Marianne G Rots

Affiliations

Epigenetic Editing, Dept. Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713, GZ, Groningen, The Netherlands.

Publications (15)

The timeline of epigenetic drug discovery: from reality to dreams.

Clinical epigenetics

Avec: A Ganesan , Paola B Arimondo , Marianne G Rots , Carmen Jeronimo , María Berdasco

Targeted epigenetic silencing of UCHL1 expression suppresses collagen-1 production in human lung epithelial cells.

Epigenetics

Avec: Dan-Dan Wu , Andy T Y Lau , Yan-Ming Xu , Marjan Reinders-Luinge , Mihaly Koncz , Antal Kiss , Wim Timens , Marianne G Rots , Machteld N Hylkema

Liver transcriptomic and methylomic analyses identify transcriptional mitogen-activated protein kinase regulation in facultative hibernation of Syrian hamster.

Proceedings. Biological sciences

Avec: Louis Coussement , Marloes M Oosterhof , Victor Guryev , Vera A Reitsema , Jojanneke J Bruintjes , Maaike Goris , Hjalmar R Bouma , Tim de Meyer , Marianne G Rots , Robert H Henning

Advances of epigenetic editing.

Current opinion in chemical biology

Avec: Rutger A F Gjaltema , Marianne G Rots

Plasmid Delivery and Single-Cell Plasmid Expression Analysis for CRISPR/dCas9-Based Epigenetic Editing.

Methods in molecular biology (Clifton, N.J.)

Avec: Anna C H van den Berg van Saparoea , Quint C van Loosen , Federica Sarno , Evgenia Ntini , Marianne G Rots , Rutger A F Gjaltema , Pernette J Verschure

KRAB-Induced Heterochromatin Effectively Silences

International journal of molecular sciences

Avec: Rutger A F Gjaltema , Désirée Goubert , Christian Huisman , Consuelo Del Pilar García Tobilla , Mihály Koncz , Pytrick G Jellema , Dandan Wu , Uilke Brouwer , Antal Kiss , Pernette J Verschure , Ruud A Bank , Marianne G Rots

The influence of eukaryotic chromatin state on CRISPR-Cas9 editing efficiencies.

Current opinion in biotechnology

Avec: Sebald An Verkuijl , Marianne G Rots

Ubiquitin carboxyl-terminal hydrolase isozyme L1/UCHL1 suppresses epithelial-mesenchymal transition and is under-expressed in cadmium-transformed human bronchial epithelial cells.

Cell biology and toxicology

Avec: Dan-Dan Wu , Yan-Ming Xu , De-Ju Chen , Zhan-Ling Liang , Xu-Li Chen , Machteld N Hylkema , Marianne G Rots , Sheng-Qing Li , Andy T Y Lau

The Endothelium as a Target for Anti-Atherogenic Therapy: A Focus on the Epigenetic Enzymes EZH2 and SIRT1.

Journal of personalized medicine

Avec: Jolien Fledderus , Byambasuren Vanchin , Marianne G Rots , Guido Krenning

Development of Locus-Directed Editing of the Epigenome from Basic Mechanistic Engineering to First Clinical Applications.

Methods in molecular biology (Clifton, N.J.)

Avec: Marianne G Rots , Albert Jeltsch

Folic acid conjugates of a bleomycin mimic for selective targeting of folate receptor positive cancer cells.

Bioorganic & medicinal chemistry letters

Avec: Arjan Geersing , Reinder H de Vries , Gerrit Jansen , Marianne G Rots , Gerard Roelfes

Epigenetic Regulation of S100A9 and S100A12 Expression in Monocyte-Macrophage System in Hyperglycemic Conditions.

Frontiers in immunology

Avec: Dieuwertje M Mossel , Kondaiah Moganti , Vladimir Riabov , Christel Weiss , Stefan Kopf , Julio Cordero , Gergana Dobreva , Marianne G Rots , Harald Klüter , Martin C Harmsen , Julia Kzhyshkowska

Mitochondrial GpC and CpG DNA Hypermethylation Cause Metabolic Stress-Induced Mitophagy and Cholestophagy.

International journal of molecular sciences

Avec: Claudia Theys , Joe Ibrahim , Ligia Mateiu , Archibold Mposhi , Laura García-Pupo , Tim De Pooter , Peter De Rijk , Mojca Strazisar , İkbal Agah İnce , Iuliana Vintea , Marianne G Rots , Wim Vanden Berghe

Generation of Cell Lines Stably Expressing a dCas9-Fusion or sgRNA to Address Dynamics of Long-Term Effects of Epigenetic Editing.

Methods in molecular biology (Clifton, N.J.)

Avec: Federica Sarno , Mihaly Koncz , Roos E Eilers , Pernette J Verschure , Marianne G Rots

Exploiting epigenetics for the treatment of inborn errors of metabolism.

Journal of inherited metabolic disease

Avec: Martijn G S Rutten , Marianne G Rots , Maaike H Oosterveer

Réseau de co-auteurs

Rutger A F Gjaltema 3 collaborations

Pernette J Verschure 3 collaborations

Dan-Dan Wu 2 collaborations

Andy T Y Lau 2 collaborations

Yan-Ming Xu 2 collaborations

Mihaly Koncz 2 collaborations

Antal Kiss 2 collaborations

Machteld N Hylkema 2 collaborations

Federica Sarno 2 collaborations

A Ganesan 1 collaboration

Paola B Arimondo 1 collaboration

Carmen Jeronimo 1 collaboration

María Berdasco 1 collaboration

Marjan Reinders-Luinge 1 collaboration

Wim Timens 1 collaboration

Louis Coussement 1 collaboration

Marloes M Oosterhof 1 collaboration

Victor Guryev 1 collaboration

Vera A Reitsema 1 collaboration

Jojanneke J Bruintjes 1 collaboration

Maaike Goris 1 collaboration

Hjalmar R Bouma 1 collaboration

Tim de Meyer 1 collaboration

Robert H Henning 1 collaboration

Anna C H van den Berg van Saparoea 1 collaboration

Quint C van Loosen 1 collaboration

Evgenia Ntini 1 collaboration

Désirée Goubert 1 collaboration

Christian Huisman 1 collaboration

Consuelo Del Pilar García Tobilla 1 collaboration

Mihály Koncz 1 collaboration

Pytrick G Jellema 1 collaboration

Dandan Wu 1 collaboration

Uilke Brouwer 1 collaboration

Ruud A Bank 1 collaboration

Sebald An Verkuijl 1 collaboration

De-Ju Chen 1 collaboration

Zhan-Ling Liang 1 collaboration

Xu-Li Chen 1 collaboration

Sheng-Qing Li 1 collaboration

Jolien Fledderus 1 collaboration

Byambasuren Vanchin 1 collaboration

Guido Krenning 1 collaboration

Albert Jeltsch 1 collaboration

Arjan Geersing 1 collaboration

Reinder H de Vries 1 collaboration

Gerrit Jansen 1 collaboration

Gerard Roelfes 1 collaboration

Dieuwertje M Mossel 1 collaboration

Kondaiah Moganti 1 collaboration

Vladimir Riabov 1 collaboration

Christel Weiss 1 collaboration

Stefan Kopf 1 collaboration

Julio Cordero 1 collaboration

Gergana Dobreva 1 collaboration

Harald Klüter 1 collaboration

Martin C Harmsen 1 collaboration

Julia Kzhyshkowska 1 collaboration

Claudia Theys 1 collaboration

Joe Ibrahim 1 collaboration

Ligia Mateiu 1 collaboration

Archibold Mposhi 1 collaboration

Laura García-Pupo 1 collaboration

Tim De Pooter 1 collaboration

Peter De Rijk 1 collaboration

Mojca Strazisar 1 collaboration

İkbal Agah İnce 1 collaboration

Iuliana Vintea 1 collaboration

Wim Vanden Berghe 1 collaboration

Roos E Eilers 1 collaboration

Martijn G S Rutten 1 collaboration

Maaike H Oosterveer 1 collaboration