Sander Busker

Affiliations

Department of Medical Biochemistry, Karolinska Institutet, Solnavägen 9, 17177 Stockholm, Sweden.

ORCID: 0000-0002-7069-3864

Publications (5)

Selective, Modular Probes for Thioredoxins Enabled by Rational Tuning of a Unique Disulfide Structure Motif.

Journal of the American Chemical Society

Avec: Jan G Felber , Lukas Zeisel , Lena Poczka , Karoline Scholzen , Sander Busker , Martin S Maier , Ulrike Theisen , Christina Brandstädter , Katja Becker , Elias S J Arnér , Julia Thorn-Seshold , Oliver Thorn-Seshold

To inhibit TrxR1 is to inactivate STAT3-Inhibition of TrxR1 enzymatic function by STAT3 small molecule inhibitors.

Redox biology

Avec: Sander Busker , Brent Page , Elias S J Arnér

Irreversible TrxR1 inhibitors block STAT3 activity and induce cancer cell death.

Science advances

Avec: S Busker , W Qian , M Haraldsson , B Espinosa , L Johansson , S Attarha , I Kolosenko , J Liu , M Dagnell , D Grandér , E S J Arnér , K Pokrovskaja Tamm , B D G Page

Cyclic 5-membered disulfides are not selective substrates of thioredoxin reductase, but are opened nonspecifically.

Nature communications

Avec: Jan G Felber , Lena Poczka , Karoline C Scholzen , Lukas Zeisel , Martin S Maier , Sander Busker , Ulrike Theisen , Christina Brandstädter , Katja Becker , Elias S J Arnér , Julia Thorn-Seshold , Oliver Thorn-Seshold

Validating Signal Transducer and Activator of Transcription (STAT) Protein-Inhibitor Interactions Using Biochemical and Cellular Thermal Shift Assays.

ACS chemical biology

Avec: Sanaz Attarha , Anja Reithmeier , Sander Busker , Matthieu Desroses , Brent D G Page

Réseau de co-auteurs

Elias S J Arnér 3 collaborations

Jan G Felber 2 collaborations

Lukas Zeisel 2 collaborations

Lena Poczka 2 collaborations

Martin S Maier 2 collaborations

Ulrike Theisen 2 collaborations

Christina Brandstädter 2 collaborations

Katja Becker 2 collaborations

Julia Thorn-Seshold 2 collaborations

Oliver Thorn-Seshold 2 collaborations

Karoline Scholzen 1 collaboration

Brent Page 1 collaboration

S Busker 1 collaboration

W Qian 1 collaboration

M Haraldsson 1 collaboration

B Espinosa 1 collaboration

L Johansson 1 collaboration

S Attarha 1 collaboration

I Kolosenko 1 collaboration

J Liu 1 collaboration

M Dagnell 1 collaboration

D Grandér 1 collaboration

E S J Arnér 1 collaboration

K Pokrovskaja Tamm 1 collaboration

B D G Page 1 collaboration

Karoline C Scholzen 1 collaboration

Sanaz Attarha 1 collaboration

Anja Reithmeier 1 collaboration

Matthieu Desroses 1 collaboration

Brent D G Page 1 collaboration