N Shire

Affiliations

AstraZeneca Pharmaceuticals, Gaithersburg, USA.

Publications (14)

PD-L1 expression, EGFR and KRAS mutations and survival among stage III unresected non-small cell lung cancer patients: a Danish cohort study.

Scientific reports

Avec: Deirdre Cronin-Fenton , Tapashi Dalvi , Naimisha Movva , Lars Pedersen , Hanh Hansen , Jon Fryzek , Elizabeth Hedgeman , Anders Mellemgaard , Torben R Rasmussen , Norah Shire , Stephen Hamilton-Dutoit , Mette Nørgaard

Design and Rationale for a Phase III, Randomized, Placebo-controlled Trial of Durvalumab With or Without Tremelimumab After Concurrent Chemoradiotherapy for Patients With Limited-stage Small-cell Lung Cancer: The ADRIATIC Study.

Clinical lung cancer

Avec: Suresh Senan , Isamu Okamoto , Gyeong-Won Lee , Yuanbin Chen , Seiji Niho , Gabriel Mak , Wenliang Yao , Norah Shire , Haiyi Jiang , Byoung Chul Cho

SUPREME-HN: a retrospective biomarker study assessing the prognostic value of PD-L1 expression in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck.

Journal of translational medicine

Avec: Sara I Pai , Ezra E W Cohen , Derrick Lin , George Fountzilas , Edward S Kim , Holger Mehlhorn , Neus Baste , Daniel Clayburgh , Loren Lipworth , Carlo Resteghini , Nawar Shara , Takashi Fujii , Jun Zhang , Michael Stokes , Huifen Wang , Philip Twumasi-Ankrah , Sophie Wildsmith , Asud Khaliq , Giovanni Melillo , Norah Shire

A Molecular Epidemiological Analysis Of Programmed Cell Death Ligand-1 (PD-L1) Protein Expression, Mutations And Survival In Non-Small Cell Lung Cancer.

Cancer management and research

Avec: Matthew B Schabath , Tapashi B Dalvi , Hongyue A Dai , Alan L Crim , Anita Midha , Norah Shire , Nicholas T Gimbrone , Jill Walker , Danielle M Greenawalt , David Lawrence , James R Rigas , Robert Brody , Danielle Potter , Naveen S Kumar , Shane A Huntsman , Jhanelle E Gray

Interferon gamma expression and mortality in unselected cohorts of urothelial bladder cancer patients.

PloS one

Avec: Christina Gillezeau , Naimisha Movva , Maaike van Gerwen , Karma Rabon-Stith , Norah Shire , Philip Zachary Brohawn , Emanuela Taioli , Jon Fryzek

NEPTUNE China cohort: First-line durvalumab plus tremelimumab in Chinese patients with metastatic non-small-cell lung cancer.

Lung cancer (Amsterdam, Netherlands)

Avec: Ying Cheng , Qing Zhou , Baohui Han , Yun Fan , Li Shan , Jianhua Chang , Si Sun , Jian Fang , Yuan Chen , Jianguo Sun , Gang Wu , Helen Mann , Kirsha Naicker , Norah Shire , Tony Mok , Gilberto de Castro

Efficacy and Safety of Trastuzumab Deruxtecan in Patients With HER2-Expressing Solid Tumors: Primary Results From the DESTINY-PanTumor02 Phase II Trial.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Funda Meric-Bernstam , Vicky Makker , Ana Oaknin , Do-Youn Oh , Susana Banerjee , Antonio González-Martín , Kyung Hae Jung , Iwona Ługowska , Luis Manso , Aránzazu Manzano , Bohuslav Melichar , Salvatore Siena , Daniil Stroyakovskiy , Anitra Fielding , Yan Ma , Soham Puvvada , Norah Shire , Jung-Yun Lee

Durvalumab plus platinum-etoposide versus platinum-etoposide in first-line treatment of extensive-stage small-cell lung cancer (CASPIAN): a randomised, controlled, open-label, phase 3 trial.

Lancet (London, England)

Avec: Luis Paz-Ares , Mikhail Dvorkin , Yuanbin Chen , Niels Reinmuth , Katsuyuki Hotta , Dmytro Trukhin , Galina Statsenko , Maximilian J Hochmair , Mustafa Özgüroğlu , Jun Ho Ji , Oleksandr Voitko , Artem Poltoratskiy , Santiago Ponce , Francesco Verderame , Libor Havel , Igor Bondarenko , Andrzej Kazarnowicz , György Losonczy , Nikolay V Conev , Jon Armstrong , Natalie Byrne , Norah Shire , Haiyi Jiang , Jonathan W Goldman , Auteur inconnu

HBV and HIV/HBV Infected Patients Have Distinct Immune Exhaustion and Apoptotic Serum Biomarker Profiles.

Pathogens & immunity

Avec: Mohamed Tarek M Shata , Enass A Abdel-Hameed , Susan D Rouster , Li Yu , Meina Liang , Esther Song , Mark T Esser , Norah Shire , Kenneth E Sherman

Association between immune-mediated adverse events and efficacy in metastatic non-small-cell lung cancer patients treated with durvalumab and tremelimumab.

Frontiers in immunology

Avec: Agnish Dey , Matthew Austin , Harriet M Kluger , Nataliya Trunova , Helen Mann , Norah Shire , Claire Morgan , Diansong Zhou , Ganesh M Mugundu

Patient-reported outcomes with first-line durvalumab plus platinum-etoposide versus platinum-etoposide in extensive-stage small-cell lung cancer (CASPIAN): a randomized, controlled, open-label, phase III study.

Lung cancer (Amsterdam, Netherlands)

Avec: Jonathan W Goldman , Marina Chiara Garassino , Yuanbin Chen , Mustafa Özgüroğlu , Mikhail Dvorkin , Dmytro Trukhin , Galina Statsenko , Katsuyuki Hotta , Jun Ho Ji , Maximilian J Hochmair , Oleksandr Voitko , Libor Havel , Artem Poltoratskiy , György Losonczy , Niels Reinmuth , Nikunj Patel , Peter J Laud , Norah Shire , Haiyi Jiang , Luis Paz-Ares

Programmed cell death ligand-1 expression and survival in a cohort of patients with non-small cell lung cancer receiving first-line through third-line therapy in Denmark.

Cancer epidemiology

Avec: Elizabeth Hedgeman , Mette Nørgaard , Tapashi Dalvi , Lars Pedersen , Hanh Pham Hansen , Jill Walker , Anita Midha , Norah Shire , Anne-Marie Boothman , Jon P Fryzek , James Rigas , Anders Mellemgaard , Torben R Rasmussen , Stephen Hamilton-Dutoit , Deirdre Cronin-Fenton

Pooled analysis of drug-related interstitial lung disease and/or pneumonitis in nine trastuzumab deruxtecan monotherapy studies.

ESMO open

Avec: C A Powell , S Modi , H Iwata , S Takahashi , E F Smit , S Siena , D-Y Chang , E Macpherson , A Qin , J Singh , C Taitt , N Shire , D Ross Camidge

Biomarker expression and survival in patients with non-small cell lung cancer receiving adjuvant chemotherapy in Denmark.

PloS one

Avec: Tapashi Dalvi , Mette Nørgaard , Jon P Fryzek , Naimisha Movva , Lars Pedersen , Hanh Pham Hansen , Jill Walker , Anita Midha , Norah Shire , Anne-Marie Boothman , James Rigas , Anders Mellemgaard , Torben R Rasmussen , Stephen Hamilton-Dutoit , Deirdre Cronin-Fenton

Réseau de co-auteurs

Norah Shire 13 collaborations

Deirdre Cronin-Fenton 3 collaborations

Tapashi Dalvi 3 collaborations

Naimisha Movva 3 collaborations

Lars Pedersen 3 collaborations

Anders Mellemgaard 3 collaborations

Torben R Rasmussen 3 collaborations

Stephen Hamilton-Dutoit 3 collaborations

Mette Nørgaard 3 collaborations

Yuanbin Chen 3 collaborations

Haiyi Jiang 3 collaborations

Anita Midha 3 collaborations

Jill Walker 3 collaborations

Jon Fryzek 2 collaborations

Elizabeth Hedgeman 2 collaborations

Helen Mann 2 collaborations

Luis Paz-Ares 2 collaborations

Mikhail Dvorkin 2 collaborations

Niels Reinmuth 2 collaborations

Katsuyuki Hotta 2 collaborations

Dmytro Trukhin 2 collaborations

Galina Statsenko 2 collaborations

Maximilian J Hochmair 2 collaborations

Mustafa Özgüroğlu 2 collaborations

Jun Ho Ji 2 collaborations

Oleksandr Voitko 2 collaborations

Artem Poltoratskiy 2 collaborations

Libor Havel 2 collaborations

György Losonczy 2 collaborations

Jonathan W Goldman 2 collaborations

Hanh Pham Hansen 2 collaborations

Anne-Marie Boothman 2 collaborations

Jon P Fryzek 2 collaborations

James Rigas 2 collaborations

Hanh Hansen 1 collaboration

Suresh Senan 1 collaboration

Isamu Okamoto 1 collaboration

Gyeong-Won Lee 1 collaboration

Seiji Niho 1 collaboration

Gabriel Mak 1 collaboration

Wenliang Yao 1 collaboration

Byoung Chul Cho 1 collaboration

Sara I Pai 1 collaboration

Ezra E W Cohen 1 collaboration

Derrick Lin 1 collaboration

George Fountzilas 1 collaboration

Edward S Kim 1 collaboration

Holger Mehlhorn 1 collaboration

Neus Baste 1 collaboration

Daniel Clayburgh 1 collaboration

Loren Lipworth 1 collaboration

Carlo Resteghini 1 collaboration

Nawar Shara 1 collaboration

Takashi Fujii 1 collaboration

Jun Zhang 1 collaboration

Michael Stokes 1 collaboration

Huifen Wang 1 collaboration

Philip Twumasi-Ankrah 1 collaboration

Sophie Wildsmith 1 collaboration

Asud Khaliq 1 collaboration

Giovanni Melillo 1 collaboration

Matthew B Schabath 1 collaboration

Tapashi B Dalvi 1 collaboration

Hongyue A Dai 1 collaboration

Alan L Crim 1 collaboration

Nicholas T Gimbrone 1 collaboration

Danielle M Greenawalt 1 collaboration

David Lawrence 1 collaboration

James R Rigas 1 collaboration

Robert Brody 1 collaboration

Danielle Potter 1 collaboration

Naveen S Kumar 1 collaboration

Shane A Huntsman 1 collaboration

Jhanelle E Gray 1 collaboration

Christina Gillezeau 1 collaboration

Maaike van Gerwen 1 collaboration

Karma Rabon-Stith 1 collaboration

Philip Zachary Brohawn 1 collaboration

Emanuela Taioli 1 collaboration

Ying Cheng 1 collaboration

Qing Zhou 1 collaboration

Baohui Han 1 collaboration

Yun Fan 1 collaboration

Li Shan 1 collaboration

Jianhua Chang 1 collaboration

Si Sun 1 collaboration

Jian Fang 1 collaboration

Yuan Chen 1 collaboration

Jianguo Sun 1 collaboration

Gang Wu 1 collaboration

Kirsha Naicker 1 collaboration

Tony Mok 1 collaboration

Gilberto de Castro 1 collaboration

Funda Meric-Bernstam 1 collaboration

Vicky Makker 1 collaboration

Ana Oaknin 1 collaboration

Do-Youn Oh 1 collaboration

Susana Banerjee 1 collaboration

Antonio González-Martín 1 collaboration

Kyung Hae Jung 1 collaboration

Iwona Ługowska 1 collaboration

Luis Manso 1 collaboration

Aránzazu Manzano 1 collaboration

Bohuslav Melichar 1 collaboration

Salvatore Siena 1 collaboration

Daniil Stroyakovskiy 1 collaboration

Anitra Fielding 1 collaboration

Yan Ma 1 collaboration

Soham Puvvada 1 collaboration

Jung-Yun Lee 1 collaboration

Santiago Ponce 1 collaboration

Francesco Verderame 1 collaboration

Igor Bondarenko 1 collaboration

Andrzej Kazarnowicz 1 collaboration

Nikolay V Conev 1 collaboration

Jon Armstrong 1 collaboration

Natalie Byrne 1 collaboration

None None 1 collaboration

Mohamed Tarek M Shata 1 collaboration

Enass A Abdel-Hameed 1 collaboration

Susan D Rouster 1 collaboration

Li Yu 1 collaboration

Meina Liang 1 collaboration

Esther Song 1 collaboration

Mark T Esser 1 collaboration

Kenneth E Sherman 1 collaboration

Agnish Dey 1 collaboration

Matthew Austin 1 collaboration

Harriet M Kluger 1 collaboration

Nataliya Trunova 1 collaboration

Claire Morgan 1 collaboration

Diansong Zhou 1 collaboration

Ganesh M Mugundu 1 collaboration

Marina Chiara Garassino 1 collaboration

Nikunj Patel 1 collaboration

Peter J Laud 1 collaboration

C A Powell 1 collaboration

S Modi 1 collaboration

H Iwata 1 collaboration

S Takahashi 1 collaboration

E F Smit 1 collaboration

S Siena 1 collaboration

D-Y Chang 1 collaboration

E Macpherson 1 collaboration

A Qin 1 collaboration

J Singh 1 collaboration

C Taitt 1 collaboration

D Ross Camidge 1 collaboration