Rebecca Nedellec

Affiliations

Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037, USA.
International AIDS Vaccine Initiative-Neutralizing Antibody Center (IAVI-NAC), The Scripps Research Institute, La Jolla, CA 92037, USA.
Center for HIV/AIDS Vaccine Development (CHAVD), The Scripps Research Institute, La Jolla, CA 92037, USA.

Publications (12)

HIV envelope trimer-elicited autologous neutralizing antibodies bind a region overlapping the N332 glycan supersite.

Science advances

Avec: Bartek Nogal , Laura E McCoy , Marit J van Gils , Christopher A Cottrell , James E Voss , Raiees Andrabi , Matthias Pauthner , Chi-Hui Liang , Terrence Messmer , Rebecca Nedellec , Mia Shin , Hannah L Turner , Gabriel Ozorowski , Rogier W Sanders , Dennis R Burton , Andrew B Ward

Potent antibody-dependent cellular cytotoxicity of a V2-specific antibody is not sufficient for protection of macaques against SIV challenge.

PLoS pathogens

Avec: Michael W Grunst , Hwi Min Gil , Andres G Grandea , Brian J Snow , Raiees Andrabi , Rebecca Nedellec , Iszac Burton , Natasha M Clark , Sanath Kumar Janaka , Nida K Keles , Ryan V Moriarty , Andrea M Weiler , Saverio Capuano , Christine M Fennessey , Thomas C Friedrich , Shelby L O'Connor , David H O'Connor , Aimee T Broman , Brandon F Keele , Jeffrey D Lifson , Lars Hangartner , Dennis R Burton , David T Evans

Effector function does not contribute to protection from virus challenge by a highly potent HIV broadly neutralizing antibody in nonhuman primates.

Science translational medicine

Avec: Lars Hangartner , David Beauparlant , Eva Rakasz , Rebecca Nedellec , Nathanaël Hozé , Katherine McKenney , Mauricio A Martins , Gemma E Seabright , Joel D Allen , Andrea M Weiler , Thomas C Friedrich , Roland R Regoes , Max Crispin , Dennis R Burton

Mapping Neutralizing Antibody Epitope Specificities to an HIV Env Trimer in Immunized and in Infected Rhesus Macaques.

Cell reports

Avec: Fangzhu Zhao , Collin Joyce , Alison Burns , Bartek Nogal , Christopher A Cottrell , Alejandra Ramos , Trevor Biddle , Matthias Pauthner , Rebecca Nedellec , Huma Qureshi , Rosemarie Mason , Elise Landais , Bryan Briney , Andrew B Ward , Dennis R Burton , Devin Sok

Passive Transfer of Vaccine-Elicited Antibodies Protects against SIV in Rhesus Macaques.

Cell

Avec: Galit Alter , Wen-Han Yu , Abishek Chandrashekar , Erica N Borducchi , Khader Ghneim , Ashish Sharma , Rebecca Nedellec , Katherine R McKenney , Caitlyn Linde , Thomas Broge , Todd J Suscovich , Tom Linnekin , Peter Abbink , Noe B Mercado , Joseph P Nkolola , Katherine McMahan , Esther A Bondzie , Venous Hamza , Lauren Peter , Nicole Kordana , Shant Mahrokhian , Michael S Seaman , Wenjun Li , Mark G Lewis , Douglas A Lauffenburger , Lars Hangartner , Rafick-Pierre Sekaly , Dan H Barouch

Vaccine-Induced Protection from Homologous Tier 2 SHIV Challenge in Nonhuman Primates Depends on Serum-Neutralizing Antibody Titers.

Immunity

Avec: Matthias G Pauthner , Joseph P Nkolola , Colin Havenar-Daughton , Ben Murrell , Samantha M Reiss , Raiza Bastidas , Jérémie Prévost , Rebecca Nedellec , Benjamin von Bredow , Peter Abbink , Christopher A Cottrell , Daniel W Kulp , Talar Tokatlian , Bartek Nogal , Matteo Bianchi , Hui Li , Jeong Hyun Lee , Salvatore T Butera , David T Evans , Lars Hangartner , Andrés Finzi , Ian A Wilson , Richard T Wyatt , Darrell J Irvine , William R Schief , Andrew B Ward , Rogier W Sanders , Shane Crotty , George M Shaw , Dan H Barouch , Dennis R Burton

Molecular insights into antibody-mediated protection against the prototypic simian immunodeficiency virus.

Nature communications

Avec: Fangzhu Zhao , Zachary T Berndsen , Nuria Pedreño-Lopez , Alison Burns , Joel D Allen , Shawn Barman , Wen-Hsin Lee , Srirupa Chakraborty , Sandrasegaram Gnanakaran , Leigh M Sewall , Gabriel Ozorowski , Oliver Limbo , Ge Song , Peter Yong , Sean Callaghan , Jessica Coppola , Kim L Weisgrau , Jeffrey D Lifson , Rebecca Nedellec , Thomas B Voigt , Fernanda Laurino , Johan Louw , Brandon C Rosen , Michael Ricciardi , Max Crispin , Ronald C Desrosiers , Eva G Rakasz , David I Watkins , Raiees Andrabi , Andrew B Ward , Dennis R Burton , Devin Sok

Tissue-resident memory T cells trigger rapid exudation and local antibody accumulation.

Mucosal immunology

Avec: Pamela C Rosato , Sahar Lotfi-Emran , Vineet Joag , Sathi Wijeyesinghe , Clare F Quarnstrom , Hanna N Degefu , Rebecca Nedellec , Jason M Schenkel , Lalit K Beura , Lars Hangartner , Dennis R Burton , David Masopust

Antigen pressure from two founder viruses induces multiple insertions at a single antibody position to generate broadly neutralizing HIV antibodies.

PLoS pathogens

Avec: Collin Joyce , Sasha Murrell , Ben Murrell , Oluwarotimi Omorodion , Lorena S Ver , Nancy Carrico , Raiza Bastidas , Rebecca Nedellec , Michael Bick , Jordan Woehl , Fangzhu Zhao , Alison Burns , Shawn Barman , Michael Appel , Alejandra Ramos , Lalinda Wickramasinghe , Kemal Eren , Thomas Vollbrecht , Davey M Smith , Sergei L Kosakovsky Pond , Ryan McBride , Charli Worth , Facundo Batista , Devin Sok , Auteur inconnu , Pascal Poignard , Bryan Briney , Ian A Wilson , Elise Landais , Dennis R Burton

Long-primed germinal centres with enduring affinity maturation and clonal migration.

Nature

Avec: Jeong Hyun Lee , Henry J Sutton , Christopher A Cottrell , Ivy Phung , Gabriel Ozorowski , Leigh M Sewall , Rebecca Nedellec , Catherine Nakao , Murillo Silva , Sara T Richey , Jonathan L Torres , Wen-Hsin Lee , Erik Georgeson , Michael Kubitz , Sam Hodges , Tina-Marie Mullen , Yumiko Adachi , Kimberly M Cirelli , Amitinder Kaur , Carolina Allers , Marissa Fahlberg , Brooke F Grasperge , Jason P Dufour , Faith Schiro , Pyone P Aye , Oleksandr Kalyuzhniy , Alessia Liguori , Diane G Carnathan , Guido Silvestri , Xiaoying Shen , David C Montefiori , Ronald S Veazey , Andrew B Ward , Lars Hangartner , Dennis R Burton , Darrell J Irvine , William R Schief , Shane Crotty

A combined adjuvant approach primes robust germinal center responses and humoral immunity in non-human primates.

Nature communications

Avec: Ivy Phung , Kristen A Rodrigues , Ester Marina-Zárate , Laura Maiorino , Bapi Pahar , Wen-Hsin Lee , Mariane Melo , Amitinder Kaur , Carolina Allers , Marissa Fahlberg , Brooke F Grasperge , Jason P Dufour , Faith Schiro , Pyone P Aye , Paul G Lopez , Jonathan L Torres , Gabriel Ozorowski , Saman Eskandarzadeh , Michael Kubitz , Erik Georgeson , Bettina Groschel , Rebecca Nedellec , Michael Bick , Katarzyna Kaczmarek Michaels , Hongmei Gao , Xiaoying Shen , Diane G Carnathan , Guido Silvestri , David C Montefiori , Andrew B Ward , Lars Hangartner , Ronald S Veazey , Dennis R Burton , William R Schief , Darrell J Irvine , Shane Crotty

Modulation of antigen delivery and lymph node activation in non-human primates by saponin adjuvant SMNP.

bioRxiv : the preprint server for biology

Avec: Parisa Yousefpour , Yiming J Zhang , Laura Maiorino , Mariane B Melo , Mariluz A Arainga Ramirez , Sidath C Kumarapperuma , Peng Xiao , Murillo Silva , Na Li , Katarzyna K Michaels , Erik Georgeson , Saman Eskandarzadeh , Michael Kubitz , Bettina Groschel , Kashif Qureshi , Jane Fontenot , Lars Hangartner , Rebecca Nedellec , J Christopher Love , Dennis R Burton , William R Schief , Francois J Villinger , Darrell J Irvine

Réseau de co-auteurs

Dennis R Burton 11 collaborations

Lars Hangartner 8 collaborations

Andrew B Ward 6 collaborations

Christopher A Cottrell 4 collaborations

Gabriel Ozorowski 4 collaborations

Darrell J Irvine 4 collaborations

William R Schief 4 collaborations

Bartek Nogal 3 collaborations

Raiees Andrabi 3 collaborations

Fangzhu Zhao 3 collaborations

Alison Burns 3 collaborations

Devin Sok 3 collaborations

Shane Crotty 3 collaborations

Wen-Hsin Lee 3 collaborations

Erik Georgeson 3 collaborations

Michael Kubitz 3 collaborations

Matthias Pauthner 2 collaborations

Rogier W Sanders 2 collaborations

Andrea M Weiler 2 collaborations

Thomas C Friedrich 2 collaborations

Jeffrey D Lifson 2 collaborations

David T Evans 2 collaborations

Joel D Allen 2 collaborations

Max Crispin 2 collaborations

Collin Joyce 2 collaborations

Alejandra Ramos 2 collaborations

Elise Landais 2 collaborations

Bryan Briney 2 collaborations

Peter Abbink 2 collaborations

Joseph P Nkolola 2 collaborations

Dan H Barouch 2 collaborations

Ben Murrell 2 collaborations

Raiza Bastidas 2 collaborations

Jeong Hyun Lee 2 collaborations

Ian A Wilson 2 collaborations

Shawn Barman 2 collaborations

Leigh M Sewall 2 collaborations

Michael Bick 2 collaborations

Ivy Phung 2 collaborations

Murillo Silva 2 collaborations

Jonathan L Torres 2 collaborations

Amitinder Kaur 2 collaborations

Carolina Allers 2 collaborations

Marissa Fahlberg 2 collaborations

Brooke F Grasperge 2 collaborations

Jason P Dufour 2 collaborations

Faith Schiro 2 collaborations

Pyone P Aye 2 collaborations

Diane G Carnathan 2 collaborations

Guido Silvestri 2 collaborations

Xiaoying Shen 2 collaborations

David C Montefiori 2 collaborations

Ronald S Veazey 2 collaborations

Laura Maiorino 2 collaborations

Saman Eskandarzadeh 2 collaborations

Bettina Groschel 2 collaborations

Laura E McCoy 1 collaboration

Marit J van Gils 1 collaboration

James E Voss 1 collaboration

Chi-Hui Liang 1 collaboration

Terrence Messmer 1 collaboration

Mia Shin 1 collaboration

Hannah L Turner 1 collaboration

Michael W Grunst 1 collaboration

Hwi Min Gil 1 collaboration

Andres G Grandea 1 collaboration

Brian J Snow 1 collaboration

Iszac Burton 1 collaboration

Natasha M Clark 1 collaboration

Sanath Kumar Janaka 1 collaboration

Nida K Keles 1 collaboration

Ryan V Moriarty 1 collaboration

Saverio Capuano 1 collaboration

Christine M Fennessey 1 collaboration

Shelby L O'Connor 1 collaboration

David H O'Connor 1 collaboration

Aimee T Broman 1 collaboration

Brandon F Keele 1 collaboration

David Beauparlant 1 collaboration

Eva Rakasz 1 collaboration

Nathanaël Hozé 1 collaboration

Katherine McKenney 1 collaboration

Mauricio A Martins 1 collaboration

Gemma E Seabright 1 collaboration

Roland R Regoes 1 collaboration

Trevor Biddle 1 collaboration

Huma Qureshi 1 collaboration

Rosemarie Mason 1 collaboration

Galit Alter 1 collaboration

Wen-Han Yu 1 collaboration

Abishek Chandrashekar 1 collaboration

Erica N Borducchi 1 collaboration

Khader Ghneim 1 collaboration

Ashish Sharma 1 collaboration

Katherine R McKenney 1 collaboration

Caitlyn Linde 1 collaboration

Thomas Broge 1 collaboration

Todd J Suscovich 1 collaboration

Tom Linnekin 1 collaboration

Noe B Mercado 1 collaboration

Katherine McMahan 1 collaboration

Esther A Bondzie 1 collaboration

Venous Hamza 1 collaboration

Lauren Peter 1 collaboration

Nicole Kordana 1 collaboration

Shant Mahrokhian 1 collaboration

Michael S Seaman 1 collaboration

Wenjun Li 1 collaboration

Mark G Lewis 1 collaboration

Douglas A Lauffenburger 1 collaboration

Rafick-Pierre Sekaly 1 collaboration

Matthias G Pauthner 1 collaboration

Colin Havenar-Daughton 1 collaboration

Samantha M Reiss 1 collaboration

Jérémie Prévost 1 collaboration

Benjamin von Bredow 1 collaboration

Daniel W Kulp 1 collaboration

Talar Tokatlian 1 collaboration

Matteo Bianchi 1 collaboration

Hui Li 1 collaboration

Salvatore T Butera 1 collaboration

Andrés Finzi 1 collaboration

Richard T Wyatt 1 collaboration

George M Shaw 1 collaboration

Zachary T Berndsen 1 collaboration

Nuria Pedreño-Lopez 1 collaboration

Srirupa Chakraborty 1 collaboration

Sandrasegaram Gnanakaran 1 collaboration

Oliver Limbo 1 collaboration

Ge Song 1 collaboration

Peter Yong 1 collaboration

Sean Callaghan 1 collaboration

Jessica Coppola 1 collaboration

Kim L Weisgrau 1 collaboration

Thomas B Voigt 1 collaboration

Fernanda Laurino 1 collaboration

Johan Louw 1 collaboration

Brandon C Rosen 1 collaboration

Michael Ricciardi 1 collaboration

Ronald C Desrosiers 1 collaboration

Eva G Rakasz 1 collaboration

David I Watkins 1 collaboration

Pamela C Rosato 1 collaboration

Sahar Lotfi-Emran 1 collaboration

Vineet Joag 1 collaboration

Sathi Wijeyesinghe 1 collaboration

Clare F Quarnstrom 1 collaboration

Hanna N Degefu 1 collaboration

Jason M Schenkel 1 collaboration

Lalit K Beura 1 collaboration

David Masopust 1 collaboration

Sasha Murrell 1 collaboration

Oluwarotimi Omorodion 1 collaboration

Lorena S Ver 1 collaboration

Nancy Carrico 1 collaboration

Jordan Woehl 1 collaboration

Michael Appel 1 collaboration

Lalinda Wickramasinghe 1 collaboration

Kemal Eren 1 collaboration

Thomas Vollbrecht 1 collaboration

Davey M Smith 1 collaboration

Sergei L Kosakovsky Pond 1 collaboration

Ryan McBride 1 collaboration

Charli Worth 1 collaboration

Facundo Batista 1 collaboration

None None 1 collaboration

Pascal Poignard 1 collaboration

Henry J Sutton 1 collaboration

Catherine Nakao 1 collaboration

Sara T Richey 1 collaboration

Sam Hodges 1 collaboration

Tina-Marie Mullen 1 collaboration

Yumiko Adachi 1 collaboration

Kimberly M Cirelli 1 collaboration

Oleksandr Kalyuzhniy 1 collaboration

Alessia Liguori 1 collaboration

Kristen A Rodrigues 1 collaboration

Ester Marina-Zárate 1 collaboration

Bapi Pahar 1 collaboration

Mariane Melo 1 collaboration

Paul G Lopez 1 collaboration

Katarzyna Kaczmarek Michaels 1 collaboration

Hongmei Gao 1 collaboration

Parisa Yousefpour 1 collaboration

Yiming J Zhang 1 collaboration

Mariane B Melo 1 collaboration

Mariluz A Arainga Ramirez 1 collaboration

Sidath C Kumarapperuma 1 collaboration

Peng Xiao 1 collaboration

Na Li 1 collaboration

Katarzyna K Michaels 1 collaboration

Kashif Qureshi 1 collaboration

Jane Fontenot 1 collaboration

J Christopher Love 1 collaboration

Francois J Villinger 1 collaboration