Petr Chlapek

Affiliations

Department of Experimental Biology, Faculty of Science, Masaryk University, 61137 Brno, Czech Republic.
International Clinical Research Center, St. Anne's University Hospital, 65691 Brno, Czech Republic.

ORCID: 0000-0002-7274-897X

Publications (9)

Thiosemicarbazones Can Act Synergistically with Anthracyclines to Downregulate CHEK1 Expression and Induce DNA Damage in Cell Lines Derived from Pediatric Solid Tumors.

International journal of molecular sciences

Avec: Silvia Paukovcekova , Maria Krchniakova , Petr Chlapek , Jakub Neradil , Jan Skoda , Renata Veselska

Novel Thiosemicarbazones Sensitize Pediatric Solid Tumor Cell-Types to Conventional Chemotherapeutics through Multiple Molecular Mechanisms.

Cancers

Avec: Silvia Paukovcekova , Jan Skoda , Jakub Neradil , Erika Mikulenkova , Petr Chlapek , Jaroslav Sterba , Des R Richardson , Renata Veselska

Serotonin limits generation of chromaffin cells during adrenal organ development.

Nature communications

Avec: Polina Kameneva , Victoria I Melnikova , Maria Eleni Kastriti , Anastasia Kurtova , Emil Kryukov , Aliia Murtazina , Louis Faure , Irina Poverennaya , Artem V Artemov , Tatiana S Kalinina , Nikita V Kudryashov , Michael Bader , Jan Skoda , Petr Chlapek , Lucie Curylova , Lukas Sourada , Jakub Neradil , Marketa Tesarova , Massimo Pasqualetti , Patricia Gaspar , Vasily D Yakushov , Boris I Sheftel , Tomas Zikmund , Jozef Kaiser , Kaj Fried , Natalia Alenina , Elena E Voronezhskaya , Igor Adameyko

Comparative Analysis of Putative Prognostic and Predictive Markers in Neuroblastomas: High Expression of PBX1 Is Associated With a Poor Response to Induction Therapy.

Frontiers in oncology

Avec: Renata Veselska , Marta Jezova , Michal Kyr , Pavel Mazanek , Petr Chlapek , Viera Dobrotkova , Jaroslav Sterba

Repurposing Tyrosine Kinase Inhibitors to Overcome Multidrug Resistance in Cancer: A Focus on Transporters and Lysosomal Sequestration.

International journal of molecular sciences

Avec: Maria Krchniakova , Jan Skoda , Jakub Neradil , Petr Chlapek , Renata Veselska

New inhibitor of the TAp73 interaction with MDM2 and mutant p53 with promising antitumor activity against neuroblastoma.

Cancer letters

Avec: Sara Gomes , Liliana Raimundo , Joana Soares , Joana B Loureiro , Mariana Leão , Helena Ramos , Madalena N Monteiro , Agostinho Lemos , Joana Moreira , Madalena Pinto , Petr Chlapek , Renata Veselska , Emília Sousa , Lucília Saraiva

Prediction of neuroblastoma cell response to treatment with natural or synthetic retinoids using selected protein biomarkers.

PloS one

Avec: Viera Dobrotkova , Petr Chlapek , Marta Jezova , Katerina Adamkova , Pavel Mazanek , Jaroslav Sterba , Renata Veselska

A selective p53 activator and anticancer agent to improve colorectal cancer therapy.

Cell reports

Avec: Helena Ramos , Maria I L Soares , Joana Silva , Liliana Raimundo , Juliana Calheiros , Célia Gomes , Flávio Reis , Filipe A Monteiro , Cláudia Nunes , Salette Reis , Bartolomeo Bosco , Silvano Piazza , Lucília Domingues , Petr Chlapek , Petr Vlcek , Pavel Fabian , Ana Teresa Rajado , A T P Carvalho , Renata Veselska , Alberto Inga , Teresa M V D Pinho E Melo , Lucília Saraiva

Thiosemicarbazones and selected tyrosine kinase inhibitors synergize in pediatric solid tumors: NDRG1 upregulation and impaired prosurvival signaling in neuroblastoma cells.

Frontiers in pharmacology

Avec: Maria Krchniakova , Silvia Paukovcekova , Petr Chlapek , Jakub Neradil , Jan Skoda , Renata Veselska

Réseau de co-auteurs

Renata Veselska 8 collaborations

Jakub Neradil 5 collaborations

Jan Skoda 5 collaborations

Silvia Paukovcekova 3 collaborations

Maria Krchniakova 3 collaborations

Jaroslav Sterba 3 collaborations

Marta Jezova 2 collaborations

Pavel Mazanek 2 collaborations

Viera Dobrotkova 2 collaborations

Liliana Raimundo 2 collaborations

Helena Ramos 2 collaborations

Lucília Saraiva 2 collaborations

Erika Mikulenkova 1 collaboration

Des R Richardson 1 collaboration

Polina Kameneva 1 collaboration

Victoria I Melnikova 1 collaboration

Maria Eleni Kastriti 1 collaboration

Anastasia Kurtova 1 collaboration

Emil Kryukov 1 collaboration

Aliia Murtazina 1 collaboration

Louis Faure 1 collaboration

Irina Poverennaya 1 collaboration

Artem V Artemov 1 collaboration

Tatiana S Kalinina 1 collaboration

Nikita V Kudryashov 1 collaboration

Michael Bader 1 collaboration

Lucie Curylova 1 collaboration

Lukas Sourada 1 collaboration

Marketa Tesarova 1 collaboration

Massimo Pasqualetti 1 collaboration

Patricia Gaspar 1 collaboration

Vasily D Yakushov 1 collaboration

Boris I Sheftel 1 collaboration

Tomas Zikmund 1 collaboration

Jozef Kaiser 1 collaboration

Kaj Fried 1 collaboration

Natalia Alenina 1 collaboration

Elena E Voronezhskaya 1 collaboration

Igor Adameyko 1 collaboration

Michal Kyr 1 collaboration

Sara Gomes 1 collaboration

Joana Soares 1 collaboration

Joana B Loureiro 1 collaboration

Mariana Leão 1 collaboration

Madalena N Monteiro 1 collaboration

Agostinho Lemos 1 collaboration

Joana Moreira 1 collaboration

Madalena Pinto 1 collaboration

Emília Sousa 1 collaboration

Katerina Adamkova 1 collaboration

Maria I L Soares 1 collaboration

Joana Silva 1 collaboration

Juliana Calheiros 1 collaboration

Célia Gomes 1 collaboration

Flávio Reis 1 collaboration

Filipe A Monteiro 1 collaboration

Cláudia Nunes 1 collaboration

Salette Reis 1 collaboration

Bartolomeo Bosco 1 collaboration

Silvano Piazza 1 collaboration

Lucília Domingues 1 collaboration

Petr Vlcek 1 collaboration

Pavel Fabian 1 collaboration

Ana Teresa Rajado 1 collaboration

A T P Carvalho 1 collaboration

Alberto Inga 1 collaboration

Teresa M V D Pinho E Melo 1 collaboration