Luca Tottone

Affiliations

Rutgers Cancer Institute of New Jersey, Rutgers University, New Brunswick, New Jersey.

ORCID: 0000-0002-1556-8649

Publications (6)

A Tumor Suppressor Enhancer of

Blood cancer discovery

Avec: Luca Tottone , Olga Lancho , Jui-Wan Loh , Amartya Singh , Shunsuke Kimura , Juliette Roels , Anna Kuchmiy , Steven Strubbe , Matthew A Lawlor , Victoria da Silva-Diz , Shirley Luo , Stéphanie Gachet , Carlos A García-Prieto , Rico Hagelaar , Manel Esteller , Jules P P Meijerink , Jean Soulier , Tom Taghon , Pieter Van Vlierberghe , Charles G Mullighan , Hossein Khiabanian , Pedro P Rocha , Daniel Herranz

Dietary glucosamine overcomes the defects in αβ-T cell ontogeny caused by the loss of de novo hexosamine biosynthesis.

Nature communications

Avec: Guy Werlen , Mei-Ling Li , Luca Tottone , Victoria da Silva-Diz , Xiaoyang Su , Daniel Herranz , Estela Jacinto

Histone Modifications Drive Aberrant Notch3 Expression/Activity and Growth in T-ALL.

Frontiers in oncology

Avec: Luca Tottone , Nadezda Zhdanovskaya , Álvaro Carmona Pestaña , Michele Zampieri , Fabrizio Simeoni , Sara Lazzari , Valeria Ruocco , Maria Pelullo , Paola Caiafa , Maria Pia Felli , Saula Checquolo , Diana Bellavia , Claudio Talora , Isabella Screpanti , Rocco Palermo

Tyrosine phosphorylation of CARM1 promotes its enzymatic activity and alters its target specificity.

Nature communications

Avec: Hidehiro Itonaga , Adnan K Mookhtiar , Sarah M Greenblatt , Fan Liu , Concepcion Martinez , Daniel Bilbao , Masai Rains , Pierre-Jacques Hamard , Jun Sun , Afoma C Umeano , Stephanie Duffort , Chuan Chen , Na Man , Gloria Mas , Luca Tottone , Tulasigeri Totiger , Terrence Bradley , Justin Taylor , Stephan Schürer , Stephen D Nimer

Notch3 contributes to T-cell leukemia growth via regulation of the unfolded protein response.

Oncogenesis

Avec: Maria Valeria Giuli , Giulia Diluvio , Eugenia Giuliani , Giulia Franciosa , Laura Di Magno , Maria Gemma Pignataro , Luca Tottone , Carmine Nicoletti , Zein Mersini Besharat , Giovanna Peruzzi , Maria Pelullo , Rocco Palermo , Gianluca Canettieri , Claudio Talora , Giulia d'Amati , Diana Bellavia , Isabella Screpanti , Saula Checquolo

A Therapeutically Targetable NOTCH1-SIRT1-KAT7 Axis in T-cell Leukemia.

Blood cancer discovery

Avec: Olga Lancho , Amartya Singh , Victoria da Silva-Diz , Maya Aleksandrova , Jesminara Khatun , Luca Tottone , Patricia Renck Nunes , Shirley Luo , Caifeng Zhao , Haiyan Zheng , Eric Chiles , Zhenyu Zuo , Pedro P Rocha , Xiaoyang Su , Hossein Khiabanian , Daniel Herranz

Réseau de co-auteurs

Victoria da Silva-Diz 3 collaborations

Daniel Herranz 3 collaborations

Olga Lancho 2 collaborations

Amartya Singh 2 collaborations

Shirley Luo 2 collaborations

Hossein Khiabanian 2 collaborations

Pedro P Rocha 2 collaborations

Xiaoyang Su 2 collaborations

Maria Pelullo 2 collaborations

Saula Checquolo 2 collaborations

Diana Bellavia 2 collaborations

Claudio Talora 2 collaborations

Isabella Screpanti 2 collaborations

Rocco Palermo 2 collaborations

Jui-Wan Loh 1 collaboration

Shunsuke Kimura 1 collaboration

Juliette Roels 1 collaboration

Anna Kuchmiy 1 collaboration

Steven Strubbe 1 collaboration

Matthew A Lawlor 1 collaboration

Stéphanie Gachet 1 collaboration

Carlos A García-Prieto 1 collaboration

Rico Hagelaar 1 collaboration

Manel Esteller 1 collaboration

Jules P P Meijerink 1 collaboration

Jean Soulier 1 collaboration

Tom Taghon 1 collaboration

Pieter Van Vlierberghe 1 collaboration

Charles G Mullighan 1 collaboration

Guy Werlen 1 collaboration

Mei-Ling Li 1 collaboration

Estela Jacinto 1 collaboration

Nadezda Zhdanovskaya 1 collaboration

Álvaro Carmona Pestaña 1 collaboration

Michele Zampieri 1 collaboration

Fabrizio Simeoni 1 collaboration

Sara Lazzari 1 collaboration

Valeria Ruocco 1 collaboration

Paola Caiafa 1 collaboration

Maria Pia Felli 1 collaboration

Hidehiro Itonaga 1 collaboration

Adnan K Mookhtiar 1 collaboration

Sarah M Greenblatt 1 collaboration

Fan Liu 1 collaboration

Concepcion Martinez 1 collaboration

Daniel Bilbao 1 collaboration

Masai Rains 1 collaboration

Pierre-Jacques Hamard 1 collaboration

Jun Sun 1 collaboration

Afoma C Umeano 1 collaboration

Stephanie Duffort 1 collaboration

Chuan Chen 1 collaboration

Na Man 1 collaboration

Gloria Mas 1 collaboration

Tulasigeri Totiger 1 collaboration

Terrence Bradley 1 collaboration

Justin Taylor 1 collaboration

Stephan Schürer 1 collaboration

Stephen D Nimer 1 collaboration

Maria Valeria Giuli 1 collaboration

Giulia Diluvio 1 collaboration

Eugenia Giuliani 1 collaboration

Giulia Franciosa 1 collaboration

Laura Di Magno 1 collaboration

Maria Gemma Pignataro 1 collaboration

Carmine Nicoletti 1 collaboration

Zein Mersini Besharat 1 collaboration

Giovanna Peruzzi 1 collaboration

Gianluca Canettieri 1 collaboration

Giulia d'Amati 1 collaboration

Maya Aleksandrova 1 collaboration

Jesminara Khatun 1 collaboration

Patricia Renck Nunes 1 collaboration

Caifeng Zhao 1 collaboration

Haiyan Zheng 1 collaboration

Eric Chiles 1 collaboration

Zhenyu Zuo 1 collaboration