Simone Filosto

Affiliations

From the H. Lee Moffitt Cancer Center, Tampa, FL (F.L.L.); Stanford University School of Medicine, Stanford (D.B.M.), and Kite, a Gilead company, Santa Monica (Y.Y., S.F., J.S., M.S., C.T., P.C.) - both in California; Dana-Farber Cancer Institute, Boston (C.A.J.); Memorial Sloan Kettering Cancer Center, New York (M.-A.P.), and the University of Rochester School of Medicine, Rochester (P.M.R.) - both in New York; Amsterdam Medical Center, University of Amsterdam, Cancer Center Amsterdam, Amsterdam (M.-J.K.), University Medical Center Groningen, Groningen (T.M.), and University Medical Center Utrecht, Utrecht (M.C.M.) - all in the Netherlands; Vanderbilt-Ingram Cancer Center (O.O.O.) and Sarah Cannon Research Institute and Tennessee Oncology (I.W.F.) - both in Nashville; Washington University School of Medicine, St. Louis (A.G.); the Marlene and Stewart Greenebaum Cancer Center, University of Maryland School of Medicine, Baltimore (A.P.R.); the University of Kansas Cancer Center, Kansas City (J. McGuirk); the Swedish Cancer Institute, Seattle (J.M.P.); Banner M.D. Anderson Cancer Center, Gilbert, AZ (J. Muñoz); the University of Iowa, Iowa City (U.F.); Bellvitge Institute for Biomedical Research, Universitat de Barcelona, Hematology Department, Institut Català d'Oncologia-Hospitalet, Barcelona (A.S.); University Hospitals Leuven, Leuven, Belgium (P.V.); the Division of Hematology, University of British Columbia and Leukemia-Bone Marrow Transplant Program of British Columbia, Vancouver General Hospital, BC Cancer, Vancouver, Canada (K.W.S.); Peter MacCallum Cancer Centre, Royal Melbourne Hospital and the University of Melbourne, Melbourne, VIC, Australia (M.D.); the University of Chicago Medical Center (P.A.R.) and Northwestern University Feinberg School of Medicine and the Robert H. Lurie Comprehensive Cancer Center of Northwestern University (L.I.G.) - both in Chicago; John Theurer Cancer Center, Hackensack, NJ (L.A.L.); the Centre for Clinical Haematology, University Hospitals Birmingham NHS Foundation Trust, Birmingham, United Kingdom (S.C.); and the University of Texas M.D. Anderson Cancer Center, Houston (J.R.W.).

Publications (10)

Axicabtagene Ciloleucel as Second-Line Therapy for Large B-Cell Lymphoma.

The New England journal of medicine

Avec: Frederick L Locke , David B Miklos , Caron A Jacobson , Miguel-Angel Perales , Marie-José Kersten , Olalekan O Oluwole , Armin Ghobadi , Aaron P Rapoport , Joseph McGuirk , John M Pagel , Javier Muñoz , Umar Farooq , Tom van Meerten , Patrick M Reagan , Anna Sureda , Ian W Flinn , Peter Vandenberghe , Kevin W Song , Michael Dickinson , Monique C Minnema , Peter A Riedell , Lori A Leslie , Sridhar Chaganti , Yin Yang , Simone Filosto , Jina Shah , Marco Schupp , Christina To , Paul Cheng , Leo I Gordon , Jason R Westin , Auteur inconnu

High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast Cancers.

Molecular cancer therapeutics

Avec: Simon J Anderhub , Grace Wing-Yan Mak , Mark D Gurden , Amir Faisal , Konstantinos Drosopoulos , Katie Walsh , Hannah L Woodward , Paolo Innocenti , Isaac M Westwood , Sébastien Naud , Angela Hayes , Efthymia Theofani , Simone Filosto , Harry Saville , Rosemary Burke , Rob L M van Montfort , Florence I Raynaud , Julian Blagg , Swen Hoelder , Suzanne A Eccles , Spiros Linardopoulos

Safety and Efficacy of Axicabtagene Ciloleucel versus Standard of Care in Patients 65 Years of Age or Older with Relapsed/Refractory Large B-Cell Lymphoma.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Jason R Westin , Frederick L Locke , Michael Dickinson , Armin Ghobadi , Mahmoud Elsawy , Tom van Meerten , David B Miklos , Matthew L Ulrickson , Miguel-Angel Perales , Umar Farooq , Luciano Wannesson , Lori Leslie , Marie José Kersten , Caron A Jacobson , John M Pagel , Gerald Wulf , Patrick Johnston , Aaron P Rapoport , Linqiu Du , Saran Vardhanabhuti , Simone Filosto , Jina Shah , Julia T Snider , Paul Cheng , Christina To , Olalekan O Oluwole , Anna Sureda

Investigating the Influence of Covariates on Axicabtagene Ciloleucel (axi-cel) Kinetics in Patients with Non-Hodgkin's Lymphoma.

Clinical pharmacokinetics

Avec: Magali Chartier , Simone Filosto , Thomas Peyret , Manoj Chiney , Francesca Milletti , Justin Budka , Andre Ndi , Jinghui Dong , Saran Vardhanabhuti , Daqin Mao , Stephen Duffull , Michael Dodds , Rhine Shen

IL-4 drives exhaustion of CD8

Nature communications

Avec: Carli M Stewart , Elizabeth L Siegler , R Leo Sakemura , Michelle J Cox , Truc Huynh , Brooke Kimball , Long Mai , Ismail Can , Claudia Manriquez Roman , Kun Yun , Olivia Sirpilla , James H Girsch , Ekene Ogbodo , Wazim Mohammed Ismail , Alexandre Gaspar-Maia , Justin Budka , Jenny Kim , Nathalie Scholler , Mike Mattie , Simone Filosto , Saad S Kenderian

Impact of tumor microenvironment on efficacy of anti-CD19 CAR T cell therapy or chemotherapy and transplant in large B cell lymphoma.

Nature medicine

Avec: Frederick L Locke , Simone Filosto , Justin Chou , Saran Vardhanabhuti , Regis Perbost , Peter Dreger , Brian T Hill , Catherine Lee , Pier L Zinzani , Nicolaus Kröger , Armando López-Guillermo , Hildegard Greinix , Wangshu Zhang , Gayatri Tiwari , Justin Budka , Francesco M Marincola , Christina To , Mike Mattie , Marco Schupp , Paul Cheng , Adrian Bot , Rhine Shen , Davide Bedognetti , Harry Miao , Jérôme Galon

Product attributes of CAR T-cell therapy differentially associate with efficacy and toxicity in second-line large B-cell lymphoma (ZUMA-7).

Blood cancer discovery

Avec: Simone Filosto , Saran Vardhanabhuti , Miguel A Canales , Xavier Poire , Lazaros J Lekakis , Sven de Vos , Craig A Portell , Zixing Wang , Christina To , Marco Schupp , Soumya Poddar , Tan Trinh , Carmen M Warren , Ethan G Aguilar , Justin Budka , Paul Cheng , Justin Chou , Adrian Bot , Rhine R Shen , Jason R Westin

Survival with Axicabtagene Ciloleucel in Large B-Cell Lymphoma.

The New England journal of medicine

Avec: Jason R Westin , Olalekan O Oluwole , Marie José Kersten , David B Miklos , Miguel-Angel Perales , Armin Ghobadi , Aaron P Rapoport , Anna Sureda , Caron A Jacobson , Umar Farooq , Tom van Meerten , Matthew Ulrickson , Mahmoud Elsawy , Lori A Leslie , Sridhar Chaganti , Michael Dickinson , Kathleen Dorritie , Patrick M Reagan , Joseph McGuirk , Kevin W Song , Peter A Riedell , Monique C Minnema , Yin Yang , Saran Vardhanabhuti , Simone Filosto , Paul Cheng , Shilpa A Shahani , Marco Schupp , Christina To , Frederick L Locke , Auteur inconnu , Auteur inconnu

Axicabtagene Ciloleucel in Combination with the 4-1BB Agonist Utomilumab in Patients with Relapsed/Refractory Large B-Cell Lymphoma: Phase 1 Results from ZUMA-11.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Michael D Jain , David B Miklos , Caron A Jacobson , John M Timmerman , Jennifer Sun , Jenny Nater , Xiang Fang , Ankit Patel , Madison Davis , Darren Heeke , Tan Trinh , Mike Mattie , Frank Neumann , Jenny J Kim , Christina To , Simone Filosto , Ran Reshef

Axicabtagene ciloleucel versus standard of care in second-line large B-cell lymphoma: outcomes by metabolic tumor volume.

Blood

Avec: Frederick L Locke , Olalekan O Oluwole , John Kuruvilla , Catherine Thieblemont , Franck Morschhauser , Gilles A Salles , Steven P Rowe , Saran Vardhanabhuti , Joshua Winters , Simone Filosto , Christina To , Paul Cheng , Marco Schupp , Ronald Korn , Marie José Kersten

Réseau de co-auteurs

Christina To 7 collaborations

Paul Cheng 6 collaborations

Saran Vardhanabhuti 6 collaborations

Frederick L Locke 5 collaborations

Marco Schupp 5 collaborations

David B Miklos 4 collaborations

Caron A Jacobson 4 collaborations

Olalekan O Oluwole 4 collaborations

Jason R Westin 4 collaborations

Justin Budka 4 collaborations

Miguel-Angel Perales 3 collaborations

Armin Ghobadi 3 collaborations

Aaron P Rapoport 3 collaborations

Umar Farooq 3 collaborations

Tom van Meerten 3 collaborations

Anna Sureda 3 collaborations

Michael Dickinson 3 collaborations

None None 3 collaborations

Marie José Kersten 3 collaborations

Mike Mattie 3 collaborations

Joseph McGuirk 2 collaborations

John M Pagel 2 collaborations

Patrick M Reagan 2 collaborations

Kevin W Song 2 collaborations

Monique C Minnema 2 collaborations

Peter A Riedell 2 collaborations

Lori A Leslie 2 collaborations

Sridhar Chaganti 2 collaborations

Yin Yang 2 collaborations

Jina Shah 2 collaborations

Mahmoud Elsawy 2 collaborations

Rhine Shen 2 collaborations

Justin Chou 2 collaborations

Adrian Bot 2 collaborations

Tan Trinh 2 collaborations

Marie-José Kersten 1 collaboration

Javier Muñoz 1 collaboration

Ian W Flinn 1 collaboration

Peter Vandenberghe 1 collaboration

Leo I Gordon 1 collaboration

Simon J Anderhub 1 collaboration

Grace Wing-Yan Mak 1 collaboration

Mark D Gurden 1 collaboration

Amir Faisal 1 collaboration

Konstantinos Drosopoulos 1 collaboration

Katie Walsh 1 collaboration

Hannah L Woodward 1 collaboration

Paolo Innocenti 1 collaboration

Isaac M Westwood 1 collaboration

Sébastien Naud 1 collaboration

Angela Hayes 1 collaboration

Efthymia Theofani 1 collaboration

Harry Saville 1 collaboration

Rosemary Burke 1 collaboration

Rob L M van Montfort 1 collaboration

Florence I Raynaud 1 collaboration

Julian Blagg 1 collaboration

Swen Hoelder 1 collaboration

Suzanne A Eccles 1 collaboration

Spiros Linardopoulos 1 collaboration

Matthew L Ulrickson 1 collaboration

Luciano Wannesson 1 collaboration

Lori Leslie 1 collaboration

Gerald Wulf 1 collaboration

Patrick Johnston 1 collaboration

Linqiu Du 1 collaboration

Julia T Snider 1 collaboration

Magali Chartier 1 collaboration

Thomas Peyret 1 collaboration

Manoj Chiney 1 collaboration

Francesca Milletti 1 collaboration

Andre Ndi 1 collaboration

Jinghui Dong 1 collaboration

Daqin Mao 1 collaboration

Stephen Duffull 1 collaboration

Michael Dodds 1 collaboration

Carli M Stewart 1 collaboration

Elizabeth L Siegler 1 collaboration

R Leo Sakemura 1 collaboration

Michelle J Cox 1 collaboration

Truc Huynh 1 collaboration

Brooke Kimball 1 collaboration

Long Mai 1 collaboration

Ismail Can 1 collaboration

Claudia Manriquez Roman 1 collaboration

Kun Yun 1 collaboration

Olivia Sirpilla 1 collaboration

James H Girsch 1 collaboration

Ekene Ogbodo 1 collaboration

Wazim Mohammed Ismail 1 collaboration

Alexandre Gaspar-Maia 1 collaboration

Jenny Kim 1 collaboration

Nathalie Scholler 1 collaboration

Saad S Kenderian 1 collaboration

Regis Perbost 1 collaboration

Peter Dreger 1 collaboration

Brian T Hill 1 collaboration

Catherine Lee 1 collaboration

Pier L Zinzani 1 collaboration

Nicolaus Kröger 1 collaboration

Armando López-Guillermo 1 collaboration

Hildegard Greinix 1 collaboration

Wangshu Zhang 1 collaboration

Gayatri Tiwari 1 collaboration

Francesco M Marincola 1 collaboration

Davide Bedognetti 1 collaboration

Harry Miao 1 collaboration

Jérôme Galon 1 collaboration

Miguel A Canales 1 collaboration

Xavier Poire 1 collaboration

Lazaros J Lekakis 1 collaboration

Sven de Vos 1 collaboration

Craig A Portell 1 collaboration

Zixing Wang 1 collaboration

Soumya Poddar 1 collaboration

Carmen M Warren 1 collaboration

Ethan G Aguilar 1 collaboration

Rhine R Shen 1 collaboration

Matthew Ulrickson 1 collaboration

Kathleen Dorritie 1 collaboration

Shilpa A Shahani 1 collaboration

Michael D Jain 1 collaboration

John M Timmerman 1 collaboration

Jennifer Sun 1 collaboration

Jenny Nater 1 collaboration

Xiang Fang 1 collaboration

Ankit Patel 1 collaboration

Madison Davis 1 collaboration

Darren Heeke 1 collaboration

Frank Neumann 1 collaboration

Jenny J Kim 1 collaboration

Ran Reshef 1 collaboration

John Kuruvilla 1 collaboration

Catherine Thieblemont 1 collaboration

Franck Morschhauser 1 collaboration

Gilles A Salles 1 collaboration

Steven P Rowe 1 collaboration

Joshua Winters 1 collaboration

Ronald Korn 1 collaboration