Michael L Heien

Affiliations

Department of Chemistry and Biochemistry, BIO5, The University of Arizona, Tucson, AZ, United States.

Publications (22)

Design and Synthesis of Brain Penetrant Glycopeptide Analogues of PACAP With Neuroprotective Potential for Traumatic Brain Injury and Parkinsonism.

Frontiers in drug discovery

Avec: Christopher R Apostol , Kelsey Bernard , Parthasaradhireddy Tanguturi , Gabriella Molnar , Mitchell J Bartlett , Lajos Szabò , Chenxi Liu , J Bryce Ortiz , Maha Saber , Katherine R Giordano , Tabitha R F Green , James Melvin , Helena W Morrison , Lalitha Madhavan , Rachel K Rowe , John M Streicher , Michael L Heien , Torsten Falk , Robin Polt

Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion.

Brain research

Avec: Andrew J Flores , Mitchell J Bartlett , Blake T Seaton , Grace Samtani , Morgan R Sexauer , Nathan C Weintraub , James R Siegenthaler , Dong Lu , Michael L Heien , Frank Porreca , Scott J Sherman , Torsten Falk

Preclinical evidence in support of repurposing sub-anesthetic ketamine as a treatment for L-DOPA-induced dyskinesia.

Experimental neurology

Avec: Mitchell J Bartlett , Andrew J Flores , Tony Ye , Saskia I Smidt , Hannah K Dollish , Jennifer A Stancati , Drew C Farrell , Kate L Parent , Kristian P Doyle , David G Besselsen , Michael L Heien , Stephen L Cowen , Kathy Steece-Collier , Scott J Sherman , Torsten Falk

Sensitive and Selective Measurement of Serotonin

Analytical chemistry

Avec: Hojin Shin , Yoonbae Oh , Cheonho Park , Yumin Kang , Hyun U Cho , Charles D Blaha , Kevin E Bennet , Michael L Heien , In Young Kim , Kendall H Lee , Dong Pyo Jang

Neurochemical Concentration Prediction Using Deep Learning vs Principal Component Regression in Fast Scan Cyclic Voltammetry: A Comparison Study.

ACS chemical neuroscience

Avec: Hoseok Choi , Hojin Shin , Hyun U Cho , Charles D Blaha , Michael L Heien , Yoonbae Oh , Kendall H Lee , Dong Pyo Jang

Structure-Based Design of Glycosylated Oxytocin Analogues with Improved Selectivity and Antinociceptive Activity.

ACS medicinal chemistry letters

Avec: Lajos Z Szabó , Parthasaradhireddy Tanguturi , Hannah J Goodman , Sára Sprőber , Chenxi Liu , Fahad Al-Obeidi , Mitchell J Bartlett , Torsten Falk , Vlad K Kumirov , M Leandro Heien , John M Streicher , Robin Polt

Differential effects of opioid receptor antagonism on the anti-dyskinetic and anti-parkinsonian effects of sub-anesthetic ketamine treatment in a preclinical model.

Neuropharmacology

Avec: Carolyn J Stopera , Mitchell J Bartlett , Chenxi Liu , Alexander Esqueda , Raveena Parmar , M Leandro Heien , Scott J Sherman , Torsten Falk

A pain-induced tonic hypodopaminergic state augments phasic dopamine release in the nucleus accumbens.

Pain

Avec: Taylor A Gee , Nathan C Weintraub , Dong Lu , Caroline E Phelps , Edita Navratilova , Michael L Heien , Frank Porreca

A Novel Angiotensin-(1-7) Glycosylated Mas Receptor Agonist for Treating Vascular Cognitive Impairment and Inflammation-Related Memory Dysfunction.

The Journal of pharmacology and experimental therapeutics

Avec: Meredith Hay , Robin Polt , Michael L Heien , Todd W Vanderah , Tally M Largent-Milnes , Kathleen Rodgers , Torsten Falk , Mitchell J Bartlett , Kristian P Doyle , John P Konhilas

Techniques for Measurement of Serotonin: Implications in Neuropsychiatric Disorders and Advances in Absolute Value Recording Methods.

ACS chemical neuroscience

Avec: Juan M Rojas Cabrera , Tyler S Oesterle , Aaron E Rusheen , Abhinav Goyal , Kristen M Scheitler , Ian Mandybur , Charles D Blaha , Kevin E Bennet , Michael L Heien , Dong Pyo Jang , Kendall H Lee , Yoonbae Oh , Hojin Shin

Dopamine Release Dynamics in the Nucleus Accumbens Are Modulated by the Timing of Electrical Stimulation Pulses When Applied to the Medial Forebrain Bundle and Medial Prefrontal Cortex.

ACS chemical neuroscience

Avec: Andrea R Hamilton , Abhilasha Vishwanath , Nathan C Weintraub , Stephen L Cowen , M Leandro Heien

Tonic Serotonin Measurements

Analytical chemistry

Avec: Hojin Shin , Abhinav Goyal , J Hudson Barnett , Aaron E Rusheen , Jason Yuen , Rohan Jha , Sang Mun Hwang , Yumin Kang , Cheonho Park , Hyun-U Cho , Charles D Blaha , Kevin E Bennet , Yoonbae Oh , Michael L Heien , Dong Pyo Jang , Kendall H Lee

Moving Fast-Scan Cyclic Voltammetry toward FDA Compliance with Capacitive Decoupling Patient Protection.

ACS sensors

Avec: James R Siegenthaler , Breanna C Gushiken , Daniel F Hill , Stephen L Cowen , Michael L Heien

Biocompatible reference electrodes to enhance chronic electrochemical signal fidelity in vivo.

Analytical and bioanalytical chemistry

Avec: Blake T Seaton , Michael L Heien

Antagonism of kappa opioid receptors accelerates the development of L-DOPA-induced dyskinesia in a preclinical model of moderate dopamine depletion.

bioRxiv : the preprint server for biology

Understanding the different effects of fouling mechanisms on working and reference electrodes in fast-scan cyclic voltammetry for neurotransmitter detection.

The Analyst

Avec: Jaehyun Jang , Hyun-U Cho , Sangmun Hwang , Youngjong Kwak , Haeun Kwon , Michael L Heien , Kevin E Bennet , Yoonbae Oh , Hojin Shin , Kendall H Lee , Dong Pyo Jang

The angiotensin (1-7) glycopeptide PNA5 improvescognition in achronic progressive mouse model of Parkinson's disease through modulation of neuroinflammation.

Experimental neurology

Avec: Kelsey Bernard , Jesus A Mota , Paige Wene , Mandi J Corenblum , Juben L Saez , Mitchell J Bartlett , M Leandro Heien , Kristian P Doyle , Robin Polt , Meredith Hay , Lalitha Madhavan , Torsten Falk

Cyclic Glycopeptide Analogs of Endomorphin-1 Provide Highly Effective Antinociception in Male and Female Mice.

ACS medicinal chemistry letters

Avec: James E Zadina , Lajos Z Szabo , Fahad Al-Obeidi , Xing Zhang , Leticia Ferreira Nakatani , Chidiebere Ogbu , M Leandro Heien , Torsten Falk , Mitchell J Bartlett , Robin Polt

The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia.

International journal of molecular sciences

Avec: Mitchell J Bartlett , Omar S Mabrouk , Lajos Szabò , Andrew J Flores , Kate L Parent , Jean M Bidlack , Michael L Heien , Robert T Kennedy , Robin Polt , Scott J Sherman , Torsten Falk

Highly-selective µ-opioid receptor antagonism does not block L-DOPA-induced dyskinesia in a rodent model.

BMC research notes

Avec: Mitchell J Bartlett , Lisa Y So , Lajos Szabò , David P Skinner , Kate L Parent , Michael L Heien , Todd W Vanderah , Robin Polt , Scott J Sherman , Torsten Falk

Mitigating the Effects of Electrode Biofouling-Induced Impedance for Improved Long-Term Electrochemical Measurements In Vivo.

Analytical chemistry

Avec: Blake T Seaton , Daniel F Hill , Stephen L Cowen , Michael L Heien

Evaluation of electrochemical methods for tonic dopamine detection

Trends in analytical chemistry : TRAC

Avec: Aaron E Rusheen , Taylor A Gee , Dong P Jang , Charles D Blaha , Kevin E Bennet , Kendall H Lee , Michael L Heien , Yoonbae Oh

Réseau de co-auteurs

Mitchell J Bartlett 11 collaborations

Torsten Falk 11 collaborations

Robin Polt 7 collaborations

Scott J Sherman 6 collaborations

Yoonbae Oh 6 collaborations

Kendall H Lee 6 collaborations

Hojin Shin 5 collaborations

Charles D Blaha 5 collaborations

Kevin E Bennet 5 collaborations

Dong Pyo Jang 5 collaborations

M Leandro Heien 5 collaborations

Andrew J Flores 4 collaborations

Blake T Seaton 4 collaborations

Nathan C Weintraub 4 collaborations

Stephen L Cowen 4 collaborations

Lajos Szabò 3 collaborations

Chenxi Liu 3 collaborations

James R Siegenthaler 3 collaborations

Dong Lu 3 collaborations

Frank Porreca 3 collaborations

Kate L Parent 3 collaborations

Kristian P Doyle 3 collaborations

Aaron E Rusheen 3 collaborations

Kelsey Bernard 2 collaborations

Parthasaradhireddy Tanguturi 2 collaborations

Lalitha Madhavan 2 collaborations

John M Streicher 2 collaborations

Grace Samtani 2 collaborations

Morgan R Sexauer 2 collaborations

Cheonho Park 2 collaborations

Yumin Kang 2 collaborations

Hyun U Cho 2 collaborations

Fahad Al-Obeidi 2 collaborations

Taylor A Gee 2 collaborations

Meredith Hay 2 collaborations

Todd W Vanderah 2 collaborations

Abhinav Goyal 2 collaborations

Hyun-U Cho 2 collaborations

Daniel F Hill 2 collaborations

Christopher R Apostol 1 collaboration

Gabriella Molnar 1 collaboration

J Bryce Ortiz 1 collaboration

Maha Saber 1 collaboration

Katherine R Giordano 1 collaboration

Tabitha R F Green 1 collaboration

James Melvin 1 collaboration

Helena W Morrison 1 collaboration

Rachel K Rowe 1 collaboration

Tony Ye 1 collaboration

Saskia I Smidt 1 collaboration

Hannah K Dollish 1 collaboration

Jennifer A Stancati 1 collaboration

Drew C Farrell 1 collaboration

David G Besselsen 1 collaboration

Kathy Steece-Collier 1 collaboration

In Young Kim 1 collaboration

Hoseok Choi 1 collaboration

Lajos Z Szabó 1 collaboration

Hannah J Goodman 1 collaboration

Sára Sprőber 1 collaboration

Vlad K Kumirov 1 collaboration

Carolyn J Stopera 1 collaboration

Alexander Esqueda 1 collaboration

Raveena Parmar 1 collaboration

Caroline E Phelps 1 collaboration

Edita Navratilova 1 collaboration

Tally M Largent-Milnes 1 collaboration

Kathleen Rodgers 1 collaboration

John P Konhilas 1 collaboration

Juan M Rojas Cabrera 1 collaboration

Tyler S Oesterle 1 collaboration

Kristen M Scheitler 1 collaboration

Ian Mandybur 1 collaboration

Andrea R Hamilton 1 collaboration

Abhilasha Vishwanath 1 collaboration

J Hudson Barnett 1 collaboration

Jason Yuen 1 collaboration

Rohan Jha 1 collaboration

Sang Mun Hwang 1 collaboration

Breanna C Gushiken 1 collaboration

Jaehyun Jang 1 collaboration

Sangmun Hwang 1 collaboration

Youngjong Kwak 1 collaboration

Haeun Kwon 1 collaboration

Jesus A Mota 1 collaboration

Paige Wene 1 collaboration

Mandi J Corenblum 1 collaboration

Juben L Saez 1 collaboration

James E Zadina 1 collaboration

Lajos Z Szabo 1 collaboration

Xing Zhang 1 collaboration

Leticia Ferreira Nakatani 1 collaboration

Chidiebere Ogbu 1 collaboration

Omar S Mabrouk 1 collaboration

Jean M Bidlack 1 collaboration

Robert T Kennedy 1 collaboration

Lisa Y So 1 collaboration

David P Skinner 1 collaboration

Dong P Jang 1 collaboration