Nehal E Elsadek

Affiliations

Department of Pharmacokinetics and Biopharmaceutics, Institute of Biomedical Sciences, Tokushima University, 1-78-1 Sho-machi, Tokushima, Japan.

Publications (11)

Hepatosplenic phagocytic cells indirectly contribute to anti-PEG IgM production in the accelerated blood clearance (ABC) phenomenon against PEGylated liposomes: Appearance of an unexplained mechanism in the ABC phenomenon.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Marwa Mohamed El Sayed , Haruka Takata , Taro Shimizu , Yoshino Kawaguchi , Amr S Abu Lila , Nehal E Elsadek , Eman Alaaeldin , Yu Ishima , Hidenori Ando , Amal Kamal , Hatem A Sarhan , Tatsuhiro Ishida

Incorporating Gangliosides into PEGylated Cationic Liposomes that Complexed DNA Attenuates Anti-PEG Antibody Production but Not Anti-DNA Antibody Production in Mice.

Molecular pharmaceutics

Avec: Milad Reda Qelliny , Taro Shimizu , Nehal E Elsadek , Sherif E Emam , Haruka Takata , Zeinab M A Fathalla , Amal K Hussein , Khaled A Khaled , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Impact of Pre-Existing or Induced Anti-PEG IgM on the Pharmacokinetics of Peginterferon Alfa-2a (Pegasys) in Mice.

Molecular pharmaceutics

Avec: Nehal E Elsadek , Eri Hondo , Taro Shimizu , Haruka Takata , Amr S Abu Lila , Sherif E Emam , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Pegfilgrastim (PEG-G-CSF) Induces Anti-polyethylene Glycol (PEG) IgM via a T Cell-Dependent Mechanism.

Biological & pharmaceutical bulletin

Avec: Nehal E Elsadek , Sherif E Emam , Amr S Abu Lila , Taro Shimizu , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Polyethylene glycol (PEG): The nature, immunogenicity, and role in the hypersensitivity of PEGylated products.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Mohamed Ibrahim , Eslam Ramadan , Nehal E Elsadek , Sherif E Emam , Taro Shimizu , Hidenori Ando , Yu Ishima , Omar Helmy Elgarhy , Hatem A Sarhan , Amal K Hussein , Tatsuhiro Ishida

Cancer cell-type tropism is one of crucial determinants for the efficient systemic delivery of cancer cell-derived exosomes to tumor tissues.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Sherif E Emam , Amr Selim Abu Lila , Nehal E Elsadek , Hidenori Ando , Taro Shimizu , Keiichiro Okuhira , Yu Ishima , Mahmoud A Mahdy , Fakhr-Eldin S Ghazy , Tatsuhiro Ishida

Anti-PEG IgM production and accelerated blood clearance phenomenon after the administration of PEGylated exosomes in mice.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Sherif E Emam , Nehal E Elsadek , Amr S Abu Lila , Haruka Takata , Yoshino Kawaguchi , Taro Shimizu , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Electrospun Nanofibers Revisited: An Update on the Emerging Applications in Nanomedicine.

Materials (Basel, Switzerland)

Avec: Nehal E Elsadek , Abdalrazeq Nagah , Tarek M Ibrahim , Hitesh Chopra , Ghada A Ghonaim , Sherif E Emam , Simona Cavalu , Mohamed S Attia

A mouse model for studying the effect of blood anti-PEG IgMs levels on the in vivo fate of PEGylated liposomes.

International journal of pharmaceutics

Avec: Marwa M El Sayed , Taro Shimizu , Amr S Abu Lila , Nehal E Elsadek , Sherif E Emam , Eman Alaaeldin , Amal Kamal , Hatem A Sarhan , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Anti-PEG IgM production induced by PEGylated liposomes as a function of administration route.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Haruka Takata , Taro Shimizu , Rina Yamade , Nehal E Elsadek , Sherif E Emam , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Pegfilgrastim (PEG-G-CSF) induces anti-PEG IgM in a dose dependent manner and causes the accelerated blood clearance (ABC) phenomenon upon repeated administration in mice.

European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V

Avec: Nehal E Elsadek , Amr S Abu Lila , Sherif E Emam , Taro Shimizu , Haruka Takata , Hidenori Ando , Yu Ishima , Tatsuhiro Ishida

Réseau de co-auteurs

Taro Shimizu 10 collaborations

Yu Ishima 10 collaborations

Hidenori Ando 10 collaborations

Tatsuhiro Ishida 10 collaborations

Sherif E Emam 10 collaborations

Haruka Takata 6 collaborations

Amr S Abu Lila 6 collaborations

Hatem A Sarhan 3 collaborations

Yoshino Kawaguchi 2 collaborations

Eman Alaaeldin 2 collaborations

Amal Kamal 2 collaborations

Amal K Hussein 2 collaborations

Marwa Mohamed El Sayed 1 collaboration

Milad Reda Qelliny 1 collaboration

Zeinab M A Fathalla 1 collaboration

Khaled A Khaled 1 collaboration

Eri Hondo 1 collaboration

Mohamed Ibrahim 1 collaboration

Eslam Ramadan 1 collaboration

Omar Helmy Elgarhy 1 collaboration

Amr Selim Abu Lila 1 collaboration

Keiichiro Okuhira 1 collaboration

Mahmoud A Mahdy 1 collaboration

Fakhr-Eldin S Ghazy 1 collaboration

Abdalrazeq Nagah 1 collaboration

Tarek M Ibrahim 1 collaboration

Hitesh Chopra 1 collaboration

Ghada A Ghonaim 1 collaboration

Simona Cavalu 1 collaboration

Mohamed S Attia 1 collaboration

Marwa M El Sayed 1 collaboration

Rina Yamade 1 collaboration