Libor Macurek

Affiliations

Laboratory of Cancer Cell Biology, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Prague, Czech Republic.

Publications (24)

Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1.

Life science alliance

Avec: Helena Silva Cascales , Kamila Burdova , Anna Middleton , Vladislav Kuzin , Erik Müllers , Henriette Stoy , Laura Baranello , Libor Macurek , Arne Lindqvist

A novel assay for screening WIP1 phosphatase substrates in nuclear extracts.

The FEBS journal

Avec: Radka Storchova , Kamila Burdova , Matous Palek , René H Medema , Libor Macurek

Importance of Germline and Somatic Alterations in Human

International journal of molecular sciences

Avec: Barbora Otahalova , Zuzana Volkova , Jana Soukupova , Petra Kleiblova , Marketa Janatova , Michal Vocka , Libor Macurek , Zdenek Kleibl

PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.

Molecular oncology

Avec: Andra S Martinikova , Miroslav Stoyanov , Anna Oravetzova , Yannick P Kok , Shibo Yu , Jana Dobrovolna , Pavel Janscak , Marcel van Vugt , Libor Macurek

Cells

Avec: Lenka Stolarova , Petra Kleiblova , Marketa Janatova , Jana Soukupova , Petra Zemankova , Libor Macurek , Zdenek Kleibl

Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6.

Cells

Avec: Cecilia Aquino Perez , Matous Palek , Lenka Stolarova , Patrick von Morgen , Libor Macurek

Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma.

Cells

Avec: Andra S Martinikova , Monika Burocziova , Miroslav Stoyanov , Libor Macurek

CDC25B is required for the metaphase I-metaphase II transition in mouse oocytes.

Journal of cell science

Avec: Ivana Ferencova , Michaela Vaskovicova , David Drutovic , Lucie Knoblochova , Libor Macurek , Richard M Schultz , Petr Solc

Truncated PPM1D impairs stem cell response to genotoxic stress and promotes growth of APC-deficient tumors in the mouse colon.

Cell death & disease

Avec: Monika Burocziova , Kamila Burdova , Andra S Martinikova , Petr Kasparek , Petra Kleiblova , Stine A Danielsen , Marianna Borecka , Gabriela Jenikova , Lucie Janečková , Jozef Pavel , Petra Zemankova , Michaela Schneiderova , Lucie Schwarzova , Ivana Ticha , Xiao-Feng Sun , Katerina Jiraskova , Vaclav Liska , Ludmila Vodickova , Pavel Vodicka , Radislav Sedlacek , Zdenek Kleibl , Ragnhild A Lothe , Vladimír Korinek , Libor Macurek

WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors.

Cells

Avec: Kamila Burdova , Radka Storchova , Matous Palek , Libor Macurek

Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres.

Nucleic acids research

Avec: Radka Storchova , Matous Palek , Natalie Palkova , Pavel Veverka , Tomas Brom , Ctirad Hofr , Libor Macurek

FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Cecilia Aquino-Perez , Mahira Safaralizade , Roman Podhajecky , Hong Wang , Zdenek Lansky , Robert Grosse , Libor Macurek

RAD18 directs DNA double-strand break repair by homologous recombination to post-replicative chromatin.

Nucleic acids research

Avec: Matous Palek , Natalie Palkova , Auteur inconnu , Petra Kleiblova , Zdenek Kleibl , Libor Macurek

A comprehensive evaluation of pathogenic mutations in primary cutaneous melanomas, including the identification of novel loss-of-function variants.

Scientific reports

Avec: Ivana Ticha , Jan Hojny , Romana Michalkova , Ondrej Kodet , Eva Krkavcova , Nikola Hajkova , Kristyna Nemejcova , Michaela Bartu , Radek Jaksa , Miroslav Dura , Madiha Kanwal , Andra S Martinikova , Libor Macurek , Petra Zemankova , Zdenek Kleibl , Pavel Dundr

Multigene Panel Germline Testing of 1333 Czech Patients with Ovarian Cancer.

Cancers

Avec: Klara Lhotova , Lenka Stolarova , Petra Zemankova , Michal Vocka , Marketa Janatova , Marianna Borecka , Marta Cerna , Sandra Jelinkova , Jan Kral , Zuzana Volkova , Marketa Urbanova , Petra Kleiblova , Eva Machackova , Lenka Foretova , Jana Hazova , Petra Vasickova , Filip Lhota , Monika Koudova , Leona Cerna , Spiros Tavandzis , Jana Indrakova , Lucie Hruskova , Marcela Kosarova , Radek Vrtel , Viktor Stranecky , Stanislav Kmoch , Michal Zikan , Libor Macurek , Zdenek Kleibl , Jana Soukupova

CK1-mediated phosphorylation of FAM110A promotes its interaction with mitotic spindle and controls chromosomal alignment.

EMBO reports

Avec: Cecilia Aquino Perez , Monika Burocziova , Gabriela Jenikova , Libor Macurek

ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Lenka Stolarova , Petra Kleiblova , Petra Zemankova , Barbora Stastna , Marketa Janatova , Jana Soukupova , Maria Isabel Achatz , Christine Ambrosone , Paraskevi Apostolou , Banu K Arun , Paul Auer , Mollie Barnard , Birgitte Bertelsen , Auteur inconnu , Marinus J Blok , Nicholas Boddicker , Joan Brunet , Elizabeth S Burnside , Mariarosaria Calvello , Ian Campbell , Sock Hoai Chan , Fei Chen , Jian Bang Chiang , Anna Coppa , Laura Cortesi , Ana Crujeiras-González , Auteur inconnu , Kim De Leeneer , Robin De Putter , Allison DePersia , Lisa Devereux , Susan Domchek , Anna Efremidis , Christoph Engel , Corinna Ernst , D Gareth R Evans , Lidia Feliubadaló , Florentia Fostira , Olivia Fuentes-Ríos , Encarna B Gómez-García , Sara González , Christopher Haiman , Thomas van Overeem Hansen , Jan Hauke , James Hodge , Chunling Hu , Hongyan Huang , Nur Diana Binte Ishak , Yusuke Iwasaki , Irene Konstantopoulou , Peter Kraft , James Lacey , Conxi Lázaro , Na Li , Weng Khong Lim , Sara Lindstrom , Adriana Lori , Elana Martinez , Alexandra Martins , Koichi Matsuda , Giuseppe Matullo , Simone McInerny , Kyriaki Michailidou , Marco Montagna , Alvaro N A Monteiro , Luigi Mori , Katherine Nathanson , Susan L Neuhausen , Heli Nevanlinna , Janet E Olson , Julie Palmer , Barbara Pasini , Alpa Patel , Maria Piane , Bruce Poppe , Paolo Radice , Alessandra Renieri , Nicoletta Resta , Marcy E Richardson , Toon Rosseel , Kathryn J Ruddy , Marta Santamariña , Elizabeth Santana Dos Santos , Lauren Teras , Amanda E Toland , Amy Trentham-Dietz , Celine M Vachon , Alexander E Volk , Nana Weber-Lassalle , Jeffrey N Weitzel , Lisa Wiesmuller , Stacey Winham , Siddhartha Yadav , Drakoulis Yannoukakos , Song Yao , Valentina Zampiga , Magnus Zethoven , Ze Wen Zhang , Tomas Zima , Amanda B Spurdle , Ana Vega , Maria Rossing , Jesús Del Valle , Arcangela De Nicolo , Eric Hahnen , Kathleen B M Claes , Joanne Ngeow , Yukihide Momozawa , Paul A James , Fergus J Couch , Libor Macurek , Zdenek Kleibl

A comprehensive study evaluating germline FANCG variants in predisposition to breast and ovarian cancer.

Cancer medicine

Avec: Jana Soukupova , Barbora Stastna , Madiha Kanwal , Jan Hojny , Petra Zemankova , Marianna Borecka , Leona Cerna , Marta Cerna , Monika Cerna , Vaclava Curtisova , Tatana Dolezalova , Petra Duskova , Lenka Foretova , Ondrej Havranek , Klara Horackova , Milena Hovhannisyan , Lucie Hruskova , Stepan Chvojka , Marketa Janatova , Maria Janikova , Sandra Jelinkova , Pavel Just , Marta Kalousova , Petra Kleiblova , Marcela Kosarova , Monika Koudova , Jan Kral , Michaela Krausova , Vera Krutilkova , Eva Machackova , Katerina Matejkova , Renata Michalovska , Petr Nehasil , Barbora Nemcova , Jan Novotny , Matous Palek , Pavel Pesek , Marketa Safarikova , Ondrej Scheinost , Drahomira Springer , Lenka Stolarova , Viktor Stranecky , Ivan Subrt , Spiros Tavandzis , Eva Tureckova , Kamila Vesela , Zdenka Vlckova , Michal Vocka , Tomas Zima , Libor Macurek , Zdenek Kleibl , Auteur inconnu

p21 limits S phase DNA damage caused by the Wee1 inhibitor MK1775.

Cell cycle (Georgetown, Tex.)

Avec: Sissel Hauge , Libor Macurek , Randi G Syljuåsen

Identification of deleterious germline CHEK2 mutations and their association with breast and ovarian cancer.

International journal of cancer

Avec: Petra Kleiblova , Lenka Stolarova , Katerina Krizova , Filip Lhota , Jan Hojny , Petra Zemankova , Ondrej Havranek , Michal Vocka , Marta Cerna , Klara Lhotova , Marianna Borecka , Marketa Janatova , Jana Soukupova , Jan Sevcik , Martina Zimovjanova , Jaroslav Kotlas , Ales Panczak , Kamila Vesela , Jana Cervenkova , Michaela Schneiderova , Monika Burocziova , Kamila Burdova , Viktor Stranecky , Lenka Foretova , Eva Machackova , Spiros Tavandzis , Stanislav Kmoch , Libor Macurek , Zdenek Kleibl

Identification of Germline Mutations in Melanoma Patients with Early Onset, Double Primary Tumors, or Family Cancer History by NGS Analysis of 217 Genes.

Biomedicines

Avec: Lenka Stolarova , Sandra Jelinkova , Radka Storchova , Eva Machackova , Petra Zemankova , Michal Vocka , Ondrej Kodet , Jan Kral , Marta Cerna , Zuzana Volkova , Marketa Janatova , Jana Soukupova , Viktor Stranecky , Pavel Dundr , Lenka Foretova , Libor Macurek , Petra Kleiblova , Zdenek Kleibl

Ppm1d truncating mutations promote the development of genotoxic stress-induced AML.

Leukemia

Avec: Monika Burocziova , Petr Danek , Anna Oravetzova , Zuzana Chalupova , Meritxell Alberich-Jorda , Libor Macurek

Hematopoietic stem cell fate under the influence of Ser/Thr protein phosphatases.

Haematologica

Avec: Meritxell Alberich-Jorda , Libor Macurek

PPM1D activity promotes cellular transformation by preventing senescence and cell death.

Oncogene

Avec: Miroslav Stoyanov , Andra S Martinikova , Katerina Matejkova , Klara Horackova , Petra Zemankova , Kamila Burdova , Zuzana Zemanova , Petra Kleiblova , Zdenek Kleibl , Libor Macurek

Réseau de co-auteurs

Zdenek Kleibl 11 collaborations

Petra Kleiblova 10 collaborations

Petra Zemankova 9 collaborations

Jana Soukupova 7 collaborations

Marketa Janatova 7 collaborations

Lenka Stolarova 7 collaborations

Kamila Burdova 6 collaborations

Matous Palek 6 collaborations

Michal Vocka 5 collaborations

Andra S Martinikova 5 collaborations

Monika Burocziova 5 collaborations

Radka Storchova 4 collaborations

Marianna Borecka 4 collaborations

None None 4 collaborations

Marta Cerna 4 collaborations

Eva Machackova 4 collaborations

Lenka Foretova 4 collaborations

Viktor Stranecky 4 collaborations

Zuzana Volkova 3 collaborations

Miroslav Stoyanov 3 collaborations

Jan Hojny 3 collaborations

Sandra Jelinkova 3 collaborations

Jan Kral 3 collaborations

Spiros Tavandzis 3 collaborations

Anna Oravetzova 2 collaborations

Cecilia Aquino Perez 2 collaborations

Gabriela Jenikova 2 collaborations

Michaela Schneiderova 2 collaborations

Ivana Ticha 2 collaborations

Natalie Palkova 2 collaborations

Ondrej Kodet 2 collaborations

Madiha Kanwal 2 collaborations

Pavel Dundr 2 collaborations

Klara Lhotova 2 collaborations

Filip Lhota 2 collaborations

Monika Koudova 2 collaborations

Leona Cerna 2 collaborations

Lucie Hruskova 2 collaborations

Marcela Kosarova 2 collaborations

Stanislav Kmoch 2 collaborations

Barbora Stastna 2 collaborations

Tomas Zima 2 collaborations

Ondrej Havranek 2 collaborations

Klara Horackova 2 collaborations

Katerina Matejkova 2 collaborations

Kamila Vesela 2 collaborations

Meritxell Alberich-Jorda 2 collaborations

Helena Silva Cascales 1 collaboration

Anna Middleton 1 collaboration

Vladislav Kuzin 1 collaboration

Erik Müllers 1 collaboration

Henriette Stoy 1 collaboration

Laura Baranello 1 collaboration

Arne Lindqvist 1 collaboration

René H Medema 1 collaboration

Barbora Otahalova 1 collaboration

Yannick P Kok 1 collaboration

Shibo Yu 1 collaboration

Jana Dobrovolna 1 collaboration

Pavel Janscak 1 collaboration

Marcel van Vugt 1 collaboration

Patrick von Morgen 1 collaboration

Ivana Ferencova 1 collaboration

Michaela Vaskovicova 1 collaboration

David Drutovic 1 collaboration

Lucie Knoblochova 1 collaboration

Richard M Schultz 1 collaboration

Petr Solc 1 collaboration

Petr Kasparek 1 collaboration

Stine A Danielsen 1 collaboration

Lucie Janečková 1 collaboration

Jozef Pavel 1 collaboration

Lucie Schwarzova 1 collaboration

Xiao-Feng Sun 1 collaboration

Katerina Jiraskova 1 collaboration

Vaclav Liska 1 collaboration

Ludmila Vodickova 1 collaboration

Pavel Vodicka 1 collaboration

Radislav Sedlacek 1 collaboration

Ragnhild A Lothe 1 collaboration

Vladimír Korinek 1 collaboration

Pavel Veverka 1 collaboration

Tomas Brom 1 collaboration

Ctirad Hofr 1 collaboration

Cecilia Aquino-Perez 1 collaboration

Mahira Safaralizade 1 collaboration

Roman Podhajecky 1 collaboration

Hong Wang 1 collaboration

Zdenek Lansky 1 collaboration

Robert Grosse 1 collaboration

Romana Michalkova 1 collaboration

Eva Krkavcova 1 collaboration

Nikola Hajkova 1 collaboration

Kristyna Nemejcova 1 collaboration

Michaela Bartu 1 collaboration

Radek Jaksa 1 collaboration

Miroslav Dura 1 collaboration

Marketa Urbanova 1 collaboration

Jana Hazova 1 collaboration

Petra Vasickova 1 collaboration

Jana Indrakova 1 collaboration

Radek Vrtel 1 collaboration

Michal Zikan 1 collaboration

Maria Isabel Achatz 1 collaboration

Christine Ambrosone 1 collaboration

Paraskevi Apostolou 1 collaboration

Banu K Arun 1 collaboration

Paul Auer 1 collaboration

Mollie Barnard 1 collaboration

Birgitte Bertelsen 1 collaboration

Marinus J Blok 1 collaboration

Nicholas Boddicker 1 collaboration

Joan Brunet 1 collaboration

Elizabeth S Burnside 1 collaboration

Mariarosaria Calvello 1 collaboration

Ian Campbell 1 collaboration

Sock Hoai Chan 1 collaboration

Fei Chen 1 collaboration

Jian Bang Chiang 1 collaboration

Anna Coppa 1 collaboration

Laura Cortesi 1 collaboration

Ana Crujeiras-González 1 collaboration

Kim De Leeneer 1 collaboration

Robin De Putter 1 collaboration

Allison DePersia 1 collaboration

Lisa Devereux 1 collaboration

Susan Domchek 1 collaboration

Anna Efremidis 1 collaboration

Christoph Engel 1 collaboration

Corinna Ernst 1 collaboration

D Gareth R Evans 1 collaboration

Lidia Feliubadaló 1 collaboration

Florentia Fostira 1 collaboration

Olivia Fuentes-Ríos 1 collaboration

Encarna B Gómez-García 1 collaboration

Sara González 1 collaboration

Christopher Haiman 1 collaboration

Thomas van Overeem Hansen 1 collaboration

Jan Hauke 1 collaboration

James Hodge 1 collaboration

Chunling Hu 1 collaboration

Hongyan Huang 1 collaboration

Nur Diana Binte Ishak 1 collaboration

Yusuke Iwasaki 1 collaboration

Irene Konstantopoulou 1 collaboration

Peter Kraft 1 collaboration

James Lacey 1 collaboration

Conxi Lázaro 1 collaboration

Na Li 1 collaboration

Weng Khong Lim 1 collaboration

Sara Lindstrom 1 collaboration

Adriana Lori 1 collaboration

Elana Martinez 1 collaboration

Alexandra Martins 1 collaboration

Koichi Matsuda 1 collaboration

Giuseppe Matullo 1 collaboration

Simone McInerny 1 collaboration

Kyriaki Michailidou 1 collaboration

Marco Montagna 1 collaboration

Alvaro N A Monteiro 1 collaboration

Luigi Mori 1 collaboration

Katherine Nathanson 1 collaboration

Susan L Neuhausen 1 collaboration

Heli Nevanlinna 1 collaboration

Janet E Olson 1 collaboration

Julie Palmer 1 collaboration

Barbara Pasini 1 collaboration

Alpa Patel 1 collaboration

Maria Piane 1 collaboration

Bruce Poppe 1 collaboration

Paolo Radice 1 collaboration

Alessandra Renieri 1 collaboration

Nicoletta Resta 1 collaboration

Marcy E Richardson 1 collaboration

Toon Rosseel 1 collaboration

Kathryn J Ruddy 1 collaboration

Marta Santamariña 1 collaboration

Elizabeth Santana Dos Santos 1 collaboration

Lauren Teras 1 collaboration

Amanda E Toland 1 collaboration

Amy Trentham-Dietz 1 collaboration

Celine M Vachon 1 collaboration

Alexander E Volk 1 collaboration

Nana Weber-Lassalle 1 collaboration

Jeffrey N Weitzel 1 collaboration

Lisa Wiesmuller 1 collaboration

Stacey Winham 1 collaboration

Siddhartha Yadav 1 collaboration

Drakoulis Yannoukakos 1 collaboration

Song Yao 1 collaboration

Valentina Zampiga 1 collaboration

Magnus Zethoven 1 collaboration

Ze Wen Zhang 1 collaboration

Amanda B Spurdle 1 collaboration

Ana Vega 1 collaboration

Maria Rossing 1 collaboration

Jesús Del Valle 1 collaboration

Arcangela De Nicolo 1 collaboration

Eric Hahnen 1 collaboration

Kathleen B M Claes 1 collaboration

Joanne Ngeow 1 collaboration

Yukihide Momozawa 1 collaboration

Paul A James 1 collaboration

Fergus J Couch 1 collaboration

Monika Cerna 1 collaboration

Vaclava Curtisova 1 collaboration

Tatana Dolezalova 1 collaboration

Petra Duskova 1 collaboration

Milena Hovhannisyan 1 collaboration

Stepan Chvojka 1 collaboration

Maria Janikova 1 collaboration

Pavel Just 1 collaboration

Marta Kalousova 1 collaboration

Michaela Krausova 1 collaboration

Vera Krutilkova 1 collaboration

Renata Michalovska 1 collaboration

Petr Nehasil 1 collaboration

Barbora Nemcova 1 collaboration

Jan Novotny 1 collaboration

Pavel Pesek 1 collaboration

Marketa Safarikova 1 collaboration

Ondrej Scheinost 1 collaboration

Drahomira Springer 1 collaboration

Ivan Subrt 1 collaboration

Eva Tureckova 1 collaboration

Zdenka Vlckova 1 collaboration

Sissel Hauge 1 collaboration

Randi G Syljuåsen 1 collaboration

Katerina Krizova 1 collaboration

Jan Sevcik 1 collaboration

Martina Zimovjanova 1 collaboration

Jaroslav Kotlas 1 collaboration

Ales Panczak 1 collaboration

Jana Cervenkova 1 collaboration

Petr Danek 1 collaboration

Zuzana Chalupova 1 collaboration

Zuzana Zemanova 1 collaboration