Matthias Frech

Affiliations

Discovery Technologies, Merck KGaA, Frankfurter Straße 250, 64293 Darmstadt, Germany.

Publications (14)

Targeting zonulin and intestinal epithelial barrier function to prevent onset of arthritis.

Nature communications

Avec: Narges Tajik , Michael Frech , Oscar Schulz , Fabian Schälter , Sébastien Lucas , Vugar Azizov , Kerstin Dürholz , Franziska Steffen , Yasunori Omata , Andreas Rings , Marko Bertog , Aroldo Rizzo , Aida Iljazovic , Marijana Basic , Arnd Kleyer , Stephan Culemann , Gerhard Krönke , Yubin Luo , Klaus Überla , Udo S Gaipl , Benjamin Frey , Till Strowig , Kerstin Sarter , Stephan C Bischoff , Stefan Wirtz , Juan D Cañete , Francesco Ciccia , Georg Schett , Mario M Zaiss

Type 2 innate lymphoid cells inhibit the differentiation of osteoclasts and protect from ovariectomy-induced bone loss.

Bone

Avec: Yasunori Omata , Michael Frech , Sébastien Lucas , Tatjana Primbs , Lisa Knipfer , Stefan Wirtz , Yuho Kadono , Taku Saito , Sakae Tanaka , Kerstin Sarter , Georg Schett , Mario M Zaiss

An in vivo gene delivery approach for the isolation of reasonable numbers of type 2 innate lymphoid cells.

MethodsX

Avec: Michael Frech , Lisa Knipfer , Stefan Wirtz , Mario M Zaiss

"My Goal Is to Lose 2.923 kg!"-Efficacy of Precise Versus Round Goals for Body Weight Reduction.

Frontiers in psychology

Avec: Marie-Lena Frech , Malte Friese , David D Loschelder

Acetate, a metabolic product of Heligmosomoides polygyrus, facilitates intestinal epithelial barrier breakdown in a FFAR2-dependent manner.

International journal for parasitology

Avec: Fabian Schälter , Michael Frech , Kerstin Dürholz , Sébastien Lucas , Kerstin Sarter , Luc Lebon , Julia Esser-von Bieren , Lalit K Dubey , David Voehringer , Georg Schett , Nicola L Harris , Mario M Zaiss

Novel therapies and innovation for systemic sclerosis skin ulceration.

Best practice & research. Clinical rheumatology

Avec: Tracy M Frech , Madeleine Frech , Inga Saknite , Katie A O'Connell , Shramana Ghosh , Justin Baba , Eric R Tkaczyk

Retinoid orphan receptor gamma t (rorγt) promotes inflammatory eosinophilia but is dispensable for innate immune-mediated colitis.

PloS one

Avec: Alvaro Torres-Huerta , Katelyn Ruley-Haase , Theodore Reed , Antonia Boger-May , Derek Rubadeux , Lauren Mayer , Arpitha Mysore Rajashekara , Morgan Hiller , Madeleine Frech , Connor Roncagli , Cameron Pedersen , Mary Catherine Camacho , Lauren Hollmer , Lauren English , Grace Kane , David L Boone

Ethanol consumption inhibits T

Nature communications

Avec: Vugar Azizov , Katharina Dietel , Franziska Steffen , Kerstin Dürholz , Julia Meidenbauer , Sébastien Lucas , Michael Frech , Yasunori Omata , Narges Tajik , Lisa Knipfer , Anne Kolenbrander , Silvia Seubert , Dennis Lapuente , Maria V Sokolova , Jörg Hofmann , Matthias Tenbusch , Andreas Ramming , Ulrike Steffen , Falk Nimmerjahn , Ralf Linker , Stefan Wirtz , Martin Herrmann , Vladimir Temchura , Kerstin Sarter , Georg Schett , Mario M Zaiss

Structure-kinetic relationship reveals the mechanism of selectivity of FAK inhibitors over PYK2.

Cell chemical biology

Avec: Benedict-Tilman Berger , Marta Amaral , Daria B Kokh , Ariane Nunes-Alves , Djordje Musil , Timo Heinrich , Martin Schröder , Rebecca Neil , Jing Wang , Iva Navratilova , Joerg Bomke , Jonathan M Elkins , Susanne Müller , Matthias Frech , Rebecca C Wade , Stefan Knapp

Optimized precursor to simplify assignment transfer between backbone resonances and stereospecifically labelled valine and leucine methyl groups: application to human Hsp90 N-terminal domain.

Journal of biomolecular NMR

Avec: Faustine Henot , Rime Kerfah , Ricarda Törner , Pavel Macek , Elodie Crublet , Pierre Gans , Matthias Frech , Olivier Hamelin , Jerome Boisbouvier

Butyrophilin 2a2 (Btn2a2) expression on thymic epithelial cells promotes central T cell tolerance and prevents autoimmune disease.

Journal of autoimmunity

Avec: Michael Frech , Heike Danzer , Pooja Uchil , Vugar Azizov , Eva Schmid , Fabian Schälter , Kerstin Dürholz , Daniele Mauro , Simon Rauber , Luis Muñoz , Leila Taher , Francesco Ciccia , Kilian Schober , Magali Irla , Kerstin Sarter , Georg Schett , Mario M Zaiss

A CARE-compliant article successful salvage of bilateral perinatal testicular torsion after delivery out of breech presentation: A case report and review of the literature.

Medicine

Avec: Vivienne Sommer-Jörgensen , Markus Künzli , Stefan Gerhard Holland-Cunz , Stephanie Gros , Martina Frech

Estimation of Protein-Ligand Unbinding Kinetics Using Non-Equilibrium Targeted Molecular Dynamics Simulations.

Journal of chemical information and modeling

Avec: Steffen Wolf , Marta Amaral , Maryse Lowinski , Francois Vallée , Djordje Musil , Jörn Güldenhaupt , Matthias K Dreyer , Jörg Bomke , Matthias Frech , Jürgen Schlitter , Klaus Gerwert

The Oncoprotein SKI Acts as A Suppressor of NK Cell-Mediated Immunosurveillance in PDAC.

Cancers

Avec: Viviane Ponath , Miriam Frech , Mathis Bittermann , Reem Al Khayer , Andreas Neubauer , Cornelia Brendel , Elke Pogge von Strandmann

Réseau de co-auteurs

Michael Frech 6 collaborations

Mario M Zaiss 6 collaborations

Kerstin Sarter 5 collaborations

Georg Schett 5 collaborations

Sébastien Lucas 4 collaborations

Kerstin Dürholz 4 collaborations

Stefan Wirtz 4 collaborations

Fabian Schälter 3 collaborations

Vugar Azizov 3 collaborations

Yasunori Omata 3 collaborations

Lisa Knipfer 3 collaborations

Narges Tajik 2 collaborations

Franziska Steffen 2 collaborations

Francesco Ciccia 2 collaborations

Madeleine Frech 2 collaborations

Marta Amaral 2 collaborations

Djordje Musil 2 collaborations

Oscar Schulz 1 collaboration

Andreas Rings 1 collaboration

Marko Bertog 1 collaboration

Aroldo Rizzo 1 collaboration

Aida Iljazovic 1 collaboration

Marijana Basic 1 collaboration

Arnd Kleyer 1 collaboration

Stephan Culemann 1 collaboration

Gerhard Krönke 1 collaboration

Yubin Luo 1 collaboration

Klaus Überla 1 collaboration

Udo S Gaipl 1 collaboration

Benjamin Frey 1 collaboration

Till Strowig 1 collaboration

Stephan C Bischoff 1 collaboration

Juan D Cañete 1 collaboration

Tatjana Primbs 1 collaboration

Yuho Kadono 1 collaboration

Taku Saito 1 collaboration

Sakae Tanaka 1 collaboration

Marie-Lena Frech 1 collaboration

Malte Friese 1 collaboration

David D Loschelder 1 collaboration

Luc Lebon 1 collaboration

Julia Esser-von Bieren 1 collaboration

Lalit K Dubey 1 collaboration

David Voehringer 1 collaboration

Nicola L Harris 1 collaboration

Tracy M Frech 1 collaboration

Inga Saknite 1 collaboration

Katie A O'Connell 1 collaboration

Shramana Ghosh 1 collaboration

Justin Baba 1 collaboration

Eric R Tkaczyk 1 collaboration

Alvaro Torres-Huerta 1 collaboration

Katelyn Ruley-Haase 1 collaboration

Theodore Reed 1 collaboration

Antonia Boger-May 1 collaboration

Derek Rubadeux 1 collaboration

Lauren Mayer 1 collaboration

Arpitha Mysore Rajashekara 1 collaboration

Morgan Hiller 1 collaboration

Connor Roncagli 1 collaboration

Cameron Pedersen 1 collaboration

Mary Catherine Camacho 1 collaboration

Lauren Hollmer 1 collaboration

Lauren English 1 collaboration

Grace Kane 1 collaboration

David L Boone 1 collaboration

Katharina Dietel 1 collaboration

Julia Meidenbauer 1 collaboration

Anne Kolenbrander 1 collaboration

Silvia Seubert 1 collaboration

Dennis Lapuente 1 collaboration

Maria V Sokolova 1 collaboration

Jörg Hofmann 1 collaboration

Matthias Tenbusch 1 collaboration

Andreas Ramming 1 collaboration

Ulrike Steffen 1 collaboration

Falk Nimmerjahn 1 collaboration

Ralf Linker 1 collaboration

Martin Herrmann 1 collaboration

Vladimir Temchura 1 collaboration

Benedict-Tilman Berger 1 collaboration

Daria B Kokh 1 collaboration

Ariane Nunes-Alves 1 collaboration

Timo Heinrich 1 collaboration

Martin Schröder 1 collaboration

Rebecca Neil 1 collaboration

Jing Wang 1 collaboration

Iva Navratilova 1 collaboration

Joerg Bomke 1 collaboration

Jonathan M Elkins 1 collaboration

Susanne Müller 1 collaboration

Rebecca C Wade 1 collaboration

Stefan Knapp 1 collaboration

Faustine Henot 1 collaboration

Rime Kerfah 1 collaboration

Ricarda Törner 1 collaboration

Pavel Macek 1 collaboration

Elodie Crublet 1 collaboration

Pierre Gans 1 collaboration

Olivier Hamelin 1 collaboration

Jerome Boisbouvier 1 collaboration

Heike Danzer 1 collaboration

Pooja Uchil 1 collaboration

Eva Schmid 1 collaboration

Daniele Mauro 1 collaboration

Simon Rauber 1 collaboration

Luis Muñoz 1 collaboration

Leila Taher 1 collaboration

Kilian Schober 1 collaboration

Magali Irla 1 collaboration

Vivienne Sommer-Jörgensen 1 collaboration

Markus Künzli 1 collaboration

Stefan Gerhard Holland-Cunz 1 collaboration

Stephanie Gros 1 collaboration

Martina Frech 1 collaboration

Steffen Wolf 1 collaboration

Maryse Lowinski 1 collaboration

Francois Vallée 1 collaboration

Jörn Güldenhaupt 1 collaboration

Matthias K Dreyer 1 collaboration

Jörg Bomke 1 collaboration

Jürgen Schlitter 1 collaboration

Klaus Gerwert 1 collaboration

Viviane Ponath 1 collaboration

Miriam Frech 1 collaboration

Mathis Bittermann 1 collaboration

Reem Al Khayer 1 collaboration

Andreas Neubauer 1 collaboration

Cornelia Brendel 1 collaboration

Elke Pogge von Strandmann 1 collaboration