Prakash Saudagar

Affiliations

Department of Biotechnology, National Institute of Technology-Warangal, Warangal, Telangana, 506004, India. ps@nitw.ac.in.

ORCID: http://orcid.org/0000-0001-7211-0581

Publications (37)

An overview of biochemically characterized drug targets in metabolic pathways of Leishmania parasite.

Parasitology research

Avec: Shweta Raj , Santanu Sasidharan , S N Balaji , Prakash Saudagar

Biofunctionalized Chrysin-conjugated gold nanoparticles neutralize Leishmania parasites with high efficacy.

International journal of biological macromolecules

Avec: Shweta Raj , Santanu Sasidharan , Timir Tripathi , Prakash Saudagar

In vitro and in vivo evaluation of probiotic potential and safety assessment of Bacillus coagulans SKB LAB-19 (MCC 0554) in humans and animal healthcare.

Regulatory toxicology and pharmacology : RTP

Avec: Khushal Chaudhari , Mahalaxmi Mohan , Parag Saudagar , Chetna Sable , Sominath Shinde , Dattatray Bedade

Design of SaCas9-HF for In Vivo Gene Therapy.

Methods in molecular biology (Clifton, N.J.)

Avec: Kartikeya Tiwari , Ritesh Kumar , Prakash Saudagar

In Vitro Assay for the Assessment of Oxygen Depletion Triggers in Human Cell Lines, Associated with Improving Responses to Cancer Therapy.

Methods in molecular biology (Clifton, N.J.)

Avec: Kartikeya Tiwari , Ritesh Kumar , Gundappa Saha , Prakash Saudagar

4',7-dihydroxyflavone conjugated carbon nanotube formulation demonstrates improved efficacy against Leishmania parasite.

Biochimica et biophysica acta. General subjects

Avec: Santanu Sasidharan , Prakash Saudagar

Green-Synthesized FeSO4 Nanoparticles Exhibit Antibacterial and Cytotoxic Activity by DNA Degradation.

Current pharmaceutical biotechnology

Avec: B Bharath , Santanu Sasidharan , Sai K Bhamidipati , Prakash Saudagar

Biochemical characterization and chemical validation of Leishmania MAP Kinase-3 as a potential drug target.

Scientific reports

Avec: Shweta Raj , Gundappa Saha , Santanu Sasidharan , Vikash Kumar Dubey , Prakash Saudagar

Concerted motion of structure and active site charge is required for tyrosine aminotransferase activity in Leishmania parasite.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy

Avec: Santanu Sasidharan , Prakash Saudagar

Pharmacophore-guided drug design using LdNMT as a model drug target for leishmaniasis.

Journal of biomolecular structure & dynamics

Avec: Banesh Sooram , Uppuladinne Mallikarjunachari , Sonavane Uddavesh , Prakash Saudagar

A novel approach to design chimeric multi epitope vaccine against

Heliyon

Avec: Sooram Banesh , Neharika Gupta , Chethireddy Vihadhar Reddy , Uppuladinne Mallikarjunachari , Nupoor Patil , Sonavane Uddhavesh , Prakash Saudagar

Bacterial protein azurin and derived peptides as potential anti-SARS-CoV-2 agents: insights from molecular docking and molecular dynamics simulations.

Journal of biomolecular structure & dynamics

Avec: Santanu Sasidharan , Chandrabose Selvaraj , Sanjeev Kumar Singh , Vikash Kumar Dubey , Sachin Kumar , Arsenio M Fialho , Prakash Saudagar

Identification of lead molecules against potential drug target protein MAPK4 from L. donovani: An in-silico approach using docking, molecular dynamics and binding free energy calculation.

PloS one

Avec: Shweta Raj , Santanu Sasidharan , Vikash Kumar Dubey , Prakash Saudagar

Biochemical and structural characterization of tyrosine aminotransferase suggests broad substrate specificity and a two-state folding mechanism in Leishmania donovani.

FEBS open bio

Avec: Santanu Sasidharan , Prakash Saudagar

Discovery of compounds inhibiting SARS-COV-2 multi-targets.

Journal of biomolecular structure & dynamics

Avec: Santanu Sasidharan , Neellohit Sarkar , Prakash Saudagar

Phase separation of FG-nucleoporins in nuclear pore complexes.

Biochimica et biophysica acta. Molecular cell research

Avec: Niharika Nag , Santanu Sasidharan , Vladimir N Uversky , Prakash Saudagar , Timir Tripathi

Deciphering the intrinsic dynamics of unphosphorylated IRAK4 kinase bound to type I and type II inhibitors.

Computers in biology and medicine

Avec: Vijayakumar Gosu , Santanu Sasidharan , Prakash Saudagar , Kamalakannan Radhakrishnan , Hak-Kyo Lee , Donghyun Shin

Mapping N- and C-terminals of Leishmania donovani tyrosine aminotransferase by gene truncation strategy: a functional study using in vitro and in silico approaches.

Scientific reports

Avec: Santanu Sasidharan , Prakash Saudagar

Flavones reversibly inhibit Leishmania donovani tyrosine aminotransferase by binding to the catalytic pocket: An integrated in silico-in vitro approach.

International journal of biological macromolecules

Avec: Santanu Sasidharan , Prakash Saudagar

Episomal expression of human glutathione reductase (HuGR) in Leishmania sheds light on evolutionary pressure for unique redox metabolism pathway: Impaired stress tolerance ability of Leishmania donovani.

International journal of biological macromolecules

Avec: Jay Prakash , Sunita Yadav , Gundappa Saha , Adarsh Kumar Chiranjivi , Suresh Kumar , Santanu Sasidharan , Prakash Saudagar , Vikash Kumar Dubey

Computational Insights into the Structural Dynamics of MDA5 Variants Associated with Aicardi-Goutières Syndrome and Singleton-Merten Syndrome.

Biomolecules

Avec: Vijayakumar Gosu , Santanu Sasidharan , Prakash Saudagar , Hak-Kyo Lee , Donghyun Shin

Amyloid Cross-Seeding: Mechanism, Implication, and Inhibition.

Molecules (Basel, Switzerland)

Avec: Sushma Subedi , Santanu Sasidharan , Niharika Nag , Prakash Saudagar , Timir Tripathi

Interface-based design of the favipiravir-binding site in SARS-CoV-2 RNA-dependent RNA polymerase reveals mutations conferring resistance to chain termination.

FEBS letters

Avec: Aditya K Padhi , Jagneshwar Dandapat , Prakash Saudagar , Vladimir N Uversky , Timir Tripathi

Gene Alterations Induced by Glutamine (Q) Encoding CAG Repeats Associated with Neurodegeneration.

Methods in molecular biology (Clifton, N.J.)

Avec: Gundappa Saha , Sukanya Ghosh , Vikash Kumar Dubey , Prakash Saudagar

Knockout of Tyrosine Aminotransferase Gene by Homologous Recombination Arrests Growth and Disrupts Redox Homeostasis in Leishmania Parasite.

Parasitology research

Avec: Santanu Sasidharan , Prakash Saudagar

Molecular dynamics of the ERRγ ligand-binding domain bound with agonist and inverse agonist.

PloS one

Avec: Santanu Sasidharan , Kamalakannan Radhakrishnan , Jun-Yeong Lee , Prakash Saudagar , Vijayakumar Gosu , Donghyun Shin

Therapeutic p28 peptide targets essential H1N1 influenza virus proteins: insights from docking and molecular dynamics simulations.

Molecular diversity

Avec: Santanu Sasidharan , Vijayakumar Gosu , Donghyun Shin , Subhradip Nath , Timir Tripathi , Prakash Saudagar

Leishmaniasis: where are we and where are we heading?

Parasitology research

Avec: Santanu Sasidharan , Prakash Saudagar

High-throughput rational design of the remdesivir binding site in the RdRp of SARS-CoV-2: implications for potential resistance.

iScience

Avec: Aditya K Padhi , Rohit Shukla , Prakash Saudagar , Timir Tripathi

Protective effect of SKB_Gutbiotic against castor oil and E.coli induced diarrhea in laboratory animals.

Microbial pathogenesis

Avec: Hemant Vanjari , Mahalaxmi Mohan , Parag Saudagar , Gitesh Guthale , Mitali Dalvi

Computational design of a potential multi-epitope subunit vaccine using immunoinformatics to fight Ebola virus.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases

Avec: Ajinkya Kadam , Santanu Sasidharan , Prakash Saudagar

Critical Insight into Plausible Acquired Tocopherol Pathway in Neglected Human Trypanosomatids.

ACS omega

Avec: Santanu Sasidharan , Timir Tripathi , Prakash Saudagar

WITHDRAWN: Recent Advances and Reports on Encapsulation in the Food Matrix: A Review

Current pharmaceutical biotechnology

Avec: Shital B Potdar , Prakash Saudagar , Irina Potoroko , Uday Bagale , Shriram Sonawane , Shirish H Sonawane

Gold and silver nanoparticles functionalized with 4',7-dihydroxyflavone exhibit activity against Leishmania donovani.

Acta tropica

Avec: Santanu Sasidharan , Prakash Saudagar

Simplified CRISPR-Mediated DNA Editing in Multicellular Eukaryotes.

Methods in molecular biology (Clifton, N.J.)

Avec: Ritesh Kumar , Kartikeya Tiwari , Prakash Saudagar

An anti-leishmanial compound 4',7-dihydroxyflavone elicits ROS-mediated apoptosis-like death in Leishmania parasite.

The FEBS journal

Avec: Santanu Sasidharan , Prakash Saudagar

Design and evaluation of a multiepitope vaccine for pancreatic cancer using immune-dominant epitopes derived from the signature proteome in expression datasets.

Medical oncology (Northwood, London, England)

Avec: Sooram Banesh , Nupoor Patil , Vihadhar Reddy Chethireddy , Arnav Bhukmaria , Prakash Saudagar

Réseau de co-auteurs

Santanu Sasidharan 25 collaborations

Timir Tripathi 7 collaborations

Vikash Kumar Dubey 5 collaborations

Shweta Raj 4 collaborations

Gundappa Saha 4 collaborations

Vijayakumar Gosu 4 collaborations

Donghyun Shin 4 collaborations

Kartikeya Tiwari 3 collaborations

Ritesh Kumar 3 collaborations

Mahalaxmi Mohan 2 collaborations

Parag Saudagar 2 collaborations

Uppuladinne Mallikarjunachari 2 collaborations

Sooram Banesh 2 collaborations

Nupoor Patil 2 collaborations

Niharika Nag 2 collaborations

Vladimir N Uversky 2 collaborations

Kamalakannan Radhakrishnan 2 collaborations

Hak-Kyo Lee 2 collaborations

Aditya K Padhi 2 collaborations

S N Balaji 1 collaboration

Khushal Chaudhari 1 collaboration

Chetna Sable 1 collaboration

Sominath Shinde 1 collaboration

Dattatray Bedade 1 collaboration

B Bharath 1 collaboration

Sai K Bhamidipati 1 collaboration

Banesh Sooram 1 collaboration

Sonavane Uddavesh 1 collaboration

Neharika Gupta 1 collaboration

Chethireddy Vihadhar Reddy 1 collaboration

Sonavane Uddhavesh 1 collaboration

Chandrabose Selvaraj 1 collaboration

Sanjeev Kumar Singh 1 collaboration

Sachin Kumar 1 collaboration

Arsenio M Fialho 1 collaboration

Neellohit Sarkar 1 collaboration

Jay Prakash 1 collaboration

Sunita Yadav 1 collaboration

Adarsh Kumar Chiranjivi 1 collaboration

Suresh Kumar 1 collaboration

Sushma Subedi 1 collaboration

Jagneshwar Dandapat 1 collaboration

Sukanya Ghosh 1 collaboration

Jun-Yeong Lee 1 collaboration

Subhradip Nath 1 collaboration

Rohit Shukla 1 collaboration

Hemant Vanjari 1 collaboration

Gitesh Guthale 1 collaboration

Mitali Dalvi 1 collaboration

Ajinkya Kadam 1 collaboration

Shital B Potdar 1 collaboration

Irina Potoroko 1 collaboration

Uday Bagale 1 collaboration

Shriram Sonawane 1 collaboration

Shirish H Sonawane 1 collaboration

Vihadhar Reddy Chethireddy 1 collaboration

Arnav Bhukmaria 1 collaboration