Philippe Lechat

Affiliations

Paris-cité University, Paris, France. philippe.lechat@aphp.fr.
Pharmacology and Toxicology Department, Georges Pompidou European Hospital, Drug Evaluation unit, Agence Générale des équipements et des produits de santé (AGEPS), 7 rue du fer à moulin, 75005 Paris, Assistance Publique des Hôpitaux de Paris, France. philippe.lechat@aphp.fr.

Publications (15)

Multitrait GWAS to connect disease variants and biological mechanisms.

PLoS genetics

Avec: Hanna Julienne , Vincent Laville , Zachary R McCaw , Zihuai He , Vincent Guillemot , Carla Lasry , Andrey Ziyatdinov , Cyril Nerin , Amaury Vaysse , Pierre Lechat , Hervé Ménager , Wilfried Le Goff , Marie-Pierre Dube , Peter Kraft , Iuliana Ionita-Laza , Bjarni J Vilhjálmsson , Hugues Aschard

Within-subject pharmacokinetic variability has a strong influence on individual exposure ratios in bioequivalence studies, hence on drug formulation interchangeability.

European journal of clinical pharmacology

Avec: Philippe Lechat , Fatma Kir , Pierre Marquet , Jean-Baptiste Woillard

Trait selection strategy in multi-trait GWAS: Boosting SNPs discoverability.

bioRxiv : the preprint server for biology

Avec: Yuka Suzuki , Hervé Ménager , Bryan Brancotte , Raphaël Vernet , Cyril Nerin , Christophe Boetto , Antoine Auvergne , Christophe Linhard , Rachel Torchet , Pierre Lechat , Lucie Troubat , Michael H Cho , Emmanuelle Bouzigon , Hugues Aschard , Hanna Julienne

JASS: command line and web interface for the joint analysis of GWAS results.

NAR genomics and bioinformatics

Avec: Hanna Julienne , Pierre Lechat , Vincent Guillemot , Carla Lasry , Chunzi Yao , Robinson Araud , Vincent Laville , Bjarni Vilhjalmsson , Hervé Ménager , Hugues Aschard

Interchangeability between Generic and Reference Products: Limits of Average Bioequivalence Methodology.

European journal of drug metabolism and pharmacokinetics

Avec: Philippe Lechat

Comparing methods for constructing and representing human pangenome graphs.

Genome biology

Avec: Francesco Andreace , Pierre Lechat , Yoann Dufresne , Rayan Chikhi

How can the environmental sustainability of healthcare products be taken into account throughout their life cycle?

Therapie

Avec: Bruno Laviolle , Pierre-Frédéric Degon , Cécile Gillet-Giraud , Dominique Thiveaud , Philippe Lechat , Vera Boïko-Alaux , Claire Fougerou , Clara Jolly , Abir Petit , Isabelle Rémy-Jouet , Raphaël Yven , Laurence Bouret , Laurie Marrauld , Marie-Pierre Vaslet , Virginie Delay , Anne-Laure Gavory , Florence Olle , Julie Langevin , Louise Forteau

Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen.

bioRxiv : the preprint server for biology

Avec: Samuel G Huete , Alejandro Leyva , Etienne Kornobis , Thomas Cokelaer , Pierre Lechat , Marc Monot , Rosario Duran , Mathieu Picardeau , Nadia Benaroudj

SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis.

BMC bioinformatics

Avec: Stevenn Volant , Pierre Lechat , Perrine Woringer , Laurence Motreff , Pascal Campagne , Christophe Malabat , Sean Kennedy , Amine Ghozlane

The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.

PLoS pathogens

Avec: Crispin Zavala-Alvarado , Samuel G Huete , Antony T Vincent , Odile Sismeiro , Rachel Legendre , Hugo Varet , Giovanni Bussotti , Céline Lorioux , Pierre Lechat , Jean-Yves Coppée , Frédéric J Veyrier , Mathieu Picardeau , Nadia Benaroudj

Trait selection strategy in multi-trait GWAS: Boosting SNPs discoverability.

HGG advances

Avec: Yuka Suzuki , Hervé Ménager , Bryan Brancotte , Raphaël Vernet , Cyril Nerin , Christophe Boetto , Antoine Auvergne , Christophe Linhard , Rachel Torchet , Pierre Lechat , Lucie Troubat , Michael H Cho , Emmanuelle Bouzigon , Hugues Aschard , Hanna Julienne

[Biosimilar medicines: Regulatory issues and medico-economic impacts].

Bulletin de l'Academie nationale de medecine

Avec: P Lechat

Climate change and vector-borne diseases: a multi-omics approach of temperature-induced changes in the mosquito.

Journal of travel medicine

Avec: Rachel Bellone , Pierre Lechat , Laurence Mousson , Valentine Gilbart , Géraldine Piorkowski , Chloé Bohers , Andres Merits , Etienne Kornobis , Julie Reveillaud , Christophe Paupy , Marie Vazeille , Jean-Philippe Martinet , Yoann Madec , Xavier De Lamballerie , Catherine Dauga , Anna-Bella Failloux

Health research and innovation: Can we optimize the interface between startups/pharmaceutical companies and academic health care institutions or not?

Therapie

Avec: Jean-François Dhainaut , Olivier Blin , Florence Herry , Auteur inconnu , Sylvain Benito , Pascal Bilbault , Maxime Cauterman , Florence Favrel-Feuillade , Stéphanie Fazi-Leblanc , Caroline Germain , Clément Goehrs , Cécile Grosskopf , Benoit Labarthe , Philippe Lechat , Corneliu Malciu , Pierre Marquet , Corinne Miceli-Richard , Olivier Peyret , Revital Rattenbach , Edouard de Saint-Exupéry

Yersiniomics, a Multi-Omics Interactive Database for

Microbiology spectrum

Avec: Pierre Lê-Bury , Karen Druart , Cyril Savin , Pierre Lechat , Guillem Mas Fiol , Mariette Matondo , Christophe Bécavin , Olivier Dussurget , Javier Pizarro-Cerdá

Réseau de co-auteurs

Pierre Lechat 10 collaborations

Hanna Julienne 4 collaborations

Hervé Ménager 4 collaborations

Hugues Aschard 4 collaborations

Cyril Nerin 3 collaborations

Vincent Laville 2 collaborations

Vincent Guillemot 2 collaborations

Carla Lasry 2 collaborations

Pierre Marquet 2 collaborations

Yuka Suzuki 2 collaborations

Bryan Brancotte 2 collaborations

Raphaël Vernet 2 collaborations

Christophe Boetto 2 collaborations

Antoine Auvergne 2 collaborations

Christophe Linhard 2 collaborations

Rachel Torchet 2 collaborations

Lucie Troubat 2 collaborations

Michael H Cho 2 collaborations

Emmanuelle Bouzigon 2 collaborations

Samuel G Huete 2 collaborations

Etienne Kornobis 2 collaborations

Mathieu Picardeau 2 collaborations

Nadia Benaroudj 2 collaborations

Zachary R McCaw 1 collaboration

Zihuai He 1 collaboration

Andrey Ziyatdinov 1 collaboration

Amaury Vaysse 1 collaboration

Wilfried Le Goff 1 collaboration

Marie-Pierre Dube 1 collaboration

Peter Kraft 1 collaboration

Iuliana Ionita-Laza 1 collaboration

Bjarni J Vilhjálmsson 1 collaboration

Fatma Kir 1 collaboration

Jean-Baptiste Woillard 1 collaboration

Chunzi Yao 1 collaboration

Robinson Araud 1 collaboration

Bjarni Vilhjalmsson 1 collaboration

Francesco Andreace 1 collaboration

Yoann Dufresne 1 collaboration

Rayan Chikhi 1 collaboration

Bruno Laviolle 1 collaboration

Pierre-Frédéric Degon 1 collaboration

Cécile Gillet-Giraud 1 collaboration

Dominique Thiveaud 1 collaboration

Vera Boïko-Alaux 1 collaboration

Claire Fougerou 1 collaboration

Clara Jolly 1 collaboration

Abir Petit 1 collaboration

Isabelle Rémy-Jouet 1 collaboration

Raphaël Yven 1 collaboration

Laurence Bouret 1 collaboration

Laurie Marrauld 1 collaboration

Marie-Pierre Vaslet 1 collaboration

Virginie Delay 1 collaboration

Anne-Laure Gavory 1 collaboration

Florence Olle 1 collaboration

Julie Langevin 1 collaboration

Louise Forteau 1 collaboration

Alejandro Leyva 1 collaboration

Thomas Cokelaer 1 collaboration

Marc Monot 1 collaboration

Rosario Duran 1 collaboration

Stevenn Volant 1 collaboration

Perrine Woringer 1 collaboration

Laurence Motreff 1 collaboration

Pascal Campagne 1 collaboration

Christophe Malabat 1 collaboration

Sean Kennedy 1 collaboration

Amine Ghozlane 1 collaboration

Crispin Zavala-Alvarado 1 collaboration

Antony T Vincent 1 collaboration

Odile Sismeiro 1 collaboration

Rachel Legendre 1 collaboration

Hugo Varet 1 collaboration

Giovanni Bussotti 1 collaboration

Céline Lorioux 1 collaboration

Jean-Yves Coppée 1 collaboration

Frédéric J Veyrier 1 collaboration

P Lechat 1 collaboration

Rachel Bellone 1 collaboration

Laurence Mousson 1 collaboration

Valentine Gilbart 1 collaboration

Géraldine Piorkowski 1 collaboration

Chloé Bohers 1 collaboration

Andres Merits 1 collaboration

Julie Reveillaud 1 collaboration

Christophe Paupy 1 collaboration

Marie Vazeille 1 collaboration

Jean-Philippe Martinet 1 collaboration

Yoann Madec 1 collaboration

Xavier De Lamballerie 1 collaboration

Catherine Dauga 1 collaboration

Anna-Bella Failloux 1 collaboration

Jean-François Dhainaut 1 collaboration

Olivier Blin 1 collaboration

Florence Herry 1 collaboration

None None 1 collaboration

Sylvain Benito 1 collaboration

Pascal Bilbault 1 collaboration

Maxime Cauterman 1 collaboration

Florence Favrel-Feuillade 1 collaboration

Stéphanie Fazi-Leblanc 1 collaboration

Caroline Germain 1 collaboration

Clément Goehrs 1 collaboration

Cécile Grosskopf 1 collaboration

Benoit Labarthe 1 collaboration

Corneliu Malciu 1 collaboration

Corinne Miceli-Richard 1 collaboration

Olivier Peyret 1 collaboration

Revital Rattenbach 1 collaboration

Edouard de Saint-Exupéry 1 collaboration

Pierre Lê-Bury 1 collaboration

Karen Druart 1 collaboration

Cyril Savin 1 collaboration

Guillem Mas Fiol 1 collaboration

Mariette Matondo 1 collaboration

Christophe Bécavin 1 collaboration

Olivier Dussurget 1 collaboration

Javier Pizarro-Cerdá 1 collaboration