Reiner Class

Affiliations

UCB Biopharma SRL, Braine-l'Alleud, Belgium.

Publications (5)

The Promise of AI for DILI Prediction.

Frontiers in artificial intelligence

Avec: Andreu Vall , Yogesh Sabnis , Jiye Shi , Reiner Class , Sepp Hochreiter , Günter Klambauer

Discovery and Characterization of Potent, Efficacious, Orally Available Antimalarial Plasmepsin X Inhibitors and Preclinical Safety Assessment of

Journal of medicinal chemistry

Avec: Martin A Lowe , Alvaro Cardenas , Jean-Pierre Valentin , Zhaoning Zhu , Jan Abendroth , Jose L Castro , Reiner Class , Annie Delaunois , Renaud Fleurance , Helga Gerets , Vitalina Gryshkova , Lloyd King , Donald D Lorimer , Malcolm MacCoss , Julian H Rowley , Marie-Luce Rosseels , Leandro Royer , Richard D Taylor , Melanie Wong , Oliver Zaccheo , Vishal P Chavan , Gokul A Ghule , Bapusaheb K Tapkir , Jeremy N Burrows , Maëlle Duffey , Matthias Rottmann , Sergio Wittlin , Iñigo Angulo-Barturen , María Belén Jiménez-Díaz , Josefine Striepen , Kate J Fairhurst , Tomas Yeo , David A Fidock , Alan F Cowman , Paola Favuzza , Benigno Crespo-Fernandez , Francisco Javier Gamo , Daniel E Goldberg , Dominique Soldati-Favre , Benoît Laleu , Teresa de Haro

Assessing the interplay between off-target promiscuity, cytotoxicity, and tolerability in rodents to improve the safety profile of novel anti-malarial plasmepsin X inhibitors.

Toxicological sciences : an official journal of the Society of Toxicology

Avec: Helga H J Gerets , Annie Delaunois , Alvaro Cardenas , Reiner Class , Renaud Fleurance , Teresa de Haro , Benoît Laleu , Martin A Lowe , Marie-Luce Rosseels , Jean-Pierre Valentin

Setup of human liver-chips integrating 3D models, microwells and a standardized microfluidic platform as proof-of-concept study to support drug evaluation.

Biomaterials and biosystems

Avec: Benoit Cox , Patrick Barton , Reiner Class , Hannah Coxhead , Claude Delatour , Eric Gillent , Jamie Henshall , Emre M Isin , Lloyd King , Jean-Pierre Valentin

A Perfused In Vitro Human iPSC-Derived Blood-Brain Barrier Faithfully Mimics Transferrin Receptor-Mediated Transcytosis of Therapeutic Antibodies.

Cellular and molecular neurobiology

Avec: Floriana Burgio , Carine Gaiser , Kevin Brady , Viviana Gatta , Reiner Class , Ramona Schrage , Laura Suter-Dick

Réseau de co-auteurs

Jean-Pierre Valentin 3 collaborations

Martin A Lowe 2 collaborations

Alvaro Cardenas 2 collaborations

Annie Delaunois 2 collaborations

Renaud Fleurance 2 collaborations

Lloyd King 2 collaborations

Marie-Luce Rosseels 2 collaborations

Benoît Laleu 2 collaborations

Teresa de Haro 2 collaborations

Andreu Vall 1 collaboration

Yogesh Sabnis 1 collaboration

Jiye Shi 1 collaboration

Sepp Hochreiter 1 collaboration

Günter Klambauer 1 collaboration

Zhaoning Zhu 1 collaboration

Jan Abendroth 1 collaboration

Jose L Castro 1 collaboration

Helga Gerets 1 collaboration

Vitalina Gryshkova 1 collaboration

Donald D Lorimer 1 collaboration

Malcolm MacCoss 1 collaboration

Julian H Rowley 1 collaboration

Leandro Royer 1 collaboration

Richard D Taylor 1 collaboration

Melanie Wong 1 collaboration

Oliver Zaccheo 1 collaboration

Vishal P Chavan 1 collaboration

Gokul A Ghule 1 collaboration

Bapusaheb K Tapkir 1 collaboration

Jeremy N Burrows 1 collaboration

Maëlle Duffey 1 collaboration

Matthias Rottmann 1 collaboration

Sergio Wittlin 1 collaboration

Iñigo Angulo-Barturen 1 collaboration

María Belén Jiménez-Díaz 1 collaboration

Josefine Striepen 1 collaboration

Kate J Fairhurst 1 collaboration

Tomas Yeo 1 collaboration

David A Fidock 1 collaboration

Alan F Cowman 1 collaboration

Paola Favuzza 1 collaboration

Benigno Crespo-Fernandez 1 collaboration

Francisco Javier Gamo 1 collaboration

Daniel E Goldberg 1 collaboration

Dominique Soldati-Favre 1 collaboration

Helga H J Gerets 1 collaboration

Benoit Cox 1 collaboration

Patrick Barton 1 collaboration

Hannah Coxhead 1 collaboration

Claude Delatour 1 collaboration

Eric Gillent 1 collaboration

Jamie Henshall 1 collaboration

Emre M Isin 1 collaboration

Floriana Burgio 1 collaboration

Carine Gaiser 1 collaboration

Kevin Brady 1 collaboration

Viviana Gatta 1 collaboration

Ramona Schrage 1 collaboration

Laura Suter-Dick 1 collaboration