Sebastien Benzekry

Affiliations

Iowa State University College of Veterinary Medicine, Ames, Iowa, USA.
Team Modelisation en Oncologie, Inria Bordeaux Sud-Ouest, Institut de Mathématiques de Bordeaux, Talence, France.

Publications (21)

Optimal Scheduling of Bevacizumab and Pemetrexed/Cisplatin Dosing in Non-Small Cell Lung Cancer.

CPT: pharmacometrics & systems pharmacology

Avec: Benjamin K Schneider , Arnaud Boyer , Joseph Ciccolini , Fabrice Barlesi , Kenneth Wang , Sebastien Benzekry , Jonathan P Mochel

A Senescence-Mimicking (Senomimetic) VEGFR TKI Side Effect Primes Tumor Immune Responses via IFN/STING Signaling.

Molecular cancer therapeutics

Avec: Melissa Dolan , Yuhao Shi , Michalis Mastri , Mark D Long , Amber McKenery , James W Hill , Cristina Vaghi , Sebastien Benzekry , Joseph Barbi , John M L Ebos

Macro-scale models for fluid flow in tumour tissues: impact of microstructure properties.

Journal of mathematical biology

Avec: Cristina Vaghi , Raphaëlle Fanciullino , Sébastien Benzekry , Clair Poignard

Practical identifiability analysis of a mechanistic model for the time to distant metastatic relapse and its application to renal cell carcinoma.

PLoS computational biology

Avec: Arturo Álvarez-Arenas , Wilfried Souleyreau , Andrea Emanuelli , Lindsay S Cooley , Jean-Christophe Bernhard , Andreas Bikfalvi , Sebastien Benzekry

Mechanistic modeling of metastatic relapse in early breast cancer to investigate the biological impact of prognostic biomarkers.

Computer methods and programs in biomedicine

Avec: Célestin Bigarré , François Bertucci , Pascal Finetti , Gaëtan Macgrogan , Xavier Muracciole , Sébastien Benzekry

Reuniting philosophy and science to advance cancer research.

Biological reviews of the Cambridge Philosophical Society

Avec: Thomas Pradeu , Bertrand Daignan-Fornier , Andrew Ewald , Pierre-Luc Germain , Samir Okasha , Anya Plutynski , Sébastien Benzekry , Marta Bertolaso , Mina Bissell , Joel S Brown , Benjamin Chin-Yee , Ian Chin-Yee , Hans Clevers , Laurent Cognet , Marie Darrason , Emmanuel Farge , Jean Feunteun , Jérôme Galon , Elodie Giroux , Sara Green , Fridolin Gross , Fanny Jaulin , Rob Knight , Ezio Laconi , Nicolas Larmonier , Carlo Maley , Alberto Mantovani , Violaine Moreau , Pierre Nassoy , Elena Rondeau , David Santamaria , Catherine M Sawai , Andrei Seluanov , Gregory D Sepich-Poore , Vanja Sisirak , Eric Solary , Sarah Yvonnet , Lucie Laplane

A senescence-mimicking (senomimetic) VEGFR TKI side-effect primes tumor immune responses via IFN/STING signaling.

Molecular cancer therapeutics

Avec: Melissa Dolan , Yuhao Shi , Michalis Mastri , Mark D Long , Amber McKenery , James W Hill , Cristina Vaghi , Sebastien Benzekry , Joseph Barbi , John M L Ebos

Artificial Intelligence and Mechanistic Modeling for Clinical Decision Making in Oncology.

Clinical pharmacology and therapeutics

Avec: Sebastien Benzekry

Quantitative mathematical modeling of clinical brain metastasis dynamics in non-small cell lung cancer.

Scientific reports

Avec: M Bilous , C Serdjebi , A Boyer , P Tomasini , C Pouypoudat , D Barbolosi , F Barlesi , F Chomy , S Benzekry

Population modeling of tumor growth curves and the reduced Gompertz model improve prediction of the age of experimental tumors.

PLoS computational biology

Avec: Cristina Vaghi , Anne Rodallec , Raphaëlle Fanciullino , Joseph Ciccolini , Jonathan P Mochel , Michalis Mastri , Clair Poignard , John M L Ebos , Sébastien Benzekry

Machine Learning for Prediction of Immunotherapy Efficacy in Non-Small Cell Lung Cancer from Simple Clinical and Biological Data.

Cancers

Avec: Sébastien Benzekry , Mathieu Grangeon , Mélanie Karlsen , Maria Alexa , Isabella Bicalho-Frazeto , Solène Chaleat , Pascale Tomasini , Dominique Barbolosi , Fabrice Barlesi , Laurent Greillier

Experimental and computational modeling for signature and biomarker discovery of renal cell carcinoma progression.

Molecular cancer

Avec: Lindsay S Cooley , Justine Rudewicz , Wilfried Souleyreau , Andrea Emanuelli , Arturo Alvarez-Arenas , Kim Clarke , Francesco Falciani , Maeva Dufies , Diether Lambrechts , Elodie Modave , Domitille Chalopin-Fillot , Raphael Pineau , Damien Ambrosetti , Jean-Christophe Bernhard , Alain Ravaud , Sylvie Négrier , Jean-Marc Ferrero , Gilles Pagès , Sebastien Benzekry , Macha Nikolski , Andreas Bikfalvi

Tumor growth monitoring in breast cancer xenografts: A good technique for a strong ethic.

PloS one

Avec: Anne Rodallec , Cristina Vaghi , Joseph Ciccolini , Raphaelle Fanciullino , Sebastien Benzekry

CAR T Cell Immunotherapy in Human and Veterinary Oncology: Changing the Odds Against Hematological Malignancies.

The AAPS journal

Avec: Jonathan P Mochel , Stephen C Ekker , Chad M Johannes , Albert E Jergens , Karin Allenspach , Agnes Bourgois-Mochel , Michael Knouse , Sebastien Benzekry , Wesley Wierson , Amy K LeBlanc , Saad S Kenderian

Is There Any Room for Pharmacometrics With Immuno-Oncology Drugs? Input from the EORTC-PAMM Course on Preclinical and Early-phase Clinical Pharmacology.

Anticancer research

Avec: Anne Rodallec , Raphaelle Fanciullino , Sebastien Benzekry , Joseph Ciccolini , Auteur inconnu

Deciphering the response and resistance to immune-checkpoint inhibitors in lung cancer with artificial intelligence-based analysis: when PIONeeR meets QUANTIC.

British journal of cancer

Avec: Joseph Ciccolini , Sébastien Benzekry , Fabrice Barlesi

Machine Learning and Mechanistic Modeling for Prediction of Metastatic Relapse in Early-Stage Breast Cancer.

JCO clinical cancer informatics

Avec: Chiara Nicolò , Cynthia Périer , Melanie Prague , Carine Bellera , Gaëtan MacGrogan , Olivier Saut , Sébastien Benzekry

Development and Validation of a Prediction Model of Overall Survival in High-Risk Neuroblastoma Using Mechanistic Modeling of Metastasis.

JCO clinical cancer informatics

Avec: Sébastien Benzekry , Coline Sentis , Carole Coze , Laëtitia Tessonnier , Nicolas André

Computational markers for personalized prediction of outcomes in non-small cell lung cancer patients with brain metastases.

Clinical & experimental metastasis

Avec: Sébastien Benzekry , Pirmin Schlicke , Alice Mogenet , Laurent Greillier , Pascale Tomasini , Eléonore Simon

Machine-learning and mechanistic modeling of metastatic breast cancer after neoadjuvant treatment.

PLoS computational biology

Avec: Sebastien Benzekry , Michalis Mastri , Chiara Nicolò , John M L Ebos

Predicting Survival in Patients with Advanced NSCLC Treated with Atezolizumab Using Pre- and on-Treatment Prognostic Biomarkers.

Clinical pharmacology and therapeutics

Avec: Sébastien Benzekry , Mélanie Karlsen , Célestin Bigarré , Abdessamad El Kaoutari , Bruno Gomes , Martin Stern , Ales Neubert , Rene Bruno , François Mercier , Suresh Vatakuti , Peter Curle , Candice Jamois

Réseau de co-auteurs

Sébastien Benzekry 10 collaborations

Joseph Ciccolini 5 collaborations

Cristina Vaghi 5 collaborations

Michalis Mastri 4 collaborations

John M L Ebos 4 collaborations

Fabrice Barlesi 3 collaborations

Jonathan P Mochel 3 collaborations

Anne Rodallec 3 collaborations

Melissa Dolan 2 collaborations

Yuhao Shi 2 collaborations

Mark D Long 2 collaborations

Amber McKenery 2 collaborations

James W Hill 2 collaborations

Joseph Barbi 2 collaborations

Raphaëlle Fanciullino 2 collaborations

Clair Poignard 2 collaborations

Wilfried Souleyreau 2 collaborations

Andrea Emanuelli 2 collaborations

Lindsay S Cooley 2 collaborations

Jean-Christophe Bernhard 2 collaborations

Andreas Bikfalvi 2 collaborations

Célestin Bigarré 2 collaborations

Mélanie Karlsen 2 collaborations

Pascale Tomasini 2 collaborations

Laurent Greillier 2 collaborations

Raphaelle Fanciullino 2 collaborations

Chiara Nicolò 2 collaborations

Benjamin K Schneider 1 collaboration

Arnaud Boyer 1 collaboration

Kenneth Wang 1 collaboration

Arturo Álvarez-Arenas 1 collaboration

François Bertucci 1 collaboration

Pascal Finetti 1 collaboration

Gaëtan Macgrogan 1 collaboration

Xavier Muracciole 1 collaboration

Thomas Pradeu 1 collaboration

Bertrand Daignan-Fornier 1 collaboration

Andrew Ewald 1 collaboration

Pierre-Luc Germain 1 collaboration

Samir Okasha 1 collaboration

Anya Plutynski 1 collaboration

Marta Bertolaso 1 collaboration

Mina Bissell 1 collaboration

Joel S Brown 1 collaboration

Benjamin Chin-Yee 1 collaboration

Ian Chin-Yee 1 collaboration

Hans Clevers 1 collaboration

Laurent Cognet 1 collaboration

Marie Darrason 1 collaboration

Emmanuel Farge 1 collaboration

Jean Feunteun 1 collaboration

Jérôme Galon 1 collaboration

Elodie Giroux 1 collaboration

Sara Green 1 collaboration

Fridolin Gross 1 collaboration

Fanny Jaulin 1 collaboration

Rob Knight 1 collaboration

Ezio Laconi 1 collaboration

Nicolas Larmonier 1 collaboration

Carlo Maley 1 collaboration

Alberto Mantovani 1 collaboration

Violaine Moreau 1 collaboration

Pierre Nassoy 1 collaboration

Elena Rondeau 1 collaboration

David Santamaria 1 collaboration

Catherine M Sawai 1 collaboration

Andrei Seluanov 1 collaboration

Gregory D Sepich-Poore 1 collaboration

Vanja Sisirak 1 collaboration

Eric Solary 1 collaboration

Sarah Yvonnet 1 collaboration

Lucie Laplane 1 collaboration

M Bilous 1 collaboration

C Serdjebi 1 collaboration

A Boyer 1 collaboration

P Tomasini 1 collaboration

C Pouypoudat 1 collaboration

D Barbolosi 1 collaboration

F Barlesi 1 collaboration

F Chomy 1 collaboration

S Benzekry 1 collaboration

Mathieu Grangeon 1 collaboration

Maria Alexa 1 collaboration

Isabella Bicalho-Frazeto 1 collaboration

Solène Chaleat 1 collaboration

Dominique Barbolosi 1 collaboration

Justine Rudewicz 1 collaboration

Arturo Alvarez-Arenas 1 collaboration

Kim Clarke 1 collaboration

Francesco Falciani 1 collaboration

Maeva Dufies 1 collaboration

Diether Lambrechts 1 collaboration

Elodie Modave 1 collaboration

Domitille Chalopin-Fillot 1 collaboration

Raphael Pineau 1 collaboration

Damien Ambrosetti 1 collaboration

Alain Ravaud 1 collaboration

Sylvie Négrier 1 collaboration

Jean-Marc Ferrero 1 collaboration

Gilles Pagès 1 collaboration

Macha Nikolski 1 collaboration

Stephen C Ekker 1 collaboration

Chad M Johannes 1 collaboration

Albert E Jergens 1 collaboration

Karin Allenspach 1 collaboration

Agnes Bourgois-Mochel 1 collaboration

Michael Knouse 1 collaboration

Wesley Wierson 1 collaboration

Amy K LeBlanc 1 collaboration

Saad S Kenderian 1 collaboration

None None 1 collaboration

Cynthia Périer 1 collaboration

Melanie Prague 1 collaboration

Carine Bellera 1 collaboration

Gaëtan MacGrogan 1 collaboration

Olivier Saut 1 collaboration

Coline Sentis 1 collaboration

Carole Coze 1 collaboration

Laëtitia Tessonnier 1 collaboration

Nicolas André 1 collaboration

Pirmin Schlicke 1 collaboration

Alice Mogenet 1 collaboration

Eléonore Simon 1 collaboration

Abdessamad El Kaoutari 1 collaboration

Bruno Gomes 1 collaboration

Martin Stern 1 collaboration

Ales Neubert 1 collaboration

Rene Bruno 1 collaboration

François Mercier 1 collaboration

Suresh Vatakuti 1 collaboration

Peter Curle 1 collaboration

Candice Jamois 1 collaboration