Paul D Kassner

Affiliations

RAPT Therapeutics, 561 Eccles Avenue, South San Francisco, California 94080, United States.

Publications (8)

Novel Piperidinyl-Azetidines as Potent and Selective CCR4 Antagonists Elicit Antitumor Response as a Single Agent and in Combination with Checkpoint Inhibitors.

Journal of medicinal chemistry

Avec: Omar Robles , Jeffrey J Jackson , Lisa Marshall , Oezcan Talay , David Chian , Gene Cutler , Raymond Diokno , Dennis X Hu , Scott Jacobson , Emily Karbarz , Paul D Kassner , John M Ketcham , Jenny McKinnell , Cesar Meleza , Maureen K Reilly , Erin Riegler , Hunter P Shunatona , Angela Wadsworth , Ashkaan Younai , Dirk G Brockstedt , David J Wustrow , Mikhail Zibinsky

Novel, Selective Inhibitors of USP7 Uncover Multiple Mechanisms of Antitumor Activity

Molecular cancer therapeutics

Avec: Yamini M Ohol , Michael T Sun , Gene Cutler , Paul R Leger , Dennis X Hu , Berenger Biannic , Payal Rana , Cynthia Cho , Scott Jacobson , Steve T Wong , Jerick Sanchez , Niket Shah , Deepa Pookot , Betty Abraham , Kyle Young , Silpa Suthram , Lisa A Marshall , Delia Bradford , Nathan Kozon , Xinping Han , Akinori Okano , Jack Maung , Christophe Colas , Jacob Schwarz , David Wustrow , Dirk G Brockstedt , Paul D Kassner

EBV+ tumors exploit tumor cell-intrinsic and -extrinsic mechanisms to produce regulatory T cell-recruiting chemokines CCL17 and CCL22.

PLoS pathogens

Avec: Aparna Jorapur , Lisa A Marshall , Scott Jacobson , Mengshu Xu , Sachie Marubayashi , Mikhail Zibinsky , Dennis X Hu , Omar Robles , Jeffrey J Jackson , Valentin Baloche , Pierre Busson , David Wustrow , Dirk G Brockstedt , Oezcan Talay , Paul D Kassner , Gene Cutler

Clinical and molecular effects of oral CCR4 antagonist RPT193 in atopic dermatitis: A Phase 1 study.

Allergy

Avec: Robert Bissonnette , Janet DuBois , Paola Facheris , Ester Del Duca , Madeline Kim , Joel Correa Da Rosa , Damian L Trujillo , Swaroop Bose , Angel D Pagan , David Wustrow , Dirk G Brockstedt , Brian Wong , Paul D Kassner , Jasmina Jankicevic , William Ho , Laurence E Cheng , Emma Guttman-Yassky

Discovery of Potent, Selective, and Orally Bioavailable Inhibitors of USP7 with In Vivo Antitumor Activity.

Journal of medicinal chemistry

Avec: Paul R Leger , Dennis X Hu , Berenger Biannic , Minna Bui , Xinping Han , Emily Karbarz , Jack Maung , Akinori Okano , Maksim Osipov , Grant M Shibuya , Kyle Young , Christopher Higgs , Betty Abraham , Delia Bradford , Cynthia Cho , Christophe Colas , Scott Jacobson , Yamini M Ohol , Deepa Pookot , Payal Rana , Jerick Sanchez , Niket Shah , Michael Sun , Steve Wong , Dirk G Brockstedt , Paul D Kassner , Jacob B Schwarz , David J Wustrow

Potent GCN2 Inhibitor Capable of Reversing MDSC-Driven T Cell Suppression Demonstrates In Vivo Efficacy as a Single Agent and in Combination with Anti-Angiogenesis Therapy.

Journal of medicinal chemistry

Avec: Jeffrey J Jackson , Grant M Shibuya , Buvana Ravishankar , Lavanya Adusumilli , Delia Bradford , Dirk G Brockstedt , Cyril Bucher , Minna Bui , Cynthia Cho , Christoph Colas , Gene Cutler , Adrian Dukes , Xinping Han , Dennis X Hu , Scott Jacobson , Paul D Kassner , George E Katibah , Michelle Yoo Min Ko , Urvi Kolhatkar , Paul R Leger , Anqi Ma , Lisa Marshall , Jack Maung , Andrew A Ng , Akinori Okano , Deepa Pookot , Daniel Poon , Chandru Ramana , Maureen K Reilly , Omar Robles , Jacob B Schwarz , Anton A Shakhmin , Hunter P Shunatona , Raashi Sreenivasan , Parcharee Tivitmahaisoon , Mengshu Xu , Thant Zaw , David J Wustrow , Mikhail Zibinsky

Tumors establish resistance to immunotherapy by regulating T

Journal for immunotherapy of cancer

Avec: Lisa A Marshall , Sachie Marubayashi , Aparna Jorapur , Scott Jacobson , Mikhail Zibinsky , Omar Robles , Dennis Xiaozhou Hu , Jeffrey J Jackson , Deepa Pookot , Jerick Sanchez , Martin Brovarney , Angela Wadsworth , David Chian , David Wustrow , Paul D Kassner , Gene Cutler , Brian Wong , Dirk G Brockstedt , Oezcan Talay

Discovery of a Potent and Selective CCR4 Antagonist That Inhibits T

Journal of medicinal chemistry

Avec: Jeffrey J Jackson , John M Ketcham , Ashkaan Younai , Betty Abraham , Berenger Biannic , Hilary P Beck , Minna H T Bui , David Chian , Gene Cutler , Raymond Diokno , Dennis X Hu , Scott Jacobson , Emily Karbarz , Paul D Kassner , Lisa Marshall , Jenny McKinnell , Cesar Meleza , Abood Okal , Deepa Pookot , Maureen K Reilly , Omar Robles , Hunter P Shunatona , Oezcan Talay , James R Walker , Angela Wadsworth , David J Wustrow , Mikhail Zibinsky

Réseau de co-auteurs

Scott Jacobson 7 collaborations

Dirk G Brockstedt 7 collaborations

Gene Cutler 6 collaborations

Dennis X Hu 6 collaborations

Omar Robles 5 collaborations

Jeffrey J Jackson 5 collaborations

Mikhail Zibinsky 5 collaborations

Deepa Pookot 5 collaborations

Oezcan Talay 4 collaborations

David J Wustrow 4 collaborations

David Wustrow 4 collaborations

Lisa Marshall 3 collaborations

David Chian 3 collaborations

Emily Karbarz 3 collaborations

Maureen K Reilly 3 collaborations

Hunter P Shunatona 3 collaborations

Angela Wadsworth 3 collaborations

Paul R Leger 3 collaborations

Berenger Biannic 3 collaborations

Cynthia Cho 3 collaborations

Jerick Sanchez 3 collaborations

Betty Abraham 3 collaborations

Lisa A Marshall 3 collaborations

Delia Bradford 3 collaborations

Xinping Han 3 collaborations

Akinori Okano 3 collaborations

Jack Maung 3 collaborations

Raymond Diokno 2 collaborations

John M Ketcham 2 collaborations

Jenny McKinnell 2 collaborations

Cesar Meleza 2 collaborations

Ashkaan Younai 2 collaborations

Yamini M Ohol 2 collaborations

Payal Rana 2 collaborations

Niket Shah 2 collaborations

Kyle Young 2 collaborations

Christophe Colas 2 collaborations

Aparna Jorapur 2 collaborations

Mengshu Xu 2 collaborations

Sachie Marubayashi 2 collaborations

Brian Wong 2 collaborations

Minna Bui 2 collaborations

Grant M Shibuya 2 collaborations

Jacob B Schwarz 2 collaborations

Erin Riegler 1 collaboration

Michael T Sun 1 collaboration

Steve T Wong 1 collaboration

Silpa Suthram 1 collaboration

Nathan Kozon 1 collaboration

Jacob Schwarz 1 collaboration

Valentin Baloche 1 collaboration

Pierre Busson 1 collaboration

Robert Bissonnette 1 collaboration

Janet DuBois 1 collaboration

Paola Facheris 1 collaboration

Ester Del Duca 1 collaboration

Madeline Kim 1 collaboration

Joel Correa Da Rosa 1 collaboration

Damian L Trujillo 1 collaboration

Swaroop Bose 1 collaboration

Angel D Pagan 1 collaboration

Jasmina Jankicevic 1 collaboration

William Ho 1 collaboration

Laurence E Cheng 1 collaboration

Emma Guttman-Yassky 1 collaboration

Maksim Osipov 1 collaboration

Christopher Higgs 1 collaboration

Michael Sun 1 collaboration

Steve Wong 1 collaboration

Buvana Ravishankar 1 collaboration

Lavanya Adusumilli 1 collaboration

Cyril Bucher 1 collaboration

Christoph Colas 1 collaboration

Adrian Dukes 1 collaboration

George E Katibah 1 collaboration

Michelle Yoo Min Ko 1 collaboration

Urvi Kolhatkar 1 collaboration

Anqi Ma 1 collaboration

Andrew A Ng 1 collaboration

Daniel Poon 1 collaboration

Chandru Ramana 1 collaboration

Anton A Shakhmin 1 collaboration

Raashi Sreenivasan 1 collaboration

Parcharee Tivitmahaisoon 1 collaboration

Thant Zaw 1 collaboration

Dennis Xiaozhou Hu 1 collaboration

Martin Brovarney 1 collaboration

Hilary P Beck 1 collaboration

Minna H T Bui 1 collaboration

Abood Okal 1 collaboration

James R Walker 1 collaboration