Stephan J Reshkin

Affiliations

Department of Bioscience, Biotechnology and Biopharmaceutics, University of Bari, Bari, Italy.

ORCID: http://orcid.org/0000-0001-9757-5908

Publications (29)

KRAS-regulated glutamine metabolism requires UCP2-mediated aspartate transport to support pancreatic cancer growth.

Nature metabolism

Avec: Susanna Raho , Loredana Capobianco , Rocco Malivindi , Angelo Vozza , Carmela Piazzolla , Francesco De Leonardis , Ruggiero Gorgoglione , Pasquale Scarcia , Francesca Pezzuto , Gennaro Agrimi , Simona N Barile , Isabella Pisano , Stephan J Reshkin , Maria R Greco , Rosa A Cardone , Vittoria Rago , Yuan Li , Carlo M T Marobbio , Wolfgang Sommergruber , Christopher L Riley , Francesco M Lasorsa , Edward Mills , Maria C Vegliante , Giuseppe E De Benedetto , Deborah Fratantonio , Luigi Palmieri , Vincenza Dolce , Giuseppe Fiermonte

Role of pH in Regulating Cancer Pyrimidine Synthesis.

Journal of xenobiotics

Avec: Saad Saeed Alqahtani , Tomas Koltai , Muntaser E Ibrahim , Adil H H Bashir , Sari T S Alhoufie , Samrein B M Ahmed , Daria Di Molfetta , Tiago M A Carvalho , Rosa Angela Cardone , Stephan Joel Reshkin , Abdelhameed Hifny , Mohamed E Ahmed , Khalid Omer Alfarouk

Alteration of Na/H exchange regulatory factor-1 protein levels in anogenital lesions positive for mucosal high-risk human papillomavirus type 16.

Virology

Avec: Concetta Saponaro , Luisa Galati , Tarik Gheit , Susanna Anita Pappagallo , Milena Zambetti , Francesco Alfredo Zito , Rosa Angela Cardone , Stephan Joel Reshkin , Massimo Tommasino

Genetic Signature of Human Pancreatic Cancer and Personalized Targeting.

Cells

Avec: Stephan J Reshkin , Rosa Angela Cardone , Tomas Koltai

The possible role of methylglyoxal metabolism in cancer.

Journal of enzyme inhibition and medicinal chemistry

Avec: Khalid O Alfarouk , Saad S Alqahtani , Saeed Alshahrani , Jakob Morgenstern , Claudiu T Supuran , Stephan J Reshkin

Metabolic Shifts as the Hallmark of Most Common Diseases: The Quest for the Underlying Unity.

International journal of molecular sciences

Avec: Laurent Schwartz , Marc Henry , Khalid O Alfarouk , Stephan J Reshkin , Miroslav Radman

Role of Stromal Cells in Determining Tumor and Cancer Stem Cell Behaviors and Therapeutic Response.

Cancers

Avec: Stephan J Reshkin , Rosa Angela Cardone

Semi-interpenetrating polymer network cryogels based on poly(ethylene glycol) diacrylate and collagen as potential off-the-shelf platforms for cancer cell research.

Journal of biomedical materials research. Part B, Applied biomaterials

Avec: Ugo Masullo , Anna Cavallo , Maria Raffaella Greco , Stephan J Reshkin , Maria Mastrodonato , Nunzia Gallo , Luca Salvatore , Tiziano Verri , Alessandro Sannino , Rosa Angela Cardone , Marta Madaghiele

Hydrogen Ion Dynamics as the Fundamental Link between Neurodegenerative Diseases and Cancer: Its Application to the Therapeutics of Neurodegenerative Diseases with Special Emphasis on Multiple Sclerosis.

International journal of molecular sciences

Avec: Salvador Harguindey , Khalid Alfarouk , Julián Polo Orozco , Stephan J Reshkin , Jesús Devesa

The Role of Sodium Hydrogen Exchanger 1 in Dysregulation of Proton Dynamics and Reprogramming of Cancer Metabolism as a Sequela

International journal of molecular sciences

Avec: Rosa Angela Cardone , Khalid Omer Alfarouk , Robert L Elliott , Saad Saaed Alqahtani , Samrein B M Ahmed , Ahmed N Aljarbou , Maria Raffaella Greco , Stefania Cannone , Stephan Joel Reshkin

Pathogenesis and Management of COVID-19.

Journal of xenobiotics

Avec: Khalid O Alfarouk , Sari T S AlHoufie , Samrein B M Ahmed , Mona Shabana , Ahmed Ahmed , Saad S Alqahtani , Ali S Alqahtani , Ali M Alqahtani , AbdelRahman M Ramadan , Mohamed E Ahmed , Heyam S Ali , Adil Bashir , Jesus Devesa , Rosa A Cardone , Muntaser E Ibrahim , Laurent Schwartz , Stephan J Reshkin

Resistance to Gemcitabine in Pancreatic Ductal Adenocarcinoma: A Physiopathologic and Pharmacologic Review.

Cancers

Avec: Tomas Koltai , Stephan Joel Reshkin , Tiago M A Carvalho , Daria Di Molfetta , Maria Raffaella Greco , Khalid Omer Alfarouk , Rosa Angela Cardone

Of mitochondrion and COVID-19.

Journal of enzyme inhibition and medicinal chemistry

Avec: Khalid Omer Alfarouk , Sari T S Alhoufie , Abdelhameed Hifny , Laurent Schwartz , Ali S Alqahtani , Samrein B M Ahmed , Ali M Alqahtani , Saad S Alqahtani , Abdel Khalig Muddathir , Heyam Ali , Adil H H Bashir , Muntaser E Ibrahim , Maria Raffaella Greco , Rosa A Cardone , Salvador Harguindey , Stephan Joel Reshkin

ECM Composition Differentially Regulates Intracellular and Extracellular pH in Normal and Cancer Pancreatic Duct Epithelial Cells.

International journal of molecular sciences

Avec: Daria Di Molfetta , Stefania Cannone , Maria Raffaella Greco , Rosa Caroppo , Francesca Piccapane , Tiago Miguel Amaral Carvalho , Concetta Altamura , Ilaria Saltarella , Diana Tavares Valente , Jean Francois Desaphy , Stephan J Reshkin , Rosa Angela Cardone

Acidic Growth Conditions Promote Epithelial-to-Mesenchymal Transition to Select More Aggressive PDAC Cell Phenotypes In Vitro.

Cancers

Avec: Madelaine Magalì Audero , Tiago Miguel Amaral Carvalho , Federico Alessandro Ruffinatti , Thorsten Loeck , Maya Yassine , Giorgia Chinigò , Antoine Folcher , Valerio Farfariello , Samuele Amadori , Chiara Vaghi , Albrecht Schwab , Stephan J Reshkin , Rosa Angela Cardone , Natalia Prevarskaya , Alessandra Fiorio Pla

Integrin-Linked Kinase Links Integrin Activation to Invadopodia Function and Invasion via the p(T567)-Ezrin/NHERF1/NHE1 Pathway.

International journal of molecular sciences

Avec: Maria Raffaella Greco , Loredana Moro , Stefania Forciniti , Khalid Alfarouk , Stefania Cannone , Rosa Angela Cardone , Stephan Joel Reshkin

pH-Channeling in Cancer: How pH-Dependence of Cation Channels Shapes Cancer Pathophysiology.

Cancers

Avec: Zoltán Pethő , Karolina Najder , Tiago Carvalho , Roisin McMorrow , Luca Matteo Todesca , Micol Rugi , Etmar Bulk , Alan Chan , Clemens W G M Löwik , Stephan J Reshkin , Albrecht Schwab

Targeting the Stromal Pro-Tumoral Hyaluronan-CD44 Pathway in Pancreatic Cancer.

International journal of molecular sciences

Avec: Tomas Koltai , Stephan Joel Reshkin , Tiago M A Carvalho , Rosa A Cardone

Tumor Microenvironment Modulates Invadopodia Activity of Non-Selected and Acid-Selected Pancreatic Cancer Cells and Its Sensitivity to Gemcitabine and C18-Gemcitabine.

Cells

Avec: Tiago M A Carvalho , Madelaine Magalì Audero , Maria Raffaella Greco , Marilena Ardone , Teresa Maggi , Rosanna Mallamaci , Barbara Rolando , Silvia Arpicco , Federico Alessandro Ruffinatti , Alessandra Fiorio Pla , Natalia Prevarskaya , Tomas Koltai , Stephan J Reshkin , Rosa Angela Cardone

Cancer Associated Fibroblast (CAF) Regulation of PDAC Parenchymal (CPC) and CSC Phenotypes Is Modulated by ECM Composition.

Cancers

Avec: Stefania Cannone , Maria Raffaella Greco , Tiago M A Carvalho , Helene Guizouarn , Olivier Soriani , Daria Di Molfetta , Richard Tomasini , Katrine Zeeberg , Stephan Joel Reshkin , Rosa Angela Cardone

Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer.

Nature cancer

Avec: Federica Cappellesso , Marie-Pauline Orban , Niranjan Shirgaonkar , Emanuele Berardi , Jens Serneels , Marie-Aline Neveu , Daria Di Molfetta , Francesca Piccapane , Rosa Caroppo , Lucantonio Debellis , Tessa Ostyn , Nicolas Joudiou , Lionel Mignion , Elena Richiardone , Bénédicte F Jordan , Bernard Gallez , Cyril Corbet , Tania Roskams , Ramanuj DasGupta , Sabine Tejpar , Mario Di Matteo , Daniela Taverna , Stephan J Reshkin , Baki Topal , Federico Virga , Massimiliano Mazzone

Increased demand for FAD synthesis in differentiated and stem pancreatic cancer cells is accomplished by modulating FLAD1 gene expression: the inhibitory effect of Chicago Sky Blue.

The FEBS journal

Avec: Alessia Nisco , Tiago M A Carvalho , Maria Tolomeo , Daria Di Molfetta , Piero Leone , Michele Galluccio , Milagros Medina , Cesare Indiveri , Stephan Joel Reshkin , Rosa Angela Cardone , Maria Barile

The Interplay of Dysregulated pH and Electrolyte Imbalance in Cancer.

Cancers

Avec: Khalid O Alfarouk , Samrein B M Ahmed , Ahmed Ahmed , Robert L Elliott , Muntaser E Ibrahim , Heyam S Ali , Christian C Wales , Ibrahim Nourwali , Ahmed N Aljarbou , Adil H H Bashir , Sari T S Alhoufie , Saad Saeed Alqahtani , Rosa A Cardone , Stefano Fais , Salvador Harguindey , Stephan J Reshkin

The Pentose Phosphate Pathway Dynamics in Cancer and Its Dependency on Intracellular pH.

Metabolites

Avec: Khalid O Alfarouk , Samrein B M Ahmed , Robert L Elliott , Amanda Benoit , Saad S Alqahtani , Muntaser E Ibrahim , Adil H H Bashir , Sari T S Alhoufie , Gamal O Elhassan , Christian C Wales , Laurent H Schwartz , Heyam S Ali , Ahmed Ahmed , Patrick F Forde , Jesus Devesa , Rosa A Cardone , Stefano Fais , Salvador Harguindey , Stephan J Reshkin

Phosphorylation of NHERF1 S279 and S301 differentially regulates breast cancer cell phenotype and metastatic organotropism.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Maria Raffaella Greco , Emeline Bon , Rosa Rubino , Lorenzo Guerra , Manuel Bernabe-Garcia , Stefania Cannone , Maria-Luisa Cayuela , Loredana Ciaccia , Séverine Marionneau-Lambot , Thibauld Oullier , Gaëlle Fromont , Roseline Guibon , Sébastien Roger , Stephan Joel Reshkin , Rosa Angela Cardone

Synergy Between Low Dose Metronomic Chemotherapy and the pH-centered Approach Against Cancer.

International journal of molecular sciences

Avec: Tomas Koltai , Rosa A Cardone , Stephan J Reshkin

Tumor Microenvironment Features and Chemoresistance in Pancreatic Ductal Adenocarcinoma: Insights into Targeting Physicochemical Barriers and Metabolism as Therapeutic Approaches.

Cancers

Avec: Tiago M A Carvalho , Daria Di Molfetta , Maria Raffaella Greco , Tomas Koltai , Khalid O Alfarouk , Stephan J Reshkin , Rosa A Cardone

Extracellular Matrix Composition Modulates the Responsiveness of Differentiated and Stem Pancreatic Cancer Cells to Lipophilic Derivate of Gemcitabine.

International journal of molecular sciences

Avec: Stefania Forciniti , Elisa Dalla Pozza , Maria Raffaella Greco , Tiago Miguel Amaral Carvalho , Barbara Rolando , Giulia Ambrosini , Cristian Andres Carmona-Carmona , Raffaella Pacchiana , Daria Di Molfetta , Massimo Donadelli , Silvia Arpicco , Marta Palmieri , Stephan Joel Reshkin , Ilaria Dando , Rosa Angela Cardone

Extracellular Matrix Collagen I Differentially Regulates the Metabolic Plasticity of Pancreatic Ductal Adenocarcinoma Parenchymal Cell and Cancer Stem Cell.

Cancers

Avec: Diana Tavares-Valente , Stefania Cannone , Maria Raffaella Greco , Tiago Miguel Amaral Carvalho , Fátima Baltazar , Odília Queirós , Gennaro Agrimi , Stephan J Reshkin , Rosa Angela Cardone

Réseau de co-auteurs

Rosa Angela Cardone 16 collaborations

Maria Raffaella Greco 12 collaborations

Stephan Joel Reshkin 11 collaborations

Rosa A Cardone 8 collaborations

Daria Di Molfetta 8 collaborations

Tomas Koltai 7 collaborations

Tiago M A Carvalho 7 collaborations

Samrein B M Ahmed 6 collaborations

Khalid O Alfarouk 6 collaborations

Stefania Cannone 6 collaborations

Muntaser E Ibrahim 5 collaborations

Adil H H Bashir 4 collaborations

Sari T S Alhoufie 4 collaborations

Khalid Omer Alfarouk 4 collaborations

Saad S Alqahtani 4 collaborations

Salvador Harguindey 4 collaborations

Tiago Miguel Amaral Carvalho 4 collaborations

Laurent Schwartz 3 collaborations

Robert L Elliott 3 collaborations

Ahmed Ahmed 3 collaborations

Heyam S Ali 3 collaborations

Gennaro Agrimi 2 collaborations

Saad Saeed Alqahtani 2 collaborations

Abdelhameed Hifny 2 collaborations

Mohamed E Ahmed 2 collaborations

Khalid Alfarouk 2 collaborations

Ahmed N Aljarbou 2 collaborations

Ali S Alqahtani 2 collaborations

Ali M Alqahtani 2 collaborations

Jesus Devesa 2 collaborations

Rosa Caroppo 2 collaborations

Francesca Piccapane 2 collaborations

Madelaine Magalì Audero 2 collaborations

Federico Alessandro Ruffinatti 2 collaborations

Albrecht Schwab 2 collaborations

Natalia Prevarskaya 2 collaborations

Alessandra Fiorio Pla 2 collaborations

Stefania Forciniti 2 collaborations

Barbara Rolando 2 collaborations

Silvia Arpicco 2 collaborations

Christian C Wales 2 collaborations

Stefano Fais 2 collaborations

Susanna Raho 1 collaboration

Loredana Capobianco 1 collaboration

Rocco Malivindi 1 collaboration

Angelo Vozza 1 collaboration

Carmela Piazzolla 1 collaboration

Francesco De Leonardis 1 collaboration

Ruggiero Gorgoglione 1 collaboration

Pasquale Scarcia 1 collaboration

Francesca Pezzuto 1 collaboration

Simona N Barile 1 collaboration

Isabella Pisano 1 collaboration

Maria R Greco 1 collaboration

Vittoria Rago 1 collaboration

Yuan Li 1 collaboration

Carlo M T Marobbio 1 collaboration

Wolfgang Sommergruber 1 collaboration

Christopher L Riley 1 collaboration

Francesco M Lasorsa 1 collaboration

Edward Mills 1 collaboration

Maria C Vegliante 1 collaboration

Giuseppe E De Benedetto 1 collaboration

Deborah Fratantonio 1 collaboration

Luigi Palmieri 1 collaboration

Vincenza Dolce 1 collaboration

Giuseppe Fiermonte 1 collaboration

Concetta Saponaro 1 collaboration

Luisa Galati 1 collaboration

Tarik Gheit 1 collaboration

Susanna Anita Pappagallo 1 collaboration

Milena Zambetti 1 collaboration

Francesco Alfredo Zito 1 collaboration

Massimo Tommasino 1 collaboration

Saeed Alshahrani 1 collaboration

Jakob Morgenstern 1 collaboration

Claudiu T Supuran 1 collaboration

Marc Henry 1 collaboration

Miroslav Radman 1 collaboration

Ugo Masullo 1 collaboration

Anna Cavallo 1 collaboration

Maria Mastrodonato 1 collaboration

Nunzia Gallo 1 collaboration

Luca Salvatore 1 collaboration

Tiziano Verri 1 collaboration

Alessandro Sannino 1 collaboration

Marta Madaghiele 1 collaboration

Julián Polo Orozco 1 collaboration

Jesús Devesa 1 collaboration

Saad Saaed Alqahtani 1 collaboration

Sari T S AlHoufie 1 collaboration

Mona Shabana 1 collaboration

AbdelRahman M Ramadan 1 collaboration

Adil Bashir 1 collaboration

Abdel Khalig Muddathir 1 collaboration

Heyam Ali 1 collaboration

Concetta Altamura 1 collaboration

Ilaria Saltarella 1 collaboration

Diana Tavares Valente 1 collaboration

Jean Francois Desaphy 1 collaboration

Thorsten Loeck 1 collaboration

Maya Yassine 1 collaboration

Giorgia Chinigò 1 collaboration

Antoine Folcher 1 collaboration

Valerio Farfariello 1 collaboration

Samuele Amadori 1 collaboration

Chiara Vaghi 1 collaboration

Loredana Moro 1 collaboration

Zoltán Pethő 1 collaboration

Karolina Najder 1 collaboration

Tiago Carvalho 1 collaboration

Roisin McMorrow 1 collaboration

Luca Matteo Todesca 1 collaboration

Micol Rugi 1 collaboration

Etmar Bulk 1 collaboration

Alan Chan 1 collaboration

Clemens W G M Löwik 1 collaboration

Marilena Ardone 1 collaboration

Teresa Maggi 1 collaboration

Rosanna Mallamaci 1 collaboration

Helene Guizouarn 1 collaboration

Olivier Soriani 1 collaboration

Richard Tomasini 1 collaboration

Katrine Zeeberg 1 collaboration

Federica Cappellesso 1 collaboration

Marie-Pauline Orban 1 collaboration

Niranjan Shirgaonkar 1 collaboration

Emanuele Berardi 1 collaboration

Jens Serneels 1 collaboration

Marie-Aline Neveu 1 collaboration

Lucantonio Debellis 1 collaboration

Tessa Ostyn 1 collaboration

Nicolas Joudiou 1 collaboration

Lionel Mignion 1 collaboration

Elena Richiardone 1 collaboration

Bénédicte F Jordan 1 collaboration

Bernard Gallez 1 collaboration

Cyril Corbet 1 collaboration

Tania Roskams 1 collaboration

Ramanuj DasGupta 1 collaboration

Sabine Tejpar 1 collaboration

Mario Di Matteo 1 collaboration

Daniela Taverna 1 collaboration

Baki Topal 1 collaboration

Federico Virga 1 collaboration

Massimiliano Mazzone 1 collaboration

Alessia Nisco 1 collaboration

Maria Tolomeo 1 collaboration

Piero Leone 1 collaboration

Michele Galluccio 1 collaboration

Milagros Medina 1 collaboration

Cesare Indiveri 1 collaboration

Maria Barile 1 collaboration

Ibrahim Nourwali 1 collaboration

Amanda Benoit 1 collaboration

Gamal O Elhassan 1 collaboration

Laurent H Schwartz 1 collaboration

Patrick F Forde 1 collaboration

Emeline Bon 1 collaboration

Rosa Rubino 1 collaboration

Lorenzo Guerra 1 collaboration

Manuel Bernabe-Garcia 1 collaboration

Maria-Luisa Cayuela 1 collaboration

Loredana Ciaccia 1 collaboration

Séverine Marionneau-Lambot 1 collaboration

Thibauld Oullier 1 collaboration

Gaëlle Fromont 1 collaboration

Roseline Guibon 1 collaboration

Sébastien Roger 1 collaboration

Elisa Dalla Pozza 1 collaboration

Giulia Ambrosini 1 collaboration

Cristian Andres Carmona-Carmona 1 collaboration

Raffaella Pacchiana 1 collaboration

Massimo Donadelli 1 collaboration

Marta Palmieri 1 collaboration

Ilaria Dando 1 collaboration

Diana Tavares-Valente 1 collaboration

Fátima Baltazar 1 collaboration

Odília Queirós 1 collaboration