Patrick Mollat

Affiliations

Galapagos SASU, 102 Avenue Gaston Roussel, 93230 Romainville, France.

Publications (5)

Pharmacological characterization of GLPG1972/S201086, a potent and selective small-molecule inhibitor of ADAMTS5.

Osteoarthritis and cartilage

Avec: P Clement-Lacroix , C B Little , M M Smith , C Cottereaux , D Merciris , S Meurisse , P Mollat , R Touitou , F Brebion , R Gosmini , F De Ceuninck , I Botez , L Lepescheux , E van der Aar , T Christophe , N Vandervoort , R Blanqué , D Comas , P Deprez , D Amantini

Discovery of GLPG1972/S201086, a Potent, Selective, and Orally Bioavailable ADAMTS-5 Inhibitor for the Treatment of Osteoarthritis.

Journal of medicinal chemistry

Avec: Franck Brebion , Romain Gosmini , Pierre Deprez , Marie Varin , Christophe Peixoto , Luke Alvey , Hélène Jary , Natacha Bienvenu , Nicolas Triballeau , Roland Blanque , Céline Cottereaux , Thierry Christophe , Nele Vandervoort , Patrick Mollat , Robert Touitou , Philip Leonard , Frédéric De Ceuninck , Iuliana Botez , Alain Monjardet , Ellen van der Aar , David Amantini

Combined administration of a small-molecule inhibitor of TRAF6 and Docetaxel reduces breast cancer skeletal metastasis and osteolysis.

Cancer letters

Avec: Ryan T Bishop , Silvia Marino , Giovana Carrasco , Boya Li , Richard J Allen , Anna Sparatore , Penelope D Ottewell , Patrick Mollat , Andrew H Sims , Mattia Capulli , Ning Wang , Aymen I Idris

Anti-inflammatory, but not osteoprotective, effect of the TRAF6/CD40 inhibitor 6877002 in rodent models of local and systemic osteolysis.

Biochemical pharmacology

Avec: Silvia Marino , Nicole Hannemann , Ryan T Bishop , Feier Zeng , Giovana Carrasco , Sandrine Meurisse , Boya Li , Antonia Sophocleous , Anna Sparatore , Tobias Baeuerle , Slobodan Vukicevic , Marielle Auberval , Patrick Mollat , Aline Bozec , Aymen I Idris

Optimization of Selectivity and Pharmacokinetic Properties of Salt-Inducible Kinase Inhibitors that Led to the Discovery of Pan-SIK Inhibitor GLPG3312.

Journal of medicinal chemistry

Avec: Taouès Temal-Laib , Christophe Peixoto , Nicolas Desroy , Elsa De Lemos , Florence Bonnaterre , Natacha Bienvenu , Olivier Picolet , Eric Sartori , Denis Bucher , Miriam López-Ramos , Carlos Roca Magadán , Wendy Laenen , Thomas Flower , Patrick Mollat , Olivier Bugaud , Robert Touitou , Anna Pereira Fernandes , Stephanie Lavazais , Alain Monjardet , Monica Borgonovi , Romain Gosmini , Reginald Brys , David Amantini , Steve De Vos , Martin Andrews

Réseau de co-auteurs

Romain Gosmini 2 collaborations

Christophe Peixoto 2 collaborations

Natacha Bienvenu 2 collaborations

Robert Touitou 2 collaborations

Alain Monjardet 2 collaborations

David Amantini 2 collaborations

Ryan T Bishop 2 collaborations

Silvia Marino 2 collaborations

Giovana Carrasco 2 collaborations

Boya Li 2 collaborations

Anna Sparatore 2 collaborations

Aymen I Idris 2 collaborations

P Clement-Lacroix 1 collaboration

C B Little 1 collaboration

M M Smith 1 collaboration

C Cottereaux 1 collaboration

D Merciris 1 collaboration

S Meurisse 1 collaboration

P Mollat 1 collaboration

R Touitou 1 collaboration

F Brebion 1 collaboration

R Gosmini 1 collaboration

F De Ceuninck 1 collaboration

I Botez 1 collaboration

L Lepescheux 1 collaboration

E van der Aar 1 collaboration

T Christophe 1 collaboration

N Vandervoort 1 collaboration

R Blanqué 1 collaboration

D Comas 1 collaboration

P Deprez 1 collaboration

D Amantini 1 collaboration

Franck Brebion 1 collaboration

Pierre Deprez 1 collaboration

Marie Varin 1 collaboration

Luke Alvey 1 collaboration

Hélène Jary 1 collaboration

Nicolas Triballeau 1 collaboration

Roland Blanque 1 collaboration

Céline Cottereaux 1 collaboration

Thierry Christophe 1 collaboration

Nele Vandervoort 1 collaboration

Philip Leonard 1 collaboration

Frédéric De Ceuninck 1 collaboration

Iuliana Botez 1 collaboration

Ellen van der Aar 1 collaboration

Richard J Allen 1 collaboration

Penelope D Ottewell 1 collaboration

Andrew H Sims 1 collaboration

Mattia Capulli 1 collaboration

Ning Wang 1 collaboration

Nicole Hannemann 1 collaboration

Feier Zeng 1 collaboration

Sandrine Meurisse 1 collaboration

Antonia Sophocleous 1 collaboration

Tobias Baeuerle 1 collaboration

Slobodan Vukicevic 1 collaboration

Marielle Auberval 1 collaboration

Aline Bozec 1 collaboration

Taouès Temal-Laib 1 collaboration

Nicolas Desroy 1 collaboration

Elsa De Lemos 1 collaboration

Florence Bonnaterre 1 collaboration

Olivier Picolet 1 collaboration

Eric Sartori 1 collaboration

Denis Bucher 1 collaboration

Miriam López-Ramos 1 collaboration

Carlos Roca Magadán 1 collaboration

Wendy Laenen 1 collaboration

Thomas Flower 1 collaboration

Olivier Bugaud 1 collaboration

Anna Pereira Fernandes 1 collaboration

Stephanie Lavazais 1 collaboration

Monica Borgonovi 1 collaboration

Reginald Brys 1 collaboration

Steve De Vos 1 collaboration

Martin Andrews 1 collaboration