Luca Simula

Affiliations

Dept. of Biology, University of Rome Tor Vergata, Rome, Italy; Dept. of Paediatric Haemato-Oncology, IRCCS Bambino Gesù Children Hospital, Rome, Italy.

Publications (20)

Targeting Drp1 and mitochondrial fission for therapeutic immune modulation.

Pharmacological research

Avec: Luca Simula , Michelangelo Campanella , Silvia Campello

Metabolic oscillations during cell-cycle progression.

Trends in endocrinology and metabolism: TEM

Avec: Philippe Icard , Luca Simula

The strategic roles of four enzymes in the interconnection between metabolism and oncogene activation in non-small cell lung cancer: Therapeutic implications.

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Avec: Philippe Icard , Luca Simula , Ludovic Fournel , Karen Leroy , Audrey Lupo , Diane Damotte , Marie Christine Charpentier , Catherine Durdux , Mauro Loi , Olivier Schussler , Guillaume Chassagnon , Antoine Coquerel , Hubert Lincet , Vincent De Pauw , Marco Alifano

Correction: JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction.

Cell death and differentiation

Avec: Luca Simula , Mauro Corrado , Benedetta Accordi , Anthea Di Rita , Francesca Nazio , Ylenia Antonucci , Arianna Di Daniele , Federico Caicci , Ignazio Caruana , Maria Eugenia Soriano , Martina Pigazzi , Franco Locatelli , Francesco Cecconi , Silvia Campello

FOXO1 Inhibition Generates Potent Nonactivated CAR T Cells against Solid Tumors.

Cancer immunology research

Avec: Maude Marchais , Luca Simula , Mélanie Phayanouvong , Fathia Mami-Chouaib , Georges Bismuth , Justine Decroocq , Didier Bouscary , Jacques Dutrieux , Marianne Mangeney

The dual role of citrate in cancer.

Biochimica et biophysica acta. Reviews on cancer

Avec: Philippe Icard , Luca Simula , Grit Zahn , Marco Alifano , Maria E Mycielska

Reversible induction of mitophagy by an optogenetic bimodular system.

Nature communications

Avec: Pasquale D'Acunzo , Flavie Strappazzon , Ignazio Caruana , Giacomo Meneghetti , Anthea Di Rita , Luca Simula , Gerrit Weber , Francesca Del Bufalo , Luisa Dalla Valle , Silvia Campello , Franco Locatelli , Francesco Cecconi

Immune Checkpoint Proteins, Metabolism and Adhesion Molecules: Overlooked Determinants of CAR T-Cell Migration?

Cells

Avec: Luca Simula , Emma Ollivier , Philippe Icard , Emmanuel Donnadieu

Following the Dynamism of the Mitochondrial Network in T Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Arianna Di Daniele , Luca Simula , Silvia Campello

PD-1-induced T cell exhaustion is controlled by a Drp1-dependent mechanism.

Molecular oncology

Avec: Luca Simula , Ylenia Antonucci , Giorgia Scarpelli , Valeria Cancila , Alessandra Colamatteo , Simona Manni , Biagio De Angelis , Concetta Quintarelli , Claudio Procaccini , Giuseppe Matarese , Claudio Tripodo , Silvia Campello

On the footsteps of Hippocrates, Sanctorius and Harvey to better understand the influence of cold on the occurrence of COVID-19 in European countries in 2020.

Biochimie

Avec: Philippe Icard , Luca Simula , Joana Rei , Ludovic Fournel , Vincent De Pauw , Marco Alifano

Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update.

International journal of molecular sciences

Avec: Philippe Icard , Antoine Coquerel , Zherui Wu , Joseph Gligorov , David Fuks , Ludovic Fournel , Hubert Lincet , Luca Simula

Why may citrate sodium significantly increase the effectiveness of transarterial chemoembolization in hepatocellular carcinoma?

Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy

Avec: Philippe Icard , Luca Simula , Zherui Wu , Diana Berzan , Philippe Sogni , Anthony Dohan , Raphael Dautry , Antoine Coquerel , Hubert Lincet , Mauro Loi , David Fuks

JNK1 and ERK1/2 modulate lymphocyte homeostasis via BIM and DRP1 upon AICD induction.

Cell death and differentiation

Thioridazine requires calcium influx to induce MLL-AF6-rearranged AML cell death.

Blood advances

Avec: Claudia Tregnago , Ambra Da Ros , Elena Porcù , Maddalena Benetton , Manuela Simonato , Luca Simula , Giulia Borella , Katia Polato , Sonia Minuzzo , Giulia Borile , Paola Cogo , Silvia Campello , Alessandro Massi , Romeo Romagnoli , Barbara Buldini , Franco Locatelli , Martina Pigazzi

Fructose-1,6-bisphosphate promotes PI3K and glycolysis in T cells?

Trends in endocrinology and metabolism: TEM

Avec: Philippe Icard , Marco Alifano , Emmanuel Donnadieu , Luca Simula

How Phosphofructokinase-1 Promotes PI3K and YAP/TAZ in Cancer: Therapeutic Perspectives.

Cancers

Avec: Luca Simula , Marco Alifano , Philippe Icard

The potential for citrate to reinforce epigenetic therapy by promoting apoptosis.

Trends in endocrinology and metabolism: TEM

Avec: Philippe Icard , Marco Alifano , Luca Simula

Mitochondrial metabolism sustains CD8

Nature communications

Avec: Luca Simula , Mattia Fumagalli , Lene Vimeux , Irena Rajnpreht , Philippe Icard , Gary Birsen , Dongjie An , Frédéric Pendino , Adrien Rouault , Nadège Bercovici , Diane Damotte , Audrey Lupo-Mansuet , Marco Alifano , Marie-Clotilde Alves-Guerra , Emmanuel Donnadieu

Hyaluronan-based hydrogel delivering glucose to mesenchymal stem cells intended to treat osteoarthritis.

International journal of pharmaceutics

Avec: Paula Gonzalez-Fernandez , Luca Simula , Sébastien Jenni , Olivier Jordan , Eric Allémann

Réseau de co-auteurs

Philippe Icard 11 collaborations

Silvia Campello 7 collaborations

Marco Alifano 7 collaborations

Franco Locatelli 4 collaborations

Ludovic Fournel 3 collaborations

Antoine Coquerel 3 collaborations

Hubert Lincet 3 collaborations

Anthea Di Rita 3 collaborations

Ylenia Antonucci 3 collaborations

Arianna Di Daniele 3 collaborations

Ignazio Caruana 3 collaborations

Martina Pigazzi 3 collaborations

Francesco Cecconi 3 collaborations

Emmanuel Donnadieu 3 collaborations

Diane Damotte 2 collaborations

Mauro Loi 2 collaborations

Vincent De Pauw 2 collaborations

Mauro Corrado 2 collaborations

Benedetta Accordi 2 collaborations

Francesca Nazio 2 collaborations

Federico Caicci 2 collaborations

Maria Eugenia Soriano 2 collaborations

Zherui Wu 2 collaborations

David Fuks 2 collaborations

Michelangelo Campanella 1 collaboration

Karen Leroy 1 collaboration

Audrey Lupo 1 collaboration

Marie Christine Charpentier 1 collaboration

Catherine Durdux 1 collaboration

Olivier Schussler 1 collaboration

Guillaume Chassagnon 1 collaboration

Maude Marchais 1 collaboration

Mélanie Phayanouvong 1 collaboration

Fathia Mami-Chouaib 1 collaboration

Georges Bismuth 1 collaboration

Justine Decroocq 1 collaboration

Didier Bouscary 1 collaboration

Jacques Dutrieux 1 collaboration

Marianne Mangeney 1 collaboration

Grit Zahn 1 collaboration

Maria E Mycielska 1 collaboration

Pasquale D'Acunzo 1 collaboration

Flavie Strappazzon 1 collaboration

Giacomo Meneghetti 1 collaboration

Gerrit Weber 1 collaboration

Francesca Del Bufalo 1 collaboration

Luisa Dalla Valle 1 collaboration

Emma Ollivier 1 collaboration

Giorgia Scarpelli 1 collaboration

Valeria Cancila 1 collaboration

Alessandra Colamatteo 1 collaboration

Simona Manni 1 collaboration

Biagio De Angelis 1 collaboration

Concetta Quintarelli 1 collaboration

Claudio Procaccini 1 collaboration

Giuseppe Matarese 1 collaboration

Claudio Tripodo 1 collaboration

Joana Rei 1 collaboration

Joseph Gligorov 1 collaboration

Diana Berzan 1 collaboration

Philippe Sogni 1 collaboration

Anthony Dohan 1 collaboration

Raphael Dautry 1 collaboration

Claudia Tregnago 1 collaboration

Ambra Da Ros 1 collaboration

Elena Porcù 1 collaboration

Maddalena Benetton 1 collaboration

Manuela Simonato 1 collaboration

Giulia Borella 1 collaboration

Katia Polato 1 collaboration

Sonia Minuzzo 1 collaboration

Giulia Borile 1 collaboration

Paola Cogo 1 collaboration

Alessandro Massi 1 collaboration

Romeo Romagnoli 1 collaboration

Barbara Buldini 1 collaboration

Mattia Fumagalli 1 collaboration

Lene Vimeux 1 collaboration

Irena Rajnpreht 1 collaboration

Gary Birsen 1 collaboration

Dongjie An 1 collaboration

Frédéric Pendino 1 collaboration

Adrien Rouault 1 collaboration

Nadège Bercovici 1 collaboration

Audrey Lupo-Mansuet 1 collaboration

Marie-Clotilde Alves-Guerra 1 collaboration

Paula Gonzalez-Fernandez 1 collaboration

Sébastien Jenni 1 collaboration

Olivier Jordan 1 collaboration

Eric Allémann 1 collaboration