap 1 collaboration

David W Holden 1 collaboration

Alban Ordureau 1 collaboration

Joao A Paulo 1 collaboration

Jiuchun Zhang 1 collaboration

Heeseon An 1 collaboration

Joe R Cannon 1 collaboration

Qiaoqiao Wan 1 collaboration

J Wade Harper 1 collaboration

Anne Clancy 1 collaboration

Emma V Rusilowicz-Jones 1 collaboration

Sylvie Urbé 1 collaboration

Michael J Clague 1 collaboration