Mark Throsby

Affiliations

Merus NV, Utrecht, The Netherlands. M.Throsby@merus.nl.

ORCID: 0000-0003-1352-3946

Publications (3)

Functional patient-derived organoid screenings identify MCLA-158 as a therapeutic EGFR × LGR5 bispecific antibody with efficacy in epithelial tumors.

Nature cancer

Avec: Bram Herpers , Berina Eppink , Mark I James , Carme Cortina , Adrià Cañellas-Socias , Sylvia F Boj , Xavier Hernando-Momblona , Dominik Glodzik , Rob C Roovers , Marc van de Wetering , Carina Bartelink-Clements , Vanessa Zondag-van der Zande , Jara García Mateos , Kuan Yan , Lucia Salinaro , Abdul Basmeleh , Szabolcs Fatrai , David Maussang , Jeroen J Lammerts van Bueren , Irene Chicote , Garazi Serna , Laia Cabellos , Lorena Ramírez , Paolo Nuciforo , Ramon Salazar , Cristina Santos , Alberto Villanueva , Camille Stephan-Otto Attolini , Elena Sancho , Hector G Palmer , Josep Tabernero , Michael R Stratton , John de Kruif , Ton Logtenberg , Hans Clevers , Leo S Price , Robert G J Vries , Eduard Batlle , Mark Throsby

Three-Dimensional Modeling of Solid Tumors and Their Microenvironment to Evaluate T Cell Therapy Efficacy In Vitro.

Journal of immunology (Baltimore, Md. : 1950)

Avec: Ronja Pscheid , Esther Drent , Judith Wienke , Josephine G M Strijker , Mark Throsby , Jan J Molenaar

A human CD137×PD-L1 bispecific antibody promotes anti-tumor immunity via context-dependent T cell costimulation and checkpoint blockade.

Nature communications

Avec: Cecile Geuijen , Paul Tacken , Liang-Chuan Wang , Rinse Klooster , Pieter Fokko van Loo , Jing Zhou , Arpita Mondal , Yao-Bin Liu , Arjen Kramer , Thomas Condamine , Alla Volgina , Linda J A Hendriks , Hans van der Maaden , Eric Rovers , Steef Engels , Floris Fransen , Renate den Blanken-Smit , Vanessa Zondag-van der Zande , Abdul Basmeleh , Willem Bartelink , Ashwini Kulkarni , Wilfred Marissen , Cheng-Yen Huang , Leslie Hall , Shane Harvey , Soyeon Kim , Marina Martinez , Shaun O'Brien , Edmund Moon , Steven Albelda , Chrysi Kanellopoulou , Shaun Stewart , Horacio Nastri , Alexander B H Bakker , Peggy Scherle , Ton Logtenberg , Gregory Hollis , John de Kruif , Reid Huber , Patrick A Mayes , Mark Throsby

Réseau de co-auteurs

Vanessa Zondag-van der Zande 2 collaborations

Abdul Basmeleh 2 collaborations

John de Kruif 2 collaborations

Ton Logtenberg 2 collaborations

Bram Herpers 1 collaboration

Berina Eppink 1 collaboration

Mark I James 1 collaboration

Carme Cortina 1 collaboration

Adrià Cañellas-Socias 1 collaboration

Sylvia F Boj 1 collaboration

Xavier Hernando-Momblona 1 collaboration

Dominik Glodzik 1 collaboration

Rob C Roovers 1 collaboration

Marc van de Wetering 1 collaboration

Carina Bartelink-Clements 1 collaboration

Jara García Mateos 1 collaboration

Kuan Yan 1 collaboration

Lucia Salinaro 1 collaboration

Szabolcs Fatrai 1 collaboration

David Maussang 1 collaboration

Jeroen J Lammerts van Bueren 1 collaboration

Irene Chicote 1 collaboration

Garazi Serna 1 collaboration

Laia Cabellos 1 collaboration

Lorena Ramírez 1 collaboration

Paolo Nuciforo 1 collaboration

Ramon Salazar 1 collaboration

Cristina Santos 1 collaboration

Alberto Villanueva 1 collaboration

Camille Stephan-Otto Attolini 1 collaboration

Elena Sancho 1 collaboration

Hector G Palmer 1 collaboration

Josep Tabernero 1 collaboration

Michael R Stratton 1 collaboration

Hans Clevers 1 collaboration

Leo S Price 1 collaboration

Robert G J Vries 1 collaboration

Eduard Batlle 1 collaboration

Ronja Pscheid 1 collaboration

Esther Drent 1 collaboration

Judith Wienke 1 collaboration

Josephine G M Strijker 1 collaboration

Jan J Molenaar 1 collaboration

Cecile Geuijen 1 collaboration

Paul Tacken 1 collaboration

Liang-Chuan Wang 1 collaboration

Rinse Klooster 1 collaboration

Pieter Fokko van Loo 1 collaboration

Jing Zhou 1 collaboration

Arpita Mondal 1 collaboration

Yao-Bin Liu 1 collaboration

Arjen Kramer 1 collaboration

Thomas Condamine 1 collaboration

Alla Volgina 1 collaboration

Linda J A Hendriks 1 collaboration

Hans van der Maaden 1 collaboration

Eric Rovers 1 collaboration

Steef Engels 1 collaboration

Floris Fransen 1 collaboration

Renate den Blanken-Smit 1 collaboration

Willem Bartelink 1 collaboration

Ashwini Kulkarni 1 collaboration

Wilfred Marissen 1 collaboration

Cheng-Yen Huang 1 collaboration

Leslie Hall 1 collaboration

Shane Harvey 1 collaboration

Soyeon Kim 1 collaboration

Marina Martinez 1 collaboration

Shaun O'Brien 1 collaboration

Edmund Moon 1 collaboration

Steven Albelda 1 collaboration

Chrysi Kanellopoulou 1 collaboration

Shaun Stewart 1 collaboration

Horacio Nastri 1 collaboration

Alexander B H Bakker 1 collaboration

Peggy Scherle 1 collaboration

Gregory Hollis 1 collaboration

Reid Huber 1 collaboration

Patrick A Mayes 1 collaboration