Pierre Vanderhaeghen

Affiliations

Université Libre de Bruxelles (U.L.B.), Institut de Recherches en Biologie Humaine et Moléculaire (IRIBHM), and ULB Neuroscience Institute (UNI), 1070 Brussels, Belgium; VIB-KULeuven Center for Brain & Disease Research, KULeuven Department of Neurosciences, Leuven Brain Institute, 3000 Leuven, Belgium. Electronic address: pierre.vanderhaeghen@kuleuven.vib.be.

Publications (22)

Neuronal fate acquisition and specification: time for a change.

Current opinion in neurobiology

Avec: Jérôme Bonnefont , Pierre Vanderhaeghen

Mitochondria metabolism sets the species-specific tempo of neuronal development.

Science (New York, N.Y.)

Avec: Ryohei Iwata , Pierre Casimir , Emir Erkol , Leïla Boubakar , Mélanie Planque , Isabel M Gallego López , Martyna Ditkowska , Vaiva Gaspariunaite , Sofie Beckers , Daan Remans , Katlijn Vints , Anke Vandekeere , Suresh Poovathingal , Matthew Bird , Ine Vlaeminck , Eline Creemers , Keimpe Wierda , Nikky Corthout , Pieter Vermeersch , Sébastien Carpentier , Kristofer Davie , Massimiliano Mazzone , Natalia V Gounko , Stein Aerts , Bart Ghesquière , Sarah-Maria Fendt , Pierre Vanderhaeghen

Studying human neural function in vivo at the cellular level: Chasing chimeras?

Cell

Avec: Ben Vermaercke , Vincent Bonin , Pierre Vanderhaeghen

Synaptic neoteny of human cortical neurons requires species-specific balancing of SRGAP2-SYNGAP1 cross-inhibition.

Neuron

Avec: Baptiste Libé-Philippot , Ryohei Iwata , Aleksandra J Recupero , Keimpe Wierda , Sergio Bernal Garcia , Luke Hammond , Anja van Benthem , Ridha Limame , Martyna Ditkowska , Sofie Beckers , Vaiva Gaspariunaite , Eugénie Peze-Heidsieck , Daan Remans , Cécile Charrier , Tom Theys , Franck Polleux , Pierre Vanderhaeghen

Cellular and Molecular Mechanisms Linking Human Cortical Development and Evolution.

Annual review of genetics

Avec: Baptiste Libé-Philippot , Pierre Vanderhaeghen

Xenotransplanted Human Cortical Neurons Reveal Species-Specific Development and Functional Integration into Mouse Visual Circuits.

Neuron

Avec: Daniele Linaro , Ben Vermaercke , Ryohei Iwata , Arjun Ramaswamy , Baptiste Libé-Philippot , Leila Boubakar , Brittany A Davis , Keimpe Wierda , Kristofer Davie , Suresh Poovathingal , Pier-Andrée Penttila , Angéline Bilheu , Lore De Bruyne , David Gall , Karl-Klaus Conzelmann , Vincent Bonin , Pierre Vanderhaeghen

Developmental mechanisms underlying the evolution of human cortical circuits.

Nature reviews. Neuroscience

Avec: Pierre Vanderhaeghen , Franck Polleux

SYNGAP1 deficiency disrupts synaptic neoteny in xenotransplanted human cortical neurons in vivo.

Neuron

Avec: Ben Vermaercke , Ryohei Iwata , Keimpe Wierda , Leïla Boubakar , Paula Rodriguez , Martyna Ditkowska , Vincent Bonin , Pierre Vanderhaeghen

Protocol to process fresh human cerebral cortex biopsies for patch-clamp recording and immunostaining.

STAR protocols

Avec: Keimpe Wierda , Hajnalka Nyitrai , Amélie Lejeune , Ine Vlaeminck , Elke Leysen , Tom Theys , Joris de Wit , Pierre Vanderhaeghen , Baptiste Libé-Philippot

CTNND2 moderates the pace of synaptic maturation and links human evolution to synaptic neoteny.

Cell reports

Avec: Nora Assendorp , Matteo Fossati , Baptiste Libé-Philippot , Eirini Christopoulou , Marine Depp , Roberta Rapone , Florent Dingli , Damarys Loew , Pierre Vanderhaeghen , Cécile Charrier

Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways.

Neuron

Avec: Jerome Bonnefont , Luca Tiberi , Jelle van den Ameele , Delphine Potier , Zachary B Gaber , Xionghui Lin , Angéline Bilheu , Adèle Herpoel , Fausto D Velez Bravo , François Guillemot , Stein Aerts , Pierre Vanderhaeghen

Mitochondrial dynamics in postmitotic cells regulate neurogenesis.

Science (New York, N.Y.)

Avec: Ryohei Iwata , Pierre Casimir , Pierre Vanderhaeghen

Regulatory roles of mitochondria and metabolism in neurogenesis.

Current opinion in neurobiology

Avec: Ryohei Iwata , Pierre Vanderhaeghen

Linking mitochondria metabolism, developmental timing, and human brain evolution.

Current opinion in genetics & development

Avec: Pierre Casimir , Ryohei Iwata , Pierre Vanderhaeghen

If you please, draw me a neuron - linking evolutionary tinkering with human neuron evolution.

Current opinion in genetics & development

Avec: Baptiste Libé-Philippot , Franck Polleux , Pierre Vanderhaeghen

1q21.1 distal copy number variants are associated with cerebral and cognitive alterations in humans.

Translational psychiatry

Avec: Ida E Sønderby , Dennis van der Meer , Clara Moreau , Tobias Kaufmann , G Bragi Walters , Maria Ellegaard , Abdel Abdellaoui , David Ames , Katrin Amunts , Micael Andersson , Nicola J Armstrong , Manon Bernard , Nicholas B Blackburn , John Blangero , Dorret I Boomsma , Henry Brodaty , Rachel M Brouwer , Robin Bülow , Rune Bøen , Wiepke Cahn , Vince D Calhoun , Svenja Caspers , Christopher R K Ching , Sven Cichon , Simone Ciufolini , Benedicto Crespo-Facorro , Joanne E Curran , Anders M Dale , Shareefa Dalvie , Paola Dazzan , Eco J C de Geus , Greig I de Zubicaray , Sonja M C de Zwarte , Sylvane Desrivieres , Joanne L Doherty , Gary Donohoe , Bogdan Draganski , Stefan Ehrlich , Else Eising , Thomas Espeseth , Kim Fejgin , Simon E Fisher , Tormod Fladby , Oleksandr Frei , Vincent Frouin , Masaki Fukunaga , Thomas Gareau , Tian Ge , David C Glahn , Hans J Grabe , Nynke A Groenewold , Ómar Gústafsson , Jan Haavik , Asta K Haberg , Jeremy Hall , Ryota Hashimoto , Jayne Y Hehir-Kwa , Derrek P Hibar , Manon H J Hillegers , Per Hoffmann , Laurena Holleran , Avram J Holmes , Georg Homuth , Jouke-Jan Hottenga , Hilleke E Hulshoff Pol , Masashi Ikeda , Neda Jahanshad , Christiane Jockwitz , Stefan Johansson , Erik G Jönsson , Niklas R Jørgensen , Masataka Kikuchi , Emma E M Knowles , Kuldeep Kumar , Stephanie Le Hellard , Costin Leu , David E J Linden , Jingyu Liu , Arvid Lundervold , Astri Johansen Lundervold , Anne M Maillard , Nicholas G Martin , Sandra Martin-Brevet , Karen A Mather , Samuel R Mathias , Katie L McMahon , Allan F McRae , Sarah E Medland , Andreas Meyer-Lindenberg , Torgeir Moberget , Claudia Modenato , Jennifer Monereo Sánchez , Derek W Morris , Thomas W Mühleisen , Robin M Murray , Jacob Nielsen , Jan E Nordvik , Lars Nyberg , Loes M Olde Loohuis , Roel A Ophoff , Michael J Owen , Tomas Paus , Zdenka Pausova , Juan M Peralta , G Bruce Pike , Carlos Prieto , Erin B Quinlan , Céline S Reinbold , Tiago Reis Marques , James J H Rucker , Perminder S Sachdev , Sigrid B Sando , Peter R Schofield , Andrew J Schork , Gunter Schumann , Jean Shin , Elena Shumskaya , Ana I Silva , Sanjay M Sisodiya , Vidar M Steen , Dan J Stein , Lachlan T Strike , Ikuo K Suzuki , Christian K Tamnes , Alexander Teumer , Anbupalam Thalamuthu , Diana Tordesillas-Gutiérrez , Anne Uhlmann , Magnus O Ulfarsson , Dennis van 't Ent , Marianne B M van den Bree , Pierre Vanderhaeghen , Evangelos Vassos , Wei Wen , Katharina Wittfeld , Margaret J Wright , Ingrid Agartz , Srdjan Djurovic , Lars T Westlye , Hreinn Stefansson , Kari Stefansson , Sébastien Jacquemont , Paul M Thompson , Ole A Andreassen , Auteur inconnu

YIPF5 mutations cause neonatal diabetes and microcephaly through endoplasmic reticulum stress.

The Journal of clinical investigation

Avec: Elisa De Franco , Maria Lytrivi , Hazem Ibrahim , Hossam Montaser , Matthew N Wakeling , Federica Fantuzzi , Kashyap Patel , Céline Demarez , Ying Cai , Mariana Igoillo-Esteve , Cristina Cosentino , Väinö Lithovius , Helena Vihinen , Eija Jokitalo , Thomas W Laver , Matthew B Johnson , Toshiaki Sawatani , Hadis Shakeri , Nathalie Pachera , Belma Haliloglu , Mehmet Nuri Ozbek , Edip Unal , Ruken Yıldırım , Tushar Godbole , Melek Yildiz , Banu Aydin , Angeline Bilheu , Ikuo Suzuki , Sarah E Flanagan , Pierre Vanderhaeghen , Valérie Senée , Cécile Julier , Piero Marchetti , Decio L Eizirik , Sian Ellard , Jonna Saarimäki-Vire , Timo Otonkoski , Miriam Cnop , Andrew T Hattersley

CROCCP2 acts as a human-specific modifier of cilia dynamics and mTOR signaling to promote expansion of cortical progenitors.

Neuron

Avec: Roxane Van Heurck , Jérôme Bonnefont , Marta Wojno , Ikuo K Suzuki , Fausto D Velez-Bravo , Emir Erkol , Dan Truc Nguyen , Adèle Herpoel , Angéline Bilheu , Sofie Beckers , Catherine Ledent , Pierre Vanderhaeghen

Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development.

Neuron

Avec: Louis-Jan Pilaz , Jing Liu , Kaumudi Joshi , Yuji Tsunekawa , Camila M Musso , Brooke R D'Arcy , Ikuo K Suzuki , Fernando C Alsina , Pratiksha Kc , Sahil Sethi , Pierre Vanderhaeghen , Franck Polleux , Debra L Silver

Repetitive CREB-DNA interactions at gene loci predetermined by CBP induce activity-dependent gene expression in human cortical neurons.

Cell reports

Avec: Yuri Atsumi , Ryohei Iwata , Hiroshi Kimura , Pierre Vanderhaeghen , Nobuhiko Yamamoto , Noriyuki Sugo

LRRC37B is a human modifier of voltage-gated sodium channels and axon excitability in cortical neurons.

Cell

Avec: Baptiste Libé-Philippot , Amélie Lejeune , Keimpe Wierda , Nikolaos Louros , Emir Erkol , Ine Vlaeminck , Sofie Beckers , Vaiva Gaspariunaite , Angéline Bilheu , Katerina Konstantoulea , Hajnalka Nyitrai , Matthias De Vleeschouwer , Kristel M Vennekens , Niels Vidal , Thomas W Bird , Daniela C Soto , Tom Jaspers , Maarten Dewilde , Megan Y Dennis , Frederic Rousseau , Davide Comoletti , Joost Schymkowitz , Tom Theys , Joris de Wit , Pierre Vanderhaeghen

Metabolic mechanisms of species-specific developmental tempo.

Developmental cell

Avec: Ryohei Iwata , Pierre Vanderhaeghen

Réseau de co-auteurs

Ryohei Iwata 9 collaborations

Baptiste Libé-Philippot 7 collaborations

Keimpe Wierda 6 collaborations

Sofie Beckers 4 collaborations

Franck Polleux 4 collaborations

Angéline Bilheu 4 collaborations

Pierre Casimir 3 collaborations

Emir Erkol 3 collaborations

Martyna Ditkowska 3 collaborations

Vaiva Gaspariunaite 3 collaborations

Ine Vlaeminck 3 collaborations

Ben Vermaercke 3 collaborations

Vincent Bonin 3 collaborations

Tom Theys 3 collaborations

Ikuo K Suzuki 3 collaborations

Jérôme Bonnefont 2 collaborations

Leïla Boubakar 2 collaborations

Daan Remans 2 collaborations

Suresh Poovathingal 2 collaborations

Kristofer Davie 2 collaborations

Stein Aerts 2 collaborations

Cécile Charrier 2 collaborations

Hajnalka Nyitrai 2 collaborations

Amélie Lejeune 2 collaborations

Joris de Wit 2 collaborations

Adèle Herpoel 2 collaborations

Mélanie Planque 1 collaboration

Isabel M Gallego López 1 collaboration

Katlijn Vints 1 collaboration

Anke Vandekeere 1 collaboration

Matthew Bird 1 collaboration

Eline Creemers 1 collaboration

Nikky Corthout 1 collaboration

Pieter Vermeersch 1 collaboration

Sébastien Carpentier 1 collaboration

Massimiliano Mazzone 1 collaboration

Natalia V Gounko 1 collaboration

Bart Ghesquière 1 collaboration

Sarah-Maria Fendt 1 collaboration

Aleksandra J Recupero 1 collaboration

Sergio Bernal Garcia 1 collaboration

Luke Hammond 1 collaboration

Anja van Benthem 1 collaboration

Ridha Limame 1 collaboration

Eugénie Peze-Heidsieck 1 collaboration

Daniele Linaro 1 collaboration

Arjun Ramaswamy 1 collaboration

Leila Boubakar 1 collaboration

Brittany A Davis 1 collaboration

Pier-Andrée Penttila 1 collaboration

Lore De Bruyne 1 collaboration

David Gall 1 collaboration

Karl-Klaus Conzelmann 1 collaboration

Paula Rodriguez 1 collaboration

Elke Leysen 1 collaboration

Nora Assendorp 1 collaboration

Matteo Fossati 1 collaboration

Eirini Christopoulou 1 collaboration

Marine Depp 1 collaboration

Roberta Rapone 1 collaboration

Florent Dingli 1 collaboration

Damarys Loew 1 collaboration

Jerome Bonnefont 1 collaboration

Luca Tiberi 1 collaboration

Jelle van den Ameele 1 collaboration

Delphine Potier 1 collaboration

Zachary B Gaber 1 collaboration

Xionghui Lin 1 collaboration

Fausto D Velez Bravo 1 collaboration

François Guillemot 1 collaboration

Ida E Sønderby 1 collaboration

Dennis van der Meer 1 collaboration

Clara Moreau 1 collaboration

Tobias Kaufmann 1 collaboration

G Bragi Walters 1 collaboration

Maria Ellegaard 1 collaboration

Abdel Abdellaoui 1 collaboration

David Ames 1 collaboration

Katrin Amunts 1 collaboration

Micael Andersson 1 collaboration

Nicola J Armstrong 1 collaboration

Manon Bernard 1 collaboration

Nicholas B Blackburn 1 collaboration

John Blangero 1 collaboration

Dorret I Boomsma 1 collaboration

Henry Brodaty 1 collaboration

Rachel M Brouwer 1 collaboration

Robin Bülow 1 collaboration

Rune Bøen 1 collaboration

Wiepke Cahn 1 collaboration

Vince D Calhoun 1 collaboration

Svenja Caspers 1 collaboration

Christopher R K Ching 1 collaboration

Sven Cichon 1 collaboration

Simone Ciufolini 1 collaboration

Benedicto Crespo-Facorro 1 collaboration

Joanne E Curran 1 collaboration

Anders M Dale 1 collaboration

Shareefa Dalvie 1 collaboration

Paola Dazzan 1 collaboration

Eco J C de Geus 1 collaboration

Greig I de Zubicaray 1 collaboration

Sonja M C de Zwarte 1 collaboration

Sylvane Desrivieres 1 collaboration

Joanne L Doherty 1 collaboration

Gary Donohoe 1 collaboration

Bogdan Draganski 1 collaboration

Stefan Ehrlich 1 collaboration

Else Eising 1 collaboration

Thomas Espeseth 1 collaboration

Kim Fejgin 1 collaboration

Simon E Fisher 1 collaboration

Tormod Fladby 1 collaboration

Oleksandr Frei 1 collaboration

Vincent Frouin 1 collaboration

Masaki Fukunaga 1 collaboration

Thomas Gareau 1 collaboration

Tian Ge 1 collaboration

David C Glahn 1 collaboration

Hans J Grabe 1 collaboration

Nynke A Groenewold 1 collaboration

Ómar Gústafsson 1 collaboration

Jan Haavik 1 collaboration

Asta K Haberg 1 collaboration

Jeremy Hall 1 collaboration

Ryota Hashimoto 1 collaboration

Jayne Y Hehir-Kwa 1 collaboration

Derrek P Hibar 1 collaboration

Manon H J Hillegers 1 collaboration

Per Hoffmann 1 collaboration

Laurena Holleran 1 collaboration

Avram J Holmes 1 collaboration

Georg Homuth 1 collaboration

Jouke-Jan Hottenga 1 collaboration

Hilleke E Hulshoff Pol 1 collaboration

Masashi Ikeda 1 collaboration

Neda Jahanshad 1 collaboration

Christiane Jockwitz 1 collaboration

Stefan Johansson 1 collaboration

Erik G Jönsson 1 collaboration

Niklas R Jørgensen 1 collaboration

Masataka Kikuchi 1 collaboration

Emma E M Knowles 1 collaboration

Kuldeep Kumar 1 collaboration

Stephanie Le Hellard 1 collaboration

Costin Leu 1 collaboration

David E J Linden 1 collaboration

Jingyu Liu 1 collaboration

Arvid Lundervold 1 collaboration

Astri Johansen Lundervold 1 collaboration

Anne M Maillard 1 collaboration

Nicholas G Martin 1 collaboration

Sandra Martin-Brevet 1 collaboration

Karen A Mather 1 collaboration

Samuel R Mathias 1 collaboration

Katie L McMahon 1 collaboration

Allan F McRae 1 collaboration

Sarah E Medland 1 collaboration

Andreas Meyer-Lindenberg 1 collaboration

Torgeir Moberget 1 collaboration

Claudia Modenato 1 collaboration

Jennifer Monereo Sánchez 1 collaboration

Derek W Morris 1 collaboration

Thomas W Mühleisen 1 collaboration

Robin M Murray 1 collaboration

Jacob Nielsen 1 collaboration

Jan E Nordvik 1 collaboration

Lars Nyberg 1 collaboration

Loes M Olde Loohuis 1 collaboration

Roel A Ophoff 1 collaboration

Michael J Owen 1 collaboration

Tomas Paus 1 collaboration

Zdenka Pausova 1 collaboration

Juan M Peralta 1 collaboration

G Bruce Pike 1 collaboration

Carlos Prieto 1 collaboration

Erin B Quinlan 1 collaboration

Céline S Reinbold 1 collaboration

Tiago Reis Marques 1 collaboration

James J H Rucker 1 collaboration

Perminder S Sachdev 1 collaboration

Sigrid B Sando 1 collaboration

Peter R Schofield 1 collaboration

Andrew J Schork 1 collaboration

Gunter Schumann 1 collaboration

Jean Shin 1 collaboration

Elena Shumskaya 1 collaboration

Ana I Silva 1 collaboration

Sanjay M Sisodiya 1 collaboration

Vidar M Steen 1 collaboration

Dan J Stein 1 collaboration

Lachlan T Strike 1 collaboration

Christian K Tamnes 1 collaboration

Alexander Teumer 1 collaboration

Anbupalam Thalamuthu 1 collaboration

Diana Tordesillas-Gutiérrez 1 collaboration

Anne Uhlmann 1 collaboration

Magnus O Ulfarsson 1 collaboration

Dennis van 't Ent 1 collaboration

Marianne B M van den Bree 1 collaboration

Evangelos Vassos 1 collaboration

Wei Wen 1 collaboration

Katharina Wittfeld 1 collaboration

Margaret J Wright 1 collaboration

Ingrid Agartz 1 collaboration

Srdjan Djurovic 1 collaboration

Lars T Westlye 1 collaboration

Hreinn Stefansson 1 collaboration

Kari Stefansson 1 collaboration

Sébastien Jacquemont 1 collaboration

Paul M Thompson 1 collaboration

Ole A Andreassen 1 collaboration

None None 1 collaboration

Elisa De Franco 1 collaboration

Maria Lytrivi 1 collaboration

Hazem Ibrahim 1 collaboration

Hossam Montaser 1 collaboration

Matthew N Wakeling 1 collaboration

Federica Fantuzzi 1 collaboration

Kashyap Patel 1 collaboration

Céline Demarez 1 collaboration

Ying Cai 1 collaboration

Mariana Igoillo-Esteve 1 collaboration

Cristina Cosentino 1 collaboration

Väinö Lithovius 1 collaboration

Helena Vihinen 1 collaboration

Eija Jokitalo 1 collaboration

Thomas W Laver 1 collaboration

Matthew B Johnson 1 collaboration

Toshiaki Sawatani 1 collaboration

Hadis Shakeri 1 collaboration

Nathalie Pachera 1 collaboration

Belma Haliloglu 1 collaboration

Mehmet Nuri Ozbek 1 collaboration

Edip Unal 1 collaboration

Ruken Yıldırım 1 collaboration

Tushar Godbole 1 collaboration

Melek Yildiz 1 collaboration

Banu Aydin 1 collaboration

Angeline Bilheu 1 collaboration

Ikuo Suzuki 1 collaboration

Sarah E Flanagan 1 collaboration

Valérie Senée 1 collaboration

Cécile Julier 1 collaboration

Piero Marchetti 1 collaboration

Decio L Eizirik 1 collaboration

Sian Ellard 1 collaboration

Jonna Saarimäki-Vire 1 collaboration

Timo Otonkoski 1 collaboration

Miriam Cnop 1 collaboration

Andrew T Hattersley 1 collaboration

Roxane Van Heurck 1 collaboration

Marta Wojno 1 collaboration

Fausto D Velez-Bravo 1 collaboration

Dan Truc Nguyen 1 collaboration

Catherine Ledent 1 collaboration

Louis-Jan Pilaz 1 collaboration

Jing Liu 1 collaboration

Kaumudi Joshi 1 collaboration

Yuji Tsunekawa 1 collaboration

Camila M Musso 1 collaboration

Brooke R D'Arcy 1 collaboration

Fernando C Alsina 1 collaboration

Pratiksha Kc 1 collaboration

Sahil Sethi 1 collaboration

Debra L Silver 1 collaboration

Yuri Atsumi 1 collaboration

Hiroshi Kimura 1 collaboration

Nobuhiko Yamamoto 1 collaboration

Noriyuki Sugo 1 collaboration

Nikolaos Louros 1 collaboration

Katerina Konstantoulea 1 collaboration

Matthias De Vleeschouwer 1 collaboration

Kristel M Vennekens 1 collaboration

Niels Vidal 1 collaboration

Thomas W Bird 1 collaboration

Daniela C Soto 1 collaboration

Tom Jaspers 1 collaboration

Maarten Dewilde 1 collaboration

Megan Y Dennis 1 collaboration

Frederic Rousseau 1 collaboration

Davide Comoletti 1 collaboration

Joost Schymkowitz 1 collaboration