Marco Macchia

Affiliations

Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126, Pisa, Italy.

Publications (14)

PSNCBAM-1 analogs: Structural evolutions and allosteric properties at cannabinoid CB1 receptor.

European journal of medicinal chemistry

Avec: Serena Meini , Francesca Gado , Lesley A Stevenson , Maria Digiacomo , Alessandro Saba , Simone Codini , Marco Macchia , Roger G Pertwee , Simone Bertini , Clementina Manera

Three-Dimensional Interactions Analysis of the Anticancer Target c-Src Kinase with Its Inhibitors.

Cancers

Avec: Vibhu Jha , Marco Macchia , Tiziano Tuccinardi , Giulio Poli

Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: implications for drug discovery.

Future medicinal chemistry

Avec: Francesca Gado , Serena Meini , Simone Bertini , Maria Digiacomo , Marco Macchia , Clementina Manera

New PIN1 inhibitors identified through a pharmacophore-driven, hierarchical consensus docking strategy.

Journal of enzyme inhibition and medicinal chemistry

Avec: Giulio Poli , Miriana Di Stefano , Joan Arias Estevez , Filippo Minutolo , Carlotta Granchi , Antonio Giordano , Salvatore Parisi , Matteo Mauceri , Vincenzo Canzonieri , Marco Macchia , Isabella Caligiuri , Tiziano Tuccinardi , Flavio Rizzolio

Discovery of Monoacylglycerol Lipase (MAGL) Inhibitors Based on a Pharmacophore-Guided Virtual Screening Study.

Molecules (Basel, Switzerland)

Avec: Vibhu Jha , Marzia Biagi , Valeria Spinelli , Miriana Di Stefano , Marco Macchia , Filippo Minutolo , Carlotta Granchi , Giulio Poli , Tiziano Tuccinardi

Medicinal Chemistry approach, pharmacology and neuroprotective benefits of CB

Pharmacological research

Avec: Rebecca Ferrisi , Costanza Ceni , Simone Bertini , Marco Macchia , Clementina Manera , Francesca Gado

Wound Dehiscence After Achilles Tendon Trauma and Repair: Treatment With Ultraportable Negative Pressure Wound Therapy and Compression Therapy.

Wounds : a compendium of clinical research and practice

Avec: Giulia Davini , Valentina Dini , Agata Janowska , Michela Macchia , Bruno Gualtieri , Giammarco Granieri , Marco Romanelli

Predicting potentially pathogenic effects of

Journal of enzyme inhibition and medicinal chemistry

Avec: Giulio Poli , Ivana Barravecchia , Gian Carlo Demontis , Andrea Sodi , Alessandro Saba , Stanislao Rizzo , Marco Macchia , Tiziano Tuccinardi

The phenolic compounds tyrosol and hydroxytyrosol counteract liver fibrogenesis via the transcriptional modulation of NADPH oxidases and oxidative stress-related miRNAs.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Avec: Daniela Gabbia , Sara Carpi , Samantha Sarcognato , Ilaria Zanotto , Katia Sayaf , Martina Colognesi , Beatrice Polini , Maria Digiacomo , Marco Macchia , Paola Nieri , Maria Carrara , Nora Cazzagon , Francesco Paolo Russo , Maria Guido , Sara De Martin

Design, synthesis, ADME and biological evaluation of benzylpiperidine and benzylpiperazine derivatives as novel reversible monoacylglycerol lipase (MAGL) inhibitors.

European journal of medicinal chemistry

Avec: Miriana Di Stefano , Samuele Masoni , Giulia Bononi , Giulio Poli , Salvatore Galati , Francesca Gado , Simone Manzi , Chiara Vagaggini , Annalaura Brai , Isabella Caligiuri , Kanwal Asif , Flavio Rizzolio , Marco Macchia , Andrea Chicca , Andrea Sodi , Valeria Di Bussolo , Filippo Minutolo , Philip Meier , Jürg Gertsch , Carlotta Granchi , Elena Dreassi , Tiziano Tuccinardi

WaSPred: A reliable AI-based water solubility predictor for small molecules.

International journal of pharmaceutics

Avec: Miriana Di Stefano , Salvatore Galati , Chiara Lonzi , Carlotta Granchi , Giulio Poli , Tiziano Tuccinardi , Marco Macchia

Comparative Analysis on Polyphenolic Composition of Different Olive Mill Wastewater and Related Extra Virgin Olive Oil Extracts and Evaluation of Nutraceutical Properties by Cell-Based Studies.

Foods (Basel, Switzerland)

Avec: Doretta Cuffaro , Andrea Bertolini , Ana Margarida Silva , Francisca Rodrigues , Daniela Gabbia , Sara De Martin , Alessandro Saba , Simone Bertini , Maria Digiacomo , Marco Macchia

Extensive Reliability Evaluation of Docking-Based Target-Fishing Strategies.

International journal of molecular sciences

Avec: Margherita Lapillo , Tiziano Tuccinardi , Adriano Martinelli , Marco Macchia , Antonio Giordano , Giulio Poli

Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors.

Journal of enzyme inhibition and medicinal chemistry

Avec: Giulio Poli , Margherita Lapillo , Vibhu Jha , Nayla Mouawad , Isabella Caligiuri , Marco Macchia , Filippo Minutolo , Flavio Rizzolio , Tiziano Tuccinardi , Carlotta Granchi

Réseau de co-auteurs

Tiziano Tuccinardi 8 collaborations

Giulio Poli 8 collaborations

Carlotta Granchi 5 collaborations

Francesca Gado 4 collaborations

Maria Digiacomo 4 collaborations

Simone Bertini 4 collaborations

Miriana Di Stefano 4 collaborations

Filippo Minutolo 4 collaborations

Alessandro Saba 3 collaborations

Clementina Manera 3 collaborations

Vibhu Jha 3 collaborations

Isabella Caligiuri 3 collaborations

Flavio Rizzolio 3 collaborations

Serena Meini 2 collaborations

Antonio Giordano 2 collaborations

Andrea Sodi 2 collaborations

Daniela Gabbia 2 collaborations

Sara De Martin 2 collaborations

Salvatore Galati 2 collaborations

Margherita Lapillo 2 collaborations

Lesley A Stevenson 1 collaboration

Simone Codini 1 collaboration

Roger G Pertwee 1 collaboration

Joan Arias Estevez 1 collaboration

Salvatore Parisi 1 collaboration

Matteo Mauceri 1 collaboration

Vincenzo Canzonieri 1 collaboration

Marzia Biagi 1 collaboration

Valeria Spinelli 1 collaboration

Rebecca Ferrisi 1 collaboration

Costanza Ceni 1 collaboration

Giulia Davini 1 collaboration

Valentina Dini 1 collaboration

Agata Janowska 1 collaboration

Michela Macchia 1 collaboration

Bruno Gualtieri 1 collaboration

Giammarco Granieri 1 collaboration

Marco Romanelli 1 collaboration

Ivana Barravecchia 1 collaboration

Gian Carlo Demontis 1 collaboration

Stanislao Rizzo 1 collaboration

Sara Carpi 1 collaboration

Samantha Sarcognato 1 collaboration

Ilaria Zanotto 1 collaboration

Katia Sayaf 1 collaboration

Martina Colognesi 1 collaboration

Beatrice Polini 1 collaboration

Paola Nieri 1 collaboration

Maria Carrara 1 collaboration

Nora Cazzagon 1 collaboration

Francesco Paolo Russo 1 collaboration

Maria Guido 1 collaboration

Samuele Masoni 1 collaboration

Giulia Bononi 1 collaboration

Simone Manzi 1 collaboration

Chiara Vagaggini 1 collaboration

Annalaura Brai 1 collaboration

Kanwal Asif 1 collaboration

Andrea Chicca 1 collaboration

Valeria Di Bussolo 1 collaboration

Philip Meier 1 collaboration

Jürg Gertsch 1 collaboration

Elena Dreassi 1 collaboration

Chiara Lonzi 1 collaboration

Doretta Cuffaro 1 collaboration

Andrea Bertolini 1 collaboration

Ana Margarida Silva 1 collaboration

Francisca Rodrigues 1 collaboration

Adriano Martinelli 1 collaboration

Nayla Mouawad 1 collaboration